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Journal of Medical Primatology Apr 2020This study reports the pathological and microbiological findings of pneumonia in a Mico melanurus caused by Pasteurella canis, confirmed for molecular analyses. It...
This study reports the pathological and microbiological findings of pneumonia in a Mico melanurus caused by Pasteurella canis, confirmed for molecular analyses. It demonstrated the importance that wild species represent in the epidemiology of pasteurellosis in anthropic environments, when inserted into urban areas.
Topics: Animals; Callitrichinae; Monkey Diseases; Pasteurella; Pasteurella Infections; Pneumonia
PubMed: 31808160
DOI: 10.1111/jmp.12452 -
Revue Des Maladies Respiratoires Dec 2019
Topics: Acute Disease; Aged; Disease Progression; Female; Humans; Pasteurella; Pasteurella Infections; Pulmonary Disease, Chronic Obstructive
PubMed: 31727553
DOI: 10.1016/j.rmr.2019.10.003 -
Praxis Jun 2019Spontaneous Expulsion of a Necrotic Metatarsal Head from a Dorsal Foot Ulcer in Osteomyelitis Osteomyelitis of metatarsal bones is a dreaded complication of foot ulcers...
Spontaneous Expulsion of a Necrotic Metatarsal Head from a Dorsal Foot Ulcer in Osteomyelitis Osteomyelitis of metatarsal bones is a dreaded complication of foot ulcers of various etiologies, often resulting in amputation of part of the affected limb. In this article, a case is presented in which a spontaneous expulsion of the necrotic bone part occurred, after which the ulcer could heal completely.
Topics: Diabetic Foot; Foot Ulcer; Humans; Metatarsal Bones; Osteomyelitis
PubMed: 31185845
DOI: 10.1024/1661-8157/a003249 -
The Canadian Veterinary Journal = La... Jun 2019Infectious sacroiliitis has not been described in dogs. This retrospective case series describes the presentation, diagnostic imaging characteristics, and outcomes of 2...
Infectious sacroiliitis has not been described in dogs. This retrospective case series describes the presentation, diagnostic imaging characteristics, and outcomes of 2 canine patients with infectious sacroiliitis. Selection criteria included presentation with back pain from 2010 to 2017, diagnostic imaging of the sacroiliac joints, and short- and long-term response to antibiotic therapy. Medical records, and magnetic resonance imaging (MRI) were reviewed by a Board-certified veterinary radiologist, a neurologist, and a small animal intern. Two dogs met the inclusion criteria. Magnetic resonance imaging revealed unilaterally wide and irregular sacroiliac joint spaces, with juxta-articular soft tissue contrast enhancement and bone marrow edema. One patient had a communicating abscess of the psoas muscle, which cultured positive for Following treatment with pain relief medications and antibiotics, both patients made a complete clinical recovery, with no signs of lameness 2 to 4 weeks after cessation of treatment, and no lameness reported by the owner afterwards. Infectious sacroiliitis should be considered when dogs are presented with lumbosacral pain.
Topics: Animals; Communicable Diseases; Dog Diseases; Dogs; Magnetic Resonance Imaging; Pasteurella; Retrospective Studies; Sacroiliac Joint; Sacroiliitis
PubMed: 31156264
DOI: No ID Found -
Veterinary Microbiology Feb 2019Infective endocarditis, an infrequent clinical syndrome in dogs, is typically associated with nondescript clinical signs such as fever, malaise and loss of appetite....
Infective endocarditis, an infrequent clinical syndrome in dogs, is typically associated with nondescript clinical signs such as fever, malaise and loss of appetite. Although an uncommonly reported infection in dogs, Pasteurella canis is an emerging pathogen with increasing relevance in the human microbiology literature. The goal of this study is to detail the clinical presentation and microbiological findings associated with a novel causative agent of infective endocarditis in the dog. Diagnostic evaluation as well as conventional, automated and molecular microbiological methods are highlighted. The recent literature regarding P. canis and infective endocarditis in companion animals and humans is reviewed. Although an unusual etiologic agent of infective endocarditis, awareness of P. canis as a diagnostic possibility is crucial to accurate microbial surveillance.
Topics: Animals; Dog Diseases; Dogs; Endocarditis, Bacterial; Fatal Outcome; Male; Pasteurella; Pasteurella Infections
PubMed: 30642590
DOI: 10.1016/j.vetmic.2018.12.001 -
Respiratory Medicine Case Reports 2019, which colonizes upper respiratory and digestive tracts, is a leading cause of respiratory diseases in many host species. Here, we describe a case of pneumonia with...
, which colonizes upper respiratory and digestive tracts, is a leading cause of respiratory diseases in many host species. Here, we describe a case of pneumonia with hemoptysis. A 72-year-old female diagnosed with bronchiectasis with a 36-year history presented with a worsened infiltrative and granular shadow in the lower right lobe and lingular segment. Bronchial lavage fluid culturing suggested Pasteurella pneumonia. was confirmed by 16S rRNA sequencing. The patient was readmitted to our hospital because of hemoptysis, and she was treated successfully with antibiotic therapy. The possibility of infection must be considered in patients who own pets.
