-
Acta Dermato-venereologica Oct 2020
Topics: Acanthoma; Ankle; Dermoscopy; Erythema; Humans; Skin Neoplasms
PubMed: 32985678
DOI: 10.2340/00015555-3651 -
Dermatology Practical & Conceptual Oct 2023
Non-invasive Imaging Techniques for the Diagnosis of Clear Cell Acanthomas: Dermoscopy, Reflectance Confocal Microscopy and Line-Field Confocal Optical Coherence Tomography.
PubMed: 37992357
DOI: 10.5826/dpc.1304a231 -
Anais Brasileiros de Dermatologia 2020
Topics: Acanthoma; Biopsy; Dermoscopy; Female; Humans; Middle Aged; Skin Neoplasms; Thorax
PubMed: 32265053
DOI: 10.1016/j.abd.2019.06.015 -
Annals of Dermatology Jun 2021Clear cell acanthoma (CCA) is an uncommon, benign epithelial tumor presenting as a well-defined, slow-growing solitary nodule. The diagnosis of CCA is usually based on...
Clear cell acanthoma (CCA) is an uncommon, benign epithelial tumor presenting as a well-defined, slow-growing solitary nodule. The diagnosis of CCA is usually based on clinical and histopathological evaluation of the tumor. However, when such type of benign tumor occurs on an exposed area, a biopsy is not always the best diagnostic option since it may leave scar. The recent advent of dermoscopy has offered an accurate and non-invasive method to diagnose CCA without resorting to skin biopsy. A 40-year-old male presented with a shiny, erythematous-to-brown, flattened nodule on the left cheek. Dermoscopic examination revealed a 'string of pearls' vascular pattern, a characteristic dermoscopic feature of CCA. Under the clinical and dermoscopic impression of CCA, a 595 nm pulsed dye laser (PDL) therapy targeting the vascular tissue in the superficial dermis of the lesion was chosen for a minimally invasive treatment. After repeated sessions of PDL, an optimal cosmetic outcome was achieved and no recurrence was recorded during the follow-up period. Herein, we report a case of presumed CCA which was successfully diagnosed and treated by utilizing non-invasive modalities.
PubMed: 34079188
DOI: 10.5021/ad.2021.33.3.275 -
Acta Dermato-venereologica 2009We describe two patients with multiple epidermolytic acanthomas on the scrotum initially referred to our clinic as genital warts. Both patients presented with multiple...
We describe two patients with multiple epidermolytic acanthomas on the scrotum initially referred to our clinic as genital warts. Both patients presented with multiple tan-colored warty papules scattered on the scrotal skin. Biopsy revealed hyperkeratosis, hypergranulosis, and clear cell changes consistent with epidermolytic acanthoma. Human papillomavirus was not detected and the lesions cleared rapidly with a liquid nitrogen cryoprobe. Despite only a few reports of multiple epidermolytic acanthomas of the scrotum, it may not be as rare as previously thought. In addition, genital localization of the wart-like lesions may lead to confusion with other conditions such as condylomata acuminata, molluscum contagiosum, or bowenoid papulosis.
Topics: Acanthoma; Adult; Diagnosis, Differential; Genital Diseases, Male; Humans; Male; Middle Aged; Papillomavirus Infections; Scrotum; Skin Neoplasms; Warts
PubMed: 19326003
DOI: 10.2340/00015555-0607 -
JAAD Case Reports Aug 2018
PubMed: 30128341
DOI: 10.1016/j.jdcr.2018.04.009 -
Journal of Oral Science Sep 2009Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes. Although its pathogenenesis remains...
Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes. Although its pathogenenesis remains uncertain, its clinical behavior and spontaneous remission suggest a non-neoplastic nature. Clinically, it may present as a solitary or multifocal lesion; however these two variants exhibit different features. The clinical appearance of OMA is not pathognomonic and biopsy is mandatory. OMA requires no treatment or periodic observation. Here, we report a case of OMA with diffuse lesions also affecting the tongue in a 74-year-old black woman, whose diagnosis was based essentially on clinical and histological features. The immunohistochemical profile is also presented.
Topics: Acanthoma; Aged; Female; Humans; Melanocytes; Melanosis; Mouth Mucosa; Mouth Neoplasms; Neoplasm Regression, Spontaneous
PubMed: 19776516
DOI: 10.2334/josnusd.51.463 -
Anais Brasileiros de Dermatologia 2014
Topics: Acanthoma; Female; Humans; Nipples; Skin Neoplasms
PubMed: 24626678
DOI: 10.1590/abd1806-4841.20143184 -
Annals of Dermatology Aug 2010Clear cell acanthoma (CCA) is a rare benign epidermal tumor. It usually presents as a flat nodule or dome-shaped plaque and is often localized on the legs of the...
Clear cell acanthoma (CCA) is a rare benign epidermal tumor. It usually presents as a flat nodule or dome-shaped plaque and is often localized on the legs of the elderly. We observed an unusual case of polypoid CCA on the nipple of a 14-year-old girl. At present, a few cases of CCA on the nipple area have been reported in the literature. However, CCA presented as a polypoid tumor on the nipple area has been reported very rarely. We herein report the very rare case of polypoid CCA on the nipple and suggest that CCA should be included in the clinical differential diagnosis of polypoid lesions on the nipple.
PubMed: 20711275
DOI: 10.5021/ad.2010.22.3.337 -
F1000Research 2020Oral melanoacanthoma is not common. It occurs mostly on the buccal mucosa. Since it happens suddenly and progresses rapidly, it clinically resembles melanoma....
Oral melanoacanthoma is not common. It occurs mostly on the buccal mucosa. Since it happens suddenly and progresses rapidly, it clinically resembles melanoma. Melanoacanthoma occurs in regions susceptible to trauma. The clinical presentation of the lesion is not enough to diagnose it; therefore, tissue biopsy is necessary to exclude malignancy. We report a case of oral melanoacanthoma in a rare mucosal location in a 21-year old female patient in whom generalized gingival melanoacanthoma was related to the use of the teeth whitening strips. This irritating factor increased melanocyte activity in the gingival tissues and labial mucosa. Oral melanoacanthoma is a rarely encountered pigmented lesion in the oral cavity and is especially uncommon in the gingiva. It is a reactive lesion affecting the mucous membranes with no risk of malignant transformation. This case report shows that teeth whitening strips may trigger oral melanoacanthoma in susceptible individuals. Long-term irritation of the oral tissues may increase the number of dendritic melanocytes throughout the epithelium and accordingly increase the brown pigmentation of the oral cavity. Eliminating all possible local sources of irritation and ruling out other causative factors are the standard first step in the treatment of oral melanoacanthoma. This case shows the importance of including oral melanoacanthoma in the differential diagnosis of diffuse gingival pigmented lesions.
Topics: Acanthoma; Adult; Female; Gingiva; Humans; Mouth Neoplasms; Skin Neoplasms; Tooth Bleaching; Young Adult
PubMed: 33447386
DOI: 10.12688/f1000research.27999.2