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Journal of the European Academy of... Sep 2021Descriptions of cutaneous findings associated with COVID-19 have not been consistently accompanied by histopathology or confirmatory testing for SARS-CoV-2.
BACKGROUND
Descriptions of cutaneous findings associated with COVID-19 have not been consistently accompanied by histopathology or confirmatory testing for SARS-CoV-2.
OBJECTIVE
To describe and classify the cutaneous findings with supporting histopathology of confirmed COVID-19 inpatients.
METHODS
We included consecutive inpatients with a confirmed diagnosis of COVID-19 for whom a dermatology consult was requested. A skin biopsy was performed in all cases. Skin findings were classified as being compatible with a cutaneous manifestation of COVID-19 or as representing a distinct clinical entity.
RESULTS
Twenty-eight patients were studied in whom thirty-one dermatologic diagnoses were made. Twenty-two of the dermatoses were compatible with a cutaneous manifestation of COVID-19; nine entities were not associated with infection by SARS-CoV-2. The most common COVID-19-associated pattern was an exanthematous presentation. In four patients, a new pattern was observed, characterized by discrete papules with varied histopathological findings including a case of neutrophilic eccrine hidradenitis. No cases of pernio-like lesions were identified. Skin findings not associated with COVID-19 represented 29% of diagnoses and included Malassezia folliculitis, tinea, miliaria and contact dermatitis.
LIMITATIONS
There is no gold-standard test to distinguish between viral exanthems and drug reactions.
CONCLUSION
A histopathological study is critical before attributing skin findings to a manifestation of COVID-19.
Topics: COVID-19; Chilblains; Humans; SARS-CoV-2; Skin; Skin Diseases
PubMed: 34013600
DOI: 10.1111/jdv.17381 -
JAAD Case Reports May 2021
PubMed: 33898685
DOI: 10.1016/j.jdcr.2021.02.003 -
Acta Bio-medica : Atenei Parmensis Nov 2020Skin disorders are very common in children. Wide spectrum of skin disorders is seen among children. The spectrum of skin disorders seen in children vary from region to...
BACKGROUND
Skin disorders are very common in children. Wide spectrum of skin disorders is seen among children. The spectrum of skin disorders seen in children vary from region to region.
AIM OF THE WORK
The study is aimed to determine the pattern of skin disorders among children in Pediatric dermatology clinic of Murtala Muhammad Specialist Hospital, Kano, Nigeria. Methods: It was a descriptive cross-sectional study. Subjects were consecutively recruited. Using a semi-structured questionnaire, demographic history of the subjects and history of skin disorders were obtained from all the subjects and detailed physical examination was carried out with particular emphasis on skin lesion examination after obtaining an informed consent. Ethical clearance was obtained from Ethical committee of the hospital. Data obtained was analyzed using SPSS version 24.
RESULTS
A total of 338 subjects were recruited. One hundred and seventy-three (51.2%) were males and 165 (48.8%) were females. There were 35 specific types of skin disorders observed. Infections and infestations were the commonest category of skin disorders seen among 47% of the children followed by inflammatory skin disorders observed among 36.9% of the subjects. Tinea capitis was the commonest type of skin disorder observed among 15.5% of the subjects followed by atopic eczema (13.0%). Tinea capitis was significantly commoner among male children aged 6-10 years (p<0.01) and Miliaria was significantly commoner among children aged less than 2years (p=0.04).
CONCLUSION
Wide spectrum of skin disorders was seen among children in this environment and infections and infestations were the commonest category of skin disorders seen.
