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Dermatologic Surgery : Official... Jan 2021VYC-20L is a hyaluronic acid soft tissue filler with lidocaine designed to restore facial volume. (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
VYC-20L is a hyaluronic acid soft tissue filler with lidocaine designed to restore facial volume.
OBJECTIVE
Evaluate the safety and effectiveness of VYC-20L in patients with chin retrusion.
MATERIALS AND METHODS
Adults with chin retrusion were randomized (3:1) to receive VYC-20L in the chin at study onset (treatment group) or 6 months later (control group). The primary effectiveness end point was ≥1-point improvement on the Allergan Chin Retrusion Scale (ACRS) from baseline at Month 6. Safety assessments included injection site responses (ISRs) and adverse events (AEs).
RESULTS
VYC-20L was administered to 192 participants (treatment group, n = 144; control group, n = 48). At Month 6, significantly more participants had an ACRS response in the treatment versus control group (56.3% vs 27.5%; p = .0019). Effectiveness was also demonstrated by the proportion of participants with improved/much improved Global Aesthetic Improvement Scale scores and responses on the FACE-Q Satisfaction with Chin questionnaire and FACE-Q Psychological Wellbeing module. Treatment benefit remained evident at Month 12. Most common ISRs were tenderness (81.1%) and firmness (75.1%). One participant (0.5%) discontinued the study due to 2 treatment-related serious AEs of facial cellulitis and injection site inflammation, both resolved without sequelae.
CONCLUSION
VYC-20L significantly improved an ACRS response and was generally safe and well tolerated.
Topics: Adult; Aged; Aged, 80 and over; Cellulitis; Chin; Cosmetic Techniques; Dermal Fillers; Esthetics; Female; Gels; Humans; Hyaluronic Acid; Injection Site Reaction; Male; Middle Aged; United States
PubMed: 33347003
DOI: 10.1097/DSS.0000000000002795 -
Plastic and Reconstructive Surgery Dec 2022The chin is important for facial appearance, affecting overall balance and harmony of the face. The purpose of this study was to evaluate effectiveness of the hyaluronic... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
The chin is important for facial appearance, affecting overall balance and harmony of the face. The purpose of this study was to evaluate effectiveness of the hyaluronic acid filler Restylane Defyne for chin augmentation and correction of chin retrusion versus a no-treatment control.
METHODS
Male and female subjects, aged 22 years or older, with mild to moderate chin retrusion, were randomized 3:1 to the hyaluronic acid filler Restylane Defyne ( n = 107) or no treatment ( n = 33). Assessments included live, blinded evaluations on a validated chin retrusion scale (Galderma Chin Retrusion Scale), aesthetic improvement (Global Aesthetic Improvement Scale), subject-reported FACE-Q Satisfaction with Chin, and safety follow-up.
RESULTS
Galderma Chin Retrusion Scale responder rate (≥1 grade improvement) was higher for the hyaluronic acid filler Restylane Defyne (81 percent) than for control (6 percent) ( p < 0.001) at week 12, and remained higher at week 48 (74 percent versus 11 percent; p < 0.001). Aesthetic improvement rates were high throughout the study as reported by investigators (≥96 percent) and subjects (≥85 percent). Subject satisfaction was higher in the hyaluronic acid filler Restylane Defyne group than in the control group at week 12 ( p < 0.001). In the individual FACE-Q scale items, 87 to 98 percent of subjects were satisfied at week 12. Treatment-related adverse events were mild to moderate.
CONCLUSIONS
The hyaluronic acid filler Restylane Defyne was safe and effective for augmentation of the chin region to improve the chin profile and associated with high aesthetic improvement and subject satisfaction. Effectiveness was sustained throughout 48 weeks.
CLINICAL QUESTION/LEVEL OF EVIDENCE
Therapeutic, II.
Topics: Male; Female; Humans; Hyaluronic Acid; Dermal Fillers; Cosmetic Techniques; Skin Aging; Chin; Treatment Outcome; Patient Satisfaction
PubMed: 36126213
DOI: 10.1097/PRS.0000000000009733 -
Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi... Dec 2023Orthodontics is a discipline that is based on aesthetics. It coordinates the relationship among nose, lip, and chin through the movement of teeth and the adjustment of... (Review)
Review
Orthodontics is a discipline that is based on aesthetics. It coordinates the relationship among nose, lip, and chin through the movement of teeth and the adjustment of jaw relationship. Orthodontists need to fully analyze the patient's soft tissue profile before treatment. They also need to analyze the existing problems and those that may be solved or caused during orthodontics to guide the design of orthodontic treatment and effectively improve the clinical effect of orthodontics. This article reviews the aesthetic preconditions that guide the design of orthodontic treatment from the perspective of orthodontists.
