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Advances in Neonatal Care : Official... Feb 2022Research about skin-to-skin care (SSC) experiences in early period after birth has focused on mothers and infants. (Meta-Analysis)
Meta-Analysis
BACKGROUND
Research about skin-to-skin care (SSC) experiences in early period after birth has focused on mothers and infants.
PURPOSE
The purpose of this study was to determine the outcomes of paternal skin-to-skin care (P-SSC) in both fathers and infants.
METHODS
The Cochrane Central Register of Controlled Trials (CENTRAL), PubMed/MEDLINE, Embase, CINAHL, PsycInfo, Airiti Library, and Google Scholar were searched for randomized controlled trials (RCTs) that reported outcomes of P-SSC in both fathers and infants. We calculated pooled mean differences (MDs) and 95% confidence intervals (CIs) using RevMan 5.3 for the meta-analysis [PROSPERO: CRD42018106790].
RESULTS
Seven RCTs including a total of 552 participants were eligible for inclusion. Compared to the maternal skin-to-skin care (M-SSC), fathers in the P-SSC exhibited no significant differences in salivary oxytocin levels (MD: -0.35 pg/mL; 95% CI: -0.75, 0.05), salivary cortisol levels (MD: 0.25 μg/dL; 95% CI: -0.82, 1.33), or anxiety scores (MD: -0.17; 95% CI: -0.57, 0.22) during the period of SSC. Similarly, there were no significant differences in the salivary cortisol levels (MD: -0.11 μg/dL; 95% CI: -0.05, 0.28) among preterm infants between the 2 groups. However, the crying time was less among full-term infants in the P-SSC group compared with infants in the incubator care or cot care groups.
IMPLICATIONS FOR PRACTICE AND RESEARCH
P-SSC had similar effects as M-SSC on stress-related outcomes during and after SSC among fathers and infants in the early stages after birth. We recommend that P-SSC be implemented in the early stages after birth. Further RCTs with a longitudinal design and large samples are needed to better understand the long-term effects of P-SSC on fathers and infants.
Topics: Child; Fathers; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Kangaroo-Mother Care Method; Male; Mothers; Skin Care
PubMed: 34054012
DOI: 10.1097/ANC.0000000000000890 -
Advances in Skin & Wound Care Aug 2020To provide information about the latest evidence-based practice related to pressure injuries (PIs). (Review)
Review
GENERAL PURPOSE
To provide information about the latest evidence-based practice related to pressure injuries (PIs).
TARGET AUDIENCE
This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.
LEARNING OBJECTIVES/OUTCOMES
After participating in this educational activity, the participant should be better able to:1. Identify risk factors and prevention strategies for PI.2. Explain issues related to the treatment of PI.
ABSTRACT
The literature on pressure injuries continues to expand at a rapid rate, and keeping up to date with the current knowledge base is challenging. This summary describes six important new articles published in 2018 or 2019 about pressure injury pathophysiology, prevention, treatment, and epidemiology. For each article, a description of the results is provided, and then a comment about the significance of the results is offered. The new knowledge contained in this review should impact how clinicians incorporate the latest evidence-based practice for pressure injuries.
Topics: Clinical Competence; Humans; Pressure Ulcer; Risk Assessment; Skin Care; Wound Healing; Wounds and Injuries
PubMed: 32697473
DOI: 10.1097/01.ASW.0000668552.48758.1c -
British Journal of Nursing (Mark Allen... Aug 2019The skin is the largest and one of the most important organs of the body and as such it is essential that skin integrity is maintained to preserve normal body functions... (Review)
Review
The skin is the largest and one of the most important organs of the body and as such it is essential that skin integrity is maintained to preserve normal body functions as much as possible at all times. Health professionals must endeavour to minimise any pain and trauma likely to be encountered by their patients through the use of a variety of medical products and devices that are designed to adhere to the skin, especially as the use of dermatological and wound-management products in particular, that incorporate adhesives to help keep them secure and in place, has grown in line with the increasingly ageing population and changing demographics throughout the UK. This article reviews the literature related to the causes of medical-adhesive-related skin injuries (MARSIs) and the reported patient effects, in particular pain and skin trauma and highlight some 'at-risk' patient groups and potential actions to minimise risk. A sterile silicone medical adhesive remover-Appeel Sterile-is introduced and the clinical benefits highlighted through the discussion of clinical evidence and case studies undertaken on a range of patients with varied aetiologies.
