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The Journal of Clinical Pediatric... 2002Submersion occurs when a previously erupted tooth becomes embedded in the oral tissues. The purpose of this paper is to examine the distribution, the degree of...
Submersion occurs when a previously erupted tooth becomes embedded in the oral tissues. The purpose of this paper is to examine the distribution, the degree of re-impaction, the rate of congenital absence of the successor buds and the treatment in 28 submerged teeth in 17 patients.
Topics: Adolescent; Adult; Anodontia; Child; Dental Prosthesis; Female; Humans; Male; Mandible; Maxilla; Molar; Tooth Ankylosis; Tooth Diseases; Tooth Eruption; Tooth Extraction; Tooth, Deciduous; Tooth, Impacted
PubMed: 11990045
DOI: 10.17796/jcpd.26.3.05618l552p320552 -
Boletin Medico Del Hospital Infantil de... 2022Premature loss of deciduous teeth is the exfoliation or extraction before physiological replacement with < 50% or < 75% of the root of the substitute tooth formed or if...
BACKGROUND
Premature loss of deciduous teeth is the exfoliation or extraction before physiological replacement with < 50% or < 75% of the root of the substitute tooth formed or if there is > 1 mm of alveolar bone covering the permanent successor tooth organ. This study aimed to estimate the prevalence of premature tooth loss in children and identify associated factors in a health center in Acapulco, Guerrero.
METHODS
We conducted a cross-sectional study in which we collected information from 109 clinical records of children examined from January 2019 to August 2021. Sociodemographic data of the children and parents were collected: socioeconomic level, non-pathological personal history, and the history of premature deciduous tooth loss. Multivariate analysis to identify factors associated with premature deciduous tooth loss was performed with CIETmap statistical software. Odds ratio (OR) and 95% confidence interval (CI) were calculated to estimate the strength of the association.
RESULTS
The prevalence of premature loss of primary teeth was 40% (43/109). The leading cause was caries (84%, 36/43). The tooth organ with the highest loss occurrence was the lower right second molar (33%, 14/43). Gender was identified as an associated factor, with males having a higher risk of loss (ORa = 2.97; CI95% = 1.33-6.65).
CONCLUSIONS
Our results were similar to those reported in other studies. Strategies aimed at health promotion directed at parents and children should be reinforced.
Topics: Child; Male; Humans; Tooth, Deciduous; Cross-Sectional Studies; Prevalence; Molar; Tooth Loss
PubMed: 36264924
DOI: 10.24875/BMHIM.21000230 -
Indian Journal of Dental Research :... 2012Stem cells of the dental pulp are a population of postnatal stem cells with multilineage differentiation potential. These cells are derived from the neural... (Review)
Review
Stem cells of the dental pulp are a population of postnatal stem cells with multilineage differentiation potential. These cells are derived from the neural ectomesenchyme, similar to most craniofacial tissues, and specific niches in the pulp have been identified. Since the isolation of dental pulp stem cells (DPSC) and stem cells from exfoliating deciduous teeth (SHED), numerous studies have attempted to define and characterize these cells, and embryonic stem cell features have been reported in both DPSC and SHED. These cells have a vast repertoire of differentiation - osteogenic, odontogenic, myogenic, adipogenic, neurogenic, and melanocytic, and have even demonstrated transdifferentiation to corneal cells and islet cells of pancreas. The combined advantages of multipotency/pluripotency and the relative ease of access of pulp tissue for autologous use render DPSC/ SHED attractive options in regenerative dentistry and medicine. This review gives a bird's eye view of current knowledge with respect to stem cells from the dental pulp.
Topics: Cell Differentiation; Dental Pulp; Embryonic Stem Cells; Guided Tissue Regeneration; Humans; Multipotent Stem Cells; Pluripotent Stem Cells; Stem Cells; Tooth, Deciduous
PubMed: 23257502
DOI: 10.4103/0970-9290.104977 -
Forensic Science International Dec 2023This study investigates the preservation of DNA in different categories of teeth, including permanent and deciduous, fully developed and not fully developed, in both...
