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Environmental Research Dec 2023Both pesticides and high magnetic fields are suspected to be childhood leukemia risk factors. Pesticides are utilized at commercial plant nurseries, which sometimes...
BACKGROUND
Both pesticides and high magnetic fields are suspected to be childhood leukemia risk factors. Pesticides are utilized at commercial plant nurseries, which sometimes occupy the areas underneath high-voltage powerlines.
OBJECTIVES
To evaluate whether potential pesticide exposures (intended use, chemical class, active ingredient) utilized at plant nurseries act as an independent childhood leukemia risk factor or as a confounder for proximity to, or magnetic fields exposure from, high-voltage powerlines.
METHODS
We conducted a state-wide records-based case-control study for California with 5788 childhood leukemia cases and 5788 controls that examined specific pesticide use, magnetic field exposures and distances to both powerlines and plant nurseries. Exposure assessment incorporated geographic information systems, aerial satellite images, and other historical information.
RESULTS
Childhood leukemia risk was potentially elevated for several active pesticide ingredients: permethrin (odds ratio (OR) 1.49, 95% confidence interval (CI) (0.83-2.67), chlorpyrifos (OR 1.29, 95% CI 0.89-1.87), dimethoate (OR 1.79, 95% CI 0.85-3.76), mancozeb (OR 1.41, 95% CI 0.85-2.33), oxyfluorfen (OR 1.41, 95% CI 0.75-2.66), oryzalin (OR 1.60, 95% CI 0.97-2.63), and pendimethalin (OR 1.82, 95% CI 0.81-2.25). Rodenticide (OR 1.42, 95% CI 0.78-2.56) and molluscicide (OR 1.22, 95% CI 0.82-1.81) exposure also presented potentially elevated childhood leukemia risks. Childhood leukemia associations with calculated fields or powerline proximity did not materially change after adjusting for pesticide exposure. Childhood leukemia risks with powerline proximity remained similar when pesticide exposures were excluded.
DISCUSSION
Pesticide exposure may be an independent childhood leukemia risk factor. Childhood leukemia risks for powerline proximity and magnetic fields exposure were not explained by pesticide exposure.
Topics: Humans; Child; Electromagnetic Fields; Pesticides; Environmental Exposure; Case-Control Studies; Leukemia; Risk Factors
PubMed: 37598846
DOI: 10.1016/j.envres.2023.116899 -
Scientific Reports Aug 2023Pollinators in agricultural landscapes are facing global decline and the main pressures include food scarcity and pesticide usage. Intensive agricultural landscapes may...
Pollinators in agricultural landscapes are facing global decline and the main pressures include food scarcity and pesticide usage. Intensive agricultural landscapes may provide important food resources for wild pollinators via mass flowering crops. However, these are monofloral, short-term, and may contain pesticide residues. We explored how the landscape composition with a different proportion of oilseed rape (6-65%) around Osmia bicornis nests affects floral diversity, contamination with pesticides, and energetic value of provisions collected by this species of wild bees as food for their offspring. Altogether, the bees collected pollen from 28 plant taxa (6-15 per nest) and provisions were dominated by Brassica napus (6.0-54.2%, median 44.4%, 12 nests), Quercus sp. (1.2-19.4%, median 5.2%, 12 nests), Ranunculus sp. (0.4-42.7%, median 4.7%, 12 nests), Poaceae (1.2-59.9%, median 5.8%, 11 nests) and Acer sp. (0.6-42%, median 18.0%, 8 nests). Residues of 12 pesticides were found in provisions, with acetamiprid, azoxystrobin, boscalid, and dimethoate being the most frequently detected at concentrations up to 1.2, 198.4, 16.9 and 17.8 ng/g (median 0.3, 10.6, 11.3, 4.4 ng/g), respectively. Floral diversity and energetic value of provisions, but not the Pesticide Risk Index depended on landscape structure. Moreover, pollen diversity decreased, and energetic value increased with landscape diversity. Thus, even a structurally simple landscape may provide diverse food for O. bicornis if the nest is located close to a single but resource-diverse patch. Both B. napus and non-crop pollen were correlated with pesticide concentrations.
Topics: Bees; Animals; Pesticide Residues; Brassica napus; Pesticides; Acer; Crops, Agricultural
PubMed: 37591888
DOI: 10.1038/s41598-023-39950-5 -
Chemosphere Nov 2023The competition impact and feedstock type on the removal of water pesticides using biochar have not yet been sufficiently investigated. Therefore, here we investigated...
