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Biosemiotics Apr 2012The present paper proposes a definition for the complex polysemic concepts of consciousness and awareness (in humans as well as in other species), and puts forward the...
The present paper proposes a definition for the complex polysemic concepts of consciousness and awareness (in humans as well as in other species), and puts forward the idea of a progressive ontological development of consciousness from a state of 'childhood' awareness, in order to explain that humans are not only able to manipulate objects, but also their mental representations. The paper builds on the idea of qualia intended as entities posing regular invariant requests to neural processes, trough the permanence of different properties. The concept of semantic differential introduces the properties of metaphorical qualia as an exclusively human ability. Furthermore this paper proposes a classification of qualia, according to the models-with different levels of abstraction-they are implied in, in a taxonomic perspective. This, in turn, becomes a source of categorization of divergent representations, sign systems, and forms of intentionality, relying always on biological criteria. New emerging image-of-the-world-devices are proposed, whose qualia are likely to be only accessible to humans: emotional qualia, where emotion accounts for the invariant and dominant property; and the qualic self where continuity, combined with the oneness of the self, accounts for the invariant and dominant property. The concept of congruence between different domains in a metaphor introduces the possibility of a general evaluation of truth and falsity of all kinds of metaphorical constructs, while the work of Matte Blanco enables us to classify conscious versus unconscious metaphors, both in individuals and in social organizations.
PubMed: 22347988
DOI: 10.1007/s12304-011-9116-2 -
The British Journal of Social Psychology Jan 2023Word embeddings provide quantitative representations of word semantics and the associations between word meanings in text data, including in large repositories in media... (Review)
Review
Word embeddings provide quantitative representations of word semantics and the associations between word meanings in text data, including in large repositories in media and social media archives. This article introduces social psychologists to word embedding research via a consideration of bias analysis, a topic of central concern in the discipline. We explain how word embeddings are constructed and how they can be used to measure bias along bipolar dimensions that are comparable to semantic differential scales. We review recent studies that show how familiar social biases can be detected in embeddings and how these change over time and in conjunction with real-world discriminatory practices. The evidence suggests that embeddings yield valid and reliable estimates of bias and that they can identify subtle biases that may not be communicated explicitly. We argue that word embedding research can extend scholarship on prejudice and stereotyping, providing measures of the bias environment of human thought and action.
Topics: Humans; Semantics; Prejudice; Stereotyping
PubMed: 35871272
DOI: 10.1111/bjso.12560 -
American Journal of Alzheimer's Disease... Nov 2015Frontotemporal dementia (FTD) was one of the lesser known dementias until the recent advancements revealing its genetic and pathological foundation. This common... (Review)
Review
Frontotemporal dementia (FTD) was one of the lesser known dementias until the recent advancements revealing its genetic and pathological foundation. This common neurodegenerative disorder has three clinical subtypes- behavioral, semantic and progressive non fluent aphasia. The behavioral variant mostly exhibits personality changes, while the other two encompass various language deficits. This review discusses the basic pathology, genetics, clinical and histological presentation and the diagnosis of the 3 subtypes. It also deliberates the different therapeutic modalities currently available for frontotemporal dementia and the challenges faced by the caregivers. Lastly it explores the scope of further research into the diagnosis and management of FTD.
Topics: Behavior; Caregivers; Diagnosis, Differential; Frontotemporal Dementia; Humans; Pick Disease of the Brain
PubMed: 23813692
DOI: 10.1177/1533317513494442 -
Frontiers in Artificial Intelligence 2023In recent years, with the rapid development of deep learning technology, great progress has been made in computer vision, image recognition, pattern recognition, and... (Review)
Review
In recent years, with the rapid development of deep learning technology, great progress has been made in computer vision, image recognition, pattern recognition, and speech signal processing. However, due to the black-box nature of deep neural networks (DNNs), one cannot explain the parameters in the deep network and why it can perfectly perform the assigned tasks. The interpretability of neural networks has now become a research hotspot in the field of deep learning. It covers a wide range of topics in speech and text signal processing, image processing, differential equation solving, and other fields. There are subtle differences in the definition of interpretability in different fields. This paper divides interpretable neural network (INN) methods into the following two directions: model decomposition neural networks, and semantic INNs. The former mainly constructs an INN by converting the analytical model of a conventional method into different layers of neural networks and combining the interpretability of the conventional model-based method with the powerful learning capability of the neural network. This type of INNs is further classified into different subtypes depending on which type of models they are derived from, i.e., mathematical models, physical models, and other models. The second type is the interpretable network with visual semantic information for user understanding. Its basic idea is to use the visualization of the whole or partial network structure to assign semantic information to the network structure, which further includes convolutional layer output visualization, decision tree extraction, semantic graph, etc. This type of method mainly uses human visual logic to explain the structure of a black-box neural network. So it is a post-network-design method that tries to assign interpretability to a black-box network structure afterward, as opposed to the pre-network-design method of model-based INNs, which designs interpretable network structure beforehand. This paper reviews recent progress in these areas as well as various application scenarios of INNs and discusses existing problems and future development directions.