This study investigates the preservation of DNA in different categories of teeth, including permanent and deciduous, fully developed and not fully developed, in both adults and non-adults. Teeth were sampled from a modern-era cemetery in Ljubljana, Slovenia. DNA extraction was performed using a full demineralisation protocol. DNA quantity and quality were assessed using qPCR analyses, and autosomal STR typing was conducted to verify genetic profiles. Results revealed significant differences in DNA preservation among various tooth categories. Fully developed permanent teeth of adults exhibited the highest DNA yields, attributed to their fully developed roots and thicker cementum, which is rich in DNA. Deciduous teeth, with thinner enamel and cementum, showed lower DNA preservation regardless of developmental stage. Non-adult teeth generally yielded less DNA compared to adults, even when considering only fully developed permanent teeth, indicating factors beyond developmental stage. These findings suggest that, in archaeological and forensic contexts, researchers should prioritize fully developed permanent teeth for DNA analysis due to their superior preservation. Additionally, this study underscores the importance of considering tooth type and developmental stage when selecting samples for genetic analysis in cases where petrous bone is unavailable, expanding our understanding of DNA preservation in human remains.
Topics: Humans; Adult; Tooth, Deciduous; Dentition, Permanent; Forensic Medicine; DNA; Slovenia
PubMed: 37979239
DOI: 10.1016/j.forsciint.2023.111882 -
Journal of Applied Oral Science :... 2011SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential... (Review)
Review
SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin.
Topics: Cell Differentiation; Dental Pulp; Dentistry; Humans; Stem Cells; Tissue Engineering; Tooth, Deciduous
PubMed: 21625731
DOI: 10.1590/s1678-77572011000300002 -
Tissue Engineering. Part B, Reviews Apr 2012Dental pulp from deciduous (baby) teeth, which are discarded after exfoliation, represents an advantageous source of young stem cells. Herein, we discuss the methods of... (Review)
Review
Dental pulp from deciduous (baby) teeth, which are discarded after exfoliation, represents an advantageous source of young stem cells. Herein, we discuss the methods of deciduous teeth stem cell (DTSC) isolation and cultivation. We show that based on these methods, at least three different stem cell populations can be identified: a population similar to bone marrow-derived mesenchymal stem cells, an epithelial stem-like cells, and/or a mixed population composed of both cell types. We analyzed the embryonic origin and stem cell niche of DTSCs with respect to the advantages they can provide for their future use in cell therapies and regenerative medicine. In vitro and in vivo differentiation of the DTSC populations, their developmental potential, immunological compatibility, tissue engineering, and transplantation use in studies in animal models are also the focus of the current report. We briefly describe the derivation of induced pluripotent stem (iPS) cells from DTSCs, which can be obtained more easily and efficiently in comparison with human fibroblasts. These iPS cells represent an interesting model for the investigation of pediatric diseases and disorders. The importance of DTSC banking is also discussed.
Topics: Animals; Dental Pulp; Humans; Immunophenotyping; Stem Cell Niche; Stem Cells; Telomere; Tooth, Deciduous
PubMed: 22032258
DOI: 10.1089/ten.TEB.2011.0327 -
Anatomical Record (Hoboken, N.J. : 2007) Sep 2020Previous descriptive work on deciduous dentition of primates has focused disproportionately on great apes and humans. To address this bias in the literature, we studied... (Comparative Study)
Comparative Study
Previous descriptive work on deciduous dentition of primates has focused disproportionately on great apes and humans. To address this bias in the literature, we studied 131 subadult nonhominoid specimens (including 110 newborns) describing deciduous tooth morphology and assessing maximum hydroxyapatite density (MHD). All specimens were CT scanned at 70 kVp and reconstructed at 20.5-39 μm voxels. Grayscale intensity from scans was converted to hydroxyapatite (HA) density (mg HA/cm ) using a linear conversion of grayscale values to calibration standards of known HA density (R = .99). Using Amira software, mineralized dental tissues were captured by segmenting the tooth cusps first and then capturing the remainder of the teeth at descending thresholds of gray levels. We assessed the relationship of MHD of selected teeth to cranial length using Pearson correlation coefficients. In monkeys, anterior teeth are more mineralized than postcanine teeth. In tarsiers and most lemurs and lorises, postcanine teeth are the most highly mineralized. This suggests that monkeys have a more prolonged process of dental mineralization that begins with incisors and canines, while mineralization of postcanine teeth is delayed. This may in part be a result of relatively late weaning in most anthropoid primates. Results also reveal that in lemurs and lorises, MHD of the mandibular first permanent molar (M ) negatively correlates with cranial length. In contrast, the MHD of M positively correlates with cranial length in monkeys. This supports the hypothesis that natural selection acts independently on dental growth as opposed to mineralization and indicates clear phylogenetic differences among primates.
