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International Journal of Legal Medicine May 2020Mongolian spots (MS) are congenital dermal conditions resulting from neural crest-derived melanocytes migration to the skin during embryogenesis. MS incidences are...
Mongolian spots (MS) are congenital dermal conditions resulting from neural crest-derived melanocytes migration to the skin during embryogenesis. MS incidences are highly variable in different populations. Morphologically, MS present as hyperpigmented maculae of varying size and form, ranging from round spots of 1 cm in diameter to extensive discolorations covering predominantly the lower back and buttocks. Due to their coloring, which is also dependent on the skin type, MS may mimic hematoma thus posing a challenge on the physician conducting examinations of children in cases of suspected child abuse. In the present study, MS incidences and distribution, as well as skin types, were documented in a collective of 253 children examined on the basis of suspected child abuse. From these data, a classification scheme was derived to document MS and to help identify cases with a need for recurrent examination for unambiguous interpretation of initial findings alongside the main decisive factors for re-examination such as general circumstances of the initial examination (e. g., experience of the examiner, lighting conditions) and given dermatological conditions of the patient (e. g., diaper rash).
Topics: Adolescent; Age Distribution; Child; Child Abuse; Child, Preschool; Ethnicity; Female; Humans; Incidence; Infant; Male; Mongolian Spot; Physical Examination; Prospective Studies; Skin Neoplasms
PubMed: 32166386
DOI: 10.1007/s00414-019-02208-9 -
Italian Journal of Dermatology and... Dec 2021
Topics: Cafe-au-Lait Spots; Humans; Mongolian Spot; Neurofibromatosis 1; Skin Neoplasms
PubMed: 32129589
DOI: 10.23736/S2784-8671.20.06538-4 -
Asian/Pacific Island Nursing Journal 2020In Mongolia, cardiovascular disease is the leading cause of death, and prevalence of hypertension is very high. The aim of this study was to investigate the association...
In Mongolia, cardiovascular disease is the leading cause of death, and prevalence of hypertension is very high. The aim of this study was to investigate the association between hypertension and sociodemographic factors and health-related behaviors among men in Darkhan-Uul Province, Mongolia. This cross-sectional study was conducted between November 2015 and January 2016. Men whose wives were pregnant with ≤ 20 weeks gestation and had attended antenatal health checkups at public health facilities were recruited in this study. The data were collected as part of a survey of pregnant women and their partners. Data were collected using self-administered questionnaires, anthropometry, and spot urine samples. A total of 224 men participated in the survey, and data from 209 participants were included in the analysis. Multiple logistic regression analysis showed that men with higher BMI had higher odds of hypertension than those with lower BMI (adjusted odds ratio [AOR]: 1.14, 95% CI: 1.03-1.26). Those with urinary cotinine > 100 ng/ml (smokers) had a lower risk of hypertension (AOR: 0.24, 95% CI: 0.09-0.67) compared to participants with urinary cotinine/ml (nonsmokers). This is the first study to investigate the association between hypertension and sociodemographic factors and health-related behaviors among men in Mongolia. Based on the findings of this study, clinicians responsible for public health in Mongolia should provide health education regarding the importance of weight control in preventing hypertension.
PubMed: 32055683
DOI: 10.31372/20190404.1067 -
Italian Journal of Dermatology and... Dec 2021
Topics: Female; Humans; Melanoma; Mongolian Spot; Nevus, Blue; Pregnancy; Skin Neoplasms
PubMed: 32041936
DOI: 10.23736/S2784-8671.19.06409-5 -
Clinics in Dermatology 2019Gray diseases are a group of skin disorders characterized mainly by gray discoloration with or without involving the mucous membranes and nails. These diseases may be...
Gray diseases are a group of skin disorders characterized mainly by gray discoloration with or without involving the mucous membranes and nails. These diseases may be hereditary or acquired. Some of the better-known hereditary entities are dermal melanocytosis, incontinentia pigmenti, hypomelanosis of Ito, hemochromatosis, ochronosis, and silvery hair syndrome. Acquired diseases with gray coloring include late-stage organ failure, lichen planus pigmentosus, erythema dyschromicum perstans, and drug reactions. The discoloration is due to either increased epidermal and or dermal melanin or dermal deposition of a chromogen or a combination of both. Investigations are directed to determining the underlying medical condition and a skin biopsy is usually unnecessary. Likewise, treatment is directed mainly toward the underlying medical disease. Although bleaching (lightening) agents may diminish the discoloration, better results may be obtained from using a Q-switched laser and intense pulsed light, either alone or in combination with topical agents.
