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Pediatrics Aug 1984
Topics: Buttocks; Child Abuse; Diagnosis, Differential; Humans; Infant; Pigmentation Disorders
PubMed: 6462843
DOI: No ID Found -
Pediatric Dermatology 2013To determine the frequency and clinical presentation of Mongolian spots (MS) and assess their evolution with age, this study was conducted in three phases. The first...
To determine the frequency and clinical presentation of Mongolian spots (MS) and assess their evolution with age, this study was conducted in three phases. The first phase examined 2,313 babies born at Jawaharlal Institute of Postgraduate Medical Education and Research between October and December 2010 for the number, size, shape, color, and distribution of MS. Babies with MS were followed up at 6 months and 1 year, in the second and third phases, respectively, to note the evolution of the patches. Of 2,313 babies, 1,524 (65.9%) had MS. The majority had a single patch (n = 790), measuring less than 5 cm (n = 932), with an irregular shape (n = 981) and a blue-green color (n = 577). The most common site was sacral (n = 1,203), and the most common extrasacral site was a lower extremity (n = 156). A single case of superimposed MS was recorded. Male sex and prematurity were significantly associated with MS (p < 0.05). At 6 months, 73 of 634 babies (11.5%) showed fading and 83 (13.1%) showed complete disappearance. At 1 year, 90 (14.2%) showed fading and 268 (42.3%) showed complete disappearance. Multiple MS (p < 0.05), extrasacral position (p < 0.05), size larger than 10 cm (p < 0.05), and dark-colored lesions (blue/blue-black) (p < 0.05) were significantly associated with persistence beyond 1 year. Seven hundred ninety babies (51.8%) had a single MS. More than 40% of MS disappeared by 1 year. Multiple patches, extrasacral position, size larger than 10 cm, and dark-colored lesions were markers of persistence beyond 1 year.
Topics: Female; Follow-Up Studies; Humans; India; Infant; Infant, Newborn; Infant, Premature; Male; Mongolian Spot; Prevalence; Prospective Studies; Remission, Spontaneous; Risk Factors; Sex Distribution; Skin; Skin Neoplasms
PubMed: 23834326
DOI: 10.1111/pde.12191 -
Forensic Science International Oct 2021Mongolian Spots (MS) are the most common birthmarks in newborn children. The condition presents as greenish-bluish to greyish macules, particularly in the lumbosacral...
Mongolian Spots (MS) are the most common birthmarks in newborn children. The condition presents as greenish-bluish to greyish macules, particularly in the lumbosacral area. The incidents of MS can vary in different ethnic groups and normally fade in early childhood. MS can be misinterpreted as hematomas because of the color and the predilection site. This paper discusses the case of a two-month old female admitted to hospital under suspicion of child abuse. The clinical forensic examination of the infant and her two older sisters found the children were in good health and did not show signs of abuse, despite the infant presenting with multiple and extensive greyish-blue macules. Thirteen months later, a welfare officer requested another forensic examination on the now 15-month-old child after noticing greyish-blue macules. Following a second examination, no evidence of abuse was found. This case illustrates the issue of MS as a differential diagnosis of hematomas.
Topics: Child Abuse; Diagnosis, Differential; Female; Hematoma; Humans; Infant; Mongolian Spot
PubMed: 34478897
DOI: 10.1016/j.forsciint.2021.110964 -
Archiv Fur Kinderheilkunde Jul 1965
Review
Topics: Black or African American; Asian People; Humans; Infant; Infant, Newborn; Pigmentation Disorders
PubMed: 5322095
DOI: No ID Found -
Neonatal Network : NN 2005Mongolian spots are the most frequently seen birthmarks in infants. They have almost universally been regarded as benign cutaneous manifestations that have no clinical... (Review)
Review
Mongolian spots are the most frequently seen birthmarks in infants. They have almost universally been regarded as benign cutaneous manifestations that have no clinical significance. Recently, however, there have been studies suggesting that Mongolian spots manifest more often in children with certain inborn errors of metabolism, including mucopolysaccharidosis and GM1 gangliosidosis.
