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World Journal For Pediatric &... Jan 2023We investigated the prevalence of isolated vascular rings in the general population of Southern Nevada.
OBJECTIVE
We investigated the prevalence of isolated vascular rings in the general population of Southern Nevada.
METHODS
We identified those prenatally and postnatally diagnosed with an isolated vascular ring between January 2014 and December 2021. We included only those with vascular or ligamentous structures completely encircling the trachea and esophagus. To investigate the prevalence of isolated vascular rings, we included only those with situs solitus, levocardia, and no significant intracardiac malformations.
RESULTS
We identified 112 patients. Of the 112, 66 (59%) were female. There were approximately 211,000 total live births in Southern Nevada for the study period, for an overall prevalence of 5.3 isolated vascular rings per 10 000 live births. However, for the years 2014 to 2017, the average prevalence figure was 3.5 per 10 000 live births, and for the years 2018 to 2021, the average prevalence figure was 7.1 (range 6.5-8.0) per 10 000 live births. Simultaneously, the prenatal detection rate rose from 66% to 86%.
CONCLUSIONS
Isolated vascular rings are common cardiovascular malformations. As prenatal detection rates in the Southern Nevada general population approach 90%, the prevalence figures for isolated vascular rings appear to asymptote at about 7 per 10 000 live births.
Topics: Pregnancy; Humans; Female; Male; Vascular Ring; Cardiovascular Abnormalities; Heart; Trachea; Nevada
PubMed: 36847763
DOI: 10.1177/21501351221122972 -
Circulation Jul 1962
Topics: Heart Defects, Congenital; Humans; Levocardia; Medical Records; Situs Inversus
PubMed: 14483095
DOI: 10.1161/01.cir.26.1.108 -
American Heart Journal Jul 1983
Topics: Abdomen; Child; Child, Preschool; Female; Heart Defects, Congenital; Humans; Levocardia; Male; Radiography, Abdominal; Radiography, Thoracic; Situs Inversus; Thorax
PubMed: 6869182
DOI: 10.1016/0002-8703(83)90456-8 -
RoFo : Fortschritte Auf Dem Gebiete Der... Sep 1982Isolated levocardia combined with corrected transposition of the great arteries and complete situs inversus is rare. Due to discordant interrelationships between atria...
Isolated levocardia combined with corrected transposition of the great arteries and complete situs inversus is rare. Due to discordant interrelationships between atria and ventricles and between ventricles and great arteries, both anomalies result in a normal circulation. In the presented case no associated cardiac malformations were present and the 55-year-old woman remained symptom-free for a long time until she developed an acquired valve disease. A systematic approach to chamber localisation in complex morphologic lesions of the heart is reviewed, and the value of CT, which can be applied successfully in older children and adults is demonstrated.
Topics: Cardiac Catheterization; Female; Heart Defects, Congenital; Hemodynamics; Humans; Levocardia; Middle Aged; Mitral Valve Insufficiency; Situs Inversus; Tomography, X-Ray Computed; Transposition of Great Vessels
PubMed: 6216152
DOI: 10.1055/s-2008-1056202 -
Congenital Anomalies Dec 2011Isolated levocardia (IL) is a rare type of situs inversus in which the heart is in the normal left-side position, but the abdominal viscera are in the dextroposition....
Isolated levocardia (IL) is a rare type of situs inversus in which the heart is in the normal left-side position, but the abdominal viscera are in the dextroposition. Polysplenia is a congenital disorder affecting the asymmetric organs, including the heart, lungs, bronchi, liver, stomach, intestines, and spleen. In this report, we present a rare type satisfying the characteristics of both IL and polysplenia, confirmed by several imaging investigations, which revealed normally structured lungs and heart and the existence of the inferior vena cava (IVC), which runs on the left side, returns to the anterior-right side at the liver, and returns to the right atrium directly. Anatomical investigation and careful observation will make it possible to improve the prognosis of IL.
Topics: Abdomen; Adult; Female; Heart Defects, Congenital; Heterotaxy Syndrome; Humans; Levocardia; Lung; Tomography, X-Ray Computed; Vena Cava, Inferior; Viscera
PubMed: 22103459
DOI: 10.1111/j.1741-4520.2011.00321.x -
Surgical and Radiologic Anatomy : SRA Apr 2016Situs inversus incompletus is a rare congenital condition in which the major abdominal organs are reversed or mirrored from their normal positions. It is often...
