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Jornal Brasileiro de Pneumologia :... 2017Tracheobronchopathia osteochondroplastica is a rare benign disease, of unknown cause, characterized by numerous sessile, cartilaginous, or bony submucosal nodules...
Tracheobronchopathia osteochondroplastica is a rare benign disease, of unknown cause, characterized by numerous sessile, cartilaginous, or bony submucosal nodules distributed throughout the anterolateral walls, projecting into the laryngotracheobronchial lumen. In general, tracheobronchopathia osteochondroplastica is diagnosed incidentally during bronchoscopy or autopsy and is not associated with a specific disease. We report the case of a male patient who was diagnosed with tracheobronchopathia osteochondroplastica via bronchoscopy and biopsy. RESUMO A traqueobroncopatia osteocondroplástica é uma doença benigna rara, de causa desconhecida, caracterizada por numerosos nódulos submucosos sésseis, cartilaginosos e/ou ósseos, distribuídos pelas paredes anterolaterais da traqueia, projetando-se no lúmen laringotraqueobrônquico. Em geral, a traqueobroncopatia osteocondroplástica é descoberta acidentalmente durante broncoscopias ou em necropsias e não é associada a uma doença específica. Relatamos o caso de um paciente que foi diagnosticado com traqueobroncopatia osteocondroplástica por broncoscopia e biópsia.
Topics: Biopsy; Bronchial Diseases; Bronchoscopy; Dyspnea; Humans; Incidental Findings; Male; Middle Aged; Osteochondrodysplasias; Tomography, X-Ray Computed; Tracheal Diseases
PubMed: 28538784
DOI: 10.1590/S1806-37562016000000143 -
Seminars in Respiratory and Critical... Jun 2015Occupational and environmental causes of bronchiolar disorders are recognized on the basis of case reports, case series, and, less commonly, epidemiologic... (Review)
Review
Occupational and environmental causes of bronchiolar disorders are recognized on the basis of case reports, case series, and, less commonly, epidemiologic investigations. Pathology may be limited to the bronchioles or also involve other components of the respiratory tract, including the alveoli. A range of clinical, functional, and radiographic findings, including symptomatic disease lacking abnormalities on noninvasive testing, poses a diagnostic challenge and highlights the value of surgical biopsy. Disease clusters in workplaces and communities have identified new etiologies, drawn attention to indolent disease that may otherwise have been categorized as idiopathic, and expanded the spectrum of histopathologic responses to an exposure. More sensitive noninvasive diagnostic tools, evidence-based therapies, and ongoing epidemiologic investigation of at-risk populations are needed to identify, treat, and prevent exposure-related bronchiolar disorders.
Topics: Animals; Bronchial Diseases; Bronchioles; Environmental Exposure; Humans; Occupational Diseases; Occupational Exposure
PubMed: 26024345
DOI: 10.1055/s-0035-1549452 -
Internal Medicine (Tokyo, Japan) Apr 2023
Topics: Humans; Bronchi; Bronchoscopy; Bronchial Diseases; Trachea
PubMed: 35945016
DOI: 10.2169/internalmedicine.0308-22 -
Internal Medicine (Tokyo, Japan) 2013Diffuse alveolar haemorrhage (DAH) is a serious complication of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). A literature review was... (Review)
Review
Diffuse alveolar haemorrhage (DAH) is a serious complication of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). A literature review was performed to ascertain the diagnostic features, treatment, and outcome of this rare but serious condition. Haemoptysis and dyspnoea are common but non-specific features. Chest radiography is usually abnormal, and high-resolution computerised tomographic scanning is more sensitive. Increased uptake of inhaled carbon monoxide and reduced clearance of C(15)O on lung function testing is suggestive of intra-alveolar blood. Fiberoptic bronchoscopy and bronchoalveolar lavage are useful when a super-added infection is suspected. Concurrent renal disease is common and contributes to the morbidity and mortality. Treatment should be individualised, and it is based on glucocorticoid and cyclophosphamide induction with azathioprine maintenance. The role of plasmapheresis is unclear, and is currently being evaluated. Patients are at risk of disease and treatment-related long-term complications. Ongoing research into the most efficacious therapeutic regimens associated with the least side effects is especially important.
