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Lakartidningen Aug 1975
Review
Topics: Benzopyrenes; Coal Tar; Environmental Exposure; Humans; Neoplasms; Occupational Diseases
PubMed: 1100943
DOI: No ID Found -
Medicina Clinica Jan 2002
Topics: Benzopyrenes; Humans; Plant Oils
PubMed: 11803007
DOI: 10.1016/s0025-7753(02)72270-7 -
The Journal of Organic Chemistry Dec 2022Reaction of 6-nitrochrysene with ethyl isocyanoacetate in the presence of a non-nucleophilic base gave a -annulated pyrrole ethyl ester that was used to prepare...
Reaction of 6-nitrochrysene with ethyl isocyanoacetate in the presence of a non-nucleophilic base gave a -annulated pyrrole ethyl ester that was used to prepare chrysene-fused tripyrranes and a chrysopyrrole dialdehyde. Chrysene-fused tripyrranes were reacted with a pyrrole dialdehyde, but poor yields of chrysoporphyrins were obtained. However, condensation of the chrysopyrrole dialdehyde with a series of tripyrranes afforded excellent yields of chrysoporphyrins and an acenaphtho-chrysoporphyrin. Iron(III) chloride mediated oxidative cyclization of a dihexylchrysoporphyrin afforded a benzopyrene-fused porphyrin that exhibited a strongly red-shifted electronic absorption spectrum. DFT calculations show that both chrysoporphyrins and the benzopyrene-fused porphyrin have tautomers that possess 34π electron delocalization pathways that pass through the porphyrin nucleus and the fused polycyclic aromatic hydrocarbon (PAH) units. Protonation gave dications that favor 36-atom 34π electron circuits. -Annulated pyrrole dialdehydes were also condensed with a carbatripyrrin to generate PAH-fused carbaporphyrins that retained fully aromatic properties.
Topics: Chrysenes; Ferric Compounds; Porphyrins; Benzopyrenes; Benzo(a)pyrene
PubMed: 36459435
DOI: 10.1021/acs.joc.2c01859 -
Chemosphere Mar 2024Benzopyrene (BaP) stands as a potent polycyclic aromatic hydrocarbon (PAH) molecule, boasting five fused aromatic rings, making its way into the human food chain through...
Benzopyrene (BaP) stands as a potent polycyclic aromatic hydrocarbon (PAH) molecule, boasting five fused aromatic rings, making its way into the human food chain through soil contamination. The persistent environmental presence of PAHs in soil, attributed to industrial exposure, is primarily due to their low molecular weight and hydrophobic nature. To preemptively address the entry of BaP into the food chain, the application of nanocomposites was identified as an effective remediation strategy. Post-synthesis, comprehensive characterization tests employing techniques such as UV-DRS, XRD, SEM-EDX, FTIR, and DLS unveiled the distinctive features of the g-CN-SnS nanocomposites. These nanocomposites exhibited spherical shapes embedded on layers of nanosheets, boasting particle diameters measuring 88.9 nm. Subsequent tests were conducted to assess the efficacy of eliminating benzopyrene from a combination of PAH molecules and g-CN-SnS nanocomposites. Varied parameters, including PAH concentration, adsorbent dosage, and suspension pH, were systematically explored. The optimized conditions for the efficient removal of BaP utilizing the g-CN-SnS nanocomposite involved 2 μg/mL of benzopyrene, 10 μg/mL of the nanocomposite, and a pH of 5, considering UV light as the irradiation source. The investigation into the mechanism governing BaP elimination closely aligned with batch adsorption results involved a thorough exploration of adsorption kinetics and isotherms. Photocatalytic degradation of benzopyrene was achieved, reaching a maximum of 86 % in 4 h and 36 % in 2 h, with g-CN-SnS nanocomposite acting as the catalyst. Further validation through HPLC data confirmed the successful removal of BaP from the soil matrix.
