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Anais Brasileiros de Dermatologia Apr 2016The neonatal period comprises the first four weeks of life. It is a period of adaptation where the skin often presents several changes: transient lesions, resulting from...
The neonatal period comprises the first four weeks of life. It is a period of adaptation where the skin often presents several changes: transient lesions, resulting from a physiological response, others as a consequence of transient diseases and some as markers of severe disorders. The presence of pustules in the skin of the newborn is always a reason for the family and for the assisting doctor to be worried, since the newborn is especially vulnerable to bacterial, viral or fungal infection. However, the majority of neonatal skin pustules is not infectious, comprising the benign neonatal pustulosis. Benign neonatal pustuloses are a group of clinical disease characterized by pustular eruptions in which a contagious agent is not responsible for its etiology. The most common ones are erythema toxicum neonatorum, the transient neonatal pustular melanosis and the benign cephalic pustulosis. These dermatoses are usually benign, asymptomatic and self-limited. It is important that the dermatologist and the neonatologist can identify benign and transient lesions, those caused by genodermatoses, and especially differentiate between neonates with systemic involvement from those with benign skin lesions, avoiding unnecessary diagnostic tests and worries.
Topics: Diagnosis, Differential; Erythema; Female; Humans; Infant, Newborn; Male; Melanosis; Miliaria; Skin; Skin Diseases, Vesiculobullous
PubMed: 27192509
DOI: 10.1590/abd1806-4841.20164285 -
Indian Journal of Sexually Transmitted... 2016Fox-Fordyce disease is a rare, chronic skin disorder which affects the apocrine areas. This disease is due to the obstruction of the apocrine sweat duct. Extragenital...
Fox-Fordyce disease is a rare, chronic skin disorder which affects the apocrine areas. This disease is due to the obstruction of the apocrine sweat duct. Extragenital regions are commonly affected than the genital region. We, herein, report a case of Fox-Fordyce in a female, with onset in the fifth decade and involving only the genital region.
PubMed: 27190415
DOI: 10.4103/0253-7184.180293 -
International Wound Journal Oct 2016Fox-Fordyce disease (FFD) is a rare chronic disorder characterised by persistent inflammation because of the obstruction of apocrine sweat glands, which is a key factor...
Fox-Fordyce disease (FFD) is a rare chronic disorder characterised by persistent inflammation because of the obstruction of apocrine sweat glands, which is a key factor of pathogenesis. The treatment of FFD is known to be difficult, and the modalities of treatment have not yet been widely studied. We report the successful treatment of a case of bilateral areolar FFD by a combination of surgical excision and 1550-nm fractionated erbium glass laser in an 18-year-old woman. The patient presented with a bilateral areolar eruption of multiple, severely pruritic, 3-4 mm skin- to grey-coloured folliculocentric dome-shaped papules. The initial treatment plan was for bilateral surgical excision of the larger and more highly elevated papules via circumferential dermal excision, which was intended to maintain the areolar contour and minimise distortion. A 1550-nm fractional erbium glass laser was then used to control the remnant lesions. The patient was recurrence-free at 14 months after the final laser treatment, and she was fully satisfied with the treatment results.
Topics: Adolescent; Erbium; Female; Fox-Fordyce Disease; Glass; Humans; Laser Therapy; Nipples; Treatment Outcome
PubMed: 27072751
DOI: 10.1111/iwj.12586 -
JAAD Case Reports Jan 2016
PubMed: 27051811
DOI: 10.1016/j.jdcr.2015.09.021 -
BMJ Case Reports Nov 2015
Topics: Adolescent; Adult; Antineoplastic Agents; Febrile Neutropenia; Humans; Male; Miliaria; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tropical Climate
PubMed: 26611484
DOI: 10.1136/bcr-2015-212231 -
The American Journal of Dermatopathology Mar 2016Milia en plaque (MEP) is an uncommon disorder characterized by an erythematous plaque containing numerous milia. The pathogenesis of MEP is not clear. The authors report...
