-
Radiology Dec 1994To assess the utility of computed tomography (CT) in the evaluation of suspected bronchogenic carcinoma.
PURPOSE
To assess the utility of computed tomography (CT) in the evaluation of suspected bronchogenic carcinoma.
MATERIALS AND METHODS
CT scans were reviewed of 362 patients who had undergone CT for suspected bronchogenic carcinoma.
RESULTS
CT findings of 275 patients were consistent with bronchogenic carcinoma. Sixty-five tumors were deemed unresectable on the basis of CT findings, 21 were deemed unresectable on the basis of CT findings and poor surgical risk, 26 proved to be benign, six were metastatic disease from an extrathoracic primary tumor, and 157 were potentially resectable bronchogenic carcinoma. Surgical mediastinal nodal sampling enabled documentation of metastases in 60 of 159 patients. According to nodal station, the sensitivity of CT for metastases was 67% for nodes measured in the long axis and 58% for nodes measured in the short axis; specificity was 56% and 86%, respectively.
CONCLUSION
CT can be used to confirm or exclude the presence of bronchogenic carcinoma and to obviate thoracotomy. The specificity of CT is limited, and a histologic diagnosis or follow-up evaluation is necessary. CT has limited value in staging mediastinal lymph nodes.
Topics: Carcinoma, Bronchogenic; Female; Humans; Lung; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed
PubMed: 7972827
DOI: 10.1148/radiology.193.3.7972827 -
The Nurse Practitioner 1981Despite much research and clinical application of various treatment modalities, the five-year survival rate in bronchogenic carcinoma is very poor. With over 90,000 lung... (Review)
Review
Despite much research and clinical application of various treatment modalities, the five-year survival rate in bronchogenic carcinoma is very poor. With over 90,000 lung cancer deaths recorded in 1977, and over 100,000 deaths estimated in 1980, we should emphasize prevention as well as cure in our daily patient contacts. Patients particularly at high risk are (a) men over 45 years of age with more than 10 pack-years of smoking, (b) patients (men and women) with chronic cough, recent pneumonia, or hemoptysis. (c) Patients with a stable solitary nodule, (d) patients with occupational exposure. Hopefully, with prevention, early diagnosis, and improved treatment, our role in management of the lung cancer patient will be easier. Management of the patient with bronchogenic carcinoma will follow in the second part of this article.
Topics: Adult; Aged; Carcinoma, Bronchogenic; Female; Humans; Lung Neoplasms; Male; Middle Aged; Risk
PubMed: 7007929
DOI: No ID Found -
Texas Medicine Dec 1967
Review
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Cyclophosphamide; Female; Humans; Hydrazines; Male; Methotrexate; Middle Aged
PubMed: 4867418
DOI: No ID Found -
Journal of the National Medical... May 1970
Topics: Age Factors; Aged; Black People; Carcinoma, Bronchogenic; Humans; Lung Neoplasms; Male; Middle Aged; Smoking; White People
PubMed: 5419532
DOI: No ID Found -
Vnitrni Lekarstvi Aug 2001Bronchogenic carcinoma is in the Czech Republic the most frequent malignant tumour in males. For practice the classification into non-small cell bronchogenic carcinoma... (Review)
Review
Bronchogenic carcinoma is in the Czech Republic the most frequent malignant tumour in males. For practice the classification into non-small cell bronchogenic carcinoma (NSCLC) and small cell bronchogenic carcinoma (SCLC) is most useful. Views on chemotherapy of NSCLC were before 1980 rather pessimistic. In untreated patients with advanced NSCLC the median survival is 6 months and one-year survival in 10 %. In the nineties, due to the introduction of cytostatics of the IIIrd generation into treatment of NSCLC, the median survival was prolonged to 10 - 12 months and one-year survival is reported in 40 - 50 % patients. The importance of chemotherapy in SCLC was never doubted. By concurrent chemotherapy and radiotherapy the total period of treatment of patients with SCLC was reduced and the percentage of objective responses increased. Introduction of cytostatics of the third generation is important in particular in treatment of line II SCLC. Basic prognostic factors of successful chemotherapy in patients with bronchogenic carcinoma are the stage of the disease, body weight loss, presence of paraneoplastic symptoms, immune state and clinical and sociodemographic characteristics.
