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BJR Case Reports Dec 2018Barium enema investigation is regarded as a safe investigative procedure. Rarely, it may cause complications such as colonic perforation and barium intravasation. Barium...
Barium enema investigation is regarded as a safe investigative procedure. Rarely, it may cause complications such as colonic perforation and barium intravasation. Barium intravasation may be caused by the inadvertent introduction of the catheter into the vagina, thereby into the vaginal venous plexus. It may also occur through mechanical colonic perforation with the catheter, or via diseased bowel conditions. This may lead to complications such as liver microabscesses, massive pulmonary embolism, hypovolemic shock, disseminated intravascular coagulopathy and even sudden death. With that in mind, we would like to report an interesting case of barium intravasation into the portal venous system via the vagina venous plexus. The patient experienced abdominal discomfort with mild per vaginal bleed and went into disseminated intravascular coagulopathy. She received supportive management and she made a full recovery.
PubMed: 30931138
DOI: 10.1259/bjrcr.20180017 -
Indian Journal of Dermatology 2015This paper describes a typical case of poikiloderma vasculare atrophicans (PVA) in a 48-year-old female. Histologically, the features were suggestive of PVA with the...
This paper describes a typical case of poikiloderma vasculare atrophicans (PVA) in a 48-year-old female. Histologically, the features were suggestive of PVA with the absence of Pautrier's microabscess or atypical lymphoid cells. The biopsy specimen was positive for cluster of differentiation (CD) 8 on immunohistochemical staining. Its exact pathogenesis remains obscure, and it remains unclear whether PVA actually is mycosis fungoides (MF), a forme fruste of MF, or a distinct and benign dermatosis with CD8+ phenotype that can perhaps be labeled as PVA. However, it has a long benign clinical course without progression to tumor stage of MF in most cases, and its status within the spectrum of cutaneous T-cell lymphoma remains poorly understood. Yet it is imperative to distinguish PVA from poikilodermic MF.
PubMed: 25814753
DOI: 10.4103/0019-5154.152566 -
Seminars in Respiratory and Critical... Oct 2004There are three major vasculitis syndromes that affect the lung: Wegener's granulomatosis (WG), Churg-Strauss syndrome (CSS), and microscopic polyangiitis (MPA). The...
There are three major vasculitis syndromes that affect the lung: Wegener's granulomatosis (WG), Churg-Strauss syndrome (CSS), and microscopic polyangiitis (MPA). The pathology of pulmonary vasculitis is complicated because it requires correlation with clinical, laboratory, and radiological features; there is overlap in some histological features among the vasculitis syndromes; biopsies early in the course of disease or after therapy may show atypical or incomplete histological features; the differential diagnosis is complex and includes infection that should not be treated with corticosteriods or immunosupressive agents; and few pathologists have much experience with these cases. Major histological features of necrosis, granulomatous inflammation, and vasculitis characterize WG. The inflammatory consolidation consists of a mixture of neutrophils, lymphocytes, plasma cells, macrophages, giant cells, and eosinophils. Necrosis may take the form of neutrophil microabscesses or geographic necrosis. Granulomas may take several forms, including scattered or loose clusters of giant cells, palisading histiocytes or giant cells lining the border of geographic necrosis or microabscesses, and palisading microgranulomas. Sarcoidal granulomas are very rare. CSS may show eosinophilic pneumonia, allergic granulomas, and eosinophilic vasculitis. Asthmatic bronchitis may also be present. Biopsies from CSS patients are rare because this syndrome is usually diagnosed clinically. Microscopic polyangiitis demonstrates neutrophilic capillaritis and diffuse alveolar hemorrhage.
PubMed: 16088493
DOI: 10.1055/s-2004-836141 -
Radiographics : a Review Publication of... 2022Splenic lesions are commonly discovered incidentally at imaging, without clinical signs or symptoms that may aid in diagnosis. As such, the differential diagnosis and...
Splenic lesions are commonly discovered incidentally at imaging, without clinical signs or symptoms that may aid in diagnosis. As such, the differential diagnosis and subsequent management are based primarily on imaging characteristics. Much has been written about the myriad pathologic conditions that can occur in the spleen; however, there is little guidance on the approach to an incidental splenic mass. Applying an approach frequently used in imaging to the splenic mass-based on the number and consistency of lesions and refined by supplementary imaging features-allows formulation of a useful differential diagnosis. Solitary cystic masses include true cysts, pseudocysts, and parasitic cysts. When multiple cystic lesions are present, the differential diagnosis expands to include infectious lesions (abscess or microabscesses) and lymphangioma (a benign cystic neoplasm). Hemangioma is the most common solitary solid mass, although other vascular lesions (hamartoma, sclerosing angiomatoid nodular transformation) and nonvascular lesions (inflammatory pseudotumor, lymphoma) manifest as solitary and solid. When multiple solid masses are present, diffuse inflammatory disease (sarcoidosis), littoral cell angioma, and lymphoma should be considered. Malignancies, such as angiosarcoma or metastasis, can manifest as solitary or multiple and solid or cystic masses but are typically associated with symptoms or widespread primary malignancy. Careful assessment of the multimodality imaging characteristics of splenic lesions based on this approach aids the radiologist faced with the incidental splenic lesion. Work of the U.S. Government published under an exclusive license with the RSNA.