Topics: Adrenal Cortex Hormones; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Bronchial Diseases; Cause of Death; Combined Modality Therapy; Disease Progression; Female; Hemoptysis; Hemorrhage; Humans; Male; Plasmapheresis; Prognosis; Pulmonary Alveoli; Recurrence; Risk Assessment; Severity of Illness Index; Survival Rate
PubMed: 23291668
DOI: 10.2169/internalmedicine.52.8863 -
Canadian Respiratory Journal 2014
Topics: Adult; Amyloidosis; Bronchial Diseases; Humans; Male; Radiography; Trachea; Tracheal Diseases
PubMed: 24524114
DOI: 10.1155/2014/624615 -
Chest Dec 2017Inhaled corticosteroids (ICSs) have become the mainstay of asthma control. They are also recommended as an add-on therapy to long-acting beta agonists and... (Review)
Review
Inhaled corticosteroids (ICSs) have become the mainstay of asthma control. They are also recommended as an add-on therapy to long-acting beta agonists and anticholinergics in moderate to severe COPD with recurrent exacerbations. Ultimately this clinical practice has led to the widespread use of ICSs, which are supported by a more favorable side effect profile than that of systemic steroids.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Asthma; Bronchial Diseases; Humans; Tracheal Diseases
PubMed: 28864055
DOI: 10.1016/j.chest.2017.08.013 -
Thorax Dec 1975Bronchorrohea has been defined as a condition in which more than 100 ml of sputum is produced within 24 hours, an amount in excess of that seen in chronic lung diseases....
Bronchorrohea has been defined as a condition in which more than 100 ml of sputum is produced within 24 hours, an amount in excess of that seen in chronic lung diseases. The rheological and chemical characteristics of the sputum are here described. Levels of viscosity, dry weight, N-acetyl neuraminic acid (NANA), fucose, and sulphate fall between those in saliva and mucoid sputum from chronic lung diseases. These levels were always higher in bronchorrhoea sputum than in saliva and therefore may be used in the differential diagnosis of bronchorrhoea and hypersalivation. Bronchorrhoea sputum has the constituents of a bronchial secretion but is low in acid glycoprotein. Certain other features are commonly found - a large amount of froth, increase in viscosity with time, and separation into two phases. Some cases respond to steroids, particularly when the levels of NANA in the sputum are low.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Bronchial Diseases; Bronchiectasis; Bronchitis; Circadian Rhythm; Elasticity; Female; Fucose; Humans; Lung Neoplasms; Male; Middle Aged; Neuraminic Acids; Sputum; Sulfates; Viscosity
PubMed: 176747
DOI: 10.1136/thx.30.6.624 -
American Family Physician Oct 2011Initial evaluation of the patient with chronic cough (i.e., of more than eight weeks' duration) should include a focused history and physical examination, and in most... (Review)
Review
Initial evaluation of the patient with chronic cough (i.e., of more than eight weeks' duration) should include a focused history and physical examination, and in most patients, chest radiography. Patients who are taking an angiotensin-converting enzyme inhibitor should switch to a medication from another drug class. The most common causes of chronic cough in adults are upper airway cough syndrome, asthma, and gastroesophageal reflux disease, alone or in combination. If upper airway cough syndrome is suspected, a trial of a decongestant and a first-generation antihistamine is warranted. The diagnosis of asthma should be confirmed based on clinical response to empiric therapy with inhaled bronchodilators or corticosteroids. Empiric treatment for gastroesophageal reflux disease should be initiated in lieu of testing for patients with chronic cough and reflux symptoms. Patients should avoid exposure to cough-evoking irritants, such as cigarette smoke. Further testing, such as high-resolution computed tomography, and referral to a pulmonologist may be indicated if the cause of chronic cough is not identified. In children, a cough lasting longer than four weeks is considered chronic. The most common causes in children are respiratory tract infections, asthma, and gastroesophageal reflux disease. Evaluation of children with chronic cough should include chest radiography and spirometry.
Topics: Adult; Asthma; Bronchial Diseases; Child; Chronic Disease; Cough; Diagnosis, Differential; Gastroesophageal Reflux; Humans; Medical History Taking; Physical Examination
PubMed: 22010767
DOI: No ID Found -
Archives of Disease in Childhood Sep 1980
Review
Topics: Bronchial Diseases; Humans; Infant, Newborn; Infant, Premature, Diseases; Intermittent Positive-Pressure Ventilation; Lung Diseases; Prognosis
PubMed: 7002062
DOI: 10.1136/adc.55.9.661 -
Thorax Jun 1999
Topics: Asthma; Bronchial Diseases; Cough; Diagnosis, Differential; Eosinophilia; Histamine; Humans; Predictive Value of Tests; Prospective Studies
PubMed: 10866572
DOI: 10.1136/thx.54.6.562a