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Journal of Ethnobiology and... Jun 2024The traditional knowledge in southern Yemen is rich in wild medicinal and food plants, which has been documented in our previous studies. In addition, other significant...
BACKGROUND
The traditional knowledge in southern Yemen is rich in wild medicinal and food plants, which has been documented in our previous studies. In addition, other significant and general traditional usage for the daily livelihood requirements of local people (beyond medicinal and food plant uses) has not been studied before and needs urgent documentation.
METHODS
Ethnobotanical data on of wild plants used by local people in southern Yemen were collected by oral questionnaire interviews. Most informants (n = 1020) were local elderly from 15 different localities in southern Yemen. The local names and non-medicinal and non-food uses of plants were identified and analyzed.
RESULTS
The ethnobotanical data resulted various traditional uses of 73 plant species distributed in 28 families. The most represented families were Fabaceae, Asteraceae and Malvaceae. The most growth forms were trees and shrubs. Seven main and common categories of traditional uses were determined and classified as handicraft, health aids, livestock husbandry and beekeeping, economic and commercial plant products, agriculture tools, construction timber and fuel. The most cited species were identified for Ziziphus spina-christi, Vachellia tortilis, Vachellia nilotica, Anisotes trisulcus, Dracaena hanningtonii (Sansevieria ehrenbergii) and Aerva javanica, which have multi-purpose values of traditional usage. Nine major traditional uses of local wild plants were recorded: handicraft, agriculture tools, products aid general health, economic products, construction timber, livestock husbandry, bee keeping, fuel and ornamental.
CONCLUSIONS
Despite the challenges on local traditional knowledge of wild plants, it still requested vital to many usages of traditional life and still have an economic value and heritage required of develop the daily livelihood level of the local people especially in rural areas. This includes the traditional uses of wild plants in handicraft skills, tools of agriculture, constructions. The importance of the continuity of traditional industries and their transmission to generations lies in the local population's reliance on local natural resources without relying on external resources in situations such as wars. This is the first study that contributes to documenting and analyzing the indigenous knowledge on traditional general usage of wild plants in southern Yemen.
Topics: Yemen; Ethnobotany; Humans; Plants, Medicinal; Male; Female; Plants, Edible; Middle Aged; Aged; Adult; Knowledge; Surveys and Questionnaires
PubMed: 38898489
DOI: 10.1186/s13002-024-00698-5 -
Seminars in Diagnostic Pathology Jul 2024
Review
Topics: Humans; Salivary Gland Neoplasms; Uncertainty; Diagnosis, Differential; Salivary Glands
PubMed: 38897822
DOI: 10.1053/j.semdp.2024.06.002 -
Protein Expression and Purification Jun 2024Tribolium castaneum, also known as the red flour beetle, is a polyphagous pest that seriously damages agricultural products, including stored and processed grains....
Tribolium castaneum, also known as the red flour beetle, is a polyphagous pest that seriously damages agricultural products, including stored and processed grains. Researchers have aimed to discover alternative pest control mechanisms that are less harmful to the ecosystem than those currently used. We conduct the purification and characterization of a protease inhibitor from C. plumieri seeds and an in vitro evaluation of its insecticidal potential against the insect pest T. castaneum. The trypsin inhibitor was isolated from C. plumieri seeds in a single-step DEAE-Sepharose column chromatography and had a molecular mass of 50 kDA. When analyzed for interaction with different proteolytic enzymes, the inhibitor exhibited specificity against trypsin and no activity against other serine proteases such as chymotrypsin and elastase-2. The isolated inhibitor was able to inhibit digestive enzymes of T. castaneum from extracts of the intestine of this insect. Therefore, we conclude that the new protease inhibitor, specific in tryptic inhibition, of protein nature from the seeds of C. plumieri was effective in inhibiting the digestive enzymes of T. castaneum and is a promising candidate in the ecological control of pests.
PubMed: 38897399
DOI: 10.1016/j.pep.2024.106534 -
Virus Research Jun 2024Epizootic haemorrhagic disease (EHD), caused by the EHD virus (EHDV), is a vector-borne viral disease transmitted through Culicoides biting midges. EHDV comprises seven...
