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Clinical Child and Family Psychology... Jun 2021In recent years, there has been a proliferation of research regarding transgender and gender nonconforming (TGNC) people. The stigma and legal discriminations that this... (Review)
Review
In recent years, there has been a proliferation of research regarding transgender and gender nonconforming (TGNC) people. The stigma and legal discriminations that this population faces have obvious and documented repercussions for mental health. In 2015, the American Psychological Association (APA) published Guidelines for Psychological Practice with TGNC People. The APA noted that due to the nuances of working with TGNC youth and the dearth of related literature, the guidelines focus primarily on TGNC adults. To date, there has not been a systematic review of risk and resilience factors for mental health among TGNC children, adolescents, and young adults under the age of 25. Forty-four peer-reviewed articles met inclusion criteria for this systematic review, and were evaluated for their methodological rigor and their findings. Common risk factors for negative mental health variables included physical and verbal abuse, exposure to discrimination, social isolation, poor peer relations, low self-esteem, weight dissatisfaction, and age. Across studies, older children and adolescents tended to report higher rates of psychological distress. Resilience-promoting factors for mental health were also documented, including parent connectedness, social support, school safety and belonging, and the ability to use one's chosen name. By synthesizing the existing literature using a resilience-focused and minority stress framework, the present review provides clinicians and researchers with a coherent evidence-base to better equip them to promote psychological adaptation and wellbeing among TGNC youth.
Topics: Adolescent; Child; Gender Identity; Humans; Mental Health; Protective Factors; Social Support; Transgender Persons; Young Adult
PubMed: 33594611
DOI: 10.1007/s10567-021-00344-6 -
Annals of Medicine Dec 2023Hepatic encephalopathy (HE) implies high morbidity and mortality. The assessment of covert HE (CHE) [i.e. minimal HE (MHE) plus grade 1 HE] is often neglected in Taiwan....
BACKGROUND AND AIMS
Hepatic encephalopathy (HE) implies high morbidity and mortality. The assessment of covert HE (CHE) [i.e. minimal HE (MHE) plus grade 1 HE] is often neglected in Taiwan. Therefore, the aim was to investigate the potential of the animal naming test (ANT and simplified ANT (S-ANT) for assessing CHE in Chinese-speaking regions, specifically Taiwan.
METHODS
A prospective cohort study was conducted, comprising 65 cirrhotic patients and 29 healthy controls (relatives of the patients). Patients were followed up every three months and censored after two years or until death. Hospitalization for overt HE (OHE) and mortality were considered. All subjects underwent ANT, psychometric HE score (PHES), and mini-mental state examination (MMSE). The patients underwent an electroencephalogram (EEG) to detect slowing indicative of MHE. Cut-off values for ANT and S-ANT were assessed by ROC analysis and Youden's index, considering CHE as a reference. The prognostic values for OHE and OHE-free survival were assessed.
RESULTS
Preliminary analysis confirmed that PHES ≤-4 is a good discriminant point for abnormal results. CHE was found in 29 patients: 9 had MHE (PHES ≤ -4 or altered EEG) and 20 had grade 1 HE. ANT and S-ANT were found to have diagnostic values for CHE: AUC = 0.807, 0.786; cut off: 18 and 19, respectively. ANT and S-ANT were found to have prognostic value for OHE, number of hospitalization episodes for OHE, and OHE recurrence-free survival.
CONCLUSIONS
ANT shows promise as a tool for CHE detection, quantification, and follow-up in Taiwan and other Chinese-speaking regions.Key messagesThe animal naming test (ANT) is a simple and valid semantic fluency test that can be easily performed in outpatient or bedside settings in one minute and can also be used as a tool for covert hepatic encephalopathy (CHE) detection, quantification, and follow-up in Taiwan, other Chinese-speaking regions, and many other countries.The diagnostic value of ANT and S-ANT for CHE were found to be significant, with area under the receiver operating characteristic curve (AUROC) values of 0.807 and 0.786 respectively, and cut-off scores of 18 and 19.ANT and S-ANT have prognostic value for the first breakthrough of overt hepatic encephalopathy (OHE), number of hospitalization episodes for OHE, and OHE recurrence-free survival, independent of the MELD score.
Topics: Animals; Humans; East Asian People; Hepatic Encephalopathy; Liver Cirrhosis; Prospective Studies; ROC Curve; Names
PubMed: 37494454
DOI: 10.1080/07853890.2023.2236013 -
Health Policy (Amsterdam, Netherlands) Apr 2020Brand-name medicines have dominated the Portuguese market for several decades with unquestionable exclusivity. This resulted particularly from the absence of a... (Review)
Review
Brand-name medicines have dominated the Portuguese market for several decades with unquestionable exclusivity. This resulted particularly from the absence of a requirement of prescriptions by international non-proprietary name. To promote the enhancement of both efficiency and sustainability in the health system, the Portuguese government introduced the generics in Portugal by the 90 s. However, only in the first decade of the 21 century were some policies implemented to increase their market share. Although some expectations were created, the use of generics has increased moderately during that period, in which policies to promote them were consolidated by imposing the austerity principles in the midst of the economic and social crisis. This study analyses the main policy measures already implemented as well as the incentives created for the replacement of brand-name medicines with generics. In addition, the present study also makes some recommendations to promote a broader and better use of generics in Portugal.
