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Longitudinal Development of Distortion Product Otoacoustic Emissions in Infants With Normal Hearing.Ear and Hearing 2018The purpose of this study was to describe normal characteristics of distortion product otoacoustic emission (DPOAE) signal and noise level in a group of newborns and...
OBJECTIVES
The purpose of this study was to describe normal characteristics of distortion product otoacoustic emission (DPOAE) signal and noise level in a group of newborns and infants with normal hearing followed longitudinally from birth to 15 months of age.
DESIGN
This is a prospective, longitudinal study of 231 infants who passed newborn hearing screening and were verified to have normal hearing. Infants were enrolled from a well-baby nursery and two neonatal intensive care units (NICUs) in Cincinnati, OH. Normal hearing was confirmed with threshold auditory brainstem response and visual reinforcement audiometry. DPOAEs were measured in up to four study visits over the first year after birth. Stimulus frequencies f1 and f2 were used with f2/f1 = 1.22, and the DPOAE was recorded at frequency 2f1-f2. A longitudinal repeated-measure linear mixed model design was used to study changes in DPOAE level and noise level as related to age, middle ear transfer, race, and NICU history.
RESULTS
Significant changes in the DPOAE and noise levels occurred from birth to 12 months of age. DPOAE levels were the highest at 1 month of age. The largest decrease in DPOAE level occurred between 1 and 5 months of age in the mid to high frequencies (2 to 8 kHz) with minimal changes occurring between 6, 9, and 12 months of age. The decrease in DPOAE level was significantly related to a decrease in wideband absorbance at the same f2 frequencies. DPOAE noise level increased only slightly with age over the first year with the highest noise levels in the 12-month-old age range. Minor, nonsystematic effects for NICU history, race, and gestational age at birth were found, thus these results were generalizable to commonly seen clinical populations.
CONCLUSIONS
DPOAE levels were related to wideband middle ear absorbance changes in this large sample of infants confirmed to have normal hearing at auditory brainstem response and visual reinforcement audiometry testing. This normative database can be used to evaluate clinical results from birth to 1 year of age. The distributions of DPOAE level and signal to noise ratio data reported herein across frequency and age in normal-hearing infants who were healthy or had NICU histories may be helpful to detect the presence of hearing loss in infants.
Topics: Audiometry; Cochlea; Ear, Middle; Female; Hearing; Hearing Tests; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Noise; Otoacoustic Emissions, Spontaneous; Reference Values
PubMed: 29369290
DOI: 10.1097/AUD.0000000000000542 -
Otology & Neurotology : Official... Apr 2022Describe early hearing preservation (HP) cochlear implantation (CI) outcomes using a new slim lateral wall electrode (SLWE).
OBJECTIVE
Describe early hearing preservation (HP) cochlear implantation (CI) outcomes using a new slim lateral wall electrode (SLWE).
STUDY DESIGN
Prospective cohort study.
SETTING
Tertiary referral center.
PATIENTS
Adult CI candidates with preoperative low-frequency pure-tone average (LFPTA; 125, 250, 500 Hz) ≤60 dB HL.
INTERVENTION
CI with and without intracochlear real-time electrocochleography (RT-ECochG).
MAIN OUTCOME MEASURE
HP (LFPTA ≤80 dB HL), LFPTA shift, speech-perception performance measures, postoperative CT reconstruction.
RESULTS
Forty-two subjects were implanted with the SLWE. Thirty patients underwent full insertion without RT-ECochG feedback, and HP was maintained at 3-months postactivation for 7 (23.3%) patients with mean LFPTA shift of 57.5 ± 25.6 dB HL. RT-ECochG feedback was utilized on 12 patients, of whom 6 patients had full insertions and 6 patients had anywhere from 1 to 3 electrodes left outside of the cochlea based on RT-ECochG feedback. At 3 months postoperatively, HP was achieved on 10 (83.3%) patients and mean LFPTA shift was 18.9 c 11.7 dB HL. Mean difference between LFPTA threshold shift at 3-months postactivation with and without RT-ECochG was 38.6 dB HL (95% CI, 25.6-51.67). There was an improvement in delta CNC from preoperative to 3-months postactivation when using RT-ECochG, with mean difference 20.7% (95% CI, 3.3-38.1).
CONCLUSIONS
Use of RT-ECochG monitoring during SLWE placement results in fewer full electrode insertions and significantly better HP rates and speech-perception outcomes when compared with unmonitored insertions. Further investigation is needed to evaluate long-term audiologic outcomes to better understand the relationships among ECochG, cochlear trauma, functional outcomes, and HP.
