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Archives of Environmental &... 2021The mining industry has one of the highest rates of occupational disease across all industries. However, occupational skin disease (OSD) is not commonly reported in this...
The mining industry has one of the highest rates of occupational disease across all industries. However, occupational skin disease (OSD) is not commonly reported in this industry, although has been estimated to affect up to 51 people per 100,000 workers, with contact dermatitis accounting for the majority of cases. It often has a poor prognosis and leads to days lost from work. There have been relatively few reports regarding the specific forms of OSD encountered by miners worldwide. We report our experience of miners attending our Occupational Dermatology Clinic and our investigations at two Australian mines. We compare our findings with other reports of OSD in the mining population. The most commonly observed skin condition was irritant contact dermatitis, but miliaria and allergic contact dermatitis were also observed. It is not surprising that most cases of OSD appear to be related to harsh working conditions and exposures to multiple skin irritants, however, specific exposures causing ACD should not be forgotten. Our findings are consistent with previous studies of OSD in miners.
Topics: Australia; Dermatitis, Occupational; Female; Humans; Male; Mining; Occupational Exposure; Retrospective Studies; Tertiary Care Centers
PubMed: 33372583
DOI: 10.1080/19338244.2020.1857674 -
European Journal of Dermatology : EJD Dec 2020Hypohidrosis can result in heat injury, a potentially fatal condition. The majority of hypohidrosis cases have no associated abnormalities or secondary causes, and are...
BACKGROUND
Hypohidrosis can result in heat injury, a potentially fatal condition. The majority of hypohidrosis cases have no associated abnormalities or secondary causes, and are termed "isolated hypohidrosis". These are clinically divided into miliaria profunda (MP), acquired idiopathic generalized anhidrosis (AIGA) and idiopathic partial hypohidrosis (IPH). The pathogenesis of isolated hypohidrosis remains largely unknown and there is no established effective treatment.
OBJECTIVES
To elucidate the pathogenesis of isolated hypohidrosis using in vivo high-definition optical coherence tomography (HD-OCT) imaging and assess the therapeutic profile of oral retinoids for this condition.
MATERIALS & METHODS
We conducted a retrospective analysis on all patients with isolated hypohidrosis in our neuro-dermatology clinic over a 5.75-year period. All patients routinely underwent standardised exercising and whole-body starch-iodine testing, followed by non-invasive HD-OCT skin imaging. Patients' demographics, disease characteristics, histology and treatment history were analysed.
RESULTS
Of the 51 patients identified with isolated hypohidrosis; 23 were diagnosed with MP, 14 with AIGA, and 14 with IPH. In these patients, HD-OCT imaging led to the identification of sub-stratum corneal hypo-refractile material with underlying dilated sweat ducts, not present in healthy controls. The size of this material was most pronounced in MP, followed by AIGA, and then IPH. Post-treatment, the material decreased in size. Treatment response was reported in 90.6% patients with isotretinoin and 75.0% with acitretin. No recurrence has been reported to date. Side effects were largely anticipated and common.
CONCLUSION
The pathogenesis of isolated hypohidrosis involves obstruction of sweat orifices at the stratum corneum. Treatment with oral retinoids, particularly isotretinoin, is effective and safe.
Topics: Adult; Female; Humans; Hypohidrosis; Male; Retrospective Studies; Tomography, Optical Coherence; Young Adult
PubMed: 33262099
DOI: 10.1684/ejd.2020.3931 -
Dermatologic Therapy Jan 2021Prevalence of dermatological manifestations of coronavirus disease 2019 (COVID-19) is estimated between 0.25% and 3% in children and adolescents. In this review article,... (Review)
Review
Prevalence of dermatological manifestations of coronavirus disease 2019 (COVID-19) is estimated between 0.25% and 3% in children and adolescents. In this review article, we decided to describe the cutaneous and histopathological manifestations of COVID-19 infection in pediatrics. We searched published articles in PubMed database for key words of "children" or "pediatric" and "cutaneous" or "dermatology" or "skin" and "COVID-19" or "SARS-CoV-2" or "Coronavirus disease 2019" in abstract or title from December of 2019 until September 2020. Finally, 38 articles were selected. The majority of patients were between 11 and 17 years old with predominantly male gender. Most of the patients were either asymptomatic or had a few general symptoms. The latency time from appearance of general symptoms to cutaneous ones was between 1 day and weeks. Skin lesions faded between 3 and 88 days without any sequelae, spontaneously or with either topical or systemic corticosteroids. Skin manifestations were chilblain-like (pseudochilblain), erythema multiforme-like, dactylitis, acral erythema, acute urticaria, livedo reticularis, mottling, acro-ischemia, generalized maculopapular lesions, eyelid dermatitis, miliaria-like, varicelliform lesions, and petechiae and/or purpura. Kawa-COVID-19 patients were presented more frequently with cardiogenic shock, neurological symptoms, lymphocytopenia, and thrombocytopenia as compared to classic Kawasaki's disease. Furthermore, more number of cases were resistant to the first-line treatments.
