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Ugeskrift For Laeger Feb 2017Micrographic surgery is currently the only technique which ensures complete removal of basal cell carcinomas. The major limitation is the high set-up cost, which is... (Review)
Review
Micrographic surgery is currently the only technique which ensures complete removal of basal cell carcinomas. The major limitation is the high set-up cost, which is particularly connected with specialized training of surgeons, technicians and the set-up of a histology facility for frozen tissue sectioning and staining. In the long run, however, the cost of Mohs surgery per patient does not exceed that of conventional surgery. The technique is very safe and has multiple advantages over any other treatment modality. It achieves the highest cure rates, it is minimally invasive, it is tissue-sparing and it enables the optimal closure of the surgical defect. Mohs surgery is cost-effective, especially when dealing with poorly demarcated, high-risk, facial tumours, where it should be considered as the first choice of treatment.
Topics: Carcinoma, Basal Cell; Facial Neoplasms; Humans; Mohs Surgery; Skin Neoplasms
PubMed: 28397683
DOI: No ID Found -
Anais Brasileiros de Dermatologia 2017
Topics: Aged; Biopsy; Erythema; Facial Neoplasms; Fatal Outcome; Female; Hemangiosarcoma; Humans; Immunohistochemistry; Skin; Skin Neoplasms
PubMed: 28538905
DOI: 10.1590/abd1806-4841.20175865 -
Dermatology (Basel, Switzerland) 1996Apocrine hidrocystoma is a cyst from the secretory portion of the apocrine sweat gland and tends to occur as a solitary facial lesion. We report a 66-year-old woman with...
Apocrine hidrocystoma is a cyst from the secretory portion of the apocrine sweat gland and tends to occur as a solitary facial lesion. We report a 66-year-old woman with multiple, cystic lesions on her face. Histopathology revealed cystic spaces lined by a row of secretory cells showing decapitation secretion. We emphasize the multiple character of the case and discuss its distinction from so-called eccrine hidrocystomas.
Topics: Aged; Apocrine Glands; Eccrine Glands; Eosinophils; Epithelium; Facial Neoplasms; Female; Hidrocystoma; Humans; Skin Neoplasms
PubMed: 8884157
DOI: 10.1159/000246235 -
The British Journal of Ophthalmology Sep 2005
Topics: Facial Neoplasms; Hemangioma; Humans; Infant, Newborn; Infant, Premature; Skin Neoplasms
PubMed: 16113350
DOI: 10.1136/bjo.2005.073411 -
Actas Dermo-sifiliograficas 2014Facial angiofibromas are hamartomatous growths that are closely associated with tuberous sclerosis complex and, in fact, they constitute one of the main diagnostic... (Review)
Review
Facial angiofibromas are hamartomatous growths that are closely associated with tuberous sclerosis complex and, in fact, they constitute one of the main diagnostic criteria for that disease. These lesions composed of blood vessels and fibrous tissue appear on the face at an early age. Since they have important physical and psychological repercussions for patients, several treatment options have been used to remove them or improve their appearance. However, the lack of treatment guidelines prevents us from developing a common protocol for patients with this condition. The present article aims to review the treatments for facial angiofibromas used to date and to propose a new evidence-based treatment protocol.
Topics: Algorithms; Angiofibroma; Antibiotics, Antineoplastic; Facial Neoplasms; Humans; Sirolimus; Skin Neoplasms
PubMed: 23522741
DOI: 10.1016/j.ad.2012.11.020 -
American Family Physician Apr 2020
Topics: Carcinoma, Basal Cell; Facial Neoplasms; Female; Humans; Middle Aged; Physical Examination; Risk Factors; Skin Neoplasms
PubMed: 32227828
DOI: No ID Found -
JAMA Facial Plastic Surgery Dec 2019Objectively measuring how Mohs defect reconstruction changes casual observer attention has important implications for patients and facial plastic surgeons. (Observational Study)
Observational Study
IMPORTANCE
Objectively measuring how Mohs defect reconstruction changes casual observer attention has important implications for patients and facial plastic surgeons.
OBJECTIVE
To use eye-tracking technology to objectively measure the ability of Mohs facial defect reconstruction to normalize facial attention.
DESIGN, SETTING, AND PARTICIPANTS
This observational outcomes study was conducted at an academic tertiary referral center from January to June 2016. An eye-tracking system was used to record how 82 casual observers directed attention to photographs of 32 patients with Mohs facial defects of varying sizes and locations before and after reconstruction as well as 16 control faces with no facial defects. Statistical analysis was performed from November 2018 to January 2019.
MAIN OUTCOMES AND MEASURES
First, the attentional distraction caused by facial defects was quantified in milliseconds of gaze time using eye tracking. Second, the eye-tracking data were analyzed using mixed-effects linear regression to assess the association of facial defect reconstruction with normalized facial attention.
