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European Journal of Investigation in... Dec 2023According to the neo-functional developmental theory, newborns and infants exhibit complex psycho-bodily functioning. The Basic Experiences of the Self (BEsS) refer to...
According to the neo-functional developmental theory, newborns and infants exhibit complex psycho-bodily functioning. The Basic Experiences of the Self (BEsS) refer to how they fulfil their essential life needs by organising their psycho-bodily functions in a typical configuration. As part of our research study, we developed a prototype psychometric tool called the BEsS Assessment Form (BAF) to assess the BEsS in infants aged zero to three years. We collected video recordings of their spontaneous behaviour and used the BAF to evaluate function polarity. In the BAF, thirty pairs of words represent functions in their dyadic polarity. To estimate the level of function polarity, we used the Osgood semantic differential scale, which ranges from seven to one. The study's results confirm that functions can be assessed by grading along the opposite polarity spectrum. Moreover, in accordance with the theory, the functions can be grouped into four domains: the emotional, postural motor, physiological, and cognitive-symbolic planes. Our findings suggest that the characteristics of BEsS are significantly influenced by the activation of the physiological and postural motor functions, which are related to the early regulation of the autonomic nervous system and can be used to evaluate infant arousal.
PubMed: 38131897
DOI: 10.3390/ejihpe13120198 -
Linguistics Nov 2023In this work we are presenting a database structure to encode the phenomenon of differential possession across languages, considering noun possession classes and...
In this work we are presenting a database structure to encode the phenomenon of differential possession across languages, considering noun possession classes and possessive constructions as independent but linked. We show how this structure can be used to study different dimensions of possession: semantics, noun valence, and possessive constructions. We present preliminary survey results from a global sample of 120 languages and show that there is a universal semantic core in both inalienable and non-possessible noun classes. Inalienables are centered on body parts and kinship. Non-possessibles are centered on animals, humans, and natural elements.
PubMed: 38144363
DOI: 10.1515/ling-2022-0021 -
Seizure Jan 2024A clinical decision tool for Transient Loss of Consciousness (TLOC) could reduce currently high misdiagnosis rates and waiting times for specialist assessments. Most...
OBJECTIVE
A clinical decision tool for Transient Loss of Consciousness (TLOC) could reduce currently high misdiagnosis rates and waiting times for specialist assessments. Most clinical decision tools based on patient-reported symptom inventories only distinguish between two of the three most common causes of TLOC (epilepsy, functional /dissociative seizures, and syncope) or struggle with the particularly challenging differentiation between epilepsy and FDS. Based on previous research describing differences in spoken accounts of epileptic seizures and FDS seizures, this study explored the feasibility of predicting the cause of TLOC by combining the automated analysis of patient-reported symptoms and spoken TLOC descriptions.
METHOD
Participants completed an online web application that consisted of a 34-item medical history and symptom questionnaire (iPEP) and spoken interaction with a virtual agent (VA) that asked eight questions about the most recent experience of TLOC. Support Vector Machines (SVM) were trained using different combinations of features and nested leave-one-out cross validation. The iPEP provided a baseline performance. Inspired by previous qualitative research three spoken language based feature sets were designed to assess: (1) formulation effort, (2) the proportion of words from different semantic categories, and (3) verb, adverb, and adjective usage.
RESULTS
76 participants completed the application (Epilepsy = 24, FDS = 36, syncope = 16). Only 61 participants also completed the VA interaction (Epilepsy = 20, FDS = 29, syncope = 12). The iPEP model accurately predicted 65.8 % of all diagnoses, but the inclusion of the language features increased the accuracy to 85.5 % by improving the differential diagnosis between epilepsy and FDS.
CONCLUSION
These findings suggest that an automated analysis of TLOC descriptions collected using an online web application and VA could improve the accuracy of current clinical decisions tools for TLOC and facilitate clinical stratification processes (such as ensuring appropriate referral to cardiological versus neurological investigation and management pathways).