Milia en plaque (MEP) is an uncommon disorder characterized by an erythematous plaque containing numerous milia. The pathogenesis of MEP is not clear. The authors report a man with an erythematous plaque on the right retroauricular area, containing numerous white-yellow cysts varying in size. Histological examination showed that multiple cystic structures at various levels of the dermis that were lined by stratified squamous epithelium and contained keratinous material-these findings were consistent with the diagnosis of multiple milia. In addition to epidermal cysts, however, the lesion consisted of a branched proliferation of pale-staining keratinocytes lined with basal keratinocytes budding from the overlying epidermis. Moreover, some cysts were formed within the branched epithelial proliferation, had thicker cyst walls than the ordinary milium, or had irregular or branched projections toward the surrounding dermis. From these findings, the authors conclude that MEP is a distinct follicular hamartoma with cystic trichoepitheliomatous features.
Topics: Adult; Epidermal Cyst; Hamartoma; Humans; Male; Miliaria; Skin Diseases
PubMed: 26381115
DOI: 10.1097/DAD.0000000000000445 -
Indian Journal of Critical Care... Aug 2015In this summer season (May-June 2014) most of the days temperature was more than 40°C. Our hospital is surrounded by huge slums area. The population which is low in... (Review)
Review
In this summer season (May-June 2014) most of the days temperature was more than 40°C. Our hospital is surrounded by huge slums area. The population which is low in socioeconomic status used to work in such high temperature for more than 8 h daily. Hence, they are very prone to develop heat injuries in the form of heat edema, heat tetany, heat syncope, heat cramps, miliaria rubra, heat exhaustion, and heatstroke. Again it is compulsory to upgrade our knowledge on this life threatening condition.
PubMed: 26321809
DOI: 10.4103/0972-5229.162470 -
Journal of Clinical Research in... Jun 2015Pseudohypoaldosteronism (PHA) is defined as a state of resistance to aldosterone, a hormone crucial for electrolyte equilibrium. The genetically transmitted type of PHA...
Pseudohypoaldosteronism (PHA) is defined as a state of resistance to aldosterone, a hormone crucial for electrolyte equilibrium. The genetically transmitted type of PHA is primary hypoaldosteronism. Secondary hypoaldosteronism develops as a result of hydronephrosis or hydroureter. PHA patients suffer from severe hyponatremia and a severe clinical condition due to severe loss of salt can be encountered in the neonatal period. Dermal findings in the form of miliaria rubra can also develop in these patients. With the loss of salt, abnormal accumulation of sebum in the eye due to a defect in the sodium channels can also occur. In this paper, a case of PHA in a newborn showing typical dermatological and ophthalmological findings is presented.
Topics: Eye; Female; Fluid Therapy; Humans; Hydronephrosis; Infant, Newborn; Polyuria; Pseudohypoaldosteronism; Sebum; Skin; Sodium Channels
PubMed: 26316441
DOI: 10.4274/jcrpe.1740 -
Indian Journal of Dermatology 2015Neonatal pustular eruption is a group of disorders characterized by various forms of pustulosis seen in first 4 weeks of life. Its presentation is often similar with... (Review)
Review
Neonatal pustular eruption is a group of disorders characterized by various forms of pustulosis seen in first 4 weeks of life. Its presentation is often similar with some subtle differences, which can be further established by few simple laboratory aids, to arrive at a definite diagnosis. Given their ubiquitous presentation, it is sometimes difficult to differentiate among self-limiting, noninfectious, pustular dermatosis such as erythema toxicum neonatorum, transient neonatal pustular melanosis, miliaria pustulosa, etc., and potentially life threatening infections such as herpes simplex virus and varicella zoster virus infections. This review article tries to address the chronological, clinical, morphological, and histological differences among the various pustular eruptions in a newborn, in order to make it easier for a practicing dermatologist to diagnose and treat these similar looking but different entities of pustulation with a clear demarcation between the physiological benign pustular rashes and the infectious pustular lesions.
PubMed: 25814724
DOI: 10.4103/0019-5154.152558 -
Indian Journal of Dermatology,... 2015
Topics: Acneiform Eruptions; Acrodermatitis; Angiofibroma; Asteraceae; Dermatitis, Allergic Contact; Fabry Disease; Facial Dermatoses; Facial Neoplasms; Fox-Fordyce Disease; HIV Infections; Humans; Interferons; Protein Kinase Inhibitors; Skin Diseases, Vesiculobullous; TOR Serine-Threonine Kinases; Terminology as Topic; Tuberous Sclerosis; Urticaria; Waxes; Xeroderma Pigmentosum; Zinc
PubMed: 25566927
DOI: 10.4103/0378-6323.148618