Topics: Humans; Esthetics, Dental; Orthodontics; Orthodontists; Chin; Nose
PubMed: 38597026
DOI: 10.7518/hxkq.2023.2023231 -
Tidsskrift For Den Norske Laegeforening... Feb 2022Numb chin syndrome describes sensory neuropathy characterised by numbness in the distribution of the terminal branch of the mandibular division of the trigeminal nerve....
BACKGROUND
Numb chin syndrome describes sensory neuropathy characterised by numbness in the distribution of the terminal branch of the mandibular division of the trigeminal nerve. This symptom may be overlooked by patients and clinicians due to its mild nature; however, it could represent a serious underlying pathology such as inflammatory conditions or malignancy.
CASE PRESENTATION
A man in his seventies presented with isolated numbness on the right side of the chin, and no other neurological or constitutional symptoms. Radiology showed a lytic mass in the right side of the mandible protruding through the mental foramen. A multidisciplinary approach revealed the cause of the patient's numb chin syndrome.
INTERPRETATION
This case report illustrates clinical considerations in a patient with numb chin syndrome.
Topics: Chin; Humans; Hypesthesia; Male; Neoplasms
PubMed: 35170922
DOI: 10.4045/tidsskr.21.0160 -
International Journal of Environmental... Jun 2020The chin is a unique anatomical landmark of modern humans. Its size and shape play an important role from the esthetic perspective. However, disagreement exists in the...
The chin is a unique anatomical landmark of modern humans. Its size and shape play an important role from the esthetic perspective. However, disagreement exists in the dental and anthropological literature regarding the sex differences in chin and symphysis morphometrics. The "sexual selection" theory is presented as a possible reason for chin formation in our species; however, many other contradictory theories also exist. This study's aims were therefore to determine how chin and symphysis size and shape vary with sex, and to discuss "sexual selection" theory as a reason for its formation. Head and neck computed tomography (CT) scans of 419 adults were utilized to measure chin and symphysis sizes and shapes. The chin and symphysis measures were compared between the sexes using an independent-samples -test, a Mann-Whitney test, and the F-statistic. The chin width was significantly greater in males than in females ( < 0.001), whereas the chin height, area, and size index were significantly greater in females ( < 0.001). Symphysis measures did not differ significantly between the sexes. Size accounted for 2-14% of the chin variance and between 24-33% of the symphysis variance. Overall, the chin was found to be a more heterogeneous anatomical structure than the symphysis, as well as more sexually dimorphic.
Topics: Adult; Chin; Female; Humans; Male; Mandible; Sex Characteristics; Tomography, X-Ray Computed
PubMed: 32545912
DOI: 10.3390/ijerph17124249 -
The Angle Orthodontist Nov 2008To test the hypothesis that there is no difference between the information produced by superimposition of serial lateral headfilms on anatomical structures and that...
OBJECTIVE
To test the hypothesis that there is no difference between the information produced by superimposition of serial lateral headfilms on anatomical structures and that produced by superimposition on metallic implants according to the protocols of Björk.
MATERIALS AND METHODS
Serial cephalograms of 10 untreated subjects who had tantalum implants placed in the maxilla and mandible during childhood were analyzed. Headfilms taken at six consecutive stages of cervical vertebral maturation (CS1-CS6) for six female and four male subjects were used. Tracings were superimposed according to the methods of superimpositions advocated by the American Board of Orthodontics (ABO). In addition, superimpositions along the inferior border of the mandible were performed. Finally, superimpositions of serial tracings on stable intraosseous implants were made to determine the actual growth and remodeling patterns of the maxilla and mandible.
RESULTS
The ABO maxillary superimposition method underestimates the vertical displacement and overestimates the forward movement of maxillary landmarks. Superimposing on the internal cortical outline of the symphysis and the inferior alveolar nerve canals generally approximates the mandibular superimposition on implants, although the lower anterior border of the symphysis may be a preferable area of superimposition. Superimposition on the lower border of the mandible does not reflect accurately the actual pattern of growth and remodeling of the mandible.