PubMed: 30510895
DOI: 10.1016/j.rmcr.2018.11.004 -
SAGE Open Medical Case Reports 2017The purpose of this article is to review the clinical features of pasteurellosis in a tertiary centre over a period of 4½ years. We have identified eight cases of and...
The purpose of this article is to review the clinical features of pasteurellosis in a tertiary centre over a period of 4½ years. We have identified eight cases of and one case of infection, with a large diversity of clinical pictures and outcomes. All patients were elderly and/or immunocompromised and 55.6% reported animal exposure. Soft tissue infections were the most prevalent (55.6%), followed by pneumonia (22.2%) and sepsis (22.2 %). All isolates were susceptible to beta-lactam antibiotics using in vitro sensitivity testing. The overall mortality was 33.3%, which occurred in patients with no evidence of animal contact.
PubMed: 29318015
DOI: 10.1177/2050313X17748286 -
IDCases 2017We describe a case of refractory keratitis that initially failed antimicrobial treatment but was successfully treated with a conjunctival flap followed by a penetrating...
INTRODUCTION
We describe a case of refractory keratitis that initially failed antimicrobial treatment but was successfully treated with a conjunctival flap followed by a penetrating keratoplasty.
CASE DISCUSSION
A 70-year-old male had persistent corneal edema related to previous herpes zoster keratouveitis with visual acuity of 20/400. An endothelial keratoplasty was performed with improvement in vision to 20/25. Several months after this surgery the patient developed a corneal infiltrate and cultures grew . The infection persisted despite topical treatment with broad spectrum fortified vancomycin, tobramycin and fluoroquinolones. A conjunctival flap combined with corneal cryotherapy was performed to help mitigate symptoms and to allow the ulcer to heal. A penetrating keratoplasty was done several months later.
DISCUSSION
The patient achieved pain relief immediately after the flap was placed. Medications were tapered off in the following few months after the procedure. A penetrating keratoplasty was performed 4 months later. The patient has remained almost entirely symptom free, and the graft remained clear one year after surgery.
CONCLUSIONS
A keratitis caused by that is resistant to medical therapy can be treated successfully with a conjunctival flap and cryotherapy followed by a penetrating keratoplasty.
PubMed: 28660128
DOI: 10.1016/j.idcr.2017.05.012 -
Journal of Clinical and Diagnostic... Feb 2017species are zoonotic bacterial pathogens implicated very infrequently in various human infections following animal bites or licks usually of dogs and cats. This case...
species are zoonotic bacterial pathogens implicated very infrequently in various human infections following animal bites or licks usually of dogs and cats. This case report described a rare clinical presentation of dacryocystitis caused by in a Human Immunodeficiency Virus (HIV) positive young male patient involved in caring of cattle. It advocates the utmost need of recognizing the wide clinical manifestation spectrum of even without prior penetrating injury. associated clinical infection is more extensive than had been thought previously especially in immunocompromised patient. Early accurate identification and evidence based anti-microbial therapy may prove crucial in preventing further potential complications.
PubMed: 28384864
DOI: 10.7860/JCDR/2017/22302.9388 -
Antimicrobial Agents and Chemotherapy Jun 2017Animal bite wounds affect more than 5 million Americans annually, resulting in 300,000 emergency department visits, 10,000 hospitalizations, and an untold number of...
Activity of Pexiganan and 10 Comparator Antimicrobials against 234 Isolates, Including 93 Pasteurella Species and 50 Anaerobic Bacterial Isolates Recovered from Animal Bite Wounds.
Animal bite wounds affect more than 5 million Americans annually, resulting in 300,000 emergency department visits, 10,000 hospitalizations, and an untold number of physician office visits. Various forms of topical therapy are empirically self-employed by many patients prior to seeking medical attention. Pexiganan, a 22-amino-acid synthetic cationic analogue of the peptide magainin II, acts by selectively damaging bacterial cell membranes. We determined the MICs for pexiganan and other antimicrobial agents often used for treatment of bite wounds. Most isolates were from U.S. patients, and ∼10% were from European and Canadian patients. The comparator antimicrobials studied were penicillin, amoxicillin-clavulanate, piperacillin-tazobactam, meropenem, clindamycin, doxycycline, moxifloxacin, ceftriaxone, linezolid, and metronidazole. The MICs of pexiganan were 32 μg/ml (against subsp. ), 16 μg/ml ( subsp. , , and ), 8 μg/ml (), 8 μg/ml (), 2 μg/ml (, , and group), 16 μg/ml (), 64 μg/ml (), 4 μg/ml (), 32 μg/ml (), and 64 μg/ml (). The concentration of pexiganan in the cream used was 8,000 μg/ml, more than 60 to 100 times the highest MIC obtained. Pexiganan exhibited a broad range of antimicrobial activity, showing potential for treating animal bite infections. A clinical trial seems warranted.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacteria, Anaerobic; Bites and Stings; Clindamycin; Doxycycline; Fluoroquinolones; Linezolid; Meropenem; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Pasteurella; Penicillanic Acid; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins
PubMed: 28373186
DOI: 10.1128/AAC.00246-17