Topics: Humans; Seizures; Syncope; Unconsciousness; Epilepsy; Surveys and Questionnaires; Diagnosis, Differential
PubMed: 38091849
DOI: 10.1016/j.seizure.2023.11.022 -
Cognitive Processing Aug 2023This study aimed to examine whether Japanese participants condition spoken words' meanings to written pseudowords. In Survey 1, we selected spoken words associated with...
This study aimed to examine whether Japanese participants condition spoken words' meanings to written pseudowords. In Survey 1, we selected spoken words associated with negative (α = .91) and positive (α = .79) features for Experiment 1 and passive (α = .90) and active (α = .80) features for Experiment 2. In Experiment 1, participants evaluated four written pseudowords' emotional valence using a 7-point semantic differential scale (1: negative; 7: positive) before and after conditioning spoken words with negative, neutral, or positive features to each pseudoword. In the conditioning phase, participants read each pseudoword, listened to a spoken word, and verbally repeated each spoken word. The results showed that a pseudoword was conditioned to spoken words with positive and negative features. In Experiment 2, participants evaluated four pseudowords' activeness using a 7-point semantic differential scale (1: passive; 7: active) before and after conditioning spoken words of passive, neutral, and active features to each written pseudoword. In the conditioning phase, the participants read each written pseudoword, listened to a spoken word, and repeated the spoken word. The results showed that the activeness evaluations were more increased for pseudowords conditioned to spoken words of active and neutral features after conditioning than before conditioning but were unchanged for a pseudoword conditioned to those with passive features before and after conditioning. Additonally, Survey 2's results showed that although the positiveness and activeness responses of the words used in Experiments 1 and 2 were controlled well, the lack of significant differences among positiveness responses of words may influence the evaluative conditioning in Experiment 2. That is, when participants condition passive (low arousal) words' activeness (arousal) ratings to those of pseudowords, words' positiveness (valence) ratings would be important in the evaluative conditioning. Our findings suggest that participants can condition spoken word meanings of preference and activeness to those of written pseudowords. It also indicates that linguistically evaluative conditioning's effects are robust in a non-alphabetic language.
Topics: Humans; Auditory Perception; East Asian People; Emotions; Language; Reading; Writing; Speech; Language Arts
PubMed: 37450232
DOI: 10.1007/s10339-023-01138-0 -
Frontiers in Psychology 2024Nowadays there are multiple ways to perceive music, from attending concerts (live) to listening to recorded music through headphones (medial). In between there are many...
Nowadays there are multiple ways to perceive music, from attending concerts (live) to listening to recorded music through headphones (medial). In between there are many mixed modes, such as playback performances. In empirical music research, this plurality of performance forms has so far found little recognition. Until now no measuring instrument has existed that could adequately capture the differences in perception and aesthetic judgment. The purpose of our empirical investigation was to capture all dimensions relevant to such an assessment. Using 3D-simulations and dynamic binaural synthesis, various live and medial situations were simulated. A qualitative survey was conducted at the Department of Audio Communication of the Technical University of Berlin (TU Berlin). With the help of the repertory grid technique, a data pool of approximately 400 attribute pairs was created and individual rating data were collected. Our first study served to create a semantic differential. In a second study, this semantic differential was evaluated. The development of the semantic differential was carried out by first using a mixed-method approach to qualitative analysis according to grounded theory. Thereafter, a principal component analysis reduced the attribute pairs to 67 items in four components. The semantic differential consists of items concerning acoustic, visual and audio-visual interaction as well as items with an overarching assessment of the stimuli. The evaluation study, comprising 45 participants (23 male and 22 female, = 42.56 years, = 17.16) who rated 12 stimuli each, reduced the items to 61 and resulted in 18 subscales and nine single items. Because the survey used simulations, the social component may be underrepresented. Nevertheless, the questionnaire we created enables the evaluation of music performances (especially for classical concerts) in a new scope, thus opening many opportunities for further research. For example, in a live concert context, we observed not only that seating position influences the judgment of sound quality but also that visual elements influence immersion and felt affect. In the future, the differential could be reviewed for a larger stimulus pool, extended or used modularly for different research questions.