Topics: Humans; Pain; Skin; Skin Care; Tissue Adhesives; Vulnerable Populations; Wounds and Injuries
PubMed: 31393764
DOI: 10.12968/bjon.2019.28.15.S26 -
Journal of Drugs in Dermatology : JDD Sep 2023Onjectives: To evaluate the long-term efficacy and tolerance of an anti-aging daily serum (AADS) when used twice-daily over 12 weeks by women with moderate skin fatigue... (Randomized Controlled Trial)
Randomized Controlled Trial
Onjectives: To evaluate the long-term efficacy and tolerance of an anti-aging daily serum (AADS) when used twice-daily over 12 weeks by women with moderate skin fatigue and overall photodamage. The treatment targeted rejuvenation and prejuvenation of the facial skin. Method: This was an institutional review board (IRB)-approved, randomized, single-center, double-blinded, vehicle-controlled (VC) study involving healthy subjects. Seventy female subjects were recruited aged 30 to 60 years old, Fitzpatrick skin types I to VI, with moderate overall photodamage, facial skin dullness, and skin firmness. Subjects underwent a 1-week washout period with a skincare regimen consisting of a cleanser, moisturizer, and sunscreen. Subjects were randomized to apply the AADS or VC to their face including upper eyelid, twice-daily for 12 weeks. Long-term efficacy and tolerance, self-assessment questionnaire, and VISIA® clinical photography were performed at baseline, weeks 4, 8, and 12. Results: Statistically significant improvements in live, clinically graded efficacy parameters were demonstrated at post-baseline timepoints. Facial skin firmness, radiance, and roughness showed the most significant improvements at week 12. Analysis between treatments, in both live and photo-graded parameters, demonstrated merit of the AADS. VISIA® analysis further substantiated the efficacy of the AADS vs the VC. The AADS was well tolerated by clinical scoring and rating by subjects. Conclusion: The AADS is effective in improving skin fatigue and overall photodamage after 12 weeks of twice-daily application compared with the VC. The AADS is a possible skincare solution for patients seeking a serum with skin rejuvenation and prejuvenation benefits. Citation: Reid L, Palm MD, Kononov T, et al. Long-term efficacy and tolerability of a daily serum for rejuvenation and prejuvenation of facial skin. J Drugs Dermatol. 2023;22(9):917-924. doi:10.36849/JDD.7393.
Topics: Adult; Female; Humans; Middle Aged; Aging; Fatigue; Rejuvenation; Skin; Skin Care
PubMed: 37683064
DOI: 10.36849/JDD.7393 -
British Journal of Nursing (Mark Allen... Nov 2020Holistic wound assessment focusing on patients' physical and mental wellbeing is essential for effective wound treatment and management and ensuring quality patient...
Holistic wound assessment focusing on patients' physical and mental wellbeing is essential for effective wound treatment and management and ensuring quality patient care. Thorough, accurate and regular assessment can optimise wound healing and enhance patients' quality of life. This article discusses the stages of wound healing and some of the complications of wound healing, which inform an assessment.
Topics: Adult; Humans; Quality of Life; Skin Care; Treatment Outcome; Wound Healing; Wounds and Injuries
PubMed: 33180604
DOI: 10.12968/bjon.2020.29.20.S18 -
In Vivo (Athens, Greece) 2023Radiation therapy (RT) for head and neck cancer may cause severe radiation dermatitis (RD) resulting in RT interruption and affecting disease control. A few studies...
BACKGROUND/AIM
Radiation therapy (RT) for head and neck cancer may cause severe radiation dermatitis (RD) resulting in RT interruption and affecting disease control. A few studies address skin moisture changes during RT for head and neck cancer. The purpose of this study was to explore the effect of moisturized skin care (MSC) on severity of RD.
PATIENTS AND METHODS
The study includes newly diagnosed head and neck cancer patients undergoing RT. Participants were divided into MSC group and routine skin care (RSC) group based on patient's preferred decision. Skin moisture in the four quadrants of the neck was measured weekly before and after RT. RD was assessed with the Radiation Induced Skin Reaction Assessment Scale (RISRAS) and the Radiation Therapy Oncology Group (RTOG) acute skin toxicity grading criteria.
RESULTS
A total of 54 patients were enrolled, of which 49 patients were suitable for the statistical analysis. There was a statistically significant difference in the RISRAS total score since the 5 week after RT between the groups. The severity of RD was less (B=0.814, p=0.021) and the onset was later (B=-0.384, p=0.006) in the MSC group when compared to the RSC group. Skin moisture decreased with cumulative radiation dose. In the upper neck, the MSC group had a slower rate of skin moisture decrease compared to the RSC group (right upper neck: B=0.935, p=0.007; left upper neck: B=0.93, p=0.018).
CONCLUSION
MSC can effectively reduce the severity and delay the onset of RD, while slows down skin moisture decrease during RT.