Topics: Abscess; Cysts; Diagnosis, Differential; Humans; Lymphoma; Multimodal Imaging; Splenic Diseases; Splenic Neoplasms
PubMed: 35302864
DOI: 10.1148/rg.210071 -
Reviews of Infectious Diseases 1990Kluyvera, a new genus in the family Enterobacteriaceae, was formerly known as enteric group 8 and as API group 1. Although Kluyvera species have been isolated from... (Review)
Review
Kluyvera, a new genus in the family Enterobacteriaceae, was formerly known as enteric group 8 and as API group 1. Although Kluyvera species have been isolated from various clinical specimens such as sputum, urine, stool, and blood, the clinical significance of these isolates has not been established. Recently, we treated a child who developed peritonitis due to Kluyvera ascorbata. The repeated isolation of the organism in pure culture from the peritoneal fluid and its isolation from postmortem subdiaphragmatic microabscesses suggest that Kluyvera can be clinically significant. Review of the literature clearly indicates that Kluyvera strains are infrequent but potentially dangerous pathogens in humans. Further experience is needed to determine the therapeutic efficacy of the various antibiotics to which these bacteria are sensitive in vitro.
Topics: Adolescent; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Peritonitis
PubMed: 2193346
DOI: 10.1093/clinids/12.3.399 -
Clinical Case Reports Mar 2017Hepatic abscess due to Brucella species is an extremely rare complication especially in acute illness. Here, we report a case of hepatic microabscesses probably caused...
Hepatic abscess due to Brucella species is an extremely rare complication especially in acute illness. Here, we report a case of hepatic microabscesses probably caused by in a 33-year-old woman with acute infection who was successfully treated with a combination of doxycycline and rifampicin for 3 months.
PubMed: 28265378
DOI: 10.1002/ccr3.810 -
Journal of the College of Physicians... Jun 2018During recent epidemic of dengue fever in Peshawar, there has been a significant increase in dengue-associated admission in hospitals. We performed a postmortem...
During recent epidemic of dengue fever in Peshawar, there has been a significant increase in dengue-associated admission in hospitals. We performed a postmortem examination of dengue-related death in our hospital. He was a young man, who was given supportive care at our tertiary care hospital, despite that he died on seventh day of admission. The autopsy findings in this case included multiple organ involvement including heart, lungs, kidneys and brain. There was histopathological finding of microabscesses in heart, lungs, brain and kidneys, which have not been reported in the literature yet. In patients with severe dengue, deaths do occur despite current supportive management. Knowing the pathological processes involved in severe disease, it can help identify early predictors of disease severity and help applying adequate clinical interventions.
Topics: Abscess; Autopsy; Brain; Humans; Kidney; Lung; Male; Myocardium; Severe Dengue; Young Adult
PubMed: 29866250
DOI: 10.29271/jcpsp.2018.06.S137 -
ACG Case Reports Journal Jul 2022Hepatic abscesses in premature infants are rare with less than 100 case reports documented in literature. We report a case of a premature infant diagnosed with hepatic...
Hepatic abscesses in premature infants are rare with less than 100 case reports documented in literature. We report a case of a premature infant diagnosed with hepatic microabscesses secondary to eosinophilic colitis. A 33 4/7-week preterm female neonate presented with bilious emesis, abdominal distention, and severe hematochezia. Eosinophilic enterocolitis was suspected. Hypoechoic regions in the anterior liver identified on computed tomography were considered liver microabscesses. This unique case exemplifies how prematurity increases the risk of mucosal damage in the presence of eosinophilic colitis causing enteric bacteria to seed into the liver through the portal vein, resulting in hepatic microabscesses.
PubMed: 35784499
DOI: 10.14309/crj.0000000000000817 -
Annals of Internal Medicine Oct 1976Four patients in whom endocarditis had been verified at autopsy had the pathogenic organism isolated from aspirates of Osler's nodes. In three cases the responsible...
Four patients in whom endocarditis had been verified at autopsy had the pathogenic organism isolated from aspirates of Osler's nodes. In three cases the responsible organism was identified in Gram stains made from aspirates. The etiologic agent was Staphylococcus aureus in three cases and Candida albicans in one case. Histologic examination of an Osler's node from one of the patients with S. aureus endocarditis showed a microabscess in the papillary dermis together with microemboli in nearby dermal arterioles. Workers previously have interpreted similar histologic findings as consistent with perivasculitis resulting from an immunologic reaction to the pathogenic organism. The present findings support Osler's original contention that the skin lesions that bear his name are "in all of probability caused by minute emboli".
Topics: Adolescent; Adult; Candida albicans; Embolism; Endocarditis, Bacterial; Female; Humans; Male; Skin; Skin Manifestations; Staphylococcus aureus
PubMed: 788582
DOI: 10.7326/0003-4819-85-4-471 -
Urology Apr 1975A case of infected hydrocele associated with epididymal microabscess in a neonate is presented. Only 1 similar case is described and that was asssociated with a ruptured...
A case of infected hydrocele associated with epididymal microabscess in a neonate is presented. Only 1 similar case is described and that was asssociated with a ruptured appendix. Attention is called to the unusual cause in this case, and emphasis is placed on the need for hospitalization and surgical exploration in cases of scrotal pathology in infants.
Topics: Abscess; Diagnostic Techniques, Surgical; Epididymis; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Testicular Hydrocele; Testis
PubMed: 1129872
DOI: 10.1016/0090-4295(75)90082-5