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Journal of Bacteriology Dec 2020
Topics: Bacteriology; History, 20th Century; History, 21st Century; Periodicals as Topic
PubMed: 33077629
DOI: 10.1128/JB.00549-20 -
Clinical Microbiology and Infection :... May 2011
Topics: Automation, Laboratory; Bacteriology; Clinical Laboratory Techniques; Humans
PubMed: 21521407
DOI: 10.1111/j.1469-0691.2011.03511.x -
Current Biology : CB Mar 2021Interview with Erin Goley, who studies the mechanisms governing bacterial morphogenesis and the regulation of bacterial growth in changing environments at Johns Hopkins...
Interview with Erin Goley, who studies the mechanisms governing bacterial morphogenesis and the regulation of bacterial growth in changing environments at Johns Hopkins University School of Medicine.
Topics: Bacteria; Bacteriology; Environment; History, 21st Century; Humans; Mentoring; Social Media
PubMed: 33689713
DOI: 10.1016/j.cub.2021.01.023 -
Journal of Bacteriology Jun 2022
Topics: Bacteriology; Microbiology
PubMed: 35583338
DOI: 10.1128/jb.00153-22 -
Nihon Saikingaku Zasshi. Japanese... 2018
Topics: Animals; Bacteria; Bacterial Infections; Bacteriology; Fungi; Genome, Bacterial; Humans; Microbiology; Societies, Scientific
PubMed: 29479024
DOI: 10.3412/jsb.73.50 -
Pneumologie (Stuttgart, Germany) Jan 2017
Review
Topics: Bacteriology; Germany; History, 19th Century; History, 20th Century; Humans; Physicians, Women; Pulmonary Medicine; Tuberculosis; United States
PubMed: 28114707
DOI: 10.1055/s-0042-118031 -
Nihon Saikingaku Zasshi. Japanese... 2017
Topics: Animals; Bacteriology; Humans
PubMed: 28239049
DOI: 10.3412/jsb.72.71 -
Frontiers in Immunology 2023The discovery of gasdermin D (GSDMD) as the terminal executioner of pyroptosis provided a large piece of the cell death puzzle, whilst simultaneously and firmly putting... (Review)
Review
The discovery of gasdermin D (GSDMD) as the terminal executioner of pyroptosis provided a large piece of the cell death puzzle, whilst simultaneously and firmly putting the gasdermin family into the limelight. In its purest form, GSDMD provides a connection between the innate alarm systems to an explosive, inflammatory form of cell death to jolt the local environment into immunological action. However, the gasdermin field has moved rapidly and significantly since the original seminal work and novel functions and mechanisms have been recently uncovered, particularly in response to infection. Gasdermins regulate and are regulated by mechanisms such as autophagy, metabolism and NETosis in fighting pathogen and protecting host. Importantly, activators and interactors of the other gasdermins, not just GSDMD, have been recently elucidated and have opened new avenues for gasdermin-based discovery. Key to this is the development of potent and specific tool molecules, so far a challenge for the field. Here we will cover some of these recently discovered areas in relation to bacterial infection before providing an overview of the pharmacological landscape and the challenges associated with targeting gasdermins.
Topics: Gasdermins; Bacteriology; Intracellular Signaling Peptides and Proteins; Pyroptosis; Cell Death
PubMed: 37266429
DOI: 10.3389/fimmu.2023.1173519 -
Pneumologie (Stuttgart, Germany) May 2015
Topics: Bacteriology; Germany; History, 19th Century; Internal Medicine; Tuberculosis
PubMed: 25970124
DOI: 10.1055/s-0034-1391843 -
Journal of Bacteriology Jan 2018
Topics: Bacteriology; Humans; Peer Review, Research; Periodicals as Topic; Societies, Scientific
PubMed: 29084861
DOI: 10.1128/JB.00635-17