The competition impact and feedstock type on the removal of water pesticides using biochar have not yet been sufficiently investigated. Therefore, here we investigated the potentiality of three different biochars (BCs) derived from rice husk (RHB), date pit (DPB), and sugarcane bagasse (SBB) biowastes for the simultaneous removal of ten pesticides from water in a competitive adsorption system. The BCs structural characterization and morphology were investigated by XRD, FTIR spectroscopy and SEM analysis. The potential adsorption mechanisms have been investigated using various isothermal and kinetic models. RHB showed the highest removal percentages (61% for atrazine/dimethoate and 97.6% for diuron/chlorfenvinphos) followed by DPB (56% for atrazine/dimethoate and 95.4% for diuron/chlorpyrifos) and then SBB (60.8% for atrazine/dimethoate and 90.8% for chlorpyrifos/malathion). The higher adsorption capacity of RHB and DPB than SBB can be due to their high total pore volume and specific surface area (SSA). Langmuir model described well the sorption data (R = 0.99). Adsorption equilibrium was achieved after 60 min for RHB, and 120 min for both DPB and SBB. The optimum adsorbent dose (g/L) was 10 for RHB and 4 for DPB and SBB. The removal efficiency of pesticides was enhanced by decreasing pH from 9 to 5 by RHB and to 3 by DPB and SBB. XRD and FTIR spectroscopy confirmed that BCs contain some active adsorption groups and metal oxides such as MgO, SiO, AlO, CaO, and TiO that can play an effective role in the pesticides sorption. BET-N adsorption analysis demonstrated that the BC pore size contributes significantly to pesticide adsorption. These findings indicate that RHB, DPB, and SBB have ability for adsorption of water pesticides even under acidic conditions. Therefore, the rice husk, date pit, and sugarcane bagasse biowastes could be pyrolyzed and reused as effective and low-cost sorbents for elimination of hazardous substances such as pesticides in the aqueous environments.
Topics: Pesticides; Carbon; Atrazine; Cellulose; Water; Dimethoate; Chlorpyrifos; Diuron; Saccharum; Charcoal; Adsorption; Water Pollutants, Chemical; Kinetics
PubMed: 37586496
DOI: 10.1016/j.chemosphere.2023.139819 -
Chemosphere Oct 2023Protozoa are sensitive indicators of pollutant toxicity. This review presents and discusses the toxicological studies of protozoa and the toxicological conventional test... (Review)
Review
Protozoa are sensitive indicators of pollutant toxicity. This review presents and discusses the toxicological studies of protozoa and the toxicological conventional test species (Daphnia magna) by pesticides and nanomaterials, particularly comparing the sensitivity of through relative tolerance analysis, Z-score, and species sensitivity index. The sensitivity of different species of protozoa varies greatly. The protozoa Paramecium sp. and Tetrahymena sp. are not sensitive species; conversely, Urostyla sp. is sensitive to dimethoate and nanomaterials Ag-NPs, respectively ZnO-NPs, and CuO-NPs, fits the use as an indicator species on these substances. The prospects to explore scientific toxicity exposure protocols, expand the protozoan species examined, and screen the sensitive species under the protocols are discussed. This prospect review advances the knowledge for including the sensitive protozoa as an indicator species in comprehensive toxicological analysis for pesticides and nanomaterials.
Topics: Animals; Pesticides; Metal Nanoparticles; Dimethoate; Environmental Pollutants; Nanostructures; Daphnia
PubMed: 37549748
DOI: 10.1016/j.chemosphere.2023.139749 -
Pest Management Science Dec 2023Although the pupal parasitoid Trichopria drosophilae is used in conservative and augmentative biocontrol of Drosophila suzukii infestations, current pest management...
BACKGROUND
Although the pupal parasitoid Trichopria drosophilae is used in conservative and augmentative biocontrol of Drosophila suzukii infestations, current pest management strategies mostly rely on multiple insecticide applications. In this context, the aim of the study was to investigate the baseline toxicity of nine insecticides on D. suzukii larvae and their multiple sublethal effects (LC ) on immature stages of the pest feeding on contaminated diet and T. drosophilae developing within the intoxicated host.
RESULTS
Chlorpyriphos and azadirachtin showed the lowest and the highest LC , the values of which were 9.78 × 10 and 1.46 × 10 times lower than their recommended label field rate, respectively. Among tested insecticides, imidacloprid, malathion and dimethoate were the only treatments that did not affect the juvenile development time of D. suzukii, while spinosad and the organophosphates chlorpyriphos and dimethoate did not influence fly pupal size. No sublethal effects were recorded on T. drosophilae degree of infestation (DI) and juvenile development time. On the contrary, cyazypyr and dimethoate negatively affected the success of parasitism (SP) and the number of progeny of the pupal parasitoid, in association with malathion for the first parameter and spinosad for the fertility. Compared to the untreated control, more female progeny emerged following azadirachtin exposure, while dimethoate caused the opposite effect. Imidacloprid, lambda-cyhalothrin and spinetoram decreased hind tibia length of emerged parasitoids.