Topics: Ambulatory Care Facilities; Child; Child, Preschool; Cross-Sectional Studies; Female; Hospitals; Humans; Male; Nigeria; Skin Diseases
PubMed: 33525278
DOI: 10.23750/abm.v91i4.8727 -
Dermatologic Therapy Mar 2021
Topics: Health Personnel; Humans; Masks; Miliaria; N95 Respirators
PubMed: 33492777
DOI: 10.1111/dth.14809 -
Dermatologic Therapy Jan 2021Prevalence of dermatological manifestations of coronavirus disease 2019 (COVID-19) is estimated between 0.25% and 3% in children and adolescents. In this review article,... (Review)
Review
Prevalence of dermatological manifestations of coronavirus disease 2019 (COVID-19) is estimated between 0.25% and 3% in children and adolescents. In this review article, we decided to describe the cutaneous and histopathological manifestations of COVID-19 infection in pediatrics. We searched published articles in PubMed database for key words of "children" or "pediatric" and "cutaneous" or "dermatology" or "skin" and "COVID-19" or "SARS-CoV-2" or "Coronavirus disease 2019" in abstract or title from December of 2019 until September 2020. Finally, 38 articles were selected. The majority of patients were between 11 and 17 years old with predominantly male gender. Most of the patients were either asymptomatic or had a few general symptoms. The latency time from appearance of general symptoms to cutaneous ones was between 1 day and weeks. Skin lesions faded between 3 and 88 days without any sequelae, spontaneously or with either topical or systemic corticosteroids. Skin manifestations were chilblain-like (pseudochilblain), erythema multiforme-like, dactylitis, acral erythema, acute urticaria, livedo reticularis, mottling, acro-ischemia, generalized maculopapular lesions, eyelid dermatitis, miliaria-like, varicelliform lesions, and petechiae and/or purpura. Kawa-COVID-19 patients were presented more frequently with cardiogenic shock, neurological symptoms, lymphocytopenia, and thrombocytopenia as compared to classic Kawasaki's disease. Furthermore, more number of cases were resistant to the first-line treatments.
Topics: Adolescent; COVID-19; Child; Humans; Pediatrics; SARS-CoV-2; Skin; Skin Diseases
PubMed: 33210417
DOI: 10.1111/dth.14554 -
Actas Dermo-sifiliograficas Oct 2020
Topics: Child; Fox-Fordyce Disease; Humans
PubMed: 32563546
DOI: 10.1016/j.ad.2019.03.016 -
Journal of the European Academy of... Aug 2020
Topics: Betacoronavirus; COVID-19; Coronavirus Infections; Face; Female; Humans; Miliaria; Pandemics; Pneumonia, Viral; SARS-CoV-2; Ventilators, Mechanical
PubMed: 32386442
DOI: 10.1111/jdv.16624 -
Indian Dermatology Online Journal 2019Sweat dermatitis is a peculiar kind of irritant inflammatory dermatoses occurring due to prolonged exposure of retained sweat over the skin. It is commonly seen in hot...
Sweat dermatitis is a peculiar kind of irritant inflammatory dermatoses occurring due to prolonged exposure of retained sweat over the skin. It is commonly seen in hot and dry climates like tropics during summer months due to thermal stress. Typically, parchment paper or cellophane paper like scaling is seen over occluded areas of back, shoulder, and other areas. Here we have reported a varied presentation of sweat dermatitis in the form of its coexistence with miliaria rubra (impending to thermal burn). Further we have also observed co existing pityriasis versicolor and sweat dermatitis where the former has prevented the development of latter. Till date there is very little discussion on this condition, so we have tried to provide a concise review about sweat dermatitis along with its classical to atypical presentation with special emphasis on dermoscopy.
PubMed: 31807452
DOI: 10.4103/idoj.IDOJ_5_19 -
Granulomatous Variant of Giant Centrifugal Miliaria Profunda in a Hypothyroid Infant: A Case Report.Indian Dermatology Online Journal 2019The miliarias are a clinically heterogeneous group of diseases which occur when the free flow of eccrine sweat to the skin surface is impeded. Miliaria profunda is a...
The miliarias are a clinically heterogeneous group of diseases which occur when the free flow of eccrine sweat to the skin surface is impeded. Miliaria profunda is a variant with obstruction of the duct at or below the level of dermoepidermal junction. The giant centrifugal variant of miliaria profunda has been described in the past at the sites of occlusive tapes and in febrile patients. Thyroid hormone has a regulatory effect on the skin and its appendages and an association of hypothyroidism with this variant of miliaria profunda has not been described in the past. We report a case of giant centrifugal miliaria profunda in an infant with congenital hypothyroidism.
PubMed: 31544077
DOI: 10.4103/idoj.IDOJ_422_18 -
JAAD Case Reports Sep 2019
PubMed: 31516988
DOI: 10.1016/j.jdcr.2019.04.024