CONCLUSIONS
When analyzing serial headfilms, erroneous information concerning patterns of bone growth and remodeling can be obtained if convenient, but biologically incorrect superimposition protocols are used. In addition, tooth movements measured can be distorted significantly depending on the method of superimposition.
Topics: Age Determination by Skeleton; Bone Development; Bone Remodeling; Cephalometry; Cervical Vertebrae; Child; Chin; Dental Materials; Facial Bones; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Mandible; Mandibular Condyle; Maxilla; Nasal Bone; Palate; Prostheses and Implants; Skull; Tantalum
PubMed: 18947269
DOI: 10.2319/070107-301.1 -
Indian Pediatrics Aug 2015
Topics: Child, Preschool; Chin; Female; Humans; Jaw Diseases; Tremor
PubMed: 26388646
DOI: 10.1007/s13312-015-0706-y -
The Angle Orthodontist Sep 2017To determine if a new facial line (T), tangent to the throat, intersects the mandibular border in anterior (ANT) and posterior (POST) parts in proportions varying with...
OBJECTIVES
To determine if a new facial line (T), tangent to the throat, intersects the mandibular border in anterior (ANT) and posterior (POST) parts in proportions varying with facial configuration, and to evaluate the association between chin projection and throat inclination and the potential for the T-line to reflect this association.
MATERIALS AND METHODS
Measurements on profile photographs and cephalograms of 135 adults (aged 18-50 years)-45 each of Class I, II, and III (CI, CII, CIII) malocclusions-included ANT and POST, chin-throat (CTA), and mento-cervical (MCA) angles. Pre- and posttreatment measurements were compared in two subgroups (n = 25 each) of CII and CIII orthognathic surgery patients and in CII, division 1 early-treatment patients (n = 63). Statistics included analysis of variance and t-test for group differences, and Pearson correlation for associations among variables.
RESULTS
ANT was nearly equal to POST in CI (50.99%) and CIII (51.86%) subjects and shorter in CII (36.01%) subjects. CTA and MCA were greater in CII profiles and smaller in CIII profiles. Significant differences (P < .0001) were observed for ANT, POST, CTA, and MCA between Classes I/II and II/III and for MCA between Classes II/III (P = .016). High correlations were noted between ANT and CTA in Classes I (r = -0.83), II (r = -0.73), and III (r = -0.68). In surgically treated patients, posttreatment measurements approached CI values. In the early-treatment group, ANT increased but remained smaller than POST; CTA decreased by nearly 13%.
CONCLUSIONS
Chin-throat relations and chin extension are associated and require routine assessment in terms of diagnosis and treatment outcome. A practical tool to assess chin-throat relationship, the T-line bisects the mandibular body nearly equally in Class I faces.
Topics: Adolescent; Adult; Analysis of Variance; Anatomic Landmarks; Cephalometry; Chin; Face; Female; Humans; Male; Malocclusion; Mandible; Middle Aged; Neck; Orthodontics, Corrective; Orthognathic Surgery; Pharynx; Photography; Retrospective Studies; Treatment Outcome; Young Adult
PubMed: 28459284
DOI: 10.2319/100916-734.1 -
Brazilian Journal of Otorhinolaryngology 2016The esthetic balance of the face results from harmonic and symmetrical facial proportions. The literature describes several methods for lower-third facial analysis, but... (Review)
Review
INTRODUCTION
The esthetic balance of the face results from harmonic and symmetrical facial proportions. The literature describes several methods for lower-third facial analysis, but lacks a simple and practical method.
OBJECTIVE
To review the methods of analysis of the ideal projections of the chin based on soft tissues, showing the advantages and disadvantages of each.
METHODS
Literature review through the PubMed database.
RESULTS
The following methods for chin analysis based on soft tissues were reviewed: Gonzalles-Ulloa, Goode, Merrifield, Silver, Legan, Gibson & Calhoun, cervicomentual angle, and mentocervical angle.
CONCLUSION
An adequate analysis of the proportions of the face and facial disharmony is essential for the correct indication of the necessary procedures and good surgical outcome. The authors propose an algorithm to facilitate the indication for chin augmentation surgery.
Topics: Algorithms; Chin; Genioplasty; Humans
PubMed: 26832638
DOI: 10.1016/j.bjorl.2015.09.009