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The Annals of Otology, Rhinology, and... Aug 1995The acquired immunodeficiency syndrome and other causes of immunosuppression have ushered in a variety of opportunistic infections. One of these is bacillary... (Review)
Review
The acquired immunodeficiency syndrome and other causes of immunosuppression have ushered in a variety of opportunistic infections. One of these is bacillary angiomatosis, a vasoproliferative lesion whose principal causative agent is Rochalimaea henselae. Bacillary angiomatosis, while preponderantly a cutaneous affliction, can be systemic, including involvement of the head and neck mucous membranes. Molecular technology and epidemiologic studies used to identify the bacterial agent of bacillary angiomatosis have also uncovered R henselae as the organism responsible for most cases of cat-scratch disease. Why the same organism promotes two different histopathologic lesions, as seen in bacillary angiomatosis and cat-scratch disease, is unknown.
Topics: Angiomatosis, Bacillary; Bartonella henselae; Cat-Scratch Disease; Diagnosis, Differential; Granuloma, Pyogenic; Humans; Risk Factors; Sarcoma, Kaposi
PubMed: 7543738
DOI: 10.1177/000348949510400815 -
AIDS Clinical ReviewThe manifestations of bacillary angiomatosis include diverse cutaneous lesions, visceral parenchymal bacillary peliosis of the spleen and liver, and involvement of... (Review)
Review
The manifestations of bacillary angiomatosis include diverse cutaneous lesions, visceral parenchymal bacillary peliosis of the spleen and liver, and involvement of single or multiple organ systems. The organisms causing BA are R. henselae and R. quintana, and these organisms have now been cultured from the spleen and cutaneous lesions of BA as well as the blood of patients with visceral and cutaneous BA. The antibiotic regimen of choice for HIV-infected patients is erythromycin 500 mg 4 x a day for 2-4 months, but relapse may necessitate lifelong suppressive therapy. We are maintaining a registry of patients with bacillary angiomatosis and request that we be contacted (415-206-8680, UCSF) if you diagnose a case, preferably before therapy is instituted.
Topics: AIDS-Related Opportunistic Infections; Angiomatosis, Bacillary; Erythromycin; Humans
PubMed: 8217903
DOI: No ID Found -
International Journal of Dermatology Jan 1992
Review
Topics: Angiomatosis, Bacillary; Humans
PubMed: 1737682
DOI: 10.1111/j.1365-4362.1992.tb03512.x -
Clinics in Dermatology 1996
Review
Topics: AIDS-Related Opportunistic Infections; Angiomatosis, Bacillary; Bartonella; Cat-Scratch Disease; Diagnosis, Differential; Humans
PubMed: 8727133
DOI: 10.1016/0738-081x(96)00015-6 -
The American Journal of Tropical... Sep 2014
Topics: AIDS-Related Opportunistic Infections; Adult; Angiomatosis, Bacillary; Anti-Bacterial Agents; Bartonella; Biopsy; CD4 Lymphocyte Count; DNA, Ribosomal Spacer; Diagnosis, Differential; Doxycycline; Face; Humans; Male; Skin; Treatment Outcome
PubMed: 25187668
DOI: 10.4269/ajtmh.13-0561 -
Revista Da Sociedade Brasileira de... 2022
Topics: AIDS-Related Opportunistic Infections; Angiomatosis, Bacillary; Humans
PubMed: 35976332
DOI: 10.1590/0037-8682-0101-2022 -
Modern Pathology : An Official Journal... Feb 1995
Topics: AIDS-Related Opportunistic Infections; Angiomatosis, Bacillary; Bartonella; Capillaries; Diagnosis, Differential; Humans; Skin
PubMed: 7539912
DOI: No ID Found -
Cureus Mar 2023Bacillary angiomatosis (BA) is an angioproliferative disease caused by species. It manifests as nodules or papules in immunocompromised patients. Oral lesions are very...
Bacillary angiomatosis (BA) is an angioproliferative disease caused by species. It manifests as nodules or papules in immunocompromised patients. Oral lesions are very rare, unlike cutaneous lesions, and histopathology plays a vital role in distinguishing these lesions from other similar ones. Treatment mainly comprises macrolides erythromycin, clarithromycin, or doxycycline.
PubMed: 37123686
DOI: 10.7759/cureus.36844 -
IDCases 2019We report a case of bacillary angiomatosis in a solid organ transplant recipient with typical skin lesions. Bacillary angiomatosis is an uncommon disease characterized...
We report a case of bacillary angiomatosis in a solid organ transplant recipient with typical skin lesions. Bacillary angiomatosis is an uncommon disease characterized by neovascular proliferation caused by infection with Bartonella henselae or Bartonella quintana. Bacillary angiomatosis was first described in patients with HIV and CD4 cell counts <100/μL, but also occur in patients with other causes of immune deficiency. The disease usually manifests as skin tumors, and may involve other organs, most commonly the spleen and liver, known as peliosis. The involvement of internal organs can lead to fatal disease. Diagnosis is based on histology, culture, PCR and serology. The optimal antibiotic regimen and treatment duration for bacillary angiomatosis has not been established. Most authors recommend prolonged treatment (usually 12 weeks) of doxycycline or macrolide with addition of rifampicin or gentamycin for patients with severe disease. Recurrence after treatment is not rare. Suppressive therapy may be considered for patients with relapse after 12 weeks of therapy and continuous immunosuppression.
PubMed: 31828013
DOI: 10.1016/j.idcr.2019.e00649 -
Journal Der Deutschen Dermatologischen... Sep 2009An infection with Bartonella henselae transmitted from domestic cats to humans by scratching normally leads to cat-scratch disease. When the human host has severe...
An infection with Bartonella henselae transmitted from domestic cats to humans by scratching normally leads to cat-scratch disease. When the human host has severe immunosuppression or HIV infection, the potentially life-threatening disease bacillary angiomatosis can develop. A 79-year-old man presented with livid-erythematous, angioma-like skin lesions. We considered a cutaneous infiltrate from his known chronic lymphocytic leukemia, Merkel cell carcinoma, cutaneous metastases of internal tumors, cutaneous sarcoidosis, mycobacterial infection and even atypical herpes simplex infection. The correct diagnosis was proven histologically and by PCR. Because of increasing numbers of immunosuppressed and HIV-positive patients, as well as an infection rate of 13% for B. henselae in domestic cats in Germany, one must be alert to the presence of bacillary angiomatosis.
Topics: Aged; Angiomatosis, Bacillary; Bartonella henselae; Cat-Scratch Disease; Diagnosis, Differential; Herpes Simplex; Humans; Male; Skin Neoplasms
PubMed: 19298547
DOI: 10.1111/j.1610-0387.2009.07055.x