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Journal of Clinical Microbiology Mar 2023
Review
Topics: Humans; Aged; Flavobacteriaceae; Bacteremia; Gram-Negative Bacterial Infections
PubMed: 36951461
DOI: 10.1128/jcm.00408-22 -
Closing the Brief Case: Bergeyella zoohelcum Bacteremia in an Immunocompromised 69-Year-Old Patient.Journal of Clinical Microbiology Mar 2023
Review
Topics: Humans; Aged; Flavobacteriaceae; Bacteremia; Gram-Negative Bacterial Infections
PubMed: 36951459
DOI: 10.1128/jcm.00409-22 -
Zoonoses and Public Health Dec 2019Bergeyella zoohelcum causes rare but severe human clinical diseases, which mostly arise from animal bites. Notably, Bergeyella infections can also occur in older people...
Bergeyella zoohelcum causes rare but severe human clinical diseases, which mostly arise from animal bites. Notably, Bergeyella infections can also occur in older people after prolonged exposure to dogs or cats without biting. We detected B. zoohelcum in oral cavities of therapy dogs in close contact with older people residing in nursing homes. Twenty-two bacterial isolates were identified as B. zoohelcum by using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing. Our results showed that MALDI-TOF MS is an effective tool for rapid identification of rarely isolated, difficult-to-identify microorganisms, such as B. zoohelcum, derived from not only human clinical samples but also animal samples. To our knowledge, this is the first report on detection of B. zoohelcum from therapy dogs. We have provided information on dog-assisted therapy to improve the relationship between humans and animals in ageing societies, particularly for preventive healthcare of older people living in nursing care facilities.
Topics: Animals; Dog Diseases; Dogs; Flavobacteriaceae; Flavobacteriaceae Infections; Homes for the Aged; Humans; Japan; Mouth; RNA, Ribosomal, 16S; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
PubMed: 31464049
DOI: 10.1111/zph.12644 -
Systematic and Applied Microbiology May 2016Four Gram-stain-negative, catalase- and oxidase-positive, bacillus-shaped bacterial isolates were recovered from the lungs and tonsils of four pigs. Based on cellular...
Four Gram-stain-negative, catalase- and oxidase-positive, bacillus-shaped bacterial isolates were recovered from the lungs and tonsils of four pigs. Based on cellular morphology and biochemical criteria the isolates were tentatively assigned to the genus Bergeyella, although the organisms did not appear to correspond with Bergeyella zoohelcum, the only validly named species of this genus. 16S rRNA gene sequencing demonstrated that isolates represented a distinct subline within the genus Bergeyella with <97%. 16S rRNA gene sequence similarity with B. zoohelcum ATCC 43767(T). The predominant cellular fatty acids of strain 1350-03(T) were iso-C15:0 and iso-C17:0 3-OH and the major quinone was MK-6. The DNA G+C content of strain 1350-03(T) was 37.7mol%. The novel isolates can be phenotypically distinguished from B. zoohelcum based on physiological traits. On the basis of both phenotypic and phylogenetic findings, we describe a new species of the genus Bergeyella for which we propose the name of Bergeyella porcorum sp. nov. (1350-03(T)=CCUG 67887(T)=CECT 9006(T)).
Topics: Animals; Bacterial Typing Techniques; Base Composition; DNA, Bacterial; Fatty Acids; Flavobacteriaceae; Lung; Palatine Tonsil; Phenotype; RNA, Ribosomal, 16S; Swine
PubMed: 27039167
DOI: 10.1016/j.syapm.2016.03.006 -
Cureus Apr 2019Bergeyella (B.) zoohelcum is a non-motile, aerobic, gram-negative rod, with only a few cases in the literature. Most of the human infections are related to dog or cat...
Bergeyella (B.) zoohelcum is a non-motile, aerobic, gram-negative rod, with only a few cases in the literature. Most of the human infections are related to dog or cat bites; however, there are also reports related to the ingestion of food prepared with goat's blood. We present a case of Bergeyella zoohelcum bacteremia in a patient with acquired immunodeficiency syndrome (AIDS) following close contact with their service dog. To the best of our knowledge, this is the first case of B. zoohelcum bacteremia in an AIDS patient.
PubMed: 31259112
DOI: 10.7759/cureus.4494 -
Veterinary Journal (London, England :... Apr 2018The aim of this study was to characterise bacteria in the genus Bergeyella isolated from the nasal passages of healthy piglets. Nasal swabs from 3 to 4 week-old piglets...
The aim of this study was to characterise bacteria in the genus Bergeyella isolated from the nasal passages of healthy piglets. Nasal swabs from 3 to 4 week-old piglets from eight commercial domestic pig farms and one wild boar farm were cultured under aerobic conditions. Twenty-nine Bergeyella spp. isolates were identified by partial 16S rRNA gene sequencing and 11 genotypes were discriminated by enterobacterial repetitive intergenic consensus (ERIC)-PCR. Bergeyella zoohelcum and Bergeyella porcorum were identified within the 11 genotypes. Bergeyella spp. isolates exhibited resistance to serum complement and phagocytosis, poor capacity to form biofilms and were able to adhere to epithelial cells. Maneval staining was consistent with the presence of a capsule. Multiple drug resistance (resistance to three or more classes of antimicrobial agents) was present in 9/11 genotypes, including one genotype isolated from wild boar with no history of antimicrobial use. In conclusion, Bergeyella spp. isolates from the nasal cavities of piglets showed some in vitro features indicative of a potential for virulence. Further studies are necessary to identify the role of Bergeyella spp. in disease and within the nasal microbiota of pigs.