Topics: Diagnosis, Differential; Gangliosidosis, GM1; Humans; Infant, Newborn; Mongolian Spot; Mucopolysaccharidoses; Skin Neoplasms
PubMed: 15717433
DOI: 10.1891/0730-0832.24.1.31 -
Journal of the European Academy of... Jun 2019Dermal melanocytoses (DMs) comprise a heterogeneous group of benign lesions, located on skin and mucous membranes, characterized by dendritic melanocytes in the dermis.... (Review)
Review
Dermal melanocytoses (DMs) comprise a heterogeneous group of benign lesions, located on skin and mucous membranes, characterized by dendritic melanocytes in the dermis. Although they share common histopathological features, some variants may present only as bluish or grey patches, some only as papules/nodules/plaques and others may show combination of all of these lesions. Despite the fact that blue naevus (BN) is typically characterized with papulonodular lesions, its variants may show all of the aforementioned presentations. Mongolian spot, naevus of Ota and naevus of Ito are patchy DMs distinguished by their specific localizations. Apart from these classical forms, many atypical variants without unique clinicopathological characteristics have been described in the literature making the nomenclature of DMs more complicated. However, congenital dermal melanocytosis and acquired dermal melanocytosis seem to be crucial umbrella terms that encompass all patchy DMs in atypical locations. Papules or subcutaneous nodules on patchy lesions and association of epidermal pigmentation presenting as brownish patches may be encountered as rare features of DMs. On the other hand, delayed-onset subcutaneous nodules may be typical presentations of melanoma in patchy DMs; therefore, they deserve special attention. Large plaque-type BN with subcutaneous cellular nodules is a newly described entity, harbouring clinical features of various DMs together and has a high risk of melanoma. The whole spectrum of dermal dendritic melanocytic proliferations is discussed including novelties and controversial issues.
Topics: Cell Proliferation; Humans; Melanocytes; Nevus, Blue; Skin; Skin Neoplasms
PubMed: 30767282
DOI: 10.1111/jdv.15492 -
Bulletin de La Societe Francaise de... 1960
Topics: Mongolian Spot; Pigmentation
PubMed: 13688157
DOI: No ID Found -
Pediatric Clinics of North America Aug 1991Skin disorders are commonly seen in the neonatal period. A recent survey of neonates demonstrated that almost every neonate had some skin lesion. The most common skin... (Review)
Review
Skin disorders are commonly seen in the neonatal period. A recent survey of neonates demonstrated that almost every neonate had some skin lesion. The most common skin findings are desquamation, Epstein's pearls, sebaceous hyperplasia, milia, toxic erythema, salmon patch, hypertrichosis, and Mongolian spot. In addition to these common cutaneous findings, other disorders may exist and are discussed in this article.
Topics: Fat Necrosis; HIV Infections; Humans; Infant; Infant, Newborn; Skin Diseases
PubMed: 1870904
DOI: 10.1016/s0031-3955(16)38152-4 -
South African Medical Journal =... Oct 1951
Topics: Asian People; Humans; Mongolian Spot; Pigmentation
PubMed: 14892910
DOI: No ID Found -
Histopathology Nov 2004Dermal dendritic melanocytic proliferations are a broad group of congenital and acquired melanocytic lesions characterized by the presence of dermal spindled and... (Review)
Review
Dermal dendritic melanocytic proliferations are a broad group of congenital and acquired melanocytic lesions characterized by the presence of dermal spindled and dendritic cells resembling melanocytes migrating from the neural crest to the epidermis. Historically, they were subdivided into dermal melanocytoses (naevus of Ota, Ito, Mongolian spot and related conditions), blue naevi and malignant blue naevi. The purpose of this review is to provide an update on recent developments in the field with emphasis on new entities and their differential diagnosis.
Topics: Animals; Cell Division; Horses; Humans; Melanocytes; Nevus, Blue; Skin Neoplasms
PubMed: 15500647
DOI: 10.1111/j.1365-2559.2004.01975.x