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Swiss Dental Journal 2015Local anaesthetics are an integral part of most dental procedures and are therefore widely used and safely applied. Though rare, complications may occur and can be...
Local anaesthetics are an integral part of most dental procedures and are therefore widely used and safely applied. Though rare, complications may occur and can be categorized as local or systemic. In the majority they are of minor nature but there is a potential for severe and possibly lethal side effects. Local complications are nerve damage (mainly the lingual and the inferior alveolar nerve), lesions of vascular structures, hematoma formation, temporary palsy of the facial nerve and post injection pain being the most common local complication. Examples for systemic complications are allergic reactions, cardiovascular complications, intoxication and psychogenic reactions.
PubMed: 26470804
DOI: No ID Found -
Journal of Clinical Medicine Nov 2022A study has shown that 19-34% of patients with diabetes will develop a foot ulcer in their lifetime [...].
A study has shown that 19-34% of patients with diabetes will develop a foot ulcer in their lifetime [...].
PubMed: 36362790
DOI: 10.3390/jcm11216562 -
PLoS Medicine Apr 2007This month's article by Koniaris and colleagues provides further evidence that lethal injection is far from humane. The editors call on the US to abandon the death...
This month's article by Koniaris and colleagues provides further evidence that lethal injection is far from humane. The editors call on the US to abandon the death penalty.
Topics: Capital Punishment; Ethics; Humans; Injections; Pharmaceutical Preparations; United States
PubMed: 17570744
DOI: 10.1371/journal.pmed.0040171 -
Tzu Chi Medical Journal 2023Intracerebral hemorrhage (ICH) is the most lethal type of cerebral stroke without effective therapy. Although clinical trials with various surgeries have been conducted,... (Review)
Review
Intracerebral hemorrhage (ICH) is the most lethal type of cerebral stroke without effective therapy. Although clinical trials with various surgeries have been conducted, none have improved clinical outcomes compared to the current medical management for ICH. Several ICH animal models, including autologous blood injection, collagenase injection, thrombin injection, and microballoon inflation methods, have been developed to elucidate the underlying mechanisms of ICH-induced brain injury. These models could also be used for discovering new therapy for ICH preclinically. We summarize the existing ICH animal models and the evaluation parameters used to measure the disease outcomes. We conclude that these models, resembling the different aspects of ICH pathogenesis, have their advantages and disadvantages. None of the current models closely represent the severity of ICH seen in clinical settings. More appropriate models are needed to streamline ICH's clinical outcomes and be used for validating newly developed treatment protocols.
PubMed: 36866349
DOI: 10.4103/tcmj.tcmj_119_22 -
BMJ (Clinical Research Ed.) Aug 1992
Topics: Capital Punishment; Ethics, Medical; Human Rights; Humans; Physicians; Professional Practice
PubMed: 1392916
DOI: 10.1136/bmj.305.6850.381 -
Journal of Family Medicine and Primary... Jan 2024The word "Euthanasia" relates to two different words from the Greek language "Eu which indicates good and Thanatosis which indicates death", suggesting a "satisfactory... (Review)
Review
INTRODUCTION
The word "Euthanasia" relates to two different words from the Greek language "Eu which indicates good and Thanatosis which indicates death", suggesting a "satisfactory Death" or "easy and painless Death" The phrase "mercy killing" has become associated with this meaning. It comprises inflicting painless death on a person suffering from an incurable and dreadful illness. It's the practice of terminating a person's life by administering a lethal injection or ceasing medical treatment. Informed and shared decision-making between the patient and the health professional caring for him or her is crucial for the quality of care and its outcomes. Living wills are nothing more than a tangible representation of this truth. As a result of their legal approval, patients' autonomy has been recognized. However, there are some differences in the regulations that have been adopted, and the health practice linked with these documents raises a number of practical and ethical questions that should be considered.
MATERIALS AND METHODS
PUBMED and COCHRANE databases were searched, with no language constraints, up to July 2021. Trial registration studies, hand searching, and bibliographic references of pertinent literature were also checked. Individual authors were responsible for data collection and analysis. The studies were evaluated independently by three review authors.
CONCLUSION
A thorough assessment of the current accessible literature on living will be conducted, just to focus on the knowledge of euthanasia in detail. Most importantly, the social impact of the concept of euthanasia needs to be understood by the society. Moreover, it must be considered that euthanasia is different from suicide. Few communities may show the interference of their religion with euthanasia. So it is essential to enlighten the idea of euthanasia in legal ways for different countries.
PubMed: 38482288
DOI: 10.4103/jfmpc.jfmpc_482_22 -
CMAJ : Canadian Medical Association... Jun 2012
Topics: Abortion, Induced; Capital Punishment; Female; Fetus; Humans; Male; Pregnancy; Sex Determination Analysis; Sex Preselection
PubMed: 22690013
DOI: 10.1503/cmaj.112-2044 -
The American Journal of Pathology Oct 1972Studies conducted to gain insight into the pathogenesis of experimental aspergillosis indicated that mice pretreated with cortisone acetate and then injected...
Studies conducted to gain insight into the pathogenesis of experimental aspergillosis indicated that mice pretreated with cortisone acetate and then injected intraperitoneally with nongerminating spores of Aspergillus flavus developed a high incidence of lethal visceral hyphal aspergillosis. A similar, high incidence of fatal infections was observed in cortisone-treated animals in which the number of peritoneal macrophages had been increased by prior injection of thioglycollate. To determine whether germination of spores within the host was important to the subsequent development of disseminated hyphal aspergillosis, germinating spores of A flavus were injected intraperitoneally into normal animals. While a similar dose of nongerminating spores, administered intraperitoneally into normal mice, induced a low incidence of lethal injection, germinating spores induced a high incidence of fatal disease associated with widely disseminated visceral hyphal aspergillosis. Our studies indicate that phagocytic cells in the peritoneal cavity of normal mice are able to ingest nonperminating spores of A flavus and kill them, preventing germination. However, the phagocytic cells are unable to cope with early germinating spores, which then continue to proliferate, leading to extensive hyphal invasion of visceral organs and death.
Topics: Adrenal Glands; Animals; Aspergillosis; Aspergillus flavus; Cortisone; Female; Kidney; Lung; Mice; Pancreas; Phagocytosis; Spleen; Spores, Fungal; Stomach; Thioglycolates
PubMed: 4628112
DOI: No ID Found