-
CEN Case Reports Nov 2014Bacterial peritonitis remains a life-threatening complication of peritoneal dialysis (PD). Roseomonas is a bacterial genus of pink-pigmented, oxidized, gram-negative...
Bacterial peritonitis remains a life-threatening complication of peritoneal dialysis (PD). Roseomonas is a bacterial genus of pink-pigmented, oxidized, gram-negative coccobacilli that was first named in 1993. Importantly, Roseomonas mucosa exhibits antibiotic resistance, with significant resistance to cephalosporin, which is often selected as an empirical antibiotic regimen for peritonitis in PD patients. We herein report the case of a PD patient with bacterial peritonitis caused by Roseomonas mucosa that was fortunately identified using 16S rRNA gene sequencing and successfully treated with ciprofloxacin. Given that Roseomonas demonstrates resistance to a variety of antibiotics. The administration of empiric antibiotic therapy based on the recommendation of the International Society of Peritoneal Dialysis guidelines occasionally fails, leading to the aggravation of bacterial peritonitis. Hence, nephrologists should consider Roseomonas as one of the potential causative organisms of peritonitis, especially when gram-negative bacilli are resistant to cephalosporin and cannot be identified using standard laboratory methods.
PubMed: 28509185
DOI: 10.1007/s13730-013-0101-2 -
Transplant Infectious Disease : An... Aug 2013Roseomonas are pink-pigmented, oxidative, slowly growing, nonfermentative, gram-negative coccobacilli whose identification may require extensive biochemical testing and...
Roseomonas are pink-pigmented, oxidative, slowly growing, nonfermentative, gram-negative coccobacilli whose identification may require extensive biochemical testing and molecular profiling. Roseomonas infections vary in severity and clinical presentation, and they predominantly occur in immunocompromised and chronically ill patients. The organism is generally susceptible to carbapenems and aminoglycosides, but resistant to most of the cephalosporins and broad-spectrum penicillins. Reported here is a patient with lymphoblastic lymphoma who developed Roseomonas mucosa bacteremia after receiving her hematopoietic stem cell allograft. The bacteremic episode was successfully treated with imipenem and amikacin in addition to removal of the central venous catheter. To our knowledge, this is the first report of Roseomonas bacteremia in a stem cell transplantation recipient.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Female; Gram-Negative Bacterial Infections; Hematopoietic Stem Cell Transplantation; Humans; Methylobacteriaceae; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous
PubMed: 23725464
DOI: 10.1111/tid.12100 -
Bacteremia due to imipenem-resistant Roseomonas mucosa in a child with acute lymphoblastic leukemia.Journal of Pediatric Hematology/oncology Apr 2014Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial...
Roseomonas are described as opportunistic pathogens rarely involved in human infections. Their identification requires molecular methods and their antimicrobial susceptibility pattern varies according to the species. We report the first case of bacteremia due to Roseomonas mucosa in a child with leukemia and reviewed pediatric cases of Roseomonas infection, for which undoubted strain identification was available. Favorable outcome was observed despite resistance to numerous β-lactams that may account for delayed effective treatment, suggesting the low virulence of Roseomonas in children. Here, the strain also displayed unusual resistance to imipenem, highlighting the possible acquisition of additional resistance by this pathogen.
Topics: Anti-Bacterial Agents; Bacteremia; Child; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Imipenem; Methylobacteriaceae; Mucous Membrane; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prognosis
PubMed: 23669726
DOI: 10.1097/MPH.0b013e318290d503 -
Journal of Clinical Microbiology Jul 2013The first case of a spinal epidural abscess caused by Roseomonas mucosa following instrumented posterior lumbar fusion is presented. Although rare, because of its highly...
The first case of a spinal epidural abscess caused by Roseomonas mucosa following instrumented posterior lumbar fusion is presented. Although rare, because of its highly resistant profile, Roseomonas species should be included in the differential diagnosis of epidural abscesses in both immunocompromised and immunocompetent hosts.