Topics: Anti-Bacterial Agents; Color; Drug Eruptions; Hemochromatosis; Humans; Hyperpigmentation; Incontinentia Pigmenti; Metals, Heavy; Mongolian Spot; Mucous Membrane; Nail Diseases; Nevus of Ota; Ochronosis; Skin Neoplasms
PubMed: 31896405
DOI: 10.1016/j.clindermatol.2019.07.011 -
Pediatric Dermatology Sep 2019
Topics: Humans; Mongolian Spot; Skin Neoplasms
PubMed: 31529640
DOI: 10.1111/pde.13933 -
International Journal of Dermatology Dec 2019
Topics: Female; Humans; Infant, Newborn; Livedo Reticularis; Mongolian Spot; Neurocutaneous Syndromes; Port-Wine Stain; Skin Diseases, Vascular; Telangiectasis
PubMed: 31463930
DOI: 10.1111/ijd.14612 -
Pediatric Dermatology Sep 2019"Mongolian spot" is a term still commonly used today and found in many dermatology textbooks. This article examines historic literature to understand the social and...
"Mongolian spot" is a term still commonly used today and found in many dermatology textbooks. This article examines historic literature to understand the social and political climate at the time of its coining. By doing so, this article critically examines the choice of words in pediatric dermatology and how we can use medical terminology to gain the trust and respect of our patients.
Topics: History, 18th Century; History, 19th Century; Humans; Mongolian Spot; Skin Neoplasms
PubMed: 31141213
DOI: 10.1111/pde.13858 -
Journal of the European Academy of... Jun 2019Dermal melanocytoses (DMs) comprise a heterogeneous group of benign lesions, located on skin and mucous membranes, characterized by dendritic melanocytes in the dermis.... (Review)
Review
Dermal melanocytoses (DMs) comprise a heterogeneous group of benign lesions, located on skin and mucous membranes, characterized by dendritic melanocytes in the dermis. Although they share common histopathological features, some variants may present only as bluish or grey patches, some only as papules/nodules/plaques and others may show combination of all of these lesions. Despite the fact that blue naevus (BN) is typically characterized with papulonodular lesions, its variants may show all of the aforementioned presentations. Mongolian spot, naevus of Ota and naevus of Ito are patchy DMs distinguished by their specific localizations. Apart from these classical forms, many atypical variants without unique clinicopathological characteristics have been described in the literature making the nomenclature of DMs more complicated. However, congenital dermal melanocytosis and acquired dermal melanocytosis seem to be crucial umbrella terms that encompass all patchy DMs in atypical locations. Papules or subcutaneous nodules on patchy lesions and association of epidermal pigmentation presenting as brownish patches may be encountered as rare features of DMs. On the other hand, delayed-onset subcutaneous nodules may be typical presentations of melanoma in patchy DMs; therefore, they deserve special attention. Large plaque-type BN with subcutaneous cellular nodules is a newly described entity, harbouring clinical features of various DMs together and has a high risk of melanoma. The whole spectrum of dermal dendritic melanocytic proliferations is discussed including novelties and controversial issues.
Topics: Cell Proliferation; Humans; Melanocytes; Nevus, Blue; Skin; Skin Neoplasms
PubMed: 30767282
DOI: 10.1111/jdv.15492 -
Medicine Aug 2018Phacomatosis pigmentovascularis (PPV) is a rare syndrome characterized by capillary malformation and pigmentary nevus. Congenital chylous ascites (CCA) is also a rare...
RATIONALE
Phacomatosis pigmentovascularis (PPV) is a rare syndrome characterized by capillary malformation and pigmentary nevus. Congenital chylous ascites (CCA) is also a rare disease that results from maldevelopment of the lymphatic system. We report a case of a 5-month-old girl, who had both PPV and CCA.
PATIENT CONCERNS
A 5-month-old girl is reported, who presented extensive nevus flammeus and an aberrant Mongolian spot with congenital chylous ascites.
DIAGNOSES
The expression of extensive nevus flammeus and an aberrant Mongolian spot with congenital chylous ascites, that was diagnosed as type IIb phacomatosis pigmentovascularis.
INTERVENTIONS
Conservative treatment included administration of somatostatin, MCT-based diet or TPN with drainage of ascitic fluid. Surgery was taken into account after failed conservative treatments. Before surgery, it is necessary to locate the abnormal lymphatic vessels.
OUTCOMES
Conservative treatment and surgery sometimes functioned limitedly on CCA.
LESSONS
According to the classification system of ISSVA (the International Society for the Study of Vascular Anomalies), this case meet the classification of CLM included in combined vascular malformations. It is likely to there is a connection between these two congenital diseases.
Topics: Chylous Ascites; Female; Humans; Infant; Mongolian Spot; Neurocutaneous Syndromes; Skin Neoplasms
PubMed: 30142845
DOI: 10.1097/MD.0000000000012012