Epizootic haemorrhagic disease (EHD), caused by the EHD virus (EHDV), is a vector-borne viral disease transmitted through Culicoides biting midges. EHDV comprises seven serotypes (1, 2, and 4-8), with EHDV-8 having recently emerged and spread in Europe over the last two years. Such event has raised concerns about the significant threat posed by EHDV-8 to livestock industry. In this study, an inactivated vaccine against EHDV-8 (vEHDV8-IZSAM) was developed. Safety and efficacy of the vaccine were evaluated in calves through clinical, serological, and virological monitoring following experimental challenge. The vaccine was proven safe, with only transient fever and localized reactions observed in a few animals, consistent with adjuvanted vaccine side effects. vEHDV8-IZSAM elicited a robust humoral response, as evidenced by the presence of neutralizing antibodies. After challenge with a virulent isolate, viraemia and clinical signs were evidenced in control animals but in none of the vaccinated animals. This study highlights the potential of vEHDV8-IZSAM as a safe and highly effective vaccine against EHDV-8 in cattle. It offers protection from clinical disease and effectively prevents viraemia. With the recent spread of EHDV-8 in European livestock, the use of an inactivated vaccine could be key in protecting animals from clinical disease and thus to mitigate the economic impact of the disease. Further investigations are warranted to assess the duration of the induced immunity and the applicability of this vaccine in real-world settings. Accordingly, joint efforts between public veterinary institutions and pharmaceutical companies are recommended to scale up vaccine production.
PubMed: 38897236
DOI: 10.1016/j.virusres.2024.199416 -
Frontiers in Public Health 2024Varicella, a highly contagious viral disease caused by the varicella-zoster virus (VZV), affects millions globally, with a higher prevalence among children. After the...
OBJECTIVE
Varicella, a highly contagious viral disease caused by the varicella-zoster virus (VZV), affects millions globally, with a higher prevalence among children. After the initial infection, VZV lies dormant in sensory ganglia and has the potential to reactivate much later, causing herpes zoster (HZ). Vaccination is one of the most effective methods to prevent varicella, and the two-dose varicella vaccine (VarV) regimen is widely used around the world. In China, the VarV has been included in the national immunization programme with a recommended single-dose regimen. This study aimed to compare the effectiveness of the two-dose vs. one-dose VarV regimen in children in Shanghai, China.
MATERIALS AND METHODS
A prospective cohort study was conducted in Shanghai, China, from September 2018 to December 2022. The study enrolled children aged 3-18 years who had received either the one-dose, two-dose, or 0-dose VarV regimen. Vaccination history, varicella infection status, and relevant variables, including demographic information (name, date of birth and sex) and medical history (clinical features of varicella and illness duration) were collected through medical record review and parental interviews.
RESULTS
A total of 3,838 children were included in the study, with 407 in the 0-dose regimen group, 2,107 in the one-dose regimen group and 1,324 in the two-dose regimen group. The corresponding incidence density in these groups was 0.13, 0.05 and 0.03 cases per 1,000 person-days, respectively. The adjusted vaccine effectiveness (VE) was 81.7% (95%CI: 59.3-91.8%) for the two-dose regimen and 60.3% (95%CI: 29.3-77.7%) for the one-dose regimen, compared to the 0-dose regimen. The two-dose VarV regimen showed a protective effectiveness of 47.6% (95%CI: 2.5-71.9%) compared to the one-dose VarV regimen.
CONCLUSION
This study provides evidence supporting the greater effectiveness of the two-dose VarV regimen in preventing varicella infection compared to the one-dose regimen.
Topics: Humans; Chickenpox Vaccine; China; Prospective Studies; Child; Chickenpox; Male; Female; Child, Preschool; Adolescent; Vaccination; Immunization Schedule; Herpes Zoster
PubMed: 38894987
DOI: 10.3389/fpubh.2024.1320407 -
Nutrients May 2024The consumption of protein-rich foods stimulates satiety more than other macronutrient-rich foods; however, the underlying mechanisms-of-action are not...
Examining the Direct and Indirect Effects of Postprandial Amino Acid Responses on Markers of Satiety following the Acute Consumption of Lean Beef-Rich Meals in Healthy Women with Overweight.