CONCLUSION
This study provides new insights on the (eco)toxicological profile of nine insecticides and new information needed to support the deployment of T. drosophilae in the field within the sustainable management techniques against D. suzukii. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Topics: Animals; Female; Insecticides; Drosophila; Dimethoate; Malathion; Pupa; Hymenoptera
PubMed: 37548138
DOI: 10.1002/ps.7702 -
Environmental Pollution (Barking, Essex... Oct 2023The similarity of sensitivity of adult Africanised and European honeybees following acute oral exposure to thiamethoxam has been questioned. Data collated from adult...
The similarity of sensitivity of adult Africanised and European honeybees following acute oral exposure to thiamethoxam has been questioned. Data collated from adult acute contact and oral toxicity testing of a range of thiamethoxam containing products (solo and mixtures) shows that the toxicity of these products to Africanised honeybees can be directly predicted from the toxicity of the active substances to European honeybees. Similarly, the acute contact and oral toxicity of dimethoate to Africanised bees lies within the same range as European honeybees. There are no major differences in the sensitivity of Africanised and European honeybee individuals to thiamethoxam and dimethoate.
Topics: Bees; Animals; Thiamethoxam; Dimethoate; Neonicotinoids; Thiazoles; Toxicity Tests; Insecticides
PubMed: 37479172
DOI: 10.1016/j.envpol.2023.122230 -
Environmental Toxicology and Chemistry Nov 2023Lethal and sublethal effects of pesticides on nontarget organisms are one of the causes of the current decline of many insect species. However, research in the past...
Lethal and sublethal effects of pesticides on nontarget organisms are one of the causes of the current decline of many insect species. However, research in the past decades has focused primarily on pollinators, although other beneficial nontarget organisms such as parasitic wasps may also be affected. We studied the sublethal effects of the four insecticides acetamiprid, dimethoate, flupyradifurone, and sulfoxaflor on pheromone-mediated sexual communication and olfactory host finding of the parasitic wasp Nasonia vitripennis. All agents target cholinergic neurons, which are involved in the processing of chemical information by insects. We applied insecticide doses topically and tested the response of treated wasps to sex pheromones and host-associated chemical cues. In addition, we investigated the mating rate of insecticide-treated wasps. The pheromone response of females surviving insecticide treatment was disrupted by acetamiprid (≥0.63 ng), dimethoate (≥0.105 ng), and flupyradifurone (≥21 ng), whereas sulfoxaflor had no significant effects at the tested doses. Olfactory host finding was affected by all insecticides (acetamiprid ≥1.05 ng, dimethoate ≥0.105 ng, flupyradifurone ≥5.25 ng, sulfoxaflor ≥0.52 ng). Remarkably, females treated with ≥0.21 ng dimethoate even avoided host odor. The mating rate of treated N. vitripennis couples was decreased by acetamiprid (6.3 ng), flupyradifurone (≥2.63 ng), and sulfoxaflor (2.63 ng), whereas dimethoate showed only minor effects. Finally, we determined the amount of artificial nectar consumed by N. vitripennis females within 48 h. Considering this amount (∼2 µL) and the maximum concentrations of the insecticides reported in nectar, tested doses can be considered field-realistic. Our results suggest that exposure of parasitic wasps to field-realistic doses of insecticides targeting the cholinergic system reduces their effectiveness as natural enemies by impairing the olfactory sense. Environ Toxicol Chem 2023;42:2400-2411. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Topics: Animals; Female; Wasps; Insecticides; Dimethoate; Plant Nectar; Sex Attractants; Cholinergic Neurons
PubMed: 37477474
DOI: 10.1002/etc.5721 -
Journal of Hazardous Materials Sep 2023In this study, graphene-like biochar (IZBC) was prepared by pyrolysis of wheat straw in the presence of catalyst and activator. The formation of graphene in IZBC could...
In this study, graphene-like biochar (IZBC) was prepared by pyrolysis of wheat straw in the presence of catalyst and activator. The formation of graphene in IZBC could be divided into three stages: shell core generation, carburization, and carbon precipitation. When the pyrolysis temperatures were in the ranges of 500-600 ℃, 600-700 ℃, 700-800 ℃ and 800-900 ℃, 17%, 32%, 13% and 38% of graphene were produced, respectively. The contribution ratios of graphene by FeCl, ZnCl and HCl were 64%, 23% and 13%, respectively. Moreover, IZBC was filled with porous wavy three-dimensional graphene nanosheets that enabled self-aggregation to be effectively prevented, which was superior to the striped two-dimensional structure. The adsorption of IZBC for dimethoate was a spontaneous exothermic reaction with the adsorption capacity of 980 μmol/g, which was consistent with the pseudo-second-order and intraparticle diffusion models. The adsorption was inhibited by coexisting cations, anions, and humic acid in water. Dimethoate was adsorbed on graphene through embedded separation, with pore filling, cation-π and electrostatic attraction as the key driving forces. In addition, the adsorbed saturated IZBC could be effectively regenerated for many times by 2 mol/L HCl solution.
