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The Pan African Medical Journal 2021Pleomorphic adenoma is a benign mixed tumor, which is composed of myoepithelial and epithelial cells. A fibrous capsule separates these cells from the surrounding...
Pleomorphic adenoma is a benign mixed tumor, which is composed of myoepithelial and epithelial cells. A fibrous capsule separates these cells from the surrounding tissues. Pleomorphic adenoma is the most common salivary gland tumour accounting for 40-70% of all major and minor salivary gland tumours. It is also the commonest minor salivary gland benign tumours accounting for 70% of all tumours. Hard palate is the commonest site followed by upper lip, buccal mucosa, tongue, floor of mouth, retromolar trigone. This case report discusses a case of pleomorphic adenoma of hard palate in an old man after complete excision of the tumour, which was confirmed by a biopsy specimen.
Topics: Adenoma, Pleomorphic; Adult; Humans; Male; Palatal Neoplasms; Palate, Hard
PubMed: 33912316
DOI: 10.11604/pamj.2021.38.146.26508 -
Journal of Medical Case Reports Jun 2017Myoepitheliomas account for less than 1% of salivary gland tumors. They mostly affect the parotid glands of adults during the third to fifth decades.
BACKGROUND
Myoepitheliomas account for less than 1% of salivary gland tumors. They mostly affect the parotid glands of adults during the third to fifth decades.
CASE PRESENTATION
A 10-year-old Indian boy reported a small swelling in the roof of his mouth of 10 days' duration. History revealed that the lesion was painless and not associated with bleeding or pus discharge. On examination, a purplish well-circumscribed growth was noted on his posterior hard palate. Magnetic resonance imaging was suggestive of a well-encapsulated hemangioma. An excisional biopsy was performed and histopathology along with immunohistochemistry analysis showed that the lesion was a spindle cell variant of benign myoepithelioma.
CONCLUSION
Palatal myoepitheliomas are rare and their occurrence in young individuals is rarer.
Topics: Biopsy; Child; Diagnosis, Differential; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Myoepithelioma; Palatal Neoplasms; Palate, Hard; Rare Diseases; Treatment Outcome
PubMed: 28577557
DOI: 10.1186/s13256-017-1321-4 -
Journal of Stomatology, Oral and... Feb 2023
Topics: Humans; Palatal Neoplasms
PubMed: 36241159
DOI: 10.1016/j.jormas.2022.10.005 -
Journal of the College of Physicians... Dec 2017
Topics: Adult; Humans; Male; Myxoma; Palatal Neoplasms; Palate
PubMed: 29185414
DOI: No ID Found -
The Journal of the Louisiana State... Feb 1991Carcinoma of the soft palate and uvula is a rare form of oropharyngeal neoplasm with incidence ranging from 5% to 12% of all oropharyngeal carcinomas. The lesions are... (Review)
Review
Carcinoma of the soft palate and uvula is a rare form of oropharyngeal neoplasm with incidence ranging from 5% to 12% of all oropharyngeal carcinomas. The lesions are more commonly found in men in the sixth and seventh decade of life. Because of the high incidence of potential velopharyngeal incompetence, surgical resections are usually reserved for the lesions confined to the uvula, where larger lesions are treated with radiation therapy.
Topics: Female; Humans; Incidence; Lymphatic Metastasis; Male; Palatal Neoplasms; Palate, Soft; Survival Rate; Uvula
PubMed: 2010666
DOI: No ID Found -
Journal of Oral and Maxillofacial... Mar 2014Although the most common neoplastic lesion of the oral cavity is squamous cell carcinoma (SCC), primary neoplastic lesions of the hard palate have not been...
PURPOSE
Although the most common neoplastic lesion of the oral cavity is squamous cell carcinoma (SCC), primary neoplastic lesions of the hard palate have not been systematically reviewed to date. The aim of this study was to determine the histopathologic composition and characteristics of neoplasms of the hard palate.
MATERIALS AND METHODS
A retrospective analysis of 66 patients with a primary neoplasm of the hard palate managed at the authors' institution from 1985 through 2012 was performed. Demographic features, malignancy rate, histopathologic characteristics and distribution, TNM staging results, metastasis patterns, and management strategies were investigated.
