-
Scientific Reports Mar 2023Batik, a resist-dyeing technique to decorate a special cotton fabric, has been practiced for centuries in Indonesia. Unfortunately, as an informal enterprise, batik...
Batik, a resist-dyeing technique to decorate a special cotton fabric, has been practiced for centuries in Indonesia. Unfortunately, as an informal enterprise, batik industry activities lack work safety and health regulations. This study aimed to identify potential health hazards, including inventorying the chemicals to which the workers are exposed, the PPE profile, and investigating the prevalence of occupational skin diseases (OSD) in the batik industry. A cross-sectional study and an inventory of exposure to the chemicals were done in traditional batik workplaces in 5 districts in Yogyakarta province, Indonesia. The chemicals were classified as potential sensitizers/irritants, and the workers were examined and interviewed using the Nordic Occupational Skin Questionnaire-2002/LONG. Of 222 traditional batik workers, OSD were diagnosed in 61 (27.5%) workers, with occupational contact dermatitis was the most common OSD encountered (n = 23/61; 37.7%) (allergic contact dermatitis n = 7/23; irritant contact dermatitis n = 16/23). A smaller portion of other OSD was also encountered including callus, miliaria, and nail disorder (9%, 6.3%, and 5.9%, respectively). During each step of the traditional batik manufacturing process, the workers are exposed to substances that act as irritants and/or as potential contact allergens. However, only one-fourth of the workers used PPE regularly, particularly during the coloring process and wax removal (wet processes). Traditional batik manufacturing process exposes the worker to various physical and chemical hazards, resulting in a high prevalence of occupational skin diseases, especially contact dermatitis among the employees.
Topics: Humans; Indonesia; Irritants; Prevalence; Cross-Sectional Studies; Dermatitis, Allergic Contact; Dermatitis, Occupational; Dermatitis, Irritant; Occupational Exposure
PubMed: 36997563
DOI: 10.1038/s41598-022-17890-w -
Acta Bio-medica : Atenei Parmensis Nov 2020Skin disorders are very common in children. Wide spectrum of skin disorders is seen among children. The spectrum of skin disorders seen in children vary from region to...
BACKGROUND
Skin disorders are very common in children. Wide spectrum of skin disorders is seen among children. The spectrum of skin disorders seen in children vary from region to region.
AIM OF THE WORK
The study is aimed to determine the pattern of skin disorders among children in Pediatric dermatology clinic of Murtala Muhammad Specialist Hospital, Kano, Nigeria. Methods: It was a descriptive cross-sectional study. Subjects were consecutively recruited. Using a semi-structured questionnaire, demographic history of the subjects and history of skin disorders were obtained from all the subjects and detailed physical examination was carried out with particular emphasis on skin lesion examination after obtaining an informed consent. Ethical clearance was obtained from Ethical committee of the hospital. Data obtained was analyzed using SPSS version 24.
RESULTS
A total of 338 subjects were recruited. One hundred and seventy-three (51.2%) were males and 165 (48.8%) were females. There were 35 specific types of skin disorders observed. Infections and infestations were the commonest category of skin disorders seen among 47% of the children followed by inflammatory skin disorders observed among 36.9% of the subjects. Tinea capitis was the commonest type of skin disorder observed among 15.5% of the subjects followed by atopic eczema (13.0%). Tinea capitis was significantly commoner among male children aged 6-10 years (p<0.01) and Miliaria was significantly commoner among children aged less than 2years (p=0.04).
CONCLUSION
Wide spectrum of skin disorders was seen among children in this environment and infections and infestations were the commonest category of skin disorders seen.
Topics: Ambulatory Care Facilities; Child; Child, Preschool; Cross-Sectional Studies; Female; Hospitals; Humans; Male; Nigeria; Skin Diseases
PubMed: 33525278
DOI: 10.23750/abm.v91i4.8727 -
Journal of Family Medicine and Primary... Jun 2022Pediatric skin disorders are different from the adult type in their presentations, types, treatment and prognosis. Their presentation varies from place to place.
INTRODUCTION
Pediatric skin disorders are different from the adult type in their presentations, types, treatment and prognosis. Their presentation varies from place to place.
AIM
To study the different clinical pattern and seasonal variation of dermatoses in children attending a multispecialty hospital in Uttar Pradesh.
MATERIALS AND METHODS
This study was conducted among 640 children who attended the OPD of multispecialty hospital over a period of one year. All children up to 10 years of age with cutaneous presentations were included in the study.
RESULTS
Study showed that there was a male preponderance among the study participants. According to the age group, school-aged children (6-10 years) constituted the highest percentage (53%) followed by toddlers or pre-school children (41%). The most common skin conditions were infections (47%) followed by eczematous group (31%) of disorders. Among the infections, the most common infections were fungal - 35.64% (107) followed by parasitic infection (31%), viral infections (20%) and then bacterial infections (12.5%). Out of total eczematous dermatoses, Atopic dermatosis was maximum in number (61; 30%). This was followed by pityriasis Alba (47; 23.15%), and acute eczemas (32; 15.76%). Third most common dermatosis was Appendageal disorder (33; 5.15%). It included 15 cases of miliaria i.e. approximately 45.45%. Seventeen (2.65%) children reported for treatment of different kind of nevi. Pigmentary disorders were seen in 16 cases (2.5%). Three nutritional disorders were also seen. Season wise, most of the cases were seen in monsoons (June to October).