Topics: DNA, Bacterial; Epidural Abscess; Female; Gram-Negative Bacterial Infections; Humans; Methylobacteriaceae; Middle Aged; Molecular Sequence Data; Sequence Analysis, DNA; Surgical Wound Infection
PubMed: 23596239
DOI: 10.1128/JCM.00512-13 -
Journal of Clinical Microbiology Nov 2012We report the first case of peritonitis caused by Roseomonas mucosa which led to technique failure in an adolescent patient with HIV receiving peritoneal dialysis....
We report the first case of peritonitis caused by Roseomonas mucosa which led to technique failure in an adolescent patient with HIV receiving peritoneal dialysis. Identification of the causative organism by 16S rRNA gene sequencing and phylogenetic analysis is described.
Topics: Adolescent; Bacterial Typing Techniques; Cluster Analysis; Cross Infection; DNA, Bacterial; DNA, Ribosomal; Gram-Negative Bacterial Infections; HIV Infections; Humans; Methylobacteriaceae; Peritoneal Dialysis; Peritonitis; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Young Adult
PubMed: 22933600
DOI: 10.1128/JCM.01437-12 -
Journal of Clinical Microbiology Aug 2010We report a case of catheter-related bacteremia associated with Roseomonas mucosa isolated from an immunocompromised pediatric patient with a history of multiple...
We report a case of catheter-related bacteremia associated with Roseomonas mucosa isolated from an immunocompromised pediatric patient with a history of multiple episodes of urinary tract infection and bacteremia.
Topics: Adolescent; Bacteremia; Bacteriological Techniques; Catheter-Related Infections; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Male; Methylobacteriaceae
PubMed: 20534804
DOI: 10.1128/JCM.02349-09 -
International Journal of Systematic and... May 2009Phylogenetic analyses based on 16S rRNA gene sequences revealed that Teichococcus ludipueritiae and Muricoccus roseus are closely related to the species of the genus...
Transfer of Teichococcus ludipueritiae and Muricoccus roseus to the genus Roseomonas, as Roseomonas ludipueritiae comb. nov. and Roseomonas rosea comb. nov., respectively, and emended description of the genus Roseomonas.
Phylogenetic analyses based on 16S rRNA gene sequences revealed that Teichococcus ludipueritiae and Muricoccus roseus are closely related to the species of the genus Roseomonas. The type strain of Teichococcus ludipueritiae, 170/96(T), exhibited 16S rRNA gene sequence similarity levels of 96.4 % to Roseomonas cervicalis ATCC 49957(T), 95.0 % to Roseomonas aquatica TR53(T), 94.5 % to Muricoccus roseus 173/96(T), 93.4 % to Roseomonas mucosa ATCC BAA-692(T) and 93.5 % to Roseomonas gilardii subsp. gilardii ATCC 49956(T), while Muricoccus roseus 173/96(T) showed 16S rRNA gene sequence similarity values of 95.7 % to R. mucosa ATCC BAA-692(T), 95.7 % to R. aquatica TR53(T) and 95.3 % to R. gilardii subsp. gilardii ATCC 49956(T) and R. gilardii subsp. rosea ATCC BAA-691(T). Different phylogenetic analysis methods (neighbour-joining, maximum-likelihood and maximum-parsimony) confirmed that both species are within the Roseomonas branch. Neither polyamine patterns (spermidine predominant) nor major characteristics in the polar lipid profiles distinguished the two species from representatives of the genus Roseomonas. The fatty acid composition of the two species exhibited alphaproteobacterial characteristics but, like Roseomonas species, they also showed considerable amounts of the rarely encountered C(18 : 1) 2-OH. On the other hand, they showed some phenotypic differences, but their features are compatible with the transfer of these two species to the genus Roseomonas. We propose the reclassification of Teichococcus ludipueritiae and Muricoccus roseus as Roseomonas ludipueritiae comb. nov. (type strain 170/96(T) =CIP 107418(T) =DSM 14915(T)) and Roseomonas rosea comb. nov. (type strain 173/96(T) =CIP 107419(T) =DSM 14916(T)), respectively. Emended descriptions of the genus Roseomonas and the species Roseomonas gilardii (and its subspecies Roseomonas gilardii subsp. gilardii and Roseomonas gilardii subsp. rosea), Roseomonas aquatica, Roseomonas cervicalis, Roseomonas mucosa and Roseomonas lacus are provided.
