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Germs Dec 2021Emphysematous endocarditis is caused by the gas-forming organisms , , species, and . We report the first case of emphysematous endocarditis caused by .
INTRODUCTION
Emphysematous endocarditis is caused by the gas-forming organisms , , species, and . We report the first case of emphysematous endocarditis caused by .
CASE REPORT
An 82-year-old man presented with fever and rapidly progressive shortness of breath. He was found to be in atrial fibrillation with rapid ventricular rates. Two-dimensional transthoracic echocardiography demonstrated severe mitral regurgitation. Subsequent two- and three-dimensional transesophageal echocardiogram revealed a large, highly mobile vegetation on the atrial surface of the anterior mitral leaflet with aneurysmal destruction of the lateral scallop requiring mitral valve replacement. Sequencing of the vegetation revealed an anaerobic gram-positive coccus that, in rare cases, produces gas using a heme-dependent catalase. Histopathological analysis of the infected valve suggested interstitial gas accumulation, leading to the diagnosis of emphysematous endocarditis.
CONCLUSIONS
associated emphysematous endocarditis should be included in the differential diagnosis of valvular vegetation in patients with a rapidly progressing clinical course. When possible, histopathological analysis should be used alongside other imaging techniques to confirm the diagnosis of emphysematous endocarditis. This case also highlights the importance of collecting blood cultures prior to initiating antibiotic treatment.
PubMed: 35096679
DOI: 10.18683/germs.2021.1297 -
Respiratory Medicine Case Reports 2023is a gram-positive anaerobic coccus (GPAC) that colonizes the oral cavity and gastrointestinal tract. Recent advances in bacterial identification have confirmed the...
is a gram-positive anaerobic coccus (GPAC) that colonizes the oral cavity and gastrointestinal tract. Recent advances in bacterial identification have confirmed the clinical importance of . Here, we report a case of empyema with bacteremia caused by . We successfully treated the patient with the appropriate antibiotics and drainage. can cause respiratory infections, including empyema, which can progress to bacteremia if treatment is delayed. In infections, not only the oral cavity but also the entire body must be investigated to clarify the entry mechanism.
PubMed: 37577121
DOI: 10.1016/j.rmcr.2023.101892 -
New Microbes and New Infections Jan 2017Strain Marseille-P2915, a Gram-positive, facultative anaerobic and nonmotile coccus, was isolated from the gastric lavage of a patient with severe anaemia. The 16S rRNA...
Strain Marseille-P2915, a Gram-positive, facultative anaerobic and nonmotile coccus, was isolated from the gastric lavage of a patient with severe anaemia. The 16S rRNA and gene comparison exhibited a sequence identity of 98.7 and 92.6% with strain JCM 10157, respectively, collocating it within the group. On the basis of phenotypic and genomic analysis, we propose the validation of the type strain sp. nov. Marseille-P2915T (= DSM 103349 = CSUR P2915).
PubMed: 28050252
DOI: 10.1016/j.nmni.2016.11.013 -
Current Microbiology Feb 2024The strains Marseille-Q7072 (= CSUR Q7072 = CECT 30604) and Marseille-Q7826 (= CSUR Q7826 = CECT 30727) were isolated from vaginal samples. As MALDI-TOF mass...
The strains Marseille-Q7072 (= CSUR Q7072 = CECT 30604) and Marseille-Q7826 (= CSUR Q7826 = CECT 30727) were isolated from vaginal samples. As MALDI-TOF mass spectrometry failed to identify them, their genomes were directly sequenced to determine their taxogenomic identities. Both strains are anaerobic without any oxidase and catalase activity. C is the most abundant fatty acid for both strains. Strain Marseille-Q7072 is non-spore-forming, non-motile, Gram-stain-positive, and coccus-shaped, while strain Marseille-Q7826 is non-spore-forming, motile, Gram-stain-variable, and curved rod-shaped. The genomic comparison of the Marseille-Q7072 and Marseille-Q7826 strains showed that all digital DNA-DNA hybridisation (dDDH) and mean orthologous nucleotide identity (OrthoANI) values were below published species thresholds (70% and 95-96%, respectively) with other closely related species with standing in nomenclature. Thus, we conclude that both strains are new bacterial species. Strain Marseille-Q7072 is a new member of the Bacillota phylum, for which the name Peptoniphilus genitalis sp. nov. is proposed, while the Marseille-Q7826 strain is a new member of the Actinomycetota phylum, for which the name Mobiluncus massiliensis sp. nov. is proposed.
