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The New England Journal of Medicine Nov 1977
Topics: Bronchial Spasm; Humans; Phosphodiesterase Inhibitors; Prostaglandin Antagonists; Theophylline
PubMed: 917051
DOI: 10.1056/nejm197711242972118 -
Journal of Perianesthesia Nursing :... Dec 2021Adverse events associated with salvaged blood reinfusion are common, but bronchospasm has been rarely reported, especially in pediatrics. We report the case of a child...
Adverse events associated with salvaged blood reinfusion are common, but bronchospasm has been rarely reported, especially in pediatrics. We report the case of a child undergoing epileptogenic focus resection, who experienced bronchospasm and kidney injury associated with reinfusion of salvaged blood, presumably related to excessive free hemoglobin.
Topics: Arthroplasty, Replacement, Knee; Blood Transfusion, Autologous; Bronchial Spasm; Child; Humans; Kidney; Pediatrics
PubMed: 34736835
DOI: 10.1016/j.jopan.2020.12.014 -
Medical Hypotheses Nov 2015Exercise induced bronchospasm (EIB) affects approximately 10% of normal individuals with higher prevalence rates among children, obese adults, and competitive athletes.... (Review)
Review
Exercise induced bronchospasm (EIB) affects approximately 10% of normal individuals with higher prevalence rates among children, obese adults, and competitive athletes. Although hyperpnea with dry air is the best known cause, the problem is multifactorial with atopy, asthma and chlorine all playing established roles. To date, no clear mechanism has connected musculoskeletal loading with the ensuing pulmonary compromise. This paper reviews evidence that impact-driven pulses in subchondral bone pressure may push osseous fat cells into the local venous sinusoids. The resultant showers of microemboli must then travel to the lung where lysis of membrane phospholipids leads to leukotriene formation with resultant inflammation and bronchial hypersensitivity. Concurrently, the same emboli deliver triglyceride fuels for further physical activity. Thus, pulmonary microemboli derived from osseous fat may resolve the seeming paradox of athletic excellence in persons afflicted with exercise-induced bronchospasm.
Topics: Bronchial Spasm; Exercise; Fats; Humans; Pulmonary Embolism
PubMed: 26328480
DOI: 10.1016/j.mehy.2015.08.014 -
JNMA; Journal of the Nepal Medical... 2019Bronchospasm represents the clinical manifestation of bronchial muscles contraction resulting in reduced alveolar air flow. Non-allergic mechanisms or anaphylaxis...
Bronchospasm represents the clinical manifestation of bronchial muscles contraction resulting in reduced alveolar air flow. Non-allergic mechanisms or anaphylaxis underlie the genesis of perioperative bronchospasm, a potential anaesthetic disaster. Early recognition and treatment are crucial. We report a rare incident of anaphylactic bronchospasm without hypotension during general anaesthesia. Urticaria appeared in chest and abdomen suggesting anaphylaxis. After the event resolved with bronchodilators, surgery continued uneventfully. Vecuronium was the most probable culprit but confirmation was not possible as the patient was lost to follow up. Rarely, perioperative anaphylaxis presents only with bronchospasm that requires prompt attention to avoid adverse outcome. Keywords: allergy; anaphylaxis; bronchial spasm; general anesthesia.
Topics: Adult; Anaphylaxis; Anesthesia, General; Bronchial Spasm; Bronchodilator Agents; Humans; Male; Vecuronium Bromide
PubMed: 32323660
DOI: No ID Found -
European Annals of Allergy and Clinical... Mar 2024
Topics: Humans; Contrast Media; Bronchial Spasm; Iodine Compounds; Drug Hypersensitivity
PubMed: 35850502
DOI: 10.23822/EurAnnACI.1764-1489.262 -
Critical Care Medicine Jun 1987
Topics: Bronchial Spasm; Humans; Hypertension, Pulmonary; Infant, Newborn; Oxygen
PubMed: 3568737
DOI: 10.1097/00003246-198706000-00027 -
Anaesthesia Jul 1985
Topics: Bronchial Spasm; Female; Humans; Ketamine; Middle Aged
PubMed: 4025781
DOI: 10.1111/j.1365-2044.1985.tb10962.x -
Pediatric Pulmonology Jun 2022Lung ultrasound (LUS) has been shown to be a useful clinical tool in pediatrics, but very little is known about the LUS findings of asthma in children.
BACKGROUND
Lung ultrasound (LUS) has been shown to be a useful clinical tool in pediatrics, but very little is known about the LUS findings of asthma in children.
OBJECTIVES
The primary objective was to characterize LUS findings of pediatric patients before and after a chemically induced bronchospasm. The secondary objective was to evaluate the effect of bronchodilators on LUS findings.
METHODS
Eligible children 6-17 years old presenting for a methacholine challenge test (MCT) in a pediatric respiratory clinic were recruited. Patients with viral symptoms were excluded. A six-zone LUS protocol was performed before and after the MCT, and after bronchodilator administration; video recordings were analysed by an expert blinded to the patient characteristics and MCT results.
RESULTS
Forty-four patients were included in the study. Five patients had positive LUS findings at baseline. Nine patients out of 29 (31%) had new-onset positive LUS following a reactive MCT. There was a significant association between having a chemically induced bronchospasm and a positive LUS post-MCT (odds ratio [95% confidence interval]: 5.3 [1.0-27.7]; p = 0.05). Among patients who developed positive LUS findings post-MCT, four out of nine returned to having a negative LUS postbronchodilator administration.
CONCLUSIONS
This is the first known report of an association between LUS findings and bronchospasm in pediatric patients. It is also the first documentation of resolution of LUS findings postbronchodilator administration. Most LUS findings observed were small and limited to a few intercostal spaces. Further research is required to quantify these findings and evaluate the effect of salbutamol on LUS.
Topics: Adolescent; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Child; Humans; Lung; Methacholine Chloride; Pediatrics; Ultrasonography
PubMed: 35355448
DOI: 10.1002/ppul.25907 -
Journal of Anesthesia Feb 2015There is no strong evidence to support ventilatory management for critical limitation of expiratory flow, such as bronchospasm during anesthesia or an acute exacerbation...
There is no strong evidence to support ventilatory management for critical limitation of expiratory flow, such as bronchospasm during anesthesia or an acute exacerbation of severe asthma and chronic obstructive pulmonary disease (COPD). Animal models cannot be used to develop reproducible experimental models for conducting mechanical ventilation strategy research relating to these etiologies due to the resulting respiratory and hemodynamic instabilities. Therefore, we developed a device model by modifying a positive end-expiratory pressure (PEEP) valve that can simulate the characteristics of airway bronchoconstriction (i.e., limited peak expiratory flow and a prolonged expiratory phase). These characteristics were found to improve upon narrowing the expiratory port. We believe that this device model will facilitate future mechanical ventilation experiments.
Topics: Asthma; Bronchial Spasm; Bronchoconstriction; Computer Simulation; Equipment Design; Humans; Models, Anatomic; Positive-Pressure Respiration; Pulmonary Disease, Chronic Obstructive; Respiration, Artificial
PubMed: 24993492
DOI: 10.1007/s00540-014-1872-0 -
The Medical Journal of Australia Feb 1995
Topics: Adolescent; Adult; Bronchial Spasm; Diving; Female; Humans; Male; Middle Aged; Respiratory Function Tests; Spirometry
PubMed: 7877554
DOI: 10.5694/j.1326-5377.1995.tb126039.x