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Canadian Medical Association Journal Mar 1952
Topics: Carcinoma, Bronchogenic; Humans; Lung Neoplasms
PubMed: 14905385
DOI: No ID Found -
Canadian Medical Association Journal Nov 1952
Topics: Carcinoma, Bronchogenic; Humans; Lung Neoplasms
PubMed: 13009585
DOI: No ID Found -
Jornal Brasileiro de Pneumologia :... 2010To analyze the association between paracoccidioidomycosis (Pcm) and cancer in a series of 25 cases and to review the literature on this topic. (Review)
Review
OBJECTIVE
To analyze the association between paracoccidioidomycosis (Pcm) and cancer in a series of 25 cases and to review the literature on this topic.
METHODS
A retrospective review of 25 cases diagnosed with Pcm and cancer, retrieved from a series of 808 consecutive adult patients diagnosed with Pcm based on tests conducted in the Mycology Laboratory of the Santa Casa Complexo Hospitalar, in the city of Porto Alegre, Brazil, between 1972 and 2007. The diagnosis of Pcm was confirmed by means of direct microscopic examination, histopathological examination or immunodiffusion test. All cancer cases were confirmed by histopathological or cytopathological examination.
RESULTS
Respiratory symptoms were the principal complaints of the patients evaluated. Pulmonary involvement predominated, followed by skin and lymph node involvement. The most prevalent tumor was bronchial carcinoma, in 15 patients, followed by other types of carcinoma, and 1 patient had Hodgkin's lymphoma. In 16 patients (64%), the site of the Pcm was the same as that of the tumor. In most cases, Pcm treatment consisted of the isolated administration of sulfanilamide, sulfamethoxazole-trimethoprim, ketoconazole, itraconazole or amphotericin B. The most common treatment for cancer was surgery, followed by radiotherapy and chemotherapy. Of the 25 patients, 12 were cured of Pcm, and 4 died. In 9 patients, the final outcome was unknown. In the general population of the area under study, the prevalence of lung cancer was significantly higher in smokers with Pcm than in smokers without Pcm (p < 0.001).
CONCLUSIONS
A diagnosis of Pcm appears to increase the risk of lung cancer.
Topics: Adult; Aged; Carcinoma, Bronchogenic; Chi-Square Distribution; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paracoccidioidomycosis; Retrospective Studies; Risk Factors
PubMed: 20625674
DOI: 10.1590/s1806-37132010000300014 -
BMJ Case Reports Oct 2014Intermittent facial swelling is an unusual presentation in the emergency department. The differential diagnosis may range from a variety of causes. Most common...
Intermittent facial swelling is an unusual presentation in the emergency department. The differential diagnosis may range from a variety of causes. Most common differential diagnosis is angio-oedema. However, more serious presentations such as superior venacaval obstruction must not be ignored. This case report presents a patient who was investigated in the hospital for 2 weeks (2 admissions) with intermittent facial swelling. He presented to the emergency department (3rd admission) and was diagnosed to have superior venacaval obstruction secondary to metastatic bronchogenic carcinoma. He underwent emergency endovascular stenting; however, he died within a few weeks.
Topics: Aged, 80 and over; Angioedema; Carcinoma, Bronchogenic; Diagnosis, Differential; Edema; Face; Humans; Lung Neoplasms; Male; Superior Vena Cava Syndrome
PubMed: 25326556
DOI: 10.1136/bcr-2013-202355 -
Journal of the National Medical... Apr 1981Metastases to the small bones of the hands and feet are a rare occurrence. The author reports five cases from his personal experience and reviews the literature....
Metastases to the small bones of the hands and feet are a rare occurrence. The author reports five cases from his personal experience and reviews the literature. Bronchogenic carcinoma appears to be the principal contributor to hand metastases. Although there are approximately 150 reported cases, the true incidence is probably greater due to lack of reporting and lack of attention to the extremities in routine screening procedures. X-ray appearance is uniformly lytic. Local radiotherapy gives palliation.