PubMed: 38629034
DOI: 10.3389/fpsyg.2024.1339168 -
Scientific Reports Apr 2024This study aimed to investigate the effects of reproducing an ultrasonic sound above 20 kHz on the subjective impressions of water sounds using psychological and...
This study aimed to investigate the effects of reproducing an ultrasonic sound above 20 kHz on the subjective impressions of water sounds using psychological and physiological information obtained by the semantic differential method and electroencephalography (EEG), respectively. The results indicated that the ultrasonic component affected the subjective impression of the water sounds. In addition, regarding the relationship between psychological and physiological aspects, a moderate correlation was confirmed between the EEG change rate and subjective impressions. However, no differences in characteristics were found between with and without the ultrasound component, suggesting that ultrasound does not directly affect the relationship between subjective impressions and EEG energy at the current stage. Furthermore, the correlations calculated for the left and right channels in the occipital region differed significantly, which suggests functional asymmetry for sound perception between the right and left hemispheres.
Topics: Sound; Hearing; Electroencephalography; Auditory Perception; Acoustic Stimulation
PubMed: 38561365
DOI: 10.1038/s41598-024-57749-w -
Diagnostics (Basel, Switzerland) Jul 2023The segmentation of gastrointestinal (GI) organs is crucial in radiation therapy for treating GI cancer. It allows for developing a targeted radiation therapy plan while...
The segmentation of gastrointestinal (GI) organs is crucial in radiation therapy for treating GI cancer. It allows for developing a targeted radiation therapy plan while minimizing radiation exposure to healthy tissue, improving treatment success, and decreasing side effects. Medical diagnostics in GI tract organ segmentation is essential for accurate disease detection, precise differential diagnosis, optimal treatment planning, and efficient disease monitoring. This research presents a hybrid encoder-decoder-based model for segmenting healthy organs in the GI tract in biomedical images of cancer patients, which might help radiation oncologists treat cancer more quickly. Here, EfficientNet B0 is used as a bottom-up encoder architecture for downsampling to capture contextual information by extracting meaningful and discriminative features from input images. The performance of the EfficientNet B0 encoder is compared with that of three encoders: ResNet 50, MobileNet V2, and Timm Gernet. The Feature Pyramid Network (FPN) is a top-down decoder architecture used for upsampling to recover spatial information. The performance of the FPN decoder was compared with that of three decoders: PAN, Linknet, and MAnet. This paper proposes a segmentation model named as the Feature Pyramid Network (FPN), with EfficientNet B0 as the encoder. Furthermore, the proposed hybrid model is analyzed using Adam, Adadelta, SGD, and RMSprop optimizers. Four performance criteria are used to assess the models: the Jaccard and Dice coefficients, model loss, and processing time. The proposed model can achieve Dice coefficient and Jaccard index values of 0.8975 and 0.8832, respectively. The proposed method can assist radiation oncologists in precisely targeting areas hosting cancer cells in the gastrointestinal tract, allowing for more efficient and timely cancer treatment.
PubMed: 37510142
DOI: 10.3390/diagnostics13142399 -
Psychonomic Bulletin & Review Feb 2024Understanding visual narrative sequences, as found in comics, is known to recruit similar cognitive mechanisms to verbal language. As measured by event-related... (Review)
Review
Understanding visual narrative sequences, as found in comics, is known to recruit similar cognitive mechanisms to verbal language. As measured by event-related potentials (ERPs), these manifest as initial negativities (N400, LAN) and subsequent positivities (P600). While these components are thought to index discrete processing stages, they differentially arise across participants for any given stimulus. In language contexts, proficiency modulates brain responses, with smaller N400 effects and larger P600 effects appearing with increasing proficiency. In visual narratives, recent work has also emphasized the role of proficiency in neural response patterns. We thus explored whether individual differences in proficiency modulate neural responses to visual narrative sequencing in similar ways as in language. We combined ERP data from 12 studies examining semantic and/or grammatical processing of visual narrative sequences. Using linear mixed effects modeling, we demonstrate differential effects of visual language proficiency and "age of acquisition" on N400 and P600 responses. Our results align with those reported in language contexts, providing further evidence for the similarity of linguistic and visual narrative processing, and emphasize the role of both proficiency and age of acquisition in visual narrative comprehension.
