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Deutsches Arzteblatt International Dec 2023
Topics: Humans; Bowen's Disease; Human papillomavirus 16; Warts; Skin Neoplasms; Papillomaviridae
PubMed: 38287916
DOI: 10.3238/arztebl.m2023.0121 -
International Journal of Surgery Case... Feb 2024Dermal Regeneration Templates may be used in the reconstruction of large skin defects after cutaneous malignancy excisions. Bowen's disease (BD; squamous cell carcinoma...
INTRODUCTION
Dermal Regeneration Templates may be used in the reconstruction of large skin defects after cutaneous malignancy excisions. Bowen's disease (BD; squamous cell carcinoma in situ) is a common and persistent condition that can be related to chronic sun damage, and consequently, is usually located on the head and neck area or on the lower limbs. Literature does not provide clear guidelines on the treatment of BD, limiting itself to describing a wide range of different methods that can be used, including surgery, laser therapy or topical options. However, large lesions tend to scar in the post-operative setting and hence are difficult to treat surgically.
PRESENTATION OF CASE
In this paper the authors present a case of a male in his 60s, ASA III score, who presented with a history of histopathologically-confirmed squamocellular carcinoma in the neck and supraclavicular region. Due to recurrent carcinomas the patient was treated with an extensive skin excision and a successful reconstruction using a Dermal Regeneration Template. The work has been reported in line with the SCARE criteria.
DISCUSSION
The main surgical problem caused by BD is reaching complete oncological resection and, consequently, the need for extensive skin excisions.
CONCLUSION
The use of the skin substitute resulted in a satisfactory functional and aesthetic result, with total clearance and no recurrence observed after 16 months.
PubMed: 38199019
DOI: 10.1016/j.ijscr.2023.109208 -
Photodiagnosis and Photodynamic Therapy Feb 2024Bowenoid Papulosis (BP) is an anogenital pre-malignancy. BP with immunosuppression may recur, worsen, or possibly evolve into squamous cell carcinoma or Bowen's disease...
Bowenoid Papulosis (BP) is an anogenital pre-malignancy. BP with immunosuppression may recur, worsen, or possibly evolve into squamous cell carcinoma or Bowen's disease (BD), and it may also become resistant to conventional treatment. Here, we describe a complex case of BP together with BD and Diffuse Large B-Cell Lymphoma that was effectively treated with a holmium laser in conjunction with 5-Aminolevulinic Acid Photodynamic Therapy (ALA-PDT). The lesion totally vanished and the affected area remained intact with no recurrence at five years.
Topics: Humans; Aminolevulinic Acid; Photochemotherapy; Lasers, Solid-State; Photosensitizing Agents; Skin Neoplasms; Carcinoma, Squamous Cell; Bowen's Disease; Precancerous Conditions; Lymphoma, Large B-Cell, Diffuse
PubMed: 38145769
DOI: 10.1016/j.pdpdt.2023.103953 -
Photodiagnosis and Photodynamic Therapy Apr 2024Hematoporphyrin injection (HpD) mediated photodynamic therapy (PDT) has demonstrated efficacy in treating various types of Bowen's disease, including basal-cell...
Hematoporphyrin injection (HpD) mediated photodynamic therapy (PDT) has demonstrated efficacy in treating various types of Bowen's disease, including basal-cell carcinoma, squamous cell carcinoma, extramammary Paget's disease, and actinic keratosis. We present a case of a male patient who developed squamous cell carcinoma as a result of repeated instances of arsenic-induced keratosis on both his hands and feet. Due to the involvement of the joint in both hands, the patient declined the conventional surgical resection treatment since it could potentially impact normal physiological function. Instead, the patient chose to undergo hemoporphyrin photodynamic therapy. After the treatment, the rash was entirely eliminated and there were no restrictions in the movement of the joint. Nevertheless, a local recurrence was detected throughout the two-year monitoring period. Arsenical keratosis carries a substantial likelihood of recurring. However, we believe that hemoporphyrin photodynamic therapy is effective in treating this condition.
Topics: Humans; Male; Photochemotherapy; Carcinoma, Squamous Cell; Photosensitizing Agents; Hematoporphyrins; Skin Neoplasms; Keratosis; Aged
PubMed: 38552815
DOI: 10.1016/j.pdpdt.2024.104071 -
Acta Dermato-venereologica Sep 2023
Topics: Humans; Human Papillomavirus Viruses; Bowen's Disease; Sexual Partners; Skin Neoplasms
PubMed: 37731214
DOI: 10.2340/actadv.v103.13439