Topics: Female; Humans; Mobiluncus; Bacteria; Clostridiales; Microbiota; DNA
PubMed: 38372813
DOI: 10.1007/s00284-023-03584-7 -
Journal of Orthopaedic Case Reports 2018Anaerobic vertebral osteomyelitis has been reported rarely. In this report, we describe an extremely rare case of a patient who suffered from vertebral osteomyelitis...
INTRODUCTION
Anaerobic vertebral osteomyelitis has been reported rarely. In this report, we describe an extremely rare case of a patient who suffered from vertebral osteomyelitis caused by Peptostreptococcus micros.
CASE REPORT
A 73-year-old man with a history of diabetes mellitus was admitted to our hospital with a 5-month history of severe low back pain. A radiograph of the lumbar spine demonstrated intervertebral disc space narrowing with indistinct end plates at the L3-L4 level. T2-weighted magnetic resonance image showed high signal intensity at L3-L4 intervertebral disc space. We suspected pyogenic spondylitis and performed percutaneous posterolateral endoscopic debridement. The results of intraoperative sample cultures were positive for P. micros, an anaerobic Gram-positive coccus. He was treated by the antibiotic therapy. Low back pain resolved and his white blood cell count and C-reactive protein levels remained normal with the combination therapy. During 2-year follow-up, he reported no low back pain and had no signs of infection recurrence.
CONCLUSION
If a patient who was in immunodepression status develops severe back pain, the clinician should be suspicious of the possibility of spondylitis by P. micros and start antibiotic therapy after undergoing sample collection.
PubMed: 30584506
DOI: 10.13107/jocr.2250-0685.1084 -
Journal of Spine Surgery (Hong Kong) Mar 2023() is an anaerobic Gram-positive coccus, common commensal of the gastrointestinal tract of animals and humans. Anaerobic organisms as etiologic agents of bone and joint...
BACKGROUND
() is an anaerobic Gram-positive coccus, common commensal of the gastrointestinal tract of animals and humans. Anaerobic organisms as etiologic agents of bone and joint infections (BJI) are uncommon and frequently underestimated. New technologies, such as mass spectrometry techniques and molecular techniques like 16S rRNA, allow for more efficient diagnosis of these anaerobic bacteria. We present the first case report of deep surgical site infection (SSI) due to , following spinal surgery.
CASE DESCRIPTION
We report the case of a deep SSI caused by following posterior spinal instrumentation in an 81-year-old woman. The patient underwent extension of her previous fusion L2-L5, due to adjacent segment disease (ASD). We performed a T10 to S2-alar-iliac instrumentation. During the postoperative period, the patient presented with a paralytic ileus that required the placement of a nasogastric tube followed by gastrointestinal bleeding and two gastroscopies. Subsequently the patient showed signs of deep SSI. We performed surgical irrigation and debridement. All six cultures in anaerobic media showed short Gram-positive diplococci, using matrix-assisted laser desorption/ionization time of flight mass spectrometry (Maldi-TOF MS) all six strains were identified as . The patient was treated with amoxicilin 1 g/8 h and ciprofloxacin 750 mg/12 h for 4 weeks. Six months postoperative, she was asymptomatic.
CONCLUSIONS
As is the case with our patient, all previously described cases of infection had a history of intestinal disease or immunosupression. We believe the isolation of should raise the possibility of intestinal injury. Immunosuppression is also an important risk factor for the development of infection.
PubMed: 37038414
DOI: 10.21037/jss-22-81 -
New Microbes and New Infections May 2016Strain FF10(T) (= CSUR P1489 = DSM 100884) was isolated from the oral cavity of a lizard (Varanus niloticus) in Dakar, Senegal. Here we used a polyphasic study...
