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Sensors (Basel, Switzerland) Feb 2022Real-time location systems (RTLS) record locations of individuals over time and are valuable sources of spatiotemporal data that can be used to understand patterns of... (Review)
Review
Real-time location systems (RTLS) record locations of individuals over time and are valuable sources of spatiotemporal data that can be used to understand patterns of human behaviour. Location data are used in a wide breadth of applications, from locating individuals to contact tracing or monitoring health markers. To support the use of RTLS in many applications, the varied ways location data can describe patterns of human behaviour should be examined. The objective of this review is to investigate behaviours described using indoor location data, and particularly the types of features extracted from RTLS data to describe behaviours. Four major applications were identified: health status monitoring, consumer behaviours, developmental behaviour, and workplace safety/efficiency. RTLS data features used to analyse behaviours were categorized into four groups: dwell time, activity level, trajectory, and proximity. Passive sensors that provide non-uniform data streams and features with lower complexity were common. Few studies analysed social behaviours between more than one individual at once. Less than half the health status monitoring studies examined clinical validity against gold-standard measures. Overall, spatiotemporal data from RTLS technologies are useful to identify behaviour patterns, provided there is sufficient richness in location data, the behaviour of interest is well-characterized, and a detailed feature analysis is undertaken.
Topics: Computer Systems; Contact Tracing; Humans
PubMed: 35161964
DOI: 10.3390/s22031220 -
Chinese Neurosurgical Journal Aug 2022Spinal extradural meningeal cysts (SEMCs) are rare lesions of the spinal canal. Although closure of the dural defect can achieve satisfactory therapeutic effects,... (Review)
Review
Spinal extradural meningeal cysts (SEMCs) are rare lesions of the spinal canal. Although closure of the dural defect can achieve satisfactory therapeutic effects, locating the fistula is difficult. This review summarizes the methods for locating the fistula of SEMCs and the distribution and features of fistula sites.This was a non-systematic literature review of studies on SEMCs. We searched PubMed for English-language articles to summarize the methods of locating the defect. The search words were "epidural arachnoid cyst," "dural cyst," "epidural cyst," and "epidural meningeal cyst." For the defect location component of the study, case reports, studies with a sample size less than four, controversial ventral dural dissection(s), and undocumented fistula location reports were excluded.Our review showed that radiography and computed tomography (CT) may show changes in the bony structure of the spine, with the largest segment of change indicating the fistula site. Occasionally, magnetic resonance imaging (MRI) can show a cerebrospinal fluid (CSF) flow void at the fistula site. The middle segment of the cyst on sagittal MRI, the largest cyst area, and cyst laterality in the axial view indicate the fistula location. Myelography can show the fistula location in the area of the enhanced cyst and subarachnoid stenosis. Digital subtraction or delayed CT can be used to observe the location of the initial cyst filling. Cine MRI and time-spatial labeling inversion pulse techniques can be used to observe CSF flow. Steady-state image construction interference sequence MRI has a high spatial resolution. Neuroendoscopy, MRI myelography, and ultrasound fistula detection can be performed intraoperatively. Moreover, the fistula was located most often in the T12-L1 segment.Identifying the fistula location is difficult and requires a combination of multiple examinations and experience for comprehensive judgment.
PubMed: 36045421
DOI: 10.1186/s41016-022-00291-3 -
BMC Health Services Research Nov 2022Pharmacists in Canada are assuming an increasingly important role in the provision of primary care services. This raises questions about access to pharmacy services...
BACKGROUND
Pharmacists in Canada are assuming an increasingly important role in the provision of primary care services. This raises questions about access to pharmacy services among those with medical care needs. While there is evidence on proximity of residents of Ontario and Nova Scotia to community pharmacies, there is little evidence for the rest of Canada. I thus measured the availability of pharmacist services, both the number of community pharmacies and their hours of operation, at both the provincial and sub-provincial level in Canada. Next, I measured associations of indicators of medical need and the availability of pharmacist services across sub-provincial units.
