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Journal of Neuro-ophthalmology : the... Dec 2011Tonic pupils react poorly to light but constrict during viewing of a near stimulus. Adie's name is typically used in association with tonic pupils, but a review of...
Tonic pupils react poorly to light but constrict during viewing of a near stimulus. Adie's name is typically used in association with tonic pupils, but a review of Adie's articles reveals that he described the syndrome of tonic pupils and absent reflexes and not the pupillary abnormality per se. Therefore, it would be more appropriate to refer to a tonic pupil as simply a "tonic pupil" and leave Adie's name for the syndrome.
Topics: Accommodation, Ocular; Australia; History, 20th Century; Humans; Light; London; Reflex, Pupillary; Tonic Pupil
PubMed: 21597384
DOI: 10.1097/WNO.0b013e318219fbdf -
Neurological Sciences : Official... Mar 2014
Topics: Brain; Female; Humans; Magnetic Resonance Imaging; Morocco; Pilocarpine; Steroids; Tonic Pupil; Uveomeningoencephalitic Syndrome; Young Adult
PubMed: 24162178
DOI: 10.1007/s10072-013-1567-6 -
Italian Journal of Neurological Sciences Oct 1997We here report two cases of Adie's tonic pupil, associated with clinical sensory polyneuropathy and Sjögren's syndrome, in one of whom it actually heralded the onset of...
We here report two cases of Adie's tonic pupil, associated with clinical sensory polyneuropathy and Sjögren's syndrome, in one of whom it actually heralded the onset of the syndrome. Electrophysiology studies indicated absent H reflexes but normal peripheral nerve conductions, thus suggesting an involvement of the dorsal roots or spinal ganglion that would be in line with previously published reports of dorsal ganglionitis as the primary neuropathological lesion in Sjögren's syndrome. We suggest that all cases of tonic pupils should be screened for polyneuropathy and Sjögren's syndrome.
Topics: Adie Syndrome; Autoantibodies; Electrophysiology; Female; H-Reflex; Humans; Male; Middle Aged; Reflex, Pupillary; Sjogren's Syndrome
PubMed: 9412854
DOI: 10.1007/BF02083307 -
Annals of Ophthalmology Feb 1979
Topics: Adie Syndrome; Adult; Aged; Humans; Male
PubMed: 434743
DOI: No ID Found -
Journal of the Royal College of... Oct 1974
Topics: Adie Syndrome; Adolescent; Adult; Age Factors; Aged; Aneurysm; Blepharoptosis; Diabetic Neuropathies; Edema; Exophthalmos; Eye Movements; Female; Fundus Oculi; Hemianopsia; Horner Syndrome; Humans; Male; Middle Aged; Ophthalmoplegia; Optic Atrophy; Optic Neuritis; Scotoma; Sex Factors; Visual Field Tests; Visual Fields
PubMed: 4414794
DOI: No ID Found -
Eye (London, England) 1990Autonomic function was studied in a group of 11 patients with Holmes Adie Syndrome. Autonomic function was assessed by the measurement of cardiovascular reflexes. Heart...
Autonomic function was studied in a group of 11 patients with Holmes Adie Syndrome. Autonomic function was assessed by the measurement of cardiovascular reflexes. Heart rate responses to respiration, valsalva manoeuvre and standing were studied. The change in systolic blood pressure on moving from the lying to the standing position was measured. Abnormalities of parasympathetic function were found in three patients, compared with matched controls. Autonomic dysfunction in Holmes Adie Syndrome may be more widespread than previously suspected.
Topics: Adie Syndrome; Adult; Aged; Aged, 80 and over; Autonomic Nervous System; Blood Pressure; Female; Heart Rate; Humans; Male; Middle Aged; Parasympathetic Nervous System; Posture
PubMed: 2226992
DOI: 10.1038/eye.1990.85 -
Journal of Anesthesia Apr 2015
Topics: Adie Syndrome; Anesthesia, General; Anisocoria; Female; Humans; Middle Aged; Neurologic Examination; Reflex, Pupillary
PubMed: 25138821
DOI: 10.1007/s00540-014-1902-y -
Scientific Reports May 2021We have compared the diagnostic ability of different concentrations of 0.125% and 0.0625% dilute pilocarpine for detecting denervation supersensitivity in unilateral... (Observational Study)
Observational Study
We have compared the diagnostic ability of different concentrations of 0.125% and 0.0625% dilute pilocarpine for detecting denervation supersensitivity in unilateral Adie's tonic pupil. This retrospective, observational, case-control study involved 117 subjects, consisting of 56 patients with unilateral Adie's tonic pupil and 61 controls with other causes of unilateral dilated pupils. Subjects underwent the dilute pilocarpine test with one of the two concentrations, 0.125% or 0.0625%. Pupillary light reflex was recorded with a dynamic pupillometer at baseline and at 30-40 min after instilling one of the two concentrations of dilute pilocarpine. Diagnostic accuracy of two different concentrations of the dilute pilocarpine test, 0.125% group versus 0.0625% group, were compared by area under the receiver operating characteristic curve (AUC). Diagnostic ability of the dilute pilocarpine test for detecting denervation supersensitivity in unilateral Adie's tonic pupil was significantly better in the 0.0625% group than in the 0.125% group (AUC = 0.954 vs. 0.840, respectively, P = 0.047). In the 0.0625% group, the change in maximal pupil diameter of ≥ 0.5 mm after topical pilocarpine instillation showed 100% sensitivity and 82.8% specificity for detecting Adie's tonic pupil. This study confirmed that pupillary constriction with 0.0625% pilocarpine is better than 0.125% pilocarpine for detecting denervation supersensitivity in Adie's tonic pupil. Digital pupillometry is a reliable method for assessing denervation supersensitivity in Adie's tonic pupil.
Topics: Adie Syndrome; Adult; Aged; Case-Control Studies; Female; Humans; Male; Middle Aged; Pilocarpine; Reflex, Pupillary; Retrospective Studies
PubMed: 33980910
DOI: 10.1038/s41598-021-89148-w -
Journal of Neurology, Neurosurgery, and... Oct 1979The pathophysiological mechanisms underlying benign areflexia were studied in six patients with Holmes-Adie syndrome. No impairment of sensory conduction velocity of...
The pathophysiological mechanisms underlying benign areflexia were studied in six patients with Holmes-Adie syndrome. No impairment of sensory conduction velocity of sural nerve was found. A normal tonic vibration reflex was obtained in all patients. H reflex was absent in five patients, but responses like F waves were recorded in three subjects. These findings suggest that muscle spindles are not affected and that spinal motoneurone excitability is normal.
Topics: Adie Syndrome; Adult; Aged; Electrophysiology; Female; Humans; Male; Middle Aged; Motor Neurons; Neural Conduction; Peripheral Nerves; Reflex, Abnormal; Reflex, Monosynaptic; Vibration
PubMed: 512669
DOI: 10.1136/jnnp.42.10.943 -
Zeitschrift Fur Psychotherapie Und... May 1953
Topics: Adie Syndrome; Humans
PubMed: 13103556
DOI: No ID Found