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Circulation Research Feb 1991
Topics: Animals; Dogs; Neurons, Afferent; Potassium Channels; Pressoreceptors; Pressure; Pulsatile Flow
PubMed: 1991360
DOI: 10.1161/01.res.68.2.619 -
Cleveland Clinic Journal of Medicine 1988
Topics: Cost-Benefit Analysis; Evaluation Studies as Topic; Humans; Hypotension, Orthostatic; Pressoreceptors
PubMed: 3147821
DOI: 10.3949/ccjm.55.6.499 -
Reviews of Physiology, Biochemistry and... 1986
Review
Topics: Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Humans; Pressoreceptors; Reflex
PubMed: 3541137
DOI: 10.1007/BFb0034497 -
Hypertension (Dallas, Tex. : 1979) Mar 1992
Topics: Aldosterone; Blood Pressure; Endothelium, Vascular; Forecasting; Humans; Pressoreceptors
PubMed: 1548052
DOI: 10.1161/01.hyp.19.3.278 -
Journal of Clinical Pharmacology Oct 1991Orthostatic dysfunction occurs after exposure to microgravity, and is not completely understood. The authors developed a device for stimulating carotid baroreceptors to... (Review)
Review
Orthostatic dysfunction occurs after exposure to microgravity, and is not completely understood. The authors developed a device for stimulating carotid baroreceptors to test the hypothesis that exposure to microgravity leads to impairment of arterial baroreflex mechanisms. Data obtained before and after two head-down bedrest studies and before and after brief Space Shuttle missions indicate that baroreceptor-cardiac reflex control is impaired by simulated or actual weightlessness. The authors speculate that arterial baroreflex derangements combine with blood volume reductions and increased venous compliance to provoke orthostatic hypotension after microgravity exposure. Altered baroreflex function after missions may result from autonomic neuronal plasticity that develops during missions secondary to changes of cardiopulmonary and arterial dimensions and consequent changes of autonomic sensory input profiles.
Topics: Autonomic Nervous System; Humans; Pressoreceptors; Weightlessness
PubMed: 1761726
DOI: 10.1002/j.1552-4604.1991.tb03655.x -
Trends in Neurosciences Dec 1989The changes in respiration and cardiovascular output seen during mammalian defensive behaviour are no longer considered to be the product of simple reflexes. Nuclei in... (Review)
Review
The changes in respiration and cardiovascular output seen during mammalian defensive behaviour are no longer considered to be the product of simple reflexes. Nuclei in the diencephalon (in particular, in the hypothalamus and amygdala) are involved in controlling defence reactions. In this article, K. M. Spyer describes the evidence illustrating the actions of these descending influences and discusses the potential for future modelling paradigms in relation to cardiovascular control.
Topics: Animals; Behavior; Brain; Cardiovascular Physiological Phenomena; Emotions; Humans; Neural Pathways; Pressoreceptors
PubMed: 2480666
DOI: 10.1016/0166-2236(89)90111-2 -
Cold Spring Harbor Symposia on... 1965
Topics: Animals; Bees; Cell Membrane; Crustacea; Electrophysiology; Pressoreceptors; Sensory Receptor Cells
PubMed: 5219506
DOI: 10.1101/sqb.1965.030.01.009 -
Journal of Pharmacological and... 2000Techniques are described for the intravenous, close intraarterial, or perivascular delivery of drugs in conscious or anaesthetized animals. Examples of the determination... (Review)
Review
Techniques are described for the intravenous, close intraarterial, or perivascular delivery of drugs in conscious or anaesthetized animals. Examples of the determination of pharmacodynamic parameters such as regional blood flow, large artery diameter, resistance, conductance, and blood pressure are given for conscious rabbits and anaesthetized dog preparations. An important issue is how to determine the direct vascular action of an injected drug in the light of rapid and powerful autonomic reflex buffering effects especially in healthy conscious animals. The methods of measurement of drug action on the baroreceptor-heart rate reflex and postural adaptation (90 degrees tilt) reflex in the conscious rabbit are explained. Finally, the changes to large and small artery morphology are explored in the rabbit hindlimb following conduit femoral artery ligation to induce arteriogenesis and angiogenesis. This work aims to highlight approaches to exploring drug action in vivo, a much neglected skill in the repertoire of the modern cardiovascular pharmacologist.
Topics: Animals; Blood Pressure; Blood Vessels; Heart Rate; Humans; Infusions, Intra-Arterial; Injections, Intravenous; Posture; Pressoreceptors; Reflex; Regional Blood Flow; Vascular Resistance
PubMed: 11325581
DOI: 10.1016/s1056-8719(00)00122-2 -
Nederlands Tijdschrift Voor Geneeskunde Feb 1995
Topics: Acceleration; Cardiovascular System; Eye Diseases; Hemorrhage; Humans; Intraocular Pressure; Pressoreceptors; Sports
PubMed: 7885505
DOI: No ID Found -
Brain Research Bulletin Jan 2000The caudal ventrolateral medulla (CVLM) plays a critical role in cardiovascular regulation. Convincing data now support the hypothesis that inhibition of... (Review)
Review
The caudal ventrolateral medulla (CVLM) plays a critical role in cardiovascular regulation. Convincing data now support the hypothesis that inhibition of sympathoexcitatory neurons in the rostral ventrolateral medulla (RVLM) by CVLM neurons constitutes the necessary inhibitory link in baroreceptor reflex mediated control of sympathetic vasomotor outflow. Inhibition or destruction of the CVLM produces severe acute hypertension, consistent with blockade of baroreceptor reflexes and withdrawal of inhibition of RVLM sympathoexcitatory neurons. However, other data indicate that the CVLM also tonically inhibits RVLM sympathoexcitatory neurons in a manner not driven by baroreceptor input. In some studies, inhibition of the CVLM results in an increase in arterial pressure (AP) without inhibiting baroreceptor reflexes, possibly reflecting baroreceptor-independent and baroreceptor-dependent sub-regions of the CVLM. Furthermore, in baroreceptor-denervated rats, inhibition of the CVLM still leads to large increases in AP. In addition, in spontaneously hypertensive rats (SHR) central processing of baroreceptor reflexes appears normal but CVLM-mediated inhibition of the RVLM seems to be attenuated, suggesting that it is specifically a baroreceptor-independent mechanism of cardiovascular regulation in SHR that is altered. Taken together, these findings support an important, tonic, baroreceptor-independent inhibition of RVLM sympathoexcitatory neurons exerted by the CVLM.
Topics: Animals; Baroreflex; Heart; Medulla Oblongata; Neural Pathways; Pressoreceptors; Rats
PubMed: 10709958
DOI: 10.1016/s0361-9230(99)00234-8