Topics: Adolescent; COVID-19; Child; Humans; Pediatrics; SARS-CoV-2; Skin; Skin Diseases
PubMed: 33210417
DOI: 10.1111/dth.14554 -
Actas Dermo-sifiliograficas Oct 2020
Topics: Child; Fox-Fordyce Disease; Humans
PubMed: 32563546
DOI: 10.1016/j.ad.2019.03.016 -
Journal of Cosmetic and Laser Therapy :... Apr 2020Fox-Fordyce disease (FFD) is an uncommon apocrine disorder. We reported a 26-year-old woman with bilateral axillary pruritic papular lesions following 2 sessions of...
Fox-Fordyce disease (FFD) is an uncommon apocrine disorder. We reported a 26-year-old woman with bilateral axillary pruritic papular lesions following 2 sessions of treatment with Diode (800 nm) laser for axillary hair removal. No lesions were developed in the other treated areas. Topical 0.1% tacrolimus gel was used for her treatment.
Topics: Adult; Axilla; Female; Fox-Fordyce Disease; Hair Removal; Humans; Laser Therapy; Low-Level Light Therapy
PubMed: 32506979
DOI: 10.1080/14764172.2020.1774062 -
Journal of the European Academy of... Aug 2020
Topics: Betacoronavirus; COVID-19; Coronavirus Infections; Face; Female; Humans; Miliaria; Pandemics; Pneumonia, Viral; SARS-CoV-2; Ventilators, Mechanical
PubMed: 32386442
DOI: 10.1111/jdv.16624 -
Archives of Disease in Childhood. Fetal... Sep 2020
Topics: Humans; Infant, Newborn; Male; Miliaria; Photography; Water
PubMed: 32312743
DOI: 10.1136/archdischild-2020-319008 -
Dermatologic Therapy Mar 2020Fox-Fordyce disease (FFD) is a rare pruritic dermatosis whose etiology has not been fully explored. It is mostly seen in women and presents as pruritic follicular...
Fox-Fordyce disease (FFD) is a rare pruritic dermatosis whose etiology has not been fully explored. It is mostly seen in women and presents as pruritic follicular papules at the apocrine (gland-bearing) regions, including the axilla, groins, perineum, and areola mammae, as well as the umbilicus. Treatment for FFD is extremely challenging in that there is no curative treatment for it. We report the case of a 26-year-old woman who was refractory to many treatments but who responded to calcipotriol betamethasone with rapid remission of her symptoms.
Topics: Adult; Axilla; Betamethasone; Calcitriol; Female; Fox-Fordyce Disease; Hair Removal; Humans
PubMed: 31917488
DOI: 10.1111/dth.13223 -
The Journal of Dermatology Mar 2020
Topics: Adrenal Gland Neoplasms; Child, Preschool; Female; Hidradenitis; Humans; Hyperhidrosis; Miliaria; Neuroblastoma; Skin
PubMed: 31912533
DOI: 10.1111/1346-8138.15224 -
Indian Dermatology Online Journal 2019Sweat dermatitis is a peculiar kind of irritant inflammatory dermatoses occurring due to prolonged exposure of retained sweat over the skin. It is commonly seen in hot...
Sweat dermatitis is a peculiar kind of irritant inflammatory dermatoses occurring due to prolonged exposure of retained sweat over the skin. It is commonly seen in hot and dry climates like tropics during summer months due to thermal stress. Typically, parchment paper or cellophane paper like scaling is seen over occluded areas of back, shoulder, and other areas. Here we have reported a varied presentation of sweat dermatitis in the form of its coexistence with miliaria rubra (impending to thermal burn). Further we have also observed co existing pityriasis versicolor and sweat dermatitis where the former has prevented the development of latter. Till date there is very little discussion on this condition, so we have tried to provide a concise review about sweat dermatitis along with its classical to atypical presentation with special emphasis on dermoscopy.
PubMed: 31807452
DOI: 10.4103/idoj.IDOJ_5_19