PubMed: 37354717
DOI: 10.1016/j.jhazmat.2023.131893 -
The Science of the Total Environment Oct 2023With the widespread use of pesticides, the coexistence of multiple low-residue pesticides in environmental media has increased significantly, and the "cocktail" effect...
With the widespread use of pesticides, the coexistence of multiple low-residue pesticides in environmental media has increased significantly, and the "cocktail" effect caused by this phenomenon has garnered increasing attention. However, owing to the scarcity of information regarding the modes of action (MOAs) of chemicals, the application of concentration addition (CA) models for evaluating and predicting the toxicity of mixture with similar MOAs is limited. Additionally, the joint toxicity laws of complex mixture systems to different toxicity endpoints in organisms remain unclear, and effective methods to test the mixture toxicity on lifespan and reproductive inhibition are lacking. Therefore, in this study, the similarity of pesticide MOAs was characterized using molecular electronegativity-distance vector (MEDV-13) descriptors based on eight pesticides (aldicarb, methomyl, imidacloprid, thiamethoxam, dichlorvos, dimethoate, methamidophos and triazophos). Additionally, the methods of lifespan and reproduction inhibition microplate toxicity analysis of elegans (EL-MTA and ER-MTA) were established to test the lifespan and reproduction inhibition toxicity of Caenorhabditis elegans. Finally, a unified scale synergistic-antagonistic heatmap (SAHscale) method was proposed to explore the combined toxicity of the mixtures on the lifespan, reproduction, and mortality of nematodes. The results showed that the MEDV-13 descriptors could effectively characterize the similarity in MOAs. The lifespan and reproductive ability of Caenorhabditis elegans were significantly inhibited when the pesticide exposure concentration was one order of magnitude lower than the lethal dose. The sensitivity of lifespan and reproductive endpoints to mixtures was dependent on the concentration ratio. The same rays in the mixture had consistent toxicity interactions on the lifespan and reproductive endpoints of Caenorhabditis elegans. In conclusion, we demonstrated the feasibility of MEDV-13 in characterizing the similarity of MOAs, and provided a theoretical basis for exploring the mechanism of chemical mixtures by studying their apparent toxicity of mixtures on nematode lifespan and reproduction endpoints.
Topics: Animals; Caenorhabditis elegans; Pesticides; Nematoda; Dose-Response Relationship, Drug; Dimethoate
PubMed: 37327899
DOI: 10.1016/j.scitotenv.2023.164918 -
International Journal of Environmental... Mar 2024The chronic dietary risk assessment for 34 pesticides suspected of acting as endocrine disrupters in Iran was assessed by comparing TMDI with the Acceptable Daily...
The chronic dietary risk assessment for 34 pesticides suspected of acting as endocrine disrupters in Iran was assessed by comparing TMDI with the Acceptable Daily Intakes (ADI). Of 34 investigated endocrine-disrupting pesticides (EDPs), 6 had TMDI > ADI. In addition, potential non-carcinogenic and carcinogenic health risk assessments were evaluated using Monte Carlo simulation. HQ in wheat was 17.40 and 20.29 in adults and children, respectively. Due to dimethoate residue in wheat, HQ was 2.78, and for fenitrothion residue, 3.22. HI was 21.22 for adults and 24.76 for children in wheat, more than 1. Total Carcinogenic risk (TCR) due to EDPs residues was 6.40 × 10 in apples, in citrus fruits 5.97 × 10, 3.33 × 10 in cucumber, 5.30 × 10 in lettuce, in potato was 2.36 × 10, in rice was 1.61 × 10, 1.78 × 10 in tomato, and due to epoxiconazole residues in wheat was 3.18 × 10, more than acceptable limit 1.0 × 10. Therefore, consumers were at significant risk of carcinogenesis. PCBs: polychlorinated biphenyls; BPA: Bisphenol A; ED: Endocrine Disrupting; EDCs: Endocrine Disrupting Chemicals; EDPs: Endocrine Disrupting Pesticides; ADI: Acceptable Daily Intake; TMDI: Theoretical Maximum Daily Intake; FAO: Food and Agriculture Organization; WHO: World Health Organization; MRL: Maximum Residue Limit; HQ: Hazard Quotient; HI: Hazard Index; CR: Cancer Risk; TCR: Total Cancer Risk; PPP: plant protection products.
Topics: Child; Adult; Humans; Pesticides; Iran; Food Contamination; Pesticide Residues; Risk Assessment; Carcinogens; Polychlorinated Biphenyls; Neoplasms; Receptors, Antigen, T-Cell
PubMed: 37017094
DOI: 10.1080/09603123.2023.2199193