Topics: Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Humans; Lung Neoplasms; Prognosis
PubMed: 15633398
DOI: No ID Found -
British Journal of Hospital MedicineBronchogenic carcinoma remains the commonest fatal malignancy worldwide. In this paper we discuss the various imaging modalities available to aid diagnosis and staging,... (Review)
Review
Bronchogenic carcinoma remains the commonest fatal malignancy worldwide. In this paper we discuss the various imaging modalities available to aid diagnosis and staging, presenting these techniques in a clinical sequence. We also consider some of their limitations.
Topics: Bone Neoplasms; Carcinoma, Bronchogenic; Humans; Lung Neoplasms; Neoplasm Staging; Radiography, Thoracic; Radionuclide Imaging; Tomography, X-Ray Computed; Ultrasonography
PubMed: 8431725
DOI: No ID Found -
Archivos de Bronconeumologia Nov 2007To describe the clinical characteristics and survival of patients diagnosed with bronchogenic carcinoma during the years 2000 and 2001 in a tertiary level hospital.
OBJECTIVE
To describe the clinical characteristics and survival of patients diagnosed with bronchogenic carcinoma during the years 2000 and 2001 in a tertiary level hospital.
PATIENTS AND METHODS
Data were collected from our hospital's tumor registry and validated with independent sources. Of all the patients diagnosed with or treated for bronchogenic carcinoma in our hospital, only those from our health care area were selected.
RESULTS
During the 2-year study period, 482 patients were diagnosed. Of those, 91% were men. The mean (SD) age was 66.6 (9.65) years. Large cell carcinomas accounted for 29.4% of cases. Of all the cases of bronchogenic carcinoma, 41.3% were diagnosed in stage IV. Thirty percent of non-small cell carcinomas were classified as stage I, compared to 6% of small cell carcinomas (P< .001). The most frequent treatment was chemotherapy (42.1%) and 20% of patients underwent surgery. The overall 5-year survival rate was 13% (95% confidence interval [CI], 10%-16%), while survival was significantly lower in patients aged 68 years or older (95% CI, 3%-15%; P< .001) and in patients with small cell carcinoma (0%, P< .01).
CONCLUSIONS
Our recent experience (2000-2001) confirmed the advanced age of patients with bronchogenic carcinoma, the frequency of diagnosis in advanced stages of the disease (41% in stage IV), and the low overall 5-year survival rate (13%).
Topics: Aged; Carcinoma, Bronchogenic; Cross-Sectional Studies; Female; Humans; Lung Neoplasms; Male; Retrospective Studies; Survival Rate; Time Factors
PubMed: 17983542
DOI: 10.1016/s1579-2129(07)60135-9 -
Chest Apr 1971
Topics: Carcinoma, Bronchogenic; England; Humans; Iceland; Lung Neoplasms; Male; Middle Aged; Smoking; United States
PubMed: 5551578
DOI: 10.1378/chest.59.4.358 -
The Journal of the American Osteopathic... Sep 1971
Topics: Adult; Carcinoma, Bronchogenic; Hemoptysis; Humans; Lung Neoplasms; Male; Pneumonectomy; Smoking
PubMed: 5209266
DOI: No ID Found -
Journal of Cancer Research and... 2009This study was undertaken to explore the clinicopathological profile of bronchogenic carcinoma in young patients. (Comparative Study)
Comparative Study
OBJECTIVE
This study was undertaken to explore the clinicopathological profile of bronchogenic carcinoma in young patients.
MATERIALS AND METHODS
The present study was conducted on 799 consecutive histopathologically proven cases of bronchogenic carcinoma that were referred from different parts of Uttar Pradesh.
RESULTS
Out of 799 patients, 73 patients (9.1%; 59 males and 14 females) were < or = 40 years of age and were classified as 'young' patients. The mean ages of the subjects in the younger and older patient groups were 36 and 58 years, respectively. Among the older patients, 590 (81.3%) were smokers, and there were 53 (72.6%) smokers among the younger patients. Squamous cell carcinoma was the commonest histological subtype in both the groups, but squamous cell carcinoma was more frequently diagnosed in older patients than in younger patients.
CONCLUSION
This study suggests that, regardless of age or sex, lung cancer must be ruled out in all patients who have persistent signs of pulmonary disease and a history of heavy smoking.
Topics: Adult; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Smoking
PubMed: 19293486
DOI: 10.4103/0973-1482.44296