The consumption of protein-rich foods stimulates satiety more than other macronutrient-rich foods; however, the underlying mechanisms-of-action are not well-characterized. The objective of this study was to identify the direct and indirect effects of postprandial amino acid (AA) responses on satiety. Seventeen women (mean ± SEM, age: 33 ± 1 year; BMI: 27.8 ± 0.1 kg/m) consumed a eucaloric, plant-based diet containing two servings of lean beef/day (i.e., 7.5 oz (207 g)) for 7 days. During day 6, the participants completed a 12 h controlled-feeding, clinical testing day including repeated satiety questionnaires and blood sampling to assess pre- and postprandial plasma AAs, PYY, and GLP-1. Regression and mediation analyses were completed to assess AA predictors and hormonal mediators. Total plasma AAs explained 41.1% of the variance in perceived daily fullness ( < 0.001), 61.0% in PYY ( < 0.001), and 66.1% in GLP-1 ( < 0.001) concentrations, respectively. Several individual AAs significantly predicted fluctuations in daily fullness, PYY, and GLP-1. In completing mediation analyses, the effect of plasma leucine on daily fullness was fully mediated by circulating PYY concentrations (indirect effect = B: 0.09 [Boot 95% CI: 0.032, 0.17]) as no leucine-fullness direct effect was observed. No other mediators were identified. Although a number of circulating AAs predict satiety, leucine was found to do so through changes in PYY concentrations in middle-aged women.
Topics: Humans; Female; Adult; Postprandial Period; Amino Acids; Red Meat; Peptide YY; Satiation; Overweight; Glucagon-Like Peptide 1; Biomarkers; Meals; Animals; Cattle; Satiety Response
PubMed: 38892651
DOI: 10.3390/nu16111718 -
Nutrients May 2024Food marketing targeting children influences their choices and dietary habits, and mainly promotes food high in fat, sugar, and salt as well as ultra-processed food. The...
Food marketing targeting children influences their choices and dietary habits, and mainly promotes food high in fat, sugar, and salt as well as ultra-processed food. The aim of this study was to assess the nutritional quality of food and beverages marketed to children over the age of 3 and available on the Swiss market. Products with at least one marketing technique targeting children on the packaging were selected from five food store chains. Three criteria to assess nutritional quality were used: (1) nutritional composition (using the Nutri-Score), (2) degree of processing (NOVA classification), and (3) compliance with the World Health Organization (WHO) Nutrient Profile Model (NPM). A total of 735 products were found and analyzed. The most common marketing techniques used were childish names/fonts (46.9%), special characters (39.6%), and children's drawings (31.3%). Most products had a Nutri-Score of D or E (58.0%) and were ultra-processed (91.8%). Only 10.2% of products displayed the Nutri-Score. The least processed products generally had a better Nutri-Score ( < 0.001). Most products (92.8%) did not meet the criteria of the WHO NPM. Products that met the WHO NPM criteria, organic products, and products with a nutritional claim generally had a better Nutri-Score and were less processed (p < 0.05). Pre-packaged foods and beverages marketed to children in the Swiss market were mostly of poor nutritional quality. Public health measures should be adopted to improve the nutritional quality of foods marketed to children in Switzerland and restrict the marketing of unhealthy foods to children.
Topics: Switzerland; Nutritive Value; Humans; Child; Marketing; Food Packaging; Child, Preschool; Surveys and Questionnaires
PubMed: 38892589
DOI: 10.3390/nu16111656 -
Medical Science Educator Jun 2024To promote evidence-based practice, medical schools offer students opportunities to undertake either elective or mandatory research projects. One important measure of...
To promote evidence-based practice, medical schools offer students opportunities to undertake either elective or mandatory research projects. One important measure of the research program success is student publication rates. In 2006, UNSW Medicine implemented a mandatory research program in the 4th year of the undergraduate medical education program. This study identified student publication rates and explored student and supervisor experiences with the publication process. A retrospective audit of student publications from the 2007, 2011, and 2015 cohorts was undertaken to look at trends over time. Data collected included type of publication and study methodology. Semi-structured interviews were conducted with a sample of undergraduate students ( = 11), medical graduates ( = 14), and supervisors ( = 25) and analysed thematically. Student publication rates increased significantly ( = 0.002) from 28% in 2007 to 50.2% in 2015. Students able to negotiate their own project were more likely to publish ( = 0.02). Students reported personal affirmation and development of research skills from publishing their research findings, while graduates noted improved career opportunities. Supervisors expected students to publish but identified the time to publications and student motivation as key factors in achieving publication(s). A high publication rate is possible in a mandatory research program where students can negotiate their own topic and are given protected time. Publications happen after the research project has finished. Critical factors in successful publication include supervisor support and student motivation. Given the importance of the supervisor's role, staff development and faculty support to train and develop a body of skilled supervisors is required.
PubMed: 38887404
DOI: 10.1007/s40670-024-02029-5 -
BMC Public Health Jun 2024Structural and behavioral interventions to manage work-related stress are effective in employees. Nonetheless, they have been implemented insufficiently, particularly in...