Situs inversus incompletus is a rare congenital condition in which the major abdominal organs are reversed or mirrored from their normal positions. It is often associated with multiple congenital anomalies. We present the case of a 38-year-old woman with dyspnea and a clinical history of chronic kidney disease and kidney transplantation. Echocardiography showed a right atrial mass, and analysis of multidetector computed tomography angiography revealed the interruption of the inferior vena cava with an increase of the azygos vein and azygos continuation. These congenital malformations are often associated with deep vein thrombosis and/or pulmonary thromboembolism and explained the occurrence of dyspnea. Cardiac magnetic resonance with contrast medium confirmed the presence of the right atrial mass, the characteristics of which were attributed to interatrial thrombus, which was further confirmed by the success of thrombolytic therapy and the remission of symptoms. In conclusion, we described a case of situs inversus with levocardia in association with infrahepatic interruption of the inferior vena cava, and azygos continuation with cardiac thrombus and chronic renal failure.
Topics: Adult; Azygos Vein; Female; Humans; Levocardia; Thrombosis; Vena Cava, Inferior
PubMed: 25737490
DOI: 10.1007/s00276-015-1454-3 -
Pediatric Cardiology Apr 2010The heart develops from a simple left-right (L-R) symmetrical tube. Through a complex process of looping and remodelling, it becomes a highly L-R asymmetrical organ with... (Review)
Review
The heart develops from a simple left-right (L-R) symmetrical tube. Through a complex process of looping and remodelling, it becomes a highly L-R asymmetrical organ with distinct asymmetries in both morphology and function. Abnormal cardiac L-R patterning can result in a spectrum of defects that include, dextrocardia (a malposition of the heart to the right), isomerism of the atria (both atria being morphologically right-sided or left-sided), abnormal ventricular topology (e.g. the morphological left ventricle being dextral to the morphological right ventricle) or mirror-image topology (associated with situs inversus). Intermediate forms include abnormalities such as situs ambiguus and heterotaxia. L-R patterning abnormalities are typically associated with cardiac malformations, and it has become clear that an isolated septal, outflow tract and aortic arch malformation may be the only presenting manifestation of an L-R patterning defect. In the last two decades, there have been seminal advances in our understanding of the mechanisms controlling L-R patterning, and how mutations in L-R patterning genes result in human cardiac malformation. In this review, we provide an overview of the transcriptional mechanisms that result in asymmetric gene activation in mammals, how they receive information from signalling pathways, and how this translates to abnormal cardiac development.
Topics: Cardiovascular System; Gene Expression Regulation, Developmental; Heart; Heart Defects, Congenital; Humans; Levocardia; Signal Transduction
PubMed: 20054532
DOI: 10.1007/s00246-009-9610-3 -
Nihon Rinsho. Japanese Journal of... Oct 1974
Topics: Heart Defects, Congenital; Heart Septal Defects, Ventricular; Humans; Myocardium; Pulmonary Valve Stenosis; Situs Inversus; Transposition of Great Vessels; Tricuspid Valve Insufficiency
PubMed: 4475175
DOI: No ID Found -
Indian Journal of Gastroenterology :... Apr 1996We report a patient with isolated levocardia without cardiac or splenic defects associated with duodenal membrane.
We report a patient with isolated levocardia without cardiac or splenic defects associated with duodenal membrane.
Topics: Duodenal Diseases; Humans; Infant, Newborn; Intestinal Obstruction; Levocardia
PubMed: 8935941
DOI: No ID Found -
Electronic Physician Jan 2017Situs inversus with levocardia and congenitally corrected transposition of the great arteries represents a relatively very rare congenital condition and most patients...
Situs inversus with levocardia and congenitally corrected transposition of the great arteries represents a relatively very rare congenital condition and most patients are diagnosed in infancy or early age. This case report describes a 35-year old man with congenitally corrected transposition of the great arteries which presented with a five month history of exertional dyspnea. A diagnosis was confirmed by transesophageal echocardiogram, showing situs inversus, levocardia, atrioventricular and ventriculoarterial discordance. He underwent physiologic repair, and was discharged thirty five days after the operation, in a good general condition. Although management of the corrected transposition of the great arteries patients remains controversial, the recommendation is that physiologic repair may be the procedure of choice for some patients, particularly complicated cases.
PubMed: 28243408
DOI: 10.19082/3570