Strain FF10(T) (= CSUR P1489 = DSM 100884) was isolated from the oral cavity of a lizard (Varanus niloticus) in Dakar, Senegal. Here we used a polyphasic study including phenotypic and genomic analyses to describe the strain FF10(T). Results support strain FF10(T) being a Gram-positive coccus, facultative anaerobic bacterium, catalase-negative, non-motile and non-spore forming. The sequenced genome counts 2.46 Mb with one chromosome but no plasmid. It exhibits a G+C content of 40.4% and contains 2471 protein-coding and 45 RNA genes. On the basis of these data, we propose the creation of Streptococcus varani sp. nov.
PubMed: 27158513
DOI: 10.1016/j.nmni.2016.03.004 -
Microorganisms Dec 2023is an aerobic Gram-positive coccus that grows as tiny alpha-hemolytic colonies. is a slow-growing facultative anaerobic Gram-positive rod. These bacteria are part of...
is an aerobic Gram-positive coccus that grows as tiny alpha-hemolytic colonies. is a slow-growing facultative anaerobic Gram-positive rod. These bacteria are part of the urogenital microbiota of healthy patients, but can also be involved in urinary tract infections (UTIs), particularly in elderly men and young children. Because and are fastidious and are difficult to identify with phenotypic methods, they are underestimated causes of UTIs. Their growth is slow and requires a blood-enriched medium incubated under an anaerobic or 5% CO atmosphere for 48 h and from 24 to 48 h for and , respectively. Furthermore, accurate identification is only possible using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) or molecular-based methods. In rare cases, these bacteria can be responsible for invasive infections. We describe, here, an unusual case of bacteremic UTI caused by both and in an 89-year-old woman. She presented with dyspnea, and bacteriuria was noted. This challenging clinical and microbiological diagnosis was made in our laboratory by Gram staining urine with a leucocyte count >50/μL and/or a bacterial count >14/μL urinary culture on a blood agar plate. After 10 days of antimicrobial treatment consisting of 2 g amoxicillin PO t.i.d., the patient was discharged with a complete clinical and biological recovery. and are probably still underestimated causes of UTIs. Microbiologists could consider the presence of these two bacteria using appropriate culture and identification methods in cases where a positive direct examination of urine reveals small Gram-positive rods or cocci, where undocumented UTIs are present in elderly patients, but also where a urinary dipstick is negative for nitrites and is associated with leukocyturia.
PubMed: 38138052
DOI: 10.3390/microorganisms11122908 -
Anaerobe Dec 2020Veillonella dispar is a Gram-negative anaerobic coccus involved in only a few human diseases. We report the second case of bacteremia due to this microorganism in an...
Veillonella dispar is a Gram-negative anaerobic coccus involved in only a few human diseases. We report the second case of bacteremia due to this microorganism in an elderly patient. A 72-year-old man with a history of bladder cancer presented with diarrhea, vomiting, and fever for 48 hours. After the diagnosis of septic shock, four sets of blood cultures were taken, and three of them yielded V. dispar. Resistance to metronidazole, penicillin, and piperacillin-tazobactam was documented. Treatment with clindamycin was started, and the patient was discharged after improvement in his general condition.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Comorbidity; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; RNA, Ribosomal, 16S; Urinary Bladder Neoplasms; Veillonella
PubMed: 33075505
DOI: 10.1016/j.anaerobe.2020.102285 -
Cureus Jan 2023is a Gram-positive anaerobic found in soil that is a rare cause of inflammatory infections of the GI tract. This bacterium has a propensity for causing gastritis in...
is a Gram-positive anaerobic found in soil that is a rare cause of inflammatory infections of the GI tract. This bacterium has a propensity for causing gastritis in patients with delayed gastric emptying. Of the 66 reported cases in the literature, 10 involved the esophagus. Symptoms of an esophageal infection are non-specific and may be mistaken for long-standing gastroesophageal reflux. We present a case of a 67-year-old female with chronic dysphagia and reflux diagnosed with erosive esophagitis caused by . Treatment strategies documented in the literature are reviewed.
PubMed: 36852351
DOI: 10.7759/cureus.34230