BACKGROUND
Structural and behavioral interventions to manage work-related stress are effective in employees. Nonetheless, they have been implemented insufficiently, particularly in micro- and small-sized enterprises (MSE). Main barriers include a lack of knowledge and limited resources, which could potentially be overcome with simplified web-based alternatives for occupational stress prevention. However, there is a lack of implementation research about web-based prevention in realistic settings of MSE.
OBJECTIVE
The aim of this study is to evaluate the implementation process and success of an integrated web-based platform for occupational stress prevention ("System P") and to identify potential barriers for its uptake and use in MSE in Germany.
METHODS
This study with a mixed-methods approach investigates eight process-related outcomes in a quantitative part I (adoption, reach, penetration, fidelity/dose, costs, acceptability) and a qualitative part II (acceptability, appropriateness and feasibility). Part I has a pre-post design with two measurements (6 months apart) with 98 individual participants and part II consists of 12 semi-structured interviews with managers and intercorporate stakeholders.
RESULTS
Part I revealed shortcomings in the implementation process. Adoption/Reach: Despite extensive marketing efforts, less than 1% of the contacted MSE responded to the offer of System P. A total of 40 MSE registered, 24 of which, characterized by good psychosocial safety climate, adopted System P. Penetration: Within these 24 MSE, 15% of the employees used the system. Fidelity/Dose: 11 MSE started a psychosocial risk-assessment (PRA), and no MSE finished it. The stress-management training (SMT) was started by 25 users and completed by 8.
COSTS
The use of System P was free of charge, but the time required to engage with was an indirect cost. Part II added insights on the perception of the web-based intervention: Acceptance of System P by users and stakeholders was good and it was assessed as appropriate for MSE. Results for feasibility were mixed.
CONCLUSIONS
Although System P was generally perceived as useful and appropriate, only a small number of contacted MSE implemented it as intended. Prior experience and sensitivity for occupational (stress) prevention were mentioned as key facilitators, while (perceived) indirect costs were a key barrier. Enabling MSE to independently manage stress prevention online did not result in successful implementation. Increasing external support could be a solution. ⁺ FULL PROJECT NAME: "PragmatiKK - Pragmatische Lösungen für die Implementation von Maßnahmen zur Stressprävention in Kleinst- und Kleinbetrieben" (= Pragmatic solutions for the implementation of stress prevention interventions in micro and small-sized enterprises).
TRIAL REGISTRATION
German Register of Clinical Studies (DRKS) DRKS00026154, date of registration 2021-09-16.
Topics: Humans; Germany; Occupational Stress; Female; Male; Adult; Middle Aged; Small Business; Internet; Program Evaluation; Internet-Based Intervention; Qualitative Research
PubMed: 38886711
DOI: 10.1186/s12889-024-19102-8 -
Australian and New Zealand Journal of... Jun 2024To assess how Australian infant and toddler foods compare to a nutrient and promotion profile model (NPPM) developed by the World Health Organization to support the...
OBJECTIVE
To assess how Australian infant and toddler foods compare to a nutrient and promotion profile model (NPPM) developed by the World Health Organization to support the appropriate promotion of commercial food products for children aged 6-36 months.
METHODS
A cross-sectional audit of infant and toddler foods found at three major Australian supermarkets was conducted in September/October 2022. Using nutrition and promotional data extracted from the packaging, products were classified according to NPPM categories and assessed against relevant compositional, front-of-pack labelling and promotional requirements.
RESULTS
Of 330 eligible products identified, just 28% met all NPPM compositional requirements. Toddler foods were less compliant than infant foods overall (18% vs. 31%; p=0.021), and for specific nutrients such as sodium (75% vs. 89%; p=0.003). No products met all NPPM front-of-pack labelling/promotional requirements. Only two-thirds and two-fifths of products were compliant with product name and ingredient list requirements, respectively.
CONCLUSION
Australian infant and toddler foods do not fully comply with the NPPM requirements. While toddler foods performed comparatively worse in terms of their nutritional adequacy, there is considerable scope to improve the nutrient profile of both infant and toddler foods.
IMPLICATIONS FOR PUBLIC HEALTH
To better support young children's health and development, the introduction of mandatory nutrition standards for Australian toddler foods, and the improvement of nutrition standards for Australian infant foods, in line with the NPPM, is needed. To be most effective, these should be combined with regulations for the labelling and promotion of these foods in line with the NPPM.
Topics: Humans; Australia; Infant; Cross-Sectional Studies; Food Labeling; Child, Preschool; Nutritive Value; Infant Food; Nutrition Policy; Male; Female; Supermarkets
PubMed: 38886145
DOI: 10.1016/j.anzjph.2024.100158