PubMed: 37899962
DOI: 10.3389/frai.2023.974295 -
BMC Medical Informatics and Decision... Feb 2022Semantic similarity is a valuable tool for analysis in biomedicine. When applied to phenotype profiles derived from clinical text, they have the capacity to enable and...
BACKGROUND
Semantic similarity is a valuable tool for analysis in biomedicine. When applied to phenotype profiles derived from clinical text, they have the capacity to enable and enhance 'patient-like me' analyses, automated coding, differential diagnosis, and outcome prediction. While a large body of work exists exploring the use of semantic similarity for multiple tasks, including protein interaction prediction, and rare disease differential diagnosis, there is less work exploring comparison of patient phenotype profiles for clinical tasks. Moreover, there are no experimental explorations of optimal parameters or better methods in the area.
METHODS
We develop a platform for reproducible benchmarking and comparison of experimental conditions for patient phentoype similarity. Using the platform, we evaluate the task of ranking shared primary diagnosis from uncurated phenotype profiles derived from all text narrative associated with admissions in the medical information mart for intensive care (MIMIC-III).
RESULTS
300 semantic similarity configurations were evaluated, as well as one embedding-based approach. On average, measures that did not make use of an external information content measure performed slightly better, however the best-performing configurations when measured by area under receiver operating characteristic curve and Top Ten Accuracy used term-specificity and annotation-frequency measures.
CONCLUSION
We identified and interpreted the performance of a large number of semantic similarity configurations for the task of classifying diagnosis from text-derived phenotype profiles in one setting. We also provided a basis for further research on other settings and related tasks in the area.
Topics: Humans; Phenotype; ROC Curve; Rare Diseases; Semantics
PubMed: 35123470
DOI: 10.1186/s12911-022-01770-4 -
Journal of Alzheimer's Disease : JAD 2023Semantic and Phonological fluency (SF and PF) are routinely evaluated in patients with Alzheimer's disease (AD). There are disagreements in the literature regarding... (Meta-Analysis)
Meta-Analysis
BACKGROUND
Semantic and Phonological fluency (SF and PF) are routinely evaluated in patients with Alzheimer's disease (AD). There are disagreements in the literature regarding which fluency task is more affected while developing AD. Most studies focus on SF assessment, given its connection with the temporoparietal amnesic system. PF is less reported, it is related to working memory, which is also impaired in probable and diagnosed AD. Differentiating between performance on these tasks might be informative in early AD diagnosis, providing an accurate linguistic profile.
OBJECTIVE
Compare SF and PF performance in healthy volunteers, volunteers with probable AD, and patients with AD diagnosis, considering the heterogeneity of age, gender, and educational level variables.
METHODS
A total of 8 studies were included for meta-analysis, reaching a sample size of 1,270 individuals (568 patients diagnosed with AD, 340 with probable AD diagnosis, and 362 healthy volunteers).
RESULTS
The three groups consistently performed better on SF than PF. When progressing to a diagnosis of AD, we observed a significant difference in SF and PF performance across our 3 groups of interest (p = 0.04). The age variable explained a proportion of this difference in task performance across the groups, and as age increases, both tasks equally worsen.
CONCLUSION
The performance of SF and PF might play a differential role in early AD diagnosis. These tasks rely on partially different neural bases of language processing. They are thus worth exploring independently in diagnosing normal aging and its transition to pathological stages, including probable and diagnosed AD.
Topics: Humans; Semantics; Alzheimer Disease; Verbal Behavior; Neuropsychological Tests; Linguistics
PubMed: 37482994
DOI: 10.3233/JAD-221272 -
Medicina (Kaunas, Lithuania) Oct 2021: It is widely agreed that patients suffering from Alzheimer's disease (AD) and patients suffering from semantic dementia (SD) might fail clinically administered...
: It is widely agreed that patients suffering from Alzheimer's disease (AD) and patients suffering from semantic dementia (SD) might fail clinically administered semantic tasks due to a different combination of underlying cognitive deficits: namely, degraded semantic representations in SD and degraded representations plus executive control deficit in AD. However, no easy administrable test or test battery for differentiating the semantic impairment profile in these populations has been devised yet. : In this study, we propose a new easy administrable task based on a free association procedure (F-Assoc) to be used in conjunction with category fluency (Cat-Fl) and letter fluency (Lett-Fl) for quantifying pure representational and pure control deficits, thus teasing apart the semantic profile of SD and AD patients. : In a sample of 10 AD and 10 SD subjects, matched for disease severity, we show that indices of asymmetric performance contrasting F-Assoc and each of the two verbal fluency tasks yield a clearly distinguishable discrepancy pattern across SD and AD. We also provide empirical support for the validity of an asymmetry measure contrasting F-Assoc and Cat-FL as an index of control impairment. : The present study suggests that the free association procedure provides a pure measure of degradation of semantic representations avoiding the confound of possible concomitant executive deficits.
