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Journal of Pediatric Surgery Jun 1966
Topics: Anti-Bacterial Agents; Colitis; Enema; Female; Hernia, Umbilical; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction; Intestinal Perforation; Male; Meconium; Peritonitis; Pneumoperitoneum
PubMed: 5911925
DOI: 10.1016/s0022-3468(66)80003-9 -
Indian Journal of Pediatrics 1996Meconium peritonitis is a chemical reaction of peritonium to meconium which occurs due to leakage of meconium into peritoneal cavity as a result of perforation of...
Meconium peritonitis is a chemical reaction of peritonium to meconium which occurs due to leakage of meconium into peritoneal cavity as a result of perforation of intestines antinatally which gets subsequently sealed. In the present retrospective study, 39 cases of neonatal peritonitis were studied. Meconium peritonitis was diagnosed if a) abdominal X-ray showed diffuse calcifications (b) abdominal paracentesis showed meconium aspirate and c) leprotomy examination. Twenty (51.3%) out of 39 cases of neonatal peritonitis were found to have meconium peritonitis. These included 14 boys and 6 girls, birth weight ranged from 1500 gms to 3200 gms and mean age of presentation included abdominal distension in 100% cases, H/O not passing meconium in 50% cases, Ascites in 45% cases and vomiting in 40% cases, 30% presented with abdominal mass. Pseudocyst formation on X-ray was seen in 23% cases which was much higher than reported in world literature. Overall mortality in meconium peritonitis was 80%. The incidence of meconium peritonitis in this part of country in much higher than reported in Western and Indian literature. The high incidence may be due to underlying cystic fibrosis because Kashmir has a more homogenous population and consanguinity is very common. A prospective study including sweat chloride testing needs to be undertaken to look into the cause for proportionately higher occurrence of meconium peritonitis in Kashmir with particular reference to cystic fibrosis.
Topics: Female; Humans; Incidence; India; Infant, Newborn; Male; Meconium; Peritonitis; Prognosis; Retrospective Studies; Risk Factors; Survival Rate
PubMed: 10829994
DOI: 10.1007/BF02845249 -
Pediatric Surgery International Mar 2024To evaluate whether infants with prenatal diagnosis of meconium peritonitis (MP) have a poorer prognosis.
OBJECTIVE
To evaluate whether infants with prenatal diagnosis of meconium peritonitis (MP) have a poorer prognosis.
METHODS
A retrospective analysis of data from infants treated with surgery from January 2008 to December 2020 was conducted. The patients were divided into prenatal diagnosis group and postnatal diagnosis group based on the timing of diagnosis. The intraoperative and postoperative parameters of the two groups of patients were compared.
RESULTS
A total of 71 cases of MP were included in the study, with 48 cases in the prenatal diagnosis group and 23 cases in the postnatal diagnosis group. The comparison of preoperative indicators between the two groups of patients showed no statistically significant differences in baseline (p > 0.05). Intraoperative indicators, including blood loss, anastomosis, retained intestinal tube length and excised intestinal tube length, showed no statistically significant differences between the two groups (p > 0.05). However, the postnatal diagnosis group had a significantly shorter operation time than the prenatal diagnosis group (p < 0.05). Postoperative indicators, including fasting time, albumin usage, complications, and abandonment or mortality rates, show no difference (p > 0.05). Nevertheless, the postnatal diagnosis group exhibited significantly shorter hospital stay and time to first bowel movement compared to the prenatal diagnosis group (p < 0.05).
CONCLUSION
Prenatal diagnosis of meconium peritonitis is associated with increased surgical complexity, prolonged hospital stay, and delayed recovery of intestinal function. However, there is no evidence of higher mortality or more complications compared to infants diagnosed postnatally, and there is no significant difference in long-term prognosis.
Topics: Infant; Pregnancy; Female; Infant, Newborn; Humans; Meconium; Retrospective Studies; Ultrasonography, Prenatal; Gestational Age; Prenatal Diagnosis; Peritonitis; Infant, Newborn, Diseases
PubMed: 38551785
DOI: 10.1007/s00383-024-05682-4 -
Fetal magnetic resonance imaging contributes to the diagnosis and treatment of meconium peritonitis.BMC Medical Imaging May 2020Meconium peritonitis (MP) is a rare fetal disease that needs to be urgently identified for surgical intervention. We report a series of 35 patients diagnosed prenatally...
BACKGROUND
Meconium peritonitis (MP) is a rare fetal disease that needs to be urgently identified for surgical intervention. We report a series of 35 patients diagnosed prenatally with MP by magnetic resonance imaging (MRI), illustrate the imaging findings and investigate the predictive value of these findings for postpartum management.
METHOD
A consecutive cohort of patients diagnosed with MP who were born at our institution from 2013 to 2018 was enrolled retrospectively. The prenatal ultrasound and MRI findings were analyzed. Fisher's exact probability test was used to evaluate the predictive value of MRI for surgical intervention between the operative group and the nonoperative group.
RESULTS
Ascites (30/35) and distended bowel loops (27/35) were two of the most common prenatal MP-related findings on fetal MRI. Of the 35 infants, 26 received surgical intervention. All fetuses with MRI scans showing bowel dilatation (14/26, p = 0.048) and micro-colorectum (13/26, p = 0.013) required surgery. There were no significant differences in the number of fetuses with meconium pseudocysts and peritoneal calcifications between the two groups.
CONCLUSION
Fetuses with bowel dilatation and micro-colorectum on MRI may need postpartum surgical intervention. Infants with only a small amount of ascites and slight bowel distention were likely to receive conservative treatment.