METHODS
I collected data, for each Forward Sortation Area (FSA), on medical need, measured using the fraction of residents aged 65 + and median household income, and pharmacist service availability (the number of community pharmacies and their hours of operation, divided by the FSA population). Linear regression methods were used to assess associations of FSA-level service availability and medical need.
RESULTS
There are between 2.0 and 3.3 community pharmacies per 10,000 population, depending on the province. There are also provincial variations in the number of hours that pharmacies are open. Quebec pharmacies were open a median of 75 h a week. In Manitoba, pharmacies were open a median of 53 h a week. The per capita number of pharmacies and their total hours of operation at the FSA level tend to be higher in less affluent regions and in which the share of residents is aged 65 or older. Provincial differences in pharmacy availability were still evident after controlling for medical need.
CONCLUSION
Community pharmacies in Canada tend to locate where indicators of health needs are greatest. The impact on patient health outcomes of these pharmacy locational patterns remains an area for future research.
Topics: Humans; Pharmacies; Community Pharmacy Services; Pharmacists; Pharmacy; Nova Scotia
PubMed: 36329439
DOI: 10.1186/s12913-022-08709-5 -
Folia Neuropathologica 2022Tumour-to-meningioma metastasis (TTMM) is an uncommon phenomenon, however repeatedly found in the literature. Meningiomas occur to be the most frequent target of... (Review)
Review
Tumour-to-meningioma metastasis (TTMM) is an uncommon phenomenon, however repeatedly found in the literature. Meningiomas occur to be the most frequent target of metastatic expansion of systemic cancers. Meningiomas often vary in symptoms and treatment, and this largely depends on the tumour location. Due to their variable locations, they can be classified as convexity meningiomas, which includes falcine and parasagittal tumours, and cranial base, which includes tumours located in the olfactory groove, sphenoid wing, petrous bone and other cranial base locations. The aim of this study was to analyse all data regarding metastases to cranial base meningiomas. We performed a literature search to locate all cases of metastases to cranial base meningiomas in PubMed and Medline databases using the following key words: metastasis to meningioma, meningioma metastasis, and cranial base meningioma. We collected patient and cancer parameters, exact meningioma location and clinical presentations including characteristics which may suggest TTMM. We found 100 articles describing 111 patients of metastasis to cranial base meningioma. Among these articles, 55 cases (49.55%) included metastases to non-skull base meningiomas. In 24 cases (21.62%), the location of meningioma was not precisely described or other data were unavailable, in particular histopathological examination. The most common location of TTMM was sphenoid wing, which was found in 9 patients. The other locations included cerebellopontine angle in 5 patients, and tuberculum sellae in 3 cases. 81.25% cases of TTMM were reported in women, and the most common cancer origins were the breast (28.3%), lung (18.7%), kidney (9.38%) and prostate (9.38%). In two cases the metastatic origin was unclear, and in 15.6% of cases the patients were in remission for more than 1 year. In 78.1% of cases patients presented focal deficits, followed by increased intracranial pressure, and seizures. In almost one-third of cases, TTMM first appeared from a previously unknown cancer. Rapid clinical presentation of cranial nerve palsies may suggest the dual nature of intracranial pathology. The metastasis to cranial base meningioma should be suspected in patients with oncological background, regardless of meningioma parameters or cancer status.
Topics: Male; Humans; Female; Meningeal Neoplasms; Meningioma; Skull Base Neoplasms; Skull Base; Treatment Outcome
PubMed: 36734379
DOI: 10.5114/fn.2022.123500 -
Frontiers in Neuroscience 2021Functional neurosurgery requires neuroimaging technologies that enable precise navigation to targeted structures. Insufficient image resolution of deep brain structures...
Functional neurosurgery requires neuroimaging technologies that enable precise navigation to targeted structures. Insufficient image resolution of deep brain structures necessitates alignment to a brain atlas to indirectly locate targets within preoperative magnetic resonance imaging (MRI) scans. Indirect targeting through atlas-image registration is innately imprecise, increases preoperative planning time, and requires manual identification of anterior and posterior commissure (AC and PC