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Journal of Neurology, Neurosurgery, and... Dec 1980
Topics: Adie Syndrome; Humans; Reflex, Abnormal
PubMed: 7217964
DOI: 10.1136/jnnp.43.12.1147-a -
British Medical Journal Feb 1969
Topics: Adie Syndrome; Adolescent; Adult; Female; Humans; Male; Muscle Contraction; Paralysis; Parasympathetic Nervous System; Pupil; Reflex, Stretch
PubMed: 5762637
DOI: No ID Found -
Journal Francais D'ophtalmologie Oct 2022
Topics: Humans; Tonic Pupil; Uveomeningoencephalitic Syndrome
PubMed: 35690526
DOI: 10.1016/j.jfo.2022.01.019 -
Neurology Aug 1967
Review
Topics: Adie Syndrome; Adult; Anisocoria; Heat Stress Disorders; Humans; Hypohidrosis; Male; Methacholine Chloride; Reflex, Abnormal; White People
PubMed: 15088536
DOI: 10.1212/wnl.17.8.763 -
Indian Journal of Ophthalmology Mar 2021With increasing experience, it has been suggested that the SARS-CoV-2 virus has a neurotropic effect. Here, we present a case of a tonic pupil who developed after...
With increasing experience, it has been suggested that the SARS-CoV-2 virus has a neurotropic effect. Here, we present a case of a tonic pupil who developed after COVID-19 infection. A 36-year-old woman presented with progressive photophobia and blurred vision. On neurological examination, loss of deep tendon reflexes accompanying a tonic pupil was detected and brain MR imaging was normal. With this case, we aimed to describe a rare pattern of neurological involvement caused by the possible SARS-CoV-2 virus.
Topics: Adie Syndrome; Adult; COVID-19; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; RNA, Viral; SARS-CoV-2
PubMed: 33595525
DOI: 10.4103/ijo.IJO_3589_20 -
Proceedings of the Royal Society of... Jan 1942
PubMed: 19992459
DOI: No ID Found -
Clinical & Experimental Ophthalmology Nov 2014William John Adie was an Australian neurologist in the early 20th century responsible for extensively describing the tonically dilated pupil associated with absent deep...
William John Adie was an Australian neurologist in the early 20th century responsible for extensively describing the tonically dilated pupil associated with absent deep tendon reflexes - both features of a syndrome that now bears his name. In addition to other neurological syndromes, he was also significant in delineating narcolepsy through his clinical essays and case series. His ophthalmic and neurologic contributions have served the test of time and played an important role in the modern understanding of Adie syndrome and narcolepsy. This report reviews Adie's medical contributions, extensive descriptions of Adie syndrome, and provides a brief biographical account of his life.
Topics: Adie Syndrome; Australia; History, 19th Century; History, 20th Century; Humans; Ophthalmology; Tonic Pupil
PubMed: 24533698
DOI: 10.1111/ceo.12301 -
Transactions of the American... 1977Adie's syndrome is a disease of unknown etiology. We known where the damage is, and which nerves are involved. We even know something of how the nerves react after the... (Comparative Study)
Comparative Study
Adie's syndrome is a disease of unknown etiology. We known where the damage is, and which nerves are involved. We even know something of how the nerves react after the damage is done, but we don't known what causes the primary injury. The first step in working a jigsaw puzzle is to getall of the pieces right side up and take a good look at them. Some of the jigsaw pieces handled in this paper are listed below. Some of them are new observations; many of them are old concepts, partly modified and partly made secure by new facts. 1. Not all "tonic pupils" are due to "Adie's syndrome"; some are due to local injury and some to a generalized peripheral neuropathy (Table II). 2. All patients should have serologic tests for shyphilis. In this series one in six had positive serology. 3. The incidence of Adie's syndrome in Iowa in the early 1970's was approximately 4.7 per 100,000 population per year. 4. The prevalence of Adie's syndrome, therefore, was approximately 2 per 1000. 5. The mean age of onset of Adie's syndrome was about 32.2 years (Figure 1A). 