Topics: Adult; Audiometry, Evoked Response; Audiometry, Pure-Tone; Auditory Threshold; Cochlear Implantation; Cochlear Implants; Hearing; Humans; Prospective Studies; Treatment Outcome
PubMed: 35170555
DOI: 10.1097/MAO.0000000000003475 -
Nihon Ronen Igakkai Zasshi. Japanese... Sep 1990Presbyacusis is senescence in the auditory system. Currently, the etiology of presbyacusis is thought to be mainly due to environmental noise and arterial sclerosis.... (Review)
Review
Presbyacusis is senescence in the auditory system. Currently, the etiology of presbyacusis is thought to be mainly due to environmental noise and arterial sclerosis. Cumulative effects of social noise influence the auditory function gradually. Sclerotic change of arteries in the brain occurs along the total auditory pathway. Histopathological findings reveal characteristic changes in all parts of the auditory pathway in elderly persons. Alterations include thickening of the ear drum, sclerotic change of the ossicles joint, decreasing number of hair cells, degeneration of the eighth nerve and of the neurons in the auditory center. Pure tone audiograms show gradually progressive sensorineural hearing loss at high frequencies due to lesions characteristic of senescence. During the 30's the threshold at 8 KHz increases a little, but in the 60's the pure tone threshold increases over all frequencies. The maximum speech discrimination parallels the drop in the pure tone threshold level. In contrast to the normal speech discrimination score, the speech discrimination score using frequency distorted words is very low in senile persons. There is no known therapy for presbyacusis. Hearing aids compensate hearing impairment to some extent, but patient's adaptation to hearing aids is undetermined.
Topics: Aged; Aged, 80 and over; Audiometry, Pure-Tone; Hearing Aids; Humans; Presbycusis; Speech Discrimination Tests
PubMed: 2263009
DOI: 10.3143/geriatrics.27.545 -
British Medical Journal Nov 1967
Clinical Trial
Topics: Audiometry; Auditory Threshold; Auscultation; Humans
PubMed: 6054915
DOI: 10.1136/bmj.4.5576.388 -
Lin Chuang Er Bi Yan Hou Tou Jing Wai... Jan 2022Chronic otitis media is a common condition in otology, which mainly manifests as repeated purulence, hearing loss, eardrum perforation and other discomforts. It often... (Review)
Review
Chronic otitis media is a common condition in otology, which mainly manifests as repeated purulence, hearing loss, eardrum perforation and other discomforts. It often causes adverse impacts on the health and quality of life of patients. In the past, the assessment of symptoms and prognosis of chronic otitis media was limited to objective examinations such as audiometry or ear endoscopy, while patients' subjective feelings about the disease were ignored. This study reviewed the content, characteristics and current clinical application of quality of life scales for chronic otitis media, with the aim of providing a basis for the selection of quality of life scales for chronic otitis media.
Topics: Audiometry; Chronic Disease; Humans; Otitis Media; Quality of Life; Tympanic Membrane Perforation
PubMed: 34979626
DOI: 10.13201/j.issn.2096-7993.2022.01.017 -
Ear and Hearing 2018The first objective of this study was to compare the predicted audiometric thresholds obtained by auditory steady state response (ASSR) and auditory brainstem response... (Comparative Study)
Comparative Study
Evaluation of Speed and Accuracy of Next-Generation Auditory Steady State Response and Auditory Brainstem Response Audiometry in Children With Normal Hearing and Hearing Loss.
OBJECTIVES
The first objective of this study was to compare the predicted audiometric thresholds obtained by auditory steady state response (ASSR) and auditory brainstem response (ABR) in infants and toddlers when both techniques use optimal stimuli and detection algorithms. This information will aid in determining the basis for large discrepancies in ABR and ASSR measures found in past studies. The hypothesis was that advancements in ASSR response detection would improve (lower) thresholds and decrease discrepancies between the thresholds produced by the two techniques. The second objective was to determine and compare test times required by the two techniques to predict thresholds for both ears at the 4 basic audiometric frequencies of 500, 1000, 2000, and 4000 Hz.
DESIGN
A multicenter clinical study was implemented at three university-based children's hospital audiology departments. Participants were 102 infants and toddlers referred to the centers for electrophysiologic testing for audiometric purposes. The test battery included wideband tympanometry, distortion-product otoacoustic emissions, and threshold measurements at four frequencies in both ears using ABR and ASSR (randomized) as implemented on the Interacoustics Eclipse systems with "Next-Generation" ASSR detection and FMP analysis for ABR. Both methods utilized narrow band CE-Chirp stimuli. Testers were trained on a specialized test battery designed to minimize test time for both techniques. Testing with both techniques was performed in one session. Thresholds were evaluated and confirmed by the first author and correction factors were applied. Test times were documented in system software.