Topics: Humans; Radiodermatitis; Head and Neck Neoplasms; Skin Care
PubMed: 37905662
DOI: 10.21873/invivo.13389 -
Advances in Skin & Wound Care Dec 2019
Review
Topics: Allergens; Dermatitis, Allergic Contact; Female; Humans; Male; Risk Assessment; Severity of Illness Index; Skin Care; Skin Tests; Treatment Outcome; Wound Healing; Wounds and Injuries
PubMed: 31764139
DOI: 10.1097/01.ASW.0000612432.75874.58 -
International Journal of Cosmetic... Apr 2024Emotions play an important role in consumers' perception of a sensory experience. The objective of this work was to investigate the ability of basic skin care formulas...
OBJECTIVE
Emotions play an important role in consumers' perception of a sensory experience. The objective of this work was to investigate the ability of basic skin care formulas (i.e. without interference of odour, colour and packaging) and pillar ingredients (i.e. emollients and rheology modifiers) to elicit emotions. Another objective was to track, as claimed by neurocosmetics, the possible effect of formulas to trigger emotions from their direct biochemical effects on the skin.
METHODS
Standard methodologies were mobilized, combining subjective and behavioural parameters (i.e. verbatim, prosody and gesture). Sense and Story methodology based on a collection of metaphoric verbatim was conducted after an induction phase. In addition, an experimental electrophysiological real-time visualization method was tried as a first experience in cosmetics. Finally, the ability of formulations with emotional benefits to modulate the release of neuropeptides by sensory neurons was evaluated on a 3D human model (epidermis co-cultured with sensory neurons).
RESULTS
Skin care formulas were shown to play a role in emotional potential and the types of emotion generated, while changing one ingredient mostly acted on the intensity of the emotions. Verbatim provided contrasted answers depending on the protocol, highlighting the interest of non-verbal approaches to detect subtle effects. The in vitro model substantiated physiological effects of skin care formulas with emotional potential on human skin sensory neuron activity.
CONCLUSION
Emotions were impacted by the change in ingredients and were better captured through non-verbal methods.
Topics: Humans; Skin; Skin Care; Cosmetics; Epidermis; Research Design
PubMed: 37914390
DOI: 10.1111/ics.12928 -
Journal of Drugs in Dermatology : JDD Sep 2023Defensins recruit leucine-rich repeat-containing G protein-coupled receptor 6 positive (Lgr6+) stem cells which ultimately regenerate new basal stem cells, healthy...
BACKGROUND
Defensins recruit leucine-rich repeat-containing G protein-coupled receptor 6 positive (Lgr6+) stem cells which ultimately regenerate new basal stem cells, healthy keratinocytes, and nascent hair follicles. Thus, defensins are an exciting, novel therapy for the reversal of skin aging.
METHODS
This is a multicenter, prospective, open-label clinical trial. Twenty healthy subjects, aged 45-80, with Fitzpatrick skin types II-IV were enrolled in the study. A skin care regimen containing alpha-defensin 5 and beta-defensin 3 were applied to the face twice daily for 12 weeks. This skin care regimen contains a greater percentage of defensins than that already studied.7 All participants underwent imaging at baseline, day 30, day 60, and day 90. Primary endpoints included investigator scoring on the Fitzpatrick-Goldman wrinkle scale and percent improvement in periorbital wrinkles, laxity, pigmentation, erythema, texture, and radiance. Secondary endpoints were investigator Global Aesthetic Improvement Score (GAIS), subject GAIS, and investigator assessment of tolerability. A final subject questionnaire was completed on day 90. Results: Based on the Fitzpatrick-Goldman wrinkle scale, a statistically significant improvement was noted in both wrinkling and elastosis from baseline to day 90. 30% of subjects were rated as much improved and 50% of subjects were rated as improved on the physician GAIS at the 90 day follow up. Improvements were noted in all aspects of skin quality including wrinkles, laxity, dyschromia, erythema, texture, and radiance. Conclusion: The enhanced formula containing increased concentrations of alpha-defensin 5 and beta-defensin 3 is a safe and efficacious topical therapy for the treatment of periorbital rhytids.
CITATION
Hartman N, Loyal J, Taub A, et al. Clinical trial of alpha and beta defensin skin care regimen for improvement of periocular wrinkles. J Drugs Dermatol. 2023;22(9):874-880. doi:10.36849/JDD.7184.
Topics: Humans; beta-Defensins; Prospective Studies; Skin Aging; alpha-Defensins; Skin Care; Pigmentation Disorders
PubMed: 37683059
DOI: 10.36849/JDD.7184 -
International Journal of Nursing Studies Sep 2023
Topics: Humans; Skin Care; Nursing Staff, Hospital; Nurses
PubMed: 37348391
DOI: 10.1016/j.ijnurstu.2023.104534