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The Journal of Urology Mar 1961
Topics: Chlortetracycline; Demeclocycline; Urinary Tract Infections; Urogenital System
PubMed: 13742176
DOI: 10.1016/S0022-5347(17)65343-6 -
Endodontics & Dental Traumatology Apr 1989Crowns from freshly extracted human third molar teeth were used to quantify the release and diffusion of corticosteroid and antibiotic tracer molecules from Ledermix...
Crowns from freshly extracted human third molar teeth were used to quantify the release and diffusion of corticosteroid and antibiotic tracer molecules from Ledermix paste used as an indirect pulp-capping agent. These molecules readily diffused through dentine and reached a peak rate of diffusion at 2 h. The rate then decreased exponentially with time. The concentrations of the drugs in the dentine were calculated; this showed that a gradient existed from the cavity floor to the pulp space. The data obtained appeared to have clinical relevance and helped explain the therapeutic benefits of this medicament when used as an indirect pulp-capping agent.
Topics: Adolescent; Adult; Demeclocycline; Dentin; Drug Combinations; Female; Humans; Male; Spectrophotometry; Triamcinolone; Triamcinolone Acetonide
PubMed: 2513180
DOI: 10.1111/j.1600-9657.1989.tb00344.x -
The American Journal of Psychiatry Jun 1983
Topics: Compulsive Behavior; Demeclocycline; Humans; Inappropriate ADH Syndrome; Water Intoxication
PubMed: 6405639
DOI: 10.1176/ajp.140.6.aj1406815 -
Archives of Dermatology Oct 1974
Topics: Adult; Demeclocycline; Humans; Libido; Male
PubMed: 4213215
DOI: No ID Found -
Clinical Medicine (London, England) Aug 2010
Topics: Antidepressive Agents; Demeclocycline; Diuretics; Drinking Behavior; Humans; Hypernatremia; Hyponatremia; Practice Guidelines as Topic; Water Intoxication
PubMed: 20853539
DOI: 10.7861/clinmedicine.10-4-418a -
Antimalarial activity of demeclocycline against Plasmodium cynomolgi bastianellii in rhesus monkeys.Annals of Tropical Medicine and... Jun 1989Demeclocycline was tested for causal prophylactic (at 25, 50 and 100 mg kg-1 dose levels), radical curative (at 25, 50, 100 and 200 mg kg-1 dose levels) and blood...
Demeclocycline was tested for causal prophylactic (at 25, 50 and 100 mg kg-1 dose levels), radical curative (at 25, 50, 100 and 200 mg kg-1 dose levels) and blood schizontocidal (at 25, 50 and 100 mg-1 dose levels) activities against Plasmodium cynomolgi B in rhesus monkeys. For causal prophylactic activity, demeclocycline extended the prepatent period at all dose levels. The maximum delay in patency was observed at 100 mg kg-1 (prepatent period = 40.66 +/- 14.57 days). For radical curative activity, relapse was also delayed at all dose levels tested, and the relapse interval was found to be 47.0 +/- 18.24 days at 200 mg kg-1. For blood schizontocidal activity, parasitaemia was initially cleared at all dose levels, followed by recrudescence in all monkeys. The recrudescence interval was found to be 17.0 +/- 5.2 days at 25 mg kg-1 and 31.0 +/- 2.7 days at 50 mg kg-1. However, three monkeys treated with 100 mg kg-1 did not show parasites in thin blood smears during the observation period, but parasites were present in thick blood smears of all the monkeys after the end of the observation period. On the other hand, all monkeys treated with 1 mg kg-1 of primaquine for causal prophylactic and radical curative activities and with 5 mg kg-1 chloroquine for blood schizontocidal activity were cured.
Topics: Animals; Demeclocycline; Female; Macaca mulatta; Malaria; Male; Plasmodium
PubMed: 2513785
DOI: 10.1080/00034983.1989.11812333 -
Canadian Medical Association Journal Nov 1980
Topics: Demeclocycline; Female; Humans; Hyponatremia; Hypothyroidism; Inappropriate ADH Syndrome; Middle Aged; Vasopressins; Water-Electrolyte Imbalance
PubMed: 6778601
DOI: No ID Found -
La Nouvelle Presse Medicale Sep 1976
Topics: Ascites; Demeclocycline; Humans; Hyponatremia; Liver Cirrhosis; Natriuresis; Water-Electrolyte Imbalance
PubMed: 824615
DOI: No ID Found -
The Journal of Investigative Dermatology Oct 1965
Topics: Blood Chemical Analysis; Darier Disease; Demeclocycline; Dermatitis; Humans; Mycosis Fungoides; Pityriasis; Psoriasis; Skin; Skin Diseases; Sunburn; Tetracycline
PubMed: 4953785
DOI: 10.1038/jid.1965.127 -
Archives of Dermatology Jul 1972
Topics: Acne Vulgaris; Adolescent; Adult; Demeclocycline; Dermatitis; Drug Hypersensitivity; Female; Humans; Male; Photosensitivity Disorders; Skin; Sunburn; Time Factors
PubMed: 4261050
DOI: No ID Found