Topics: Adult; Cohort Studies; Female; Fetal Diseases; Gestational Age; Humans; Infant, Newborn; Magnetic Resonance Imaging; Maternal Age; Meconium; Peritonitis; Predictive Value of Tests; Pregnancy; Prenatal Diagnosis; Retrospective Studies; Ultrasonography, Prenatal; Young Adult
PubMed: 32448115
DOI: 10.1186/s12880-020-00453-8 -
Polski Przeglad Chirurgiczny Aug 1978
Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Perforation; Meconium; Peritonitis
PubMed: 714823
DOI: No ID Found -
Nederlands Tijdschrift Voor Geneeskunde Jul 1980
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Meconium; Peritonitis; Radiography
PubMed: 7402389
DOI: No ID Found -
American Journal of Clinical Pathology Aug 1982The diagnosis of meconium peritonitis has received little attention in the pathology literature. Morphologic features of meconium peritonitis can be confusing to the...
The diagnosis of meconium peritonitis has received little attention in the pathology literature. Morphologic features of meconium peritonitis can be confusing to the pathologist unfamiliar with this specific entity, especially in case of extraperitoneal lesions presenting clinically as tumor nodules in the tunica vaginalis. Unfamiliarity with this entity can lead to unnecessary removal of the testis. This paper describes four cases of meconium peritonitis and reviews the literature on the pathology, evolution and diagnostic features of the disease, with emphasis on the healed stage, presenting as a tumor mass in the inguinal canal or tunica vaginalis.
Topics: Calcinosis; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Infant, Newborn; Male; Meconium; Peritonitis; Testicular Neoplasms
PubMed: 7102819
DOI: 10.1093/ajcp/78.2.208 -
Zeitschrift Fur Kinderchirurgie : Organ... Feb 1984Meconium peritonitis being a rare anomaly, it is difficult to find the factors that determine the prognosis. In spite of the high mortality, this aspect has hardly ever...
Meconium peritonitis being a rare anomaly, it is difficult to find the factors that determine the prognosis. In spite of the high mortality, this aspect has hardly ever been studied. A retrospective study of 69 patients from the Netherlands over a 15 year period, revealed that a patient with pneumoperitoneum and a generalized type of meconium peritonitis has a relatively favourable prognosis. Despite a more optimistic outlook expressed in recent publications, an overview of the world literature involving 1084 patients shows that the mortality for this disease has not dropped in the past 15 years and still amounts to 55%.
Topics: Female; Fetal Diseases; Humans; Infant, Newborn; Intestinal Perforation; Male; Meconium; Peritonitis; Postoperative Complications; Pregnancy; Prognosis; Retrospective Studies
PubMed: 6539544
DOI: 10.1055/s-2008-1044164 -
Annals of Tropical Paediatrics 2011Intra-abdominal calcification is uncommon in newborns and has several causes of which meconium peritonitis is the most frequent. Three neonates with intra-abdominal...
Intra-abdominal calcification is uncommon in newborns and has several causes of which meconium peritonitis is the most frequent. Three neonates with intra-abdominal calcification as a complication of meconium peritonitis are presented. The types of meconium peritonitis were cystic, meconium pseudocyst and meconium ascites. Two required surgical intervention. Meconium peritonitis should be considered in newborns with intra-abdominal calcification.
Topics: Adult; Calcinosis; Female; Humans; Infant, Newborn; Male; Meconium; Peritonitis; Radiography, Abdominal; Ultrasonography
PubMed: 21575323
DOI: 10.1179/1465328111Y.0000000001 -
Medicine Sep 2019Advancements in diagnostic modalities have improved the diagnosis of meconium peritonitis (MP) both in utero and ex utero. This study aimed to determine the efficacy of... (Comparative Study)
Comparative Study Observational Study
Advancements in diagnostic modalities have improved the diagnosis of meconium peritonitis (MP) both in utero and ex utero. This study aimed to determine the efficacy of prompt prenatal and postnatal diagnoses of MP on the postnatal outcomes of these patients.We conducted a retrospective chart review of neonates with MP admitted to the Mackay Memorial Hospital Systems from 2005 to 2016. The prenatal diagnoses, postnatal presentations, surgical indications, operative methods, types of MP, operative findings, associated anomalies, morbidities, patient outcomes, and survival rates were analyzed. Morbidities included postoperative adhesion ileus, bacteremia, and short bowel syndrome. We also performed subgroup analyses of the morbidity and survival rates of prenatally versus postnatally diagnosed patients, as well as inborn versus outborn neonates.Thirty-seven neonates with MP were enrolled. Of this number, 24 (64.9%) were diagnosed prenatally. Twenty-two (59.5%) were born preterm. The most common prenatal sonographic findings included fetal ascites followed by dilated bowel loops. Abdominal distention was the most frequent postnatal symptom. Thirty-four (91.9%) neonates underwent surgery, whereas 3 were managed conservatively. Volvulus of the gastrointestinal tract was the most frequent anatomic anomaly. The total morbidity and survival rates were 37.8% and 91.9%, respectively. The morbidity and survival rates did not differ significantly between prenatally and postnatally diagnosed patients (37.5% vs 33.3%, P = 1.00; 91.7% vs 92.3%, P = 1.00, respectively). Inborn and outborn patients did not differ in terms of morbidity and survival rates (27.3% vs 53.3%, P = .17; 100% vs 80.0%, P = .06, respectively).Although not statistically significant, inborn MP neonates had higher survival rates when compared with outborn MP neonates. Prompt postnatal management at tertiary centers seemed crucial.
Topics: Ascites; Dilatation, Pathologic; Early Diagnosis; Female; Humans; Infant, Newborn; Intestinal Volvulus; Intestines; Meconium; Patient Outcome Assessment; Peritonitis; Pregnancy; Retrospective Studies; Survival Rate; Time-to-Treatment; Ultrasonography, Prenatal
PubMed: 31574807
DOI: 10.1097/MD.0000000000017079