Topics: Drugs, Generic; Humans; Motivation; Portugal
PubMed: 32139170
DOI: 10.1016/j.healthpol.2020.02.014 -
JCO Oncology Practice Oct 2021
Topics: Humans; Names; Neoplasms; Parents; Patient-Centered Care
PubMed: 33734827
DOI: 10.1200/OP.20.00588 -
International Journal of Environmental... Apr 2022The objective of this systematic review is to make an inventory of the representations of the professionals of specialized institutions on the sexuality of persons with... (Review)
Review
The objective of this systematic review is to make an inventory of the representations of the professionals of specialized institutions on the sexuality of persons with intellectual disabilities. The scientific studies were identified according to the PRISMA protocol using 18 databases, with keywords on sexuality and parenthood. Studies were reviewed through a methodological assessment and then a thematic analysis. Twenty-four studies were reviewed and three themes were identified: professionals' representations of gender, sexuality, and consent; professionals' perceptions of their role in supporting people's sexual lives; and the ways in which professionals construct representations of people's sexual lives. This corpus highlights deep paradoxes in the representations of professionals concerning the socio-affective needs and sexuality of people with intellectual disabilities, creating what we could define as a "system of incompatibility" and leading to difficulties in positioning. Support is still too random and subject to control logics in the name of protecting users, who are perceived as vulnerable. Training and new ways of teamwork appear to be central to supporting the evolution of the representations and practices of professionals. Future research anchored in practices and involving users as well as professionals is necessary to better understand the paradoxical aspects of professionals' representations and to draw alternative ways of constructing these representations.
Topics: Gender Identity; Humans; Intellectual Disability; Persons with Mental Disabilities; Sexual Behavior; Sexuality
PubMed: 35457641
DOI: 10.3390/ijerph19084771 -
PloS One 2022Racial disparity in academia is a widely acknowledged problem. The quantitative understanding of racial-based systemic inequalities is an important step towards a more...
Racial disparity in academia is a widely acknowledged problem. The quantitative understanding of racial-based systemic inequalities is an important step towards a more equitable research system. However, because of the lack of robust information on authors' race, few large-scale analyses have been performed on this topic. Algorithmic approaches offer one solution, using known information about authors, such as their names, to infer their perceived race. As with any other algorithm, the process of racial inference can generate biases if it is not carefully considered. The goal of this article is to assess the extent to which algorithmic bias is introduced using different approaches for name-based racial inference. We use information from the U.S. Census and mortgage applications to infer the race of U.S. affiliated authors in the Web of Science. We estimate the effects of using given and family names, thresholds or continuous distributions, and imputation. Our results demonstrate that the validity of name-based inference varies by race/ethnicity and that threshold approaches underestimate Black authors and overestimate White authors. We conclude with recommendations to avoid potential biases. This article lays the foundation for more systematic and less-biased investigations into racial disparities in science.
Topics: Bias; Censuses; Ethnicity; Humans; Names; United States
PubMed: 35231059
DOI: 10.1371/journal.pone.0264270 -
Journal of the American Academy of... Oct 2020An impressive surge in research supporting a shift to a dimensional organization of psychopathology has occurred over the last two decades. This has culminated in recent...
An impressive surge in research supporting a shift to a dimensional organization of psychopathology has occurred over the last two decades. This has culminated in recent calls for the abolishment of the categorical diagnostic system in favor of a quantitative classification system for psychopathology. The use of diagnostic constructs such as borderline personality disorder (BPD), and perhaps even the concept of personality pathology itself, may disappear from such nosological systems and be redefined in terms of internalizing-externalizing-psychoticism spectra. Indeed, the original International Classification of Diseases, 11th Revision (ICD-11) proposal eliminated the traditional 10 personality disorders and introduced a definition of personality disorder based on severity rather than type. It may therefore be argued that the study conducted by Wertz et al., which focuses on borderline personality disorder, is out of step with current trends in psychiatric nosology. Moreover, Wertz and colleagues focus on adolescents-a developmental period often characterized as inappropriate for the diagnosis and treatment of personality disorder. On the contrary, this editorial will argue that Wertz et al. make a timely and important contribution by highlighting the importance of adolescent personality pathology for prospective psychosocial function.