RESULTS
The 82 casual observers (63 women and 19 men; mean [SD] age, 34 [12] years) viewed control faces in a similar and consistent fashion, with most attention (65%; 95% CI, 62%-69%) directed at the central triangle, which includes the eyes, nose, and mouth. The eyes were the most visually important feature, capturing a mean of 60% (95% CI, 57%-64%) of fixation time within the central triangle and 39% (95% CI, 36%-43%) of total observer attention. The presence of Mohs defects was associated with statistically significant alterations in this pattern of normal facial attention. The larger the defect and the more centrally a defect was located, the more attentional distraction was observed, as measured by increased attention on the defect and decreased attention on the eyes, ranging from 729 (95% CI, 526-931) milliseconds for small peripheral defects to 3693 (95% CI, 3490-3896) milliseconds for large central defects. Reconstructive surgery was associated with improved gaze deviations for all faces and with normalized attention directed to the eyes for all faces except for those with large central defects.
CONCLUSIONS AND RELEVANCE
Mohs defects are associated with altered facial perception, diverting attention from valuable features such as the eyes. Reconstructive surgery was associated with normalized attentional distraction for many patients with cutaneous Mohs defects. These data are important to patients who want to know how reconstructive surgery could change the way people look at their face. The data also point to the possibility of outcomes prediction based on facial defect size and location before reconstruction. Eye tracking is a valuable research tool for outcomes assessment that lays the foundation for understanding how reconstructive surgery may change perception and normalize facial deformity.
Topics: Adult; Attention; Eye Movements; Facial Neoplasms; Female; Humans; Male; Mohs Surgery; Photography; Plastic Surgery Procedures
PubMed: 31670742
DOI: 10.1001/jamafacial.2019.1072 -
Romanian Journal of Morphology and... 2018The face is an unfortunate location for any type of tumor - malignant or not - with significant esthetic and functional outcomes. To reconstruct a facial defect may seem...
PURPOSE
The face is an unfortunate location for any type of tumor - malignant or not - with significant esthetic and functional outcomes. To reconstruct a facial defect may seem simple, but can be rather complicated. The aim of this study is to analyze and discuss our results in order to conclude with specific surgical strategies correlated with the morphopathological results. The most important objective for us is to offer the highest level of expertise to our patients and to prove that the symbiosis between the surgical treatment and the work of the Department of Morphopathology is essential in order to maximize the quality of medical care provided for our patients.
PATIENTS, MATERIALS AND METHODS
A retrospective study was conducted on 116 patients diagnosed with facial malignant tumors, 70 of which were confirmed as basal cell carcinomas (BCCs), 35 confirmed as squamous cell carcinomas (SCCs) and 11 malignant melanomas (MMs). Most BCC cases (57) showed ulceration, with a long clinical evolution (more than 10 years) in 48 cases. Only in 12 SCC cases, patients showed inflammation and ulceration, with a shorter evolution period (2-5 years). For complete microscopic diagnosis, immunohistochemical (IHC) examination was necessary in 46 cases. The BCC "deceiving" clinical behavior and the generally aggressive character of the MM were found in our patients as well.
RESULTS
The most frequent sites were the orbital region (27 cases) and the nasolabial sulcus (26 cases). In order to reconstruct the postexcisional defects, we had to perform local flaps in 62 cases (14 frontal flaps for orbital defects, 32 glabellar flaps for medial epicanthus, lower lid and nasal region, 15 nasolabial flaps for lower lid or nasal alae and one "Z"-plasty for the submental region). Oncological follow-up was performed in all patients and in 15 cases re-excision was necessary (11 BCCs, two SCCs and two MMs). Cervical lymph node metastasis occurred in six cases (three BCCs, one SCC and two MMs).
CONCLUSIONS
The cooperation between surgeons and pathologists allowed for good outcomes and the pathology examination can guide the surgical approach towards better results both functionally and esthetically.
Topics: Carcinoma, Squamous Cell; Facial Neoplasms; Female; Humans; Male; Plastic Surgery Procedures; Retrospective Studies
PubMed: 29940639
DOI: No ID Found -
American Family Physician Nov 2015
Topics: Aged; Carcinoma, Squamous Cell; Diagnosis, Differential; Facial Neoplasms; Female; Humans; Keratoacanthoma; Nevus, Sebaceous of Jadassohn
PubMed: 26554287
DOI: No ID Found -
African Journal of Paediatric Surgery :... 2021Facial teratomas are uncommon tumours in children that distort the face and may be associated with functional problems. They are less common than cervical teratomas... (Review)
Review
Facial teratomas are uncommon tumours in children that distort the face and may be associated with functional problems. They are less common than cervical teratomas though they are often grouped together and considered an emergency due to their tendency to cause respiratory compromise. They tend to be large and cause cosmetic issues; hence usually noticed early and medical help sought promptly by parents. The close proximity of facial teratomas to structures like eyes, parotid gland, facial nerve, vessels and brain makes them challenging and requires a patient and meticulous exploration during surgery. We present a case of an 11 month old girl with left sided temporal teratoma. Well planning of the incision and complete excision of the tumour with careful sparing of the facial nerves and parotid gland yielded good result.
Topics: Facial Neoplasms; Female; Humans; Infant; Teratoma
PubMed: 33642408
DOI: 10.4103/ajps.AJPS_77_20