Topics: Anatomy, Comparative; Animals; Animals, Newborn; Calcification, Physiologic; Phylogeny; Primates; Tooth; Tooth, Deciduous
PubMed: 31802627
DOI: 10.1002/ar.24326 -
Environmental Research Oct 2015Epidemiological evidence supports associations between prenatal exposure to environmental organic chemicals and childhood health impairments. Unlike the common choice of... (Review)
Review
Epidemiological evidence supports associations between prenatal exposure to environmental organic chemicals and childhood health impairments. Unlike the common choice of biological matrices such as urine and blood that can be limited by short half-lives for some chemicals, teeth provide a stable repository for chemicals with half-life in the order of decades. Given the potential of the tooth bio-matrix to study long-term exposures to environmental organic chemicals in human biomonitoring programs, it is important to be aware of possible pitfalls and potential opportunities to improve on the current analytical method for tooth organics analysis. We critically review previous results of studies of this topic. The major drawbacks and challenges in currently practiced concepts and analytical methods in utilizing tooth bio-matrix are (i) no consideration of external (from outer surface) or internal contamination (from micro-odontoblast processes), (ii) the misleading assumption that whole ground teeth represent prenatal exposures (latest formed dentine is lipid rich and therefore would absorb and accumulate more organic chemicals), (iii) reverse causality in exposure assessment due to whole ground teeth, and (iv) teeth are a precious bio-matrix and grinding them raises ethical concerns about appropriate use of a very limited resource in exposure biology and epidemiology studies. These can be overcome by addressing the important limitations and possible improvements with the analytical approach associated at each of the following steps: (i) tooth sample preparation to retain exposure timing, (ii) organics extraction and pre-concentration to detect ultra-trace levels of analytes, (iii) chromatography separation, (iv) mass spectrometric detection to detect multi-class organics simultaneously, and (v) method validation, especially to exclude chance findings. To highlight the proposed improvements we present findings from a pilot study that utilizes tooth matrix biomarkers to obtain trimester-specific exposure information for a range of organic chemicals.
Topics: Biomarkers; Environmental Monitoring; Environmental Pollutants; Female; Humans; Organic Chemicals; Pregnancy; Prenatal Exposure Delayed Effects; Tooth, Deciduous
PubMed: 26219084
DOI: 10.1016/j.envres.2015.06.032 -
Archives of Disease in Childhood Oct 1957
Topics: Humans; Tooth, Deciduous
PubMed: 13479141
DOI: 10.1136/adc.32.165.386 -
Revue Medicale de Liege Dec 2016Preserving primary teeth is crucial for maintaining the maxillary growth, aesthetics, mastication, and speech and for preventing from abnormal habits. Given the peculiar... (Review)
Review
Preserving primary teeth is crucial for maintaining the maxillary growth, aesthetics, mastication, and speech and for preventing from abnormal habits. Given the peculiar anatomy of the primary tooth, caries grow faster and more frequently to the pulp. In pediatric dentistry, new methods and enhanced material have been recently released on the market and broadened the field of treatments. In this paper, we review the pulp diseases affecting children and focus on the current root canal therapies that favour the physiological primary tooth loss.
Topics: Child; Dental Pulp; Dental Pulp Diseases; Humans; Tooth, Deciduous
PubMed: 28387098
DOI: No ID Found