Topics: Animals; Anti-Bacterial Agents; Bacterial Typing Techniques; Flavobacteriaceae; Genotype; Microbiota; Nasal Cavity; RNA, Ribosomal, 16S; Swine
PubMed: 29680378
DOI: 10.1016/j.tvjl.2018.01.004 -
BMC Infectious Diseases Apr 2017Bergeyella zoohelcum is an aerobic, Gram-negative bacterium that is frequently isolated from the upper respiratory tract of dogs, cats and other mammals. Clinically, B.... (Review)
Review
BACKGROUND
Bergeyella zoohelcum is an aerobic, Gram-negative bacterium that is frequently isolated from the upper respiratory tract of dogs, cats and other mammals. Clinically, B. zoohelcum has been reported causing cellulitis, tenosynovitis, leg abscess and septicemia, which is closely connected with animal bites. Here we describe a case of bacteremia in an infective endocarditis (IE) patient caused by B. zoohelcum, in China.
CASE PRESENTATION
A 27-year-old infective endocarditis woman who had no history of dog bite nor other mammal exposure suffered bacteremia caused by B. zoohelcum. This patient, without evidence of polymicrobial infection, was treated with cefuroxime and had a good outcome.
CONCLUSIONS
B. zoolhelcum bacteremia is rarely reported in IE patients. Our report expands the range of known bacterial causes of infective endocarditis.
Topics: Adult; Animals; Bacteremia; Bites and Stings; Cats; Cellulitis; China; Dogs; Endocarditis, Bacterial; Female; Gram-Negative Bacteria; Humans; Male; Middle Aged
PubMed: 28403835
DOI: 10.1186/s12879-017-2391-z -
Open Forum Infectious Diseases Apr 2019is a new species in the family Flavobacteriaceae that was recently described in 3 cases of native valve infective endocarditis. We report the first case of prosthetic...
is a new species in the family Flavobacteriaceae that was recently described in 3 cases of native valve infective endocarditis. We report the first case of prosthetic valve endocarditis, provide the first draft genome of this species, and review the microbiologic characteristics of this emerging pathogen.
PubMed: 31024974
DOI: 10.1093/ofid/ofz134 -
Journal of the Formosan Medical... Jul 2007Bergeyella zoohelcum is a rod-shaped, aerobic, Gram-negative, non-motile and non-saccharolytic bacterium. It is frequently isolated from the upper respiratory tract of... (Review)
Review
Bergeyella zoohelcum is a rod-shaped, aerobic, Gram-negative, non-motile and non-saccharolytic bacterium. It is frequently isolated from the upper respiratory tract of dogs, cats and other mammals. Clinically, B. zoohelcum has been known to cause cellulitis, leg abscess, tenosynovitis, septicemia, pneumonia and meningitis, and is associated with animal bites. In addition, food-borne transmission was considered in a recent case report. We report a 73-year-old man with liver cirrhosis who had no history of dog bite but had dog exposure, who developed cellulitis of the left lower leg and B. zoohelcum was isolated from blood culture. This patient, without evidence of polymicrobial infection, was treated with cefazolin and gentamicin with a good outcome. B. zoohelcum is a zoonotic pathogen that may cause bacteremia in patients with underlying disease such as liver cirrhosis; it can be treated with a beta-lactam or quinolone.
Topics: Aged; Animals; Bacteremia; Cellulitis; Dogs; Gram-Negative Aerobic Rods and Cocci; Humans; Male; Zoonoses
PubMed: 17660147
DOI: 10.1016/S0929-6646(07)60008-4 -
Case Reports in Ophthalmological... 2023We report a case of bacterial keratitis secondary to an undescribed sp. spp. are not easily cultured, and many reports have identified unculturable isolates through...
We report a case of bacterial keratitis secondary to an undescribed sp. spp. are not easily cultured, and many reports have identified unculturable isolates through broad-range bacterial polymerase chain reaction (PCR). . A healthy 29-year-old male was attempting to repair an acrylic cannabis water pipe when it shattered and a fragment hit him in the left eye. Two weeks later, he presented with foreign body sensation, scleral injection, and photophobia that were refractory to prolonged corticosteroid therapy. Following a subconjunctival triamcinolone injection, the patient developed a hypopyon and multifocal, midstromal, epithelized corneal infiltrates. Broad-range PCR of the aqueous fluid detected deoxyribonucleic acid closely matching the genus. Empiric treatment directed toward gram-negative bacteria led to the clinical resolution of the inflammation. This is the first reported case of ocular inflammation secondary to a spp.. As broad-range PCR testing becomes more accessible, we anticipate that additional PCR-positive and culture-negative scenarios will occur.
PubMed: 37273837
DOI: 10.1155/2023/3288984