Topics: Bacterial Typing Techniques; DNA, Bacterial; Fatty Acids; Genes, rRNA; Methylobacteriaceae; Phenotype; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Species Specificity
PubMed: 19406818
DOI: 10.1099/ijs.0.004820-0 -
Microbiology and Immunology 2007Strain K-20, a Gram-negative, non-motile, non-spore-forming and strictly aerobic rod, which produces a pale pink pigment, was isolated from biofilm in a cooling tower in...
Strain K-20, a Gram-negative, non-motile, non-spore-forming and strictly aerobic rod, which produces a pale pink pigment, was isolated from biofilm in a cooling tower in Tokyo, Japan. The taxonomic feature of the strain was studied using phenotypic tests and phylogenetic analysis. Phylogenetic analysis of 16S rRNA gene sequences showed that the strain was related to Roseomonas gilardii subsp. rosea, Roseomonas gilardii subsp. gilardii, Roseomonas cervicalis and Roseomonas mucosa at 94.3-94.6 sequence similarities. Growth occurred at 25-40 C and pH 5.0-10.0, optimal at 35 C and pH 7.0. Growth did not occur in the presence of >or=2% NaCl. The API 20NE identification system gave a positive result for urease, L-arabinose, potassium gluconate, adipic acid, malic acid and trisodium citrate (API code number 0201465). The predominant fatty acids of strain K-20 were C18:1Delta11 (50.8%) and C16:1 (17.2%). Cells contained ubiquinone 10 (Q-10) as the major quinone and the G+C content was 72.0 mol%. Based on phenotypic, chemotaxonomic and phylogenetic data, it was assumed that strain K-20 (=JCM 14634) is a novel species of the genus Roseomonas.
Topics: Base Composition; Base Sequence; Biofilms; DNA, Bacterial; Fatty Acids; Methylobacteriaceae; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Pigmentation; Polymerase Chain Reaction; RNA, Ribosomal, 16S; Sequence Alignment; Tokyo; Water Microbiology
PubMed: 17579276
DOI: 10.1111/j.1348-0421.2007.tb03951.x -
Journal of Medical Microbiology Aug 2006A case of central venous catheter-related bacteraemia due to Roseomonas mucosa in a neutropenic patient with acute myelogenous leukaemia is reported. The patient was...
A case of central venous catheter-related bacteraemia due to Roseomonas mucosa in a neutropenic patient with acute myelogenous leukaemia is reported. The patient was successfully treated with amikacin and piperacillin-tazobactam. The clinical isolate was identified as R. mucosa by 16S rRNA gene sequencing.
Topics: Acute Disease; Adult; Amikacin; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bacteremia; Base Sequence; Catheterization, Central Venous; Cytarabine; Humans; Leukemia, Myeloid; Male; Methylobacteriaceae; Molecular Sequence Data; Neutropenia; Penicillanic Acid; Phylogeny; Piperacillin; Piperacillin, Tazobactam Drug Combination; RNA, Bacterial; RNA, Ribosomal, 16S; Vidarabine
PubMed: 16849738
DOI: 10.1099/jmm.0.46634-0 -
Diagnostic Microbiology and Infectious... Aug 2006We report a case of septic arthritis due to Roseomonas mucosa in a rheumatoid arthritis patient receiving infliximab therapy. This is the first report of septic...
We report a case of septic arthritis due to Roseomonas mucosa in a rheumatoid arthritis patient receiving infliximab therapy. This is the first report of septic arthritis due to R. mucosa, and infliximab therapy might be a predisposing factor because this infection was never reported in the pre-anti-tumor necrosis factor alpha therapy period.
Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Infectious; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Infliximab; Male; Methylobacteriaceae; Molecular Sequence Data
PubMed: 16626905
DOI: 10.1016/j.diagmicrobio.2006.01.028