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The Indian Journal of Medical Research Jan 2015
Topics: Amino Acids, Diamino; Humans; Lathyrism; Lathyrus; Neurotoxins; Seeds
PubMed: 25857507
DOI: 10.4103/0971-5916.154519 -
The Indian Medical Gazette Feb 1918
PubMed: 29008596
DOI: No ID Found -
The Indian Medical Gazette Jul 1939
PubMed: 29011826
DOI: No ID Found -
The American Journal of Tropical... Mar 2021Lathyrism is an incurable neurological disorder, resulting from excessive consumption of grass pea (Lathyrus sativus), which clinically manifests as paralysis of lower...
Lathyrism is an incurable neurological disorder, resulting from excessive consumption of grass pea (Lathyrus sativus), which clinically manifests as paralysis of lower limbs. Because of the high production of grass peas, a large number of people are expected to be affected by the disease in Northeast Ethiopia. However, there is no comprehensive study that quantified the magnitude of the problem. Therefore, in this study, we determined the prevalence of lathyrism and socioeconomic disparities in Northeast Ethiopia. A community-based cross-sectional study was used which used a quantitative method of data collection from January to February 2019. Data were collected from a total of 2,307 inhabitants in the study area using structured questionnaires. Lathyrism cases were identified using a case definition of symmetrical spastic leg weakness, and subacute or insidious onset, with no sensory deficit, and with a history of grass pea consumption before and at the onset of paralysis. The majority (56.8%) of participants were male, and 34.7% were aged 45 years or older. Overall, the prevalence of lathyrism was 5.5%, and it was higher in males (7.9%) than in females (2.5%). Moreover, the prevalence was higher among farmers (7.0%) than merchants (0.3%), very poor economic status (7.2%) than very rich (1.1%), who produced (9.6%) grass pea than not produced (0.9%), and those who used clay pottery (6.2%) than metal (4.8%) for cooking. The prevalence of lathyrism in Northeast Ethiopia is remarkably high. Therefore, we recommend lathyrism to be among the list of reportable health problems and incorporated in the national routine surveillance system.
Topics: Cooking; Cross-Sectional Studies; Ethiopia; Female; Foodborne Diseases; Humans; Lathyrism; Lathyrus; Lower Extremity; Male; Middle Aged; Paralysis; Prevalence; Public Health; Socioeconomic Factors; Surveys and Questionnaires
PubMed: 33684061
DOI: 10.4269/ajtmh.20-1480 -
The Indian Medical Gazette Sep 1893
PubMed: 29001151
DOI: No ID Found -
Proceedings of the Royal Society of... Apr 1969
Review
Topics: Adolescent; Adult; Beriberi; Child; Cyanides; Environmental Exposure; Female; Foodborne Diseases; Humans; Jamaica; Lathyrism; Leprosy; Male; Manihot; Nervous System Diseases; Nigeria; Nutrition Disorders; Pregnancy; Racial Groups; Senegal; Syphilis; Tropical Medicine; Vitamin B 12
PubMed: 4897832
DOI: No ID Found -
The Indian Journal of Medical Research Nov 2018Since the first report of lathyrism in 1926, the ICMR-National Institute of Nutrition (NIN) at Hyderabad, India, has made tremendous contributions in the field of food... (Review)
Review
Since the first report of lathyrism in 1926, the ICMR-National Institute of Nutrition (NIN) at Hyderabad, India, has made tremendous contributions in the field of food toxins/food safety for the benefit of the people. The present article highlights the Institute's work on various food toxins/foodborne diseases since its inception and discusses the important contributions made in the context of public health protection that formed the basis for several national policies on their prevention and control. The investigations on food toxins, in the initial decades, were limited to the description of lathyrism and its endemicity. Subsequently, the horizon was broadened to include the problem of mycotoxins and mycotoxicosis, which had received global attention and variety of other disease outbreaks investigations leading to total food safety transition in the forthcoming decades. Important contributions in epidemiological investigations, reproduction of the disease in experimental animals, surveillance and monitoring studies, development of methods for detection of food toxins and contaminants, evolving strategies for prevention and control and developing the concept of risk assessment and risk management for addressing food safety issues in the country are discussed.
Topics: Dietary Exposure; Food Safety; Foodborne Diseases; Humans; India; Public Health; Risk Assessment; Risk Management
PubMed: 30666975
DOI: 10.4103/ijmr.IJMR_1692_18 -
Proceedings of the Royal Society of... Aug 1966
Review
Topics: Animals; Chick Embryo; Collagen; Female; Lathyrism; Pregnancy; Pregnancy, Animal; Rats
PubMed: 5331025
DOI: No ID Found -
The Indian Medical Gazette Feb 1903
PubMed: 29002974
DOI: No ID Found