Topics: Alzheimer Disease; Free Association; Frontotemporal Dementia; Humans; Neuropsychological Tests; Semantics
PubMed: 34833389
DOI: 10.3390/medicina57111171 -
Materials (Basel, Switzerland) Feb 2023Biobased composites offer unique properties in the context of sustainable material production as well as end-of-life disposal, which places them as viable alternatives...
Biobased composites offer unique properties in the context of sustainable material production as well as end-of-life disposal, which places them as viable alternatives to fossil-fuel-based materials. However, the large-scale application of these materials in product design is hindered by their perceptual handicaps and understanding the mechanism of biobased composite perception, and its constituents could pave the way to creating commercially successful biobased composites. This study examines the role of bimodal (visual and tactile) sensory evaluation in the formation of biobased composite perception through the Semantic Differential method. It is observed that the biobased composites could be grouped into different clusters based on the dominance and interplay of various senses in perception forming. Attributes such as , , and are seen to correlate with each other positively and are influenced by both visual and tactile characteristics of the biobased composites. Attributes such as , , and are also positively correlated but dominated by visual stimuli. The perceptual relationships and components of beauty, naturality, and value and their constituent attributes are identified, along with the visual and tactile characteristics that influence these assessments. Material design leveraging these biobased composite characteristics could lead to the creation of sustainable materials that would be more attractive to designers and consumers.
PubMed: 36902959
DOI: 10.3390/ma16051844 -
Wiley Interdisciplinary Reviews.... Jul 2022The three human at-rest postures of sitting, standing, and lying are basic, recurring features of human behavior and may reasonably be called primary postures. The three... (Review)
Review
The three human at-rest postures of sitting, standing, and lying are basic, recurring features of human behavior and may reasonably be called primary postures. The three postures share the property of being stable through time, but they are also differentiated in terms of their overall shape, their physiological properties, and typical associated behaviors such as the association of sitting with social interaction, and lying with sleeping. The experiential realities of the three postures underlie and motivate a range of cross-linguistic phenomena involving morphemes with meanings of "sit", "stand," and "lie". The relevant linguistic phenomena include higher frequencies of occurrence compared with other kinds of posture verbs and differential behavior with respect to some morphosyntactic patterns involving notions such as agentivity. The posture morphemes can also be the source for a variety of semantic extensions reflecting experiential realities of the postures, such as the extension of "lie" to mean "sleep" in some languages. Extensions also include grammaticalizations of the posture morphemes to locative and aspectual markers which reflect the temporal stability and spatial fixedness of the postures themselves. This article is categorized under: Linguistics > Cognitive Linguistics Linguistics > Language in Mind and Brain.
Topics: Brain; Humans; Linguistics; Motivation; Posture; Sleep
PubMed: 35106947
DOI: 10.1002/wcs.1592 -
Journal of Neuropsychology Sep 2016There are a number of long-standing theories on how the cognitive processing of abstract words, like 'life', differs from that of concrete words, like 'knife'. This... (Review)
Review
There are a number of long-standing theories on how the cognitive processing of abstract words, like 'life', differs from that of concrete words, like 'knife'. This review considers current perspectives on this debate, focusing particularly on insights obtained from patients with language disorders and integrating these with evidence from functional neuroimaging studies. The evidence supports three distinct and mutually compatible hypotheses. (1) Concrete and abstract words differ in their representational substrates, with concrete words depending particularly on sensory experiences and abstract words on linguistic, emotional, and magnitude-based information. Differential dependence on visual versus verbal experience is supported by the evidence for graded specialization in the anterior temporal lobes for concrete versus abstract words. In addition, concrete words have richer representations, in line with better processing of these words in most aphasic patients and, in particular, patients with semantic dementia. (2) Abstract words place greater demands on executive regulation processes because they have variable meanings that change with context. This theory explains abstract word impairments in patients with semantic-executive deficits and is supported by neuroimaging studies showing greater response to abstract words in inferior prefrontal cortex. (3) The relationships between concrete words are governed primarily by conceptual similarity, while those of abstract words depend on association to a greater degree. This theory, based primarily on interference and priming effects in aphasic patients, is the most recent to emerge and the least well understood. I present analyses indicating that patterns of lexical co-occurrence may be important in understanding these effects.
Topics: Cognition; Comprehension; Concept Formation; Female; Humans; Male; Neuropsychological Tests; Neuropsychology; Semantics; Vocabulary
PubMed: 25708527
DOI: 10.1111/jnp.12065