6. The sex ratio was 2.6 females to each male. 7. Right eyes and left eyes were involved at approximately the same rate (Figure 2). 8. The incidence of second eye involvement in unilateral cases was about 4% per year during the first decade of the disease (Figure 18). 9. If this rate of second eye involvement (4% per year) persists during subsequent decades, then most Adie's pupils will eventually become bilateral. 10. The incidence of Adie's syndrome in a largely caucasian patient group is independent of iris color (Figure 4). 11. Only 10% of patients with Adie's syndrome had completely normal muscle stretch reflexes. 12. The muscle stretch reflexes in the arms were just as frequently imparied as those in th elegs, but the degree of impariment tended to be more severe in the ankles and triceps. 13. When there was any light reaction remaining in an Adie's pupil, a segmental paralysis of the sphincter muscle could be seen. 14. The near reaction of the pupil was often segmental and frequently involved segments which did not respond to light. 15. The segmental paralysis to light was randomly distributed around the sphincter (Figure 6B). 16. There was some tendency for the sphincter palsy to gradually become worse. This progression was also random (Figure 8). 17. Almost all patients with Adie's syndrome had an accommodative paresis at the time of onset. 18. Reading glasses given to a patient with a fresh Adie's pupil were soon discarded as accommodation recovered (Figure 9). 19. Accomodative effort induced an astigmatism in about half of the eyes with Adie's--presumably the result of a segmental palsy of the ciliary muscle. 20. Tonicity of accommodation was present in about 1/2 of the eyes with Adie's, making it difficut for the patient to maintain a steady level of ciliary muscle tone. 21. An occasional patient complained of brow ache from ciliary spasm with near work. 22. In most patients with Adie's syndrome the ciliary muscle was supersensitive to pilocarpine 0...
Topics: Accommodation, Ocular; Adie Syndrome; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Eye Color; Female; Functional Laterality; Humans; Iris; Male; Middle Aged; Miotics; Mydriatics; Pupil; Reflex, Abnormal; Reflex, Pupillary; Sex Factors
PubMed: 613531
DOI: No ID Found -
Acta Bio-medica : Atenei Parmensis Nov 2021The literature describes that the renowned artwork of the genius of human anatomy, Leonardo da Vinci (1452-1519), known as Mona Lisa (1503-1506), is among one of the...
The literature describes that the renowned artwork of the genius of human anatomy, Leonardo da Vinci (1452-1519), known as Mona Lisa (1503-1506), is among one of the most enigmatic artworks in the History of Art. In this context, many details inserted on the composition of this artwork, including those related to Mona Lisa physical aspects' (anatomy) are controversial. The few known descriptions that provide some thorough indications about the woman who served as the model for this work, were written by Giorgio Vasari (1511-1574) in 1550. According to Vasari, the Mona Lisa is a portrait of Lisa del Giocondo (1479-1542) and although he has given a detailed description concerning Lisa's physical characteristics, some are not fully understood so far. In this context, the unequal size of her pupils stands out, a clinical condition known as anisocoria. On this detail, this Letter presents unprecedented pieces of evidence that the anisocoria represented in Mona Lisa may be an indicator that Lisa del Giocondo had a neurological disorder known as Holmes-Adie Syndrome, which could have been caused by an endocrine disruption of the thyroid hormones. Thus, the pieces of information presented on this Letter are essential for further studies once, through them, it is possible to know more about the physical characteristics and also about the probable health condition of the renowned character of one of the most famous artworks of history.
Topics: Adie Syndrome; Famous Persons; Female; Humans; Male
PubMed: 34738587
DOI: 10.23750/abm.v92i5.10355 -
Wiadomosci Lekarskie (Warsaw, Poland :... Dec 1985
Review
Topics: Adie Syndrome; Adult; Arm; Female; Humans; Leg; Male; Reflex, Abnormal; Reflex, Pupillary; Reflex, Stretch
PubMed: 3914139
DOI: No ID Found