Topics: Humans; Nanocomposites; Graphite; Benzo(a)pyrene; Benzopyrenes; Polycyclic Aromatic Hydrocarbons; Soil; Catalysis; Nitrogen Compounds
PubMed: 38307332
DOI: 10.1016/j.chemosphere.2024.141352 -
Food and Cosmetics Toxicology Aug 1972
Review
Topics: Animals; Benzopyrenes; Bile; Carbon Isotopes; Fish Products; Food Analysis; Humans; Japan; Meat; Mixed Function Oxygenases; Rats; United States; Vegetables
PubMed: 4563249
DOI: No ID Found -
Food and Cosmetics Toxicology Aug 1965
Topics: Benzopyrenes
PubMed: 5859247
DOI: 10.1016/s0015-6264(65)80098-0 -
Methods in Enzymology 1984
Topics: Animals; Benzopyrenes; Bile; Carcinogens; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Oxidation-Reduction; Oxygen Consumption; Rats; Spectrophotometry; Structure-Activity Relationship
PubMed: 6328205
DOI: 10.1016/s0076-6879(84)05074-6 -
Food Chemistry Oct 2020This study was aimed to reduce the concentrations of benzopyrene (BaP) and acrylamide (ACR) in roasted coffee beans by corona discharge plasma jet (CDPJ). The initial...
This study was aimed to reduce the concentrations of benzopyrene (BaP) and acrylamide (ACR) in roasted coffee beans by corona discharge plasma jet (CDPJ). The initial concentrations of BaP and ACR in roasted beans were decreased by 53.6% and 32.0%, respectively, following CDPJ (powered by 20 kV DC/1.5 A) treatment for 60 min. The levels of total solid, total acid, chlorogenic acid, caffeine, trigonelline, and pH were insignificantly changed upon CDPJ treatment compared to controls. However, the concentration of total phenolic content and Agtron color values were altered significantly. The treatment of beans did not alter descriptive sensory properties of the corresponding coffee brews, except aroma and aftertaste characteristics. As the treatment time increased from 15 to 60 min, scores for aroma profiles in PCA plot were shifted from right to left, although overlapping was observed between 15- and 30-min-treated samples. Additionally, none of the treated samples were discriminated from the control by electronic tongue.
Topics: Acrylamide; Alkaloids; Benzopyrenes; Biochemical Phenomena; Caffeine; Chlorogenic Acid; Coffee; Cooking; Electronic Nose; Hot Temperature
PubMed: 32474240
DOI: 10.1016/j.foodchem.2020.127117 -
International Journal of Environmental... Oct 2022In this study, we investigated whether the levels of sulfur dioxide (SO), benzopyrene, and mycotoxins in herbal decoctions in Korea in 2019 were within normal limits. In...
In this study, we investigated whether the levels of sulfur dioxide (SO), benzopyrene, and mycotoxins in herbal decoctions in Korea in 2019 were within normal limits. In total, 30 decoctions composed of multi-ingredient traditional herbs were sampled from traditional Korean medicine (TKM) clinics, TKM hospitals, and external herbal dispensaries in 2019. The decoctions were analyzed for SO, benzopyrene, and mycotoxins using 10 samples. SO and benzopyrene were not detected in any of the herbal decoctions. With regard to mycotoxins, aflatoxin B1 was not detected, but B2 was detected in 7 cases (0.00~0.04 ppb), G1 in 13 cases (0.03~0.29 ppb), and G2 in 9 cases (0.02~0.93 ppb). None of these values exceeded the restrictions in prior studies. Thus, we confirm that the amounts of SO, benzopyrene, and mycotoxins in herbal decoctions are at safe levels and provides the basis of establishing safety management criteria for herbal decoctions.
Topics: Mycotoxins; Sulfur Dioxide; Medicine, Traditional; Benzopyrenes; Benzo(a)pyrene; Aflatoxins
PubMed: 36294180
DOI: 10.3390/ijerph192013595 -
Biochemical Society Transactions Aug 1992
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Biological Transport; Cell Division; Cell Line; Humans; Kinetics; Mice; Microsomes
PubMed: 1426564
DOI: 10.1042/bst020279s