-
The Science of the Total Environment Jan 2024Fish and seafood products are one of the most common causes of listeriosis in humans. A systematic review and meta-analysis were conducted using scientific literature to... (Meta-Analysis)
Meta-Analysis Review
Fish and seafood products are one of the most common causes of listeriosis in humans. A systematic review and meta-analysis were conducted using scientific literature to summarize available data on the prevalence of Listeria monocytogenes and Listeria sp. in fish, fish products and fish processing environment. Meta-analysis models were used to estimate the mean prevalence of the pathogen and to compare prevalence among the most popular fishes. Data from a total of 14,496 samples were analysed. Pooled prevalence of L. monocytogenes and Listeria sp. in raw fish was 5.8 % (95 % CI: 4.7-6.9) and 12.2 % (95 % CI: 8.9-15.5) respectively. Significantly higher results were observed for ready-to-eat products, occurrence of L. monocytogenes and Listeria sp. was 14.5 % (95 % CI: 11.1-18.0) and 21.7 % (95 % CI: 11.8-31.6) respectively. Moreover, meta-regression was performed to investigate changes in L. monocytogenes and Listeria sp. occurrence over the years and it shows a downward trend for both raw fish and RTE products. The results of the present study provide useful epidemiological information about the contamination level and distribution of Listeria sp. and L. monocytogenes among raw fish, fish products and fish processing environment.
Topics: Humans; Animals; Listeria monocytogenes; Listeria; Food Microbiology; Food Contamination; Prevalence; Fish Products; Fishes
PubMed: 37866612
DOI: 10.1016/j.scitotenv.2023.167912 -
Le Infezioni in Medicina 2023Listeriosis is a known cause of community acquired bacterial meningitis/meningoencephalitis. It occurs more frequently in neonates, older people and immunocompromised...
BACKGROUND
Listeriosis is a known cause of community acquired bacterial meningitis/meningoencephalitis. It occurs more frequently in neonates, older people and immunocompromised hosts. Rarely, brain abscesses can complicate the course of infection, which poses a difficulty in the management and elevates morbidity and mortality. Myasthenia gravis is an autoimmune disease that often requires immunosuppressive treatment, which increases the risk for invasive infections.
CASE DESCRIPTION
A 75-year-old myasthenic patient, treated with prednisone and pyridostigmine, was diagnosed with invasive listeriosis. He presented with muscle weakness, dyspnea, hemiparesis and altered mental status. Brain imaging revealed multiple abscesses and blood cultures were positive for . Despite combination antibiotic therapy, he died 6 weeks after admission.
SYSTEMATIC REVIEW
Ninety-six cases of brain abscesses from 1968 to 2023 were reviewed; the majority of the patients were men, 54 years-old on average, and had at least one risk factor for invasive listeriosis. The mortality exceeded 22%. Blood cultures and CSF/abscess cultures were positive in only 79.2% and 54.6%, respectively. The most common therapeutic approach was a combination regimen that included amoxicillin or ampicillin. Only 8 patients underwent surgery, of which one died.
CONCLUSION
This case highlights the importance of as a cause of brain abscesses in populations at risk, including myasthenic patients. The challenge of diagnosing and treating this condition is aggravated by the paucity of literature and the high mortality rate.
PubMed: 38075415
DOI: 10.53854/liim-3104-16 -
International Journal of Food... Apr 2024Listeria monocytogenes is a foodborne pathogen that can cause deadly severe listeriosis. While systematic review and meta-analysis are powerful tools for comprehensive... (Meta-Analysis)
Meta-Analysis
Listeria monocytogenes is a foodborne pathogen that can cause deadly severe listeriosis. While systematic review and meta-analysis are powerful tools for comprehensive analysis by pooling every related study, these approaches to L.monocytogenes contamination food have yet to be studied in South Korea. We aimed to identify high-risk L.monocytogenes foods in South Korea through a prevalence survey of retail food products for the first time. A total of 13,684 samples of 59 articles were used for meta-analysis through the systematic review, and the results were synthesized using a random-effects model considering the heterogeneity. The overall pooled prevalence was 2.26 % (95 % CI: 1.44-3.52 %). Among nine food categories, meat exhibited the highest prevalence at 8.32 % (95 % CI: 4.42-12.14 %) after sample size restriction. Specifically, a post-hoc sensitivity analysis was conducted to identify the prevalence difference among subgroups and the source of heterogeneity. Intriguingly, the analysis revealed chicken as the primary contributor to the elevated prevalence of L.monocytogenes, a key factor deriving the observed heterogeneity. This study carries significant implications for public health and food safety in Korea. Furthermore, knowledge of differences in prevalence levels in various foods will be able to be used as a predictive guideline for foodborne outbreaks.
Topics: Humans; Listeria monocytogenes; Food Microbiology; Prevalence; Listeriosis; Food Contamination; Republic of Korea
PubMed: 38430686
DOI: 10.1016/j.ijfoodmicro.2024.110655