RESULTS
The sample was composed of 66 patients (mean age, 45.0 yr; 57.6% men). Neoplasms were benign in 57.6% of cases and malignant in 42.4%. Epithelial neoplasms and mesenchymal neoplasms were encountered in 52 patients (78.8%) and 14 patients (21.2%), respectively. Minor salivary gland tumors (MSGTs) were the most common histopathologic group (60.6%), followed by benign mesenchymal tumors (15.2%), SCCs (12.1%), malignant melanomas (6.1%), lymphomas (3.0%), and sarcomas (3.0%). Although 75.0% of malignant epithelial neoplasms were at an advanced stage, there were no pN+ SCC or malignant MSGT cases at presentation.
CONCLUSION
The most common neoplasms of the hard palate were MSGTs. SCCs were relatively rare in this series. Although three-fourths of neoplasms were at an advanced stage, neck metastasis was not a characteristic of malignant epithelial neoplasms located in the hard palate.
Topics: Carcinoma, Squamous Cell; Female; Humans; Lymphoma; Male; Melanoma; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Palatal Neoplasms; Palate, Hard; Radiotherapy, Adjuvant; Retrospective Studies; Salivary Gland Neoplasms; Sarcoma
PubMed: 24139293
DOI: 10.1016/j.joms.2013.08.019 -
The Journal of Craniofacial Surgery May 2011Pleomorphic adenoma is the most common mixed benign tumor of major salivary glands. Approximately 80% of these tumors arise in the parotid gland, whereas 7% arise in the... (Review)
Review
Pleomorphic adenoma is the most common mixed benign tumor of major salivary glands. Approximately 80% of these tumors arise in the parotid gland, whereas 7% arise in the minor salivary glands. The most common sites for minor salivary gland where pleomorphic adenoma arises are the palates followed by lips and cheek. We report a palate mass in a 46-year-old male patient. The initial cytologic diagnosis by fine-needle aspiration biopsy was pleomorphic adenoma. This report describes a case of pleomorphic adenoma regarding all distinctive diagnoses with the review of the literature.
Topics: Adenoma, Pleomorphic; Adult; Biopsy, Fine-Needle; Diagnosis, Differential; Humans; Male; Palatal Neoplasms; Palate, Hard; Radiography, Panoramic
PubMed: 21586967
DOI: 10.1097/SCS.0b013e3182108f8b -
The Journal of Laryngology and Otology Oct 1971
Topics: Adenoma; Child; Female; Humans; Palatal Neoplasms; Staining and Labeling
PubMed: 4106429
DOI: 10.1017/s0022215100074491 -
European Annals of Otorhinolaryngology,... Dec 2021
Topics: Humans; Palatal Neoplasms; Palate
PubMed: 33933402
DOI: 10.1016/j.anorl.2021.04.002 -
Medicina Oral, Patologia Oral Y Cirugia... Dec 2007Myoepithelioma is a benign neoplasm of salivary glands, represents 1.5 % of all salivary glands neoplasm. The plasmacytoid myoepithelioma from palate salivary glands is... (Review)
Review
INTRODUCTION
Myoepithelioma is a benign neoplasm of salivary glands, represents 1.5 % of all salivary glands neoplasm. The plasmacytoid myoepithelioma from palate salivary glands is considered as a rare entity, at date it has been reported 14 cases. It is present one case of plasmacytoid myoepithelioma of palate.
CASE REPORT
A Hispanic female of 28 years old presented a not-ulcerate, painless ovoid swelling at left side of hard palate with a one year and a half of evolution. An excisional biopsy was done. The sample was fixed at 10% buffer formalin, embedded in paraffin, cuts at 5 micron and stained with H-E. Microscopically, the lesion was composed by myoepithelial neoplastic cells characterized by a round ovoid silhouette, an eccentric nuclei of dense chromatin and eosinophilic cytoplasm. In some myoepithelial neoplastic cells were identifies intranuclear cytoplasmatic inclusions. The lesion was analysed with immunohistochemical technique using the follow antibodies: vimentin, citokeratin AE1/AE3, S100 protein and actin muscle specific. We observe positive immunoreactivity against vimentin, citokeratin, S100 protein and actin muscle specific. A diagnosis of plasmacytoid myoephitelioma of palate salivary glands was done. Our findings supports the suggestion about plasmacytoid myoepithelioma is an independent entity. The histological diagnostic parameters of plasmacytoid myoepithelioma versus pleomorphic adenoma are discussed.
Topics: Adult; Humans; Myoepithelioma; Palatal Neoplasms
PubMed: 18059237
DOI: No ID Found