Topics: Humans; Male; Female; Evoked Potentials; Comprehension; Electroencephalography; Individuality; Language; Brain; Semantics
PubMed: 37578688
DOI: 10.3758/s13423-023-02334-x -
PloS One 2024Android malware is becoming more common, and its invasion of smart devices has brought immeasurable losses to people's lives. Most existing Android malware detection...
Android malware is becoming more common, and its invasion of smart devices has brought immeasurable losses to people's lives. Most existing Android malware detection methods extract Android features from the original application files without considering the high-order hidden information behind them, but these hidden information can reflect malicious behaviors. To solve this problem, this paper proposes Z2F, a detection framework based on multidimensional Android feature extraction and graph neural networks for Android applications. Z2F first extracts seven types of Android features from the original Android application and then embeds them into a heterogeneous graph. On this basis, we design 12 kinds of meta-structures to analyze different semantic spaces of heterogeneous graphs, mine high-order hidden semantic information, and adopt a multi-layer graph attention mechanism to iteratively embed and update information. In this paper, a total of 14429 Android applications were detected and 1039726 Android features were extracted, with a detection accuracy of 99.7%.
Topics: Humans; Neural Networks, Computer; Records; Semantic Differential; Semantics
PubMed: 38547074
DOI: 10.1371/journal.pone.0300975 -
Brain Communications 2024The posterior cingulate cortex (PCC) is a key hub of the default mode network underlying autobiographical memory retrieval, which falters early in the progression of...
The posterior cingulate cortex (PCC) is a key hub of the default mode network underlying autobiographical memory retrieval, which falters early in the progression of Alzheimer's disease (AD). We recently performed RNA sequencing of post-mortem PCC tissue samples from 26 elderly Rush Religious Orders Study participants who came to autopsy with an ante-mortem diagnosis of no cognitive impairment but who collectively displayed a range of Braak I-IV neurofibrillary tangle stages. Notably, cognitively unimpaired subjects displaying high Braak stages may represent cognitive resilience to AD pathology. Transcriptomic data revealed elevated synaptic and ATP-related gene expression in Braak Stages III/IV compared with Stages I/II, suggesting these pathways may be related to PCC resilience. We also mined expression profiles for small non-coding micro-RNAs (miRNAs), which regulate mRNA stability and may represent an underexplored potential mechanism of resilience through the fine-tuning of gene expression within complex cellular networks. Twelve miRNAs were identified as differentially expressed between Braak Stages I/II and III/IV. However, the extent to which the levels of all identified miRNAs were associated with subject demographics, neuropsychological test performance and/or neuropathological diagnostic criteria within this cohort was not explored. Here, we report that a total of 667 miRNAs are significantly associated (rho > 0.38, < 0.05) with subject variables. There were significant positive correlations between miRNA expression levels and age, perceptual orientation and perceptual speed. By contrast, higher miRNA levels correlated negatively with semantic and episodic memory. Higher expression of 15 miRNAs associated with lower Braak Stages I-II and 47 miRNAs were associated with higher Braak Stages III-IV, suggesting additional mechanistic influences of PCC miRNA expression with resilience. Pathway analysis showed enrichment for miRNAs operating in pathways related to lysine degradation and fatty acid synthesis and metabolism. Finally, we demonstrated that the 12 resilience-related miRNAs differentially expressed in Braak Stages I/II versus Braak Stages III/IV were predicted to regulate mRNAs related to amyloid processing, tau and inflammation. In summary, we demonstrate a dynamic state wherein differential PCC miRNA levels are associated with cognitive performance and post-mortem neuropathological AD diagnostic criteria in cognitively intact elders. We posit these relationships may inform miRNA transcriptional alterations within the PCC relevant to potential early protective (resilience) or pathogenic (pre-clinical or prodromal) responses to disease pathogenesis and thus may be therapeutic targets.
PubMed: 38572270
DOI: 10.1093/braincomms/fcae082