RESULTS
Corrected thresholds for ABR and ASSR were compared by regression, by the Bland-Altman technique and by matched pairs t tests. Thresholds were significantly lower for ASSR than ABR. The ABR-ASSR discrepancy at 500 Hz was 14.39 dB, at 1000 Hz was 10.12 dB, at 2000 Hz was 3.73 dB, and at 4000 Hz was 3.67 dB. The average test time for ASSR of 19.93 min (for 8 thresholds) was found to be significantly lower (p < 0.001) than the ABR test time of 32.15 min. One half of the subjects were found to have normal hearing. ASSR thresholds plotted in dB nHL for normal-hearing children in this study were found to be the lowest yet described except for one study which used the same technology.
CONCLUSIONS
This study found a reversal of previous findings with up to 14 dB lower thresholds found when using the ASSR technique with "Next-Generation" detection as compared with ABR using an automated detection (FMP). The test time for an audiogram prediction was significantly lower when using ASSR than ABR but was excellent by clinical standards for both techniques. ASSRs improved threshold performance was attributed to advancements in response detection including utilization of information at multiple harmonics of the modulation frequency. The stimulation paradigm which utilized narrow band CE-Chirps also contributed to the low absolute levels of the thresholds in nHL found with both techniques.
Topics: Audiometry; Audiometry, Evoked Response; Auditory Threshold; Child; Child, Preschool; Evoked Potentials, Auditory, Brain Stem; Female; Hearing; Hearing Loss; Humans; Infant; Male
PubMed: 29624540
DOI: 10.1097/AUD.0000000000000580 -
Journal of the Formosan Medical... Jul 2014To establish a real-time, web-based, customized audiometry database system, we worked in cooperation with the departments of medical records, information technology, and...
To establish a real-time, web-based, customized audiometry database system, we worked in cooperation with the departments of medical records, information technology, and otorhinolaryngology at our hospital. This system includes an audiometry data entry system, retrieval and display system, patient information incorporation system, audiometry data transmission program, and audiometry data integration. Compared with commercial audiometry systems and traditional hand-drawn audiometry data, this web-based system saves time and money and is convenient for statistics research.
Topics: Audiometry; Database Management Systems; Databases, Factual; Electronic Health Records; Female; Humans; Internet; Male; Middle Aged
PubMed: 24262921
DOI: 10.1016/j.jfma.2013.10.006 -
British Medical Journal Sep 1978
Topics: Audiometry; Hearing Loss, Noise-Induced; Humans; Occupational Diseases
PubMed: 698687
DOI: 10.1136/bmj.2.6138.706 -
PLoS Biology Oct 2004A fresh look at classic work of Thomas Gold on how the inner ear processes sound (Review)
Review
A fresh look at classic work of Thomas Gold on how the inner ear processes sound
Topics: Acoustic Stimulation; Acoustics; Animals; Audiometry; Audiometry, Pure-Tone; Auditory Perception; Auditory Threshold; Cochlea; Cochlear Microphonic Potentials; Hearing; Humans; Vibration
PubMed: 15486577
DOI: 10.1371/journal.pbio.0020337 -
Clinics (Sao Paulo, Brazil) Apr 2015To compare the efficacy and feasibility of teleaudiometry with that of sweep audiometry in elementary school children, using pure-tone audiometry as the gold standard. (Comparative Study)
Comparative Study
OBJECTIVE
To compare the efficacy and feasibility of teleaudiometry with that of sweep audiometry in elementary school children, using pure-tone audiometry as the gold standard.
METHODS
A total of 243 students with a mean age of 8.3 years participated in the study. Of these, 118 were boys, and 125 were girls. The following procedures were performed: teleaudiometry screening with software that evaluates hearing at frequencies of 1,000, 2000 and 4000 Hz at 25 dBHL; sweep audiometry screening in an acoustic booth (20 dBHL at the same frequencies); pure-tone audiometry thresholds in an acoustic booth (frequencies of 500, 1000, 2000 and 4000 Hz); and acoustic immittance measurements.
RESULTS
The diagnostic capacities of the teleaudiometry/sweep audiometry screening methods were as follows: sensitivity ϝ 58%/65%; specificity ϝ 86%/99%; positive predictive value ϝ 51%/91%; negative predictive value ϝ 89%/92%; and accuracy ϝ 81%/92%. Teleaudiometry and sweep audiometry showed moderate agreement. Furthermore, the use of these methods in series with immittance testing improved the specificity, whereas parallel testing improved the sensitivity.
CONCLUSION
Teleaudiometry was found to be reliable and feasible for screening hearing in school children. Moreover, teleaudiometry is the preferred method for remote areas where specialized personnel and specific equipment are not available, and its use may reduce the costs of hearing screening programs.
Topics: Adolescent; Audiometry; Audiometry, Pure-Tone; Auditory Threshold; Child; Feasibility Studies; Female; Hearing Loss; Humans; Male; Mass Screening; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Software; Telemedicine
PubMed: 26017796
DOI: 10.6061/clinics/2015(04)11