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Bulletin Et Memoires de La Societe Des... 1967
Topics: Humans; Infant, Newborn; Meconium; Peritonitis
PubMed: 5595273
DOI: No ID Found -
Der Chirurg; Zeitschrift Fur Alle... Jan 1959
Topics: Child; Humans; Infant; Infant, Newborn, Diseases; Meconium; Osteosclerosis; Peritonitis
PubMed: 13629751
DOI: No ID Found -
Casopis Lekaru Ceskych Dec 1955
Topics: Child; Humans; Infant; Meconium; Peritonitis
PubMed: 13284769
DOI: No ID Found -
Igaku Kenkyu. Acta Medica May 1974
Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Meconium; Peritonitis
PubMed: 4476163
DOI: No ID Found -
Acta Chirurgica Belgica Nov 1962
Topics: Fetal Diseases; Humans; Infant, Newborn, Diseases; Meconium; Peritonitis
PubMed: 13987689
DOI: No ID Found -
Belgisch Tijdschrift Voor Geneeskunde Nov 1955
Topics: Child; Fetal Diseases; Humans; Infant; Infant, Newborn, Diseases; Meconium; Peritonitis
PubMed: 13283957
DOI: No ID Found -
American Journal of Perinatology Nov 2009Generalized arterial calcification of infancy (GACI) is a rare genetic disorder consisting of diffuse arterial calcification and intimal proliferation. The disease... (Review)
Review
Generalized arterial calcification of infancy (GACI) is a rare genetic disorder consisting of diffuse arterial calcification and intimal proliferation. The disease typically results in progressive arterial stenosis and frequently leads to death from myocardial ischemia by 6 months of life. Affected infants are usually diagnosed before birth or in the neonatal period with symptoms of congestive heart failure. Therapy with bisphosphonate has been used to treat the condition, but with inconsistent results. The disease is associated with mutations in ENPP1 in the majority of the cases. Here we report a unique case of GACI associated with in utero meconium peritonitis and without coding region mutations of the ENPP1 gene. GACI should be considered in the differential diagnosis in infants presenting with arterial calcifications and congenital anomalies of the gastrointestinal tract.
Topics: Abnormalities, Multiple; Adult; Aortic Diseases; Calcinosis; Clubfoot; Female; Humans; Infant, Newborn; Male; Meconium; Peritonitis; Phosphoric Diester Hydrolases; Pyrophosphatases; Scoliosis; Ultrasonography, Prenatal
PubMed: 19452427
DOI: 10.1055/s-0029-1223282 -
Prenatal Diagnosis Aug 1992By chance, we had the opportunity to make serial sonographic observations of the extrusion of meconium in a case of meconium peritonitis. Inflammation leads to exudative...
By chance, we had the opportunity to make serial sonographic observations of the extrusion of meconium in a case of meconium peritonitis. Inflammation leads to exudative processes and production of fluid (ascites) in the fetal abdomen. Sonography at that stage of the disease may lead to a misdiagnosis such as 'fetal ascites' or 'non-immune hydrops'. After bowel perforation and extrusion of meconium, the latter appears as a solitary mass inside fetal ascites or as disseminated echogenic masses distributed subdiaphragmatically or perihepatically. Within a couple of days, in most cases the echogenicity of the masses increases. Calcifications lead to distinct shadowing. These calcifications are often the only visible signs of a previous meconium peritonitis. Serial sonograms are essential for the management of pregnancies with meconium peritonitis. If the amount of fetal ascites does not increase and no signs of cardiovascular stagnation appear, no invasive intrauterine diagnostic and therapeutic steps are required. In none out of the nine cases was a cause found.
Topics: Adult; Ascites; Female; Fetal Diseases; Humans; Hydrothorax; Meconium; Peritonitis; Pregnancy; Pregnancy Outcome; Ultrasonography, Prenatal
PubMed: 1438058
DOI: 10.1002/pd.1970120802 -
Clinical Radiology Feb 2018To use prenatal magnetic resonance imaging (MRI) to define features of meconium peritonitis (MP) and analyse the relationship between prenatal MRI findings and postnatal...
AIM
To use prenatal magnetic resonance imaging (MRI) to define features of meconium peritonitis (MP) and analyse the relationship between prenatal MRI findings and postnatal outcomes.
MATERIALS AND METHODS
Eight cases were enrolled who had been diagnosed with MP through prenatal MRI; the diagnoses were confirmed at surgery and pathology or follow-up. MP was diagnosed by the findings of meconium ascites, meconium pseudocyst, or dilated bowel loops. Prenatal follow-up after diagnosis by MRI was performed by ultrasound.
RESULTS
Prenatal MRI findings included massive meconium ascites (five out of eight cases), a small meconium pseudocyst (one out of eight), a large meconium pseudocyst along with a dilated bowel loop (one out of eight), a dilated bowel loop alone (one out of eight), and micro-colorectum (six out of eight). Six fetuses showed abdominal distension, bilious vomiting, and no normal meconium at birth; they underwent exploratory laparotomies and subsequently, survived and prospered. Only one fetus (with a small meconium pseudocyst) received conservative treatment. There was one mortality, and the cause of death was full-bowel necrosis.
CONCLUSION
Prenatal MRI may be helpful for diagnosing MP, in cases where the specific MRI findings are persistent meconium ascites, a dilated bowel loop, micro-colorectum, and meconium pseudocyst. In particular, a micro-colorectum might indirectly reflect ileum atresia, which requires postnatal surgery.
Topics: Female; Humans; Infant, Newborn; Magnetic Resonance Imaging; Male; Meconium; Peritonitis; Pregnancy; Prenatal Diagnosis
PubMed: 28954695
DOI: 10.1016/j.crad.2017.08.006 -
Prenatal Diagnosis Nov 2003Intra-uterine bowel perforation can occur secondary to a variety of abnormalities and cause sterile peritonitis in the fetus (generalised = type I). If sealing of the...
OBJECTIVES
Intra-uterine bowel perforation can occur secondary to a variety of abnormalities and cause sterile peritonitis in the fetus (generalised = type I). If sealing of the perforation does not take place, a thick-walled pseudo-cyst can form (type II).
METHODS
Over a 12-year period, 21 616 pregnancies were screened for gastro-intestinal malformations using prenatal ultrasound. We identified 1077 cases suspicious of surgically correctable malformations. Post-natal diagnoses and outcome were worked up retrospectively.
RESULT
We found 96 fetuses with suspected gastro-intestinal malformations. Prenatal bowel perforation with meconium peritonitis was confirmed in 11 cases. In 5 of these 11, the correct diagnosis had been predicted prenatally. One child presented as a fetal and neonatal emergency (case report). Ten of the eleven infants were operated on during their first day of life. Intra-operative findings were atresia (n = 4), meconium ileus (n = 6) and no obvious cause (n = 1). Two children suffered fatal complications.
CONCLUSION
Meconium peritonitis and meconium pseudo-cysts as its special manifestation are assessable by prenatal diagnosis but present in different ways. They can present as fetal ascites or echogenic bowel and cause fetal or neonatal distress, requiring close observation and highly specialised care.
Topics: Adult; Cysts; Female; Fetal Diseases; Humans; Infant, Newborn; Intestinal Perforation; Male; Meconium; Peritonitis; Pregnancy; Pregnancy Trimester, Third; Retrospective Studies; Treatment Outcome; Ultrasonography, Prenatal
PubMed: 14634976
DOI: 10.1002/pd.720