Topics: Adenocarcinoma; Aged; Bone Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Colonic Neoplasms; Female; Fingers; Foot; Hand; Humans; Lung Neoplasms; Male; Middle Aged; Prostatic Neoplasms
PubMed: 7218364
DOI: No ID Found -
Archives of Pathology & Laboratory... Jan 2004Epithelial-myoepithelial tumor is extremely rare as a pulmonary neoplasm. Only 20 cases have been reported to date, of which 14 were malignant. We report a case of... (Review)
Review
Epithelial-myoepithelial tumor is extremely rare as a pulmonary neoplasm. Only 20 cases have been reported to date, of which 14 were malignant. We report a case of intrabronchial epithelial-myoepithelial carcinoma in a 73-year-old man with a history of heavy smoking. The tumor was well-circumscribed and caused distal airway obstruction. Histologically, the tumor showed glandular and solid architecture. The glands were composed of an inner layer of epithelial cells and an outer layer of myoepithelial cells. The solid areas consisted of spindle-shaped myoepithelial cells. Immunohistochemical staining was positive for p53 and c-Kit (CD117). Focal atypia and increased mitotic activity were present, but no vascular invasion or nodal metastasis was identified.
Topics: Aged; Carcinoma; Carcinoma, Bronchogenic; Humans; Male; Myoepithelioma; Tomography, X-Ray Computed
PubMed: 14692803
DOI: 10.5858/2004-128-92-BEC -
Communications Biology Aug 2021Lung cancer is the main cause of cancer death worldwide, with lung squamous cell carcinoma (LUSC) being the second most frequent subtype. Preclinical LUSC models... (Review)
Review
Lung cancer is the main cause of cancer death worldwide, with lung squamous cell carcinoma (LUSC) being the second most frequent subtype. Preclinical LUSC models recapitulating human disease pathogenesis are key for the development of early intervention approaches and improved therapies. Here, we review advances and challenges in the generation of LUSC models, from 2D and 3D cultures, to murine models. We discuss how molecular profiling of premalignant lesions and invasive LUSC has contributed to the refinement of in vitro and in vivo models, and in turn, how these systems have increased our understanding of LUSC biology and therapeutic vulnerabilities.
Topics: Animals; Carcinoma, Bronchogenic; Embryo, Nonmammalian; Lung Neoplasms; Rats; Rats, Wistar
PubMed: 34354223
DOI: 10.1038/s42003-021-02470-x -
Canadian Medical Association Journal Oct 1953
Topics: Carcinoma, Bronchogenic; Humans; Lung Neoplasms
PubMed: 13094607
DOI: No ID Found -
CA: a Cancer Journal For Clinicians 1979
Topics: Carcinoma, Bronchogenic; Humans; Lung Neoplasms; Neoplasm Staging; Radiography
PubMed: 110406
DOI: 10.3322/canjclin.29.4.233 -
Journal of Cancer Research and... 2009This study was undertaken to explore the clinicopathological profile of bronchogenic carcinoma in young patients. (Comparative Study)
Comparative Study
OBJECTIVE
This study was undertaken to explore the clinicopathological profile of bronchogenic carcinoma in young patients.
MATERIALS AND METHODS
The present study was conducted on 799 consecutive histopathologically proven cases of bronchogenic carcinoma that were referred from different parts of Uttar Pradesh.
RESULTS
Out of 799 patients, 73 patients (9.1%; 59 males and 14 females) were < or = 40 years of age and were classified as 'young' patients. The mean ages of the subjects in the younger and older patient groups were 36 and 58 years, respectively. Among the older patients, 590 (81.3%) were smokers, and there were 53 (72.6%) smokers among the younger patients. Squamous cell carcinoma was the commonest histological subtype in both the groups, but squamous cell carcinoma was more frequently diagnosed in older patients than in younger patients.
CONCLUSION
This study suggests that, regardless of age or sex, lung cancer must be ruled out in all patients who have persistent signs of pulmonary disease and a history of heavy smoking.
Topics: Adult; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Smoking
PubMed: 19293486
DOI: 10.4103/0973-1482.44296