CONCLUSIONS
Dermatoses is very common in children in the western region of Uttar Pradesh. The largest group was formed by infections followed by eczemas. Few cases increased in number depending upon the weather like fungal and bacterial infections, acne, miliaria in summers and xerosis, scabies in winters. This variation strongly suggests that weather has a very important role. Thus various measures including health education programs to be initiated to control and prevent the sudden spread of the diseases. Thus, Primary care providers and family physicians being the first responders should always keep in mind the seasonal variations while dealing with dermatosis in children.
PubMed: 36119157
DOI: 10.4103/jfmpc.jfmpc_1964_21 -
Indian Journal of Dermatology 2021Skin is the largest organ of the human body, and one of the most sensitive indicators of a child's general health. Skin disorders, especially among children, may cause...
BACKGROUND
Skin is the largest organ of the human body, and one of the most sensitive indicators of a child's general health. Skin disorders, especially among children, may cause an additional emotional and psychological stress to the patients and their family.
AIM
We aim to compare the extent to which various skin diseases affect the quality of life among the pediatric age group (5-12 years) based on Children's Dermatology Life Quality Index (CDLQI) scores.
MATERIALS AND METHODS
A cross-sectional study of 453 patients who attended skin clinic at a regional hospital in Northern India between November 2015 and May 2017. The study consists of questions regarding dermatoses. Patients were evaluated using a standardized pro forma and a CDLQI questionnaire. The diseases with abnormal high proportions were evaluated by the control chart technique.
RESULTS
Out of a total of 453 pediatric patients identified for dermatoses, the average quality of life based on the CDLQI score did not show significant variation across different seasons ( < 0.522). Although the type of skin disorders ( < 0.001) had a significant effect on the quality of life of the children. Based on the CDLQI scores, following diseases have a significant adverse effect on quality of life of the patients - miliaria, atopic dermatitis, scabies, impetigo, and pediculosis capitis.
CONCLUSION
Our study has shown that skin diseases, irrespective of the type, adversely impair the quality of life of the child and in turn the family, therefore, calls for an enhanced level of compassion and care.
PubMed: 35283507
DOI: 10.4103/ijd.ijd_807_20 -
Cureus May 2022Miliaria is a self-limiting cutaneous disease that may develop from skin exposure to humid climates, occlusion, or raised temperatures, forming groups of 1-3-mm-sized...
Miliaria is a self-limiting cutaneous disease that may develop from skin exposure to humid climates, occlusion, or raised temperatures, forming groups of 1-3-mm-sized sweat-filled vesicles in the epidermis due to obstruction of the eccrine sweat duct. Here, we describe the first case of extensive bullous miliaria reported in a 47-year-old female with no comorbidities or significant medical history.
PubMed: 35637920
DOI: 10.7759/cureus.25323 -
JAAD Case Reports May 2021
PubMed: 33898685
DOI: 10.1016/j.jdcr.2021.02.003 -
Molecular & Cellular Proteomics : MCP Jul 2019The eccrine sweat gland is an exocrine gland that is involved in the secretion of sweat for control of temperature. Malfunction of the sweat glands can result in...
The eccrine sweat gland is an exocrine gland that is involved in the secretion of sweat for control of temperature. Malfunction of the sweat glands can result in disorders such as miliaria, hyperhidrosis and bromhidrosis. Understanding the transcriptome and proteome of sweat glands is important for understanding their physiology and role in diseases. However, no systematic transcriptome or proteome analysis of sweat glands has yet been reported. Here, we isolated eccrine sweat glands from human skin by microdissection and performed RNA-seq and proteome analysis. In total, ∼138,000 transcripts and ∼6,100 proteins were identified. Comparison of the RNA-seq data of eccrine sweat glands to other human tissues revealed the closest resemblance to the cortex region of kidneys. The proteome data showed enrichment of proteins involved in secretion, reabsorption, and wound healing. Importantly, protein level identification of the calcium ion channel TRPV4 suggests the importance of eccrine sweat glands in re-epithelialization of wounds and prevention of dehydration. We also identified 2 previously missing proteins from our analysis. Using a proteogenomic approach, we identified 7 peptides from 5 novel genes, which we validated using synthetic peptides. Most of the novel proteins were from short open reading frames (sORFs) suggesting that many sORFs still remain to be annotated in the human genome. This study presents the first integrated analysis of the transcriptome and proteome of the human eccrine sweat gland and would become a valuable resource for studying sweat glands in physiology and disease.
Topics: Amino Acid Sequence; Eccrine Glands; Exons; Humans; Open Reading Frames; Proteome; Proteomics; Pseudogenes; RNA; Transcriptome
PubMed: 30979791
DOI: 10.1074/mcp.RA118.001101 -
JAAD Case Reports Jun 2024
PubMed: 38783929
DOI: 10.1016/j.jdcr.2024.03.014 -
Actas Dermo-sifiliograficas Oct 2020
Topics: Child; Fox-Fordyce Disease; Humans
PubMed: 32563546
DOI: 10.1016/j.ad.2019.03.016 -
International Journal of Women's... Oct 2022
PubMed: 35966823
DOI: 10.1097/JW9.0000000000000039