Topics: Adolescent; Adult; Borderline Personality Disorder; Child; Cohort Studies; Humans; Longitudinal Studies; Personality; Personality Disorders; Prospective Studies
PubMed: 31654694
DOI: 10.1016/j.jaac.2019.10.007 -
International Journal of Radiation... Jun 2021Introducing a physician without a professional title may reinforce bias in medicine by influencing perceived credibility. We evaluated differences in the use of... (Observational Study)
Observational Study
PURPOSE
Introducing a physician without a professional title may reinforce bias in medicine by influencing perceived credibility. We evaluated differences in the use of professional titles in introductions of speakers at recent American Society for Radiation Oncology (ASTRO) Annual Meetings.
METHODS AND MATERIALS
We reviewed recordings from the 2017 to 2019 ASTRO Annual Meetings and included complete introductions of speakers with a doctoral degree. Professional introduction was defined as "Doctor" or "Professor" followed by the speaker's full or last name. We collected use of professional introduction, introducer gender, speaker gender, and speaker professional and demographic variables. Identified speakers were sent surveys to collect self-reported demographic data. Analysis was performed using χ tests and multivariable logistic regression (MVA).
RESULTS
Of 3267 presentations reviewed, 1226 (38%) met the inclusion criteria. Overall, 805 (66%) speakers and 710 (58%) introducers were men. Professional introductions were used in 74% (2017), 71% (2018), and 69% (2019) of the presentations. There was no difference in the use of professional introductions for male and female speakers (71% vs 73%; P = .550). On MVA, male introducers were associated with decreased use of professional address (odds ratio [OR], 0.36; 95% confidence interval [CI], 0.26-0.49; P < .001). At the 2019 conference, professional introduction was less likely to be used (2019 vs 2017: OR, 0.68; 95% CI, 0.49-0.96; P = 0.026). Those who self-identified as Asian/Pacific Islander were twice as likely to receive a professional introduction compared with those who identified as white (OR, 1.95; 95% CI, 1.07-3.64; P = .033).
CONCLUSION
Male introducers were significantly less likely to introduce any speaker, regardless of gender, by their professional title, and overall use of professional introductions decreased from 2017 to 2019. Furthermore, no difference in professional introduction use by speaker gender was identified at the recent ASTRO meetings. Implementing speaker guidelines could increase the use of professional introductions and raise awareness of unconscious bias at future ASTRO meetings.
Topics: Asian People; Bias; Black People; Chi-Square Distribution; Congresses as Topic; Cross-Sectional Studies; Educational Status; Female; Hispanic or Latino; Humans; Indians, North American; Logistic Models; Male; Names; Racism; Radiation Oncology; Retrospective Studies; Sex Factors; Sexism; Societies, Medical; United States; White People
PubMed: 33373658
DOI: 10.1016/j.ijrobp.2020.12.027 -
Computers in Biology and Medicine Oct 2023As the main technology to solve data islands and mine data value, federated learning has been widely researched and applied, and more and more federated learning...
As the main technology to solve data islands and mine data value, federated learning has been widely researched and applied, and more and more federated learning platforms are emerging. The federated learning platform organizes users, devices and data to collaborate in a crowdsourcing manner and complete specific federated learning tasks. This paper designs the shortest path core-selection incentive mechanism by combining the VCG auction mechanism and the core concept of cooperative games. This mechanism solves the problems of overpayment, false-name attack, and deviation from the core of the VCG mechanism, and saves the expenditure of the federated learning task issuer. It adopts the VCG-nearest principle in the core selection, so that the federated learning task participants get rewards as close as possible to the outcome of VCG mechanism. This mechanism can guarantee four economic attributes: incentive compatibility, individual rationality, alliance rationality, and maximization of social efficiency. Medical experimental results illustrate the effectiveness of the mechanism.
Topics: Humans; Motivation; Learning; Health Expenditures
PubMed: 37678134
DOI: 10.1016/j.compbiomed.2023.107394 -
Acta Psychologica Oct 2019Previous studies have shown that stimuli with subjective salience could affect duration estimation. Although self-referential stimuli possess high biological and social...
Previous studies have shown that stimuli with subjective salience could affect duration estimation. Although self-referential stimuli possess high biological and social importance, no prior study has examined whether and how self-referential information affects duration perception. Experiment 1 used the temporal bisection task to investigate participants' duration estimation of the presentation of their own name versus familiar and unfamiliar names. The results showed that participants overestimated the duration of their own name and became more sensitive to duration perception in such trials when compared with stranger's names. Given the specificity of personal name, Experiment 2 used two types of personality-trait words in self-referential and friend-referential manner as the targets of duration perception. The duration of self-referential negative trait words was perceived to be longer relative to friend-referential negative trait words. The mechanism underlying the subjective time dilation effect of self-referential information possibly involves the engagement of increased attentional resources, which could allow the individual to preserve a certain level of stability and positivity of self-knowledge.
Topics: Adult; Attention; Female; Humans; Male; Names; Random Allocation; Self Concept; Time Perception; Young Adult
PubMed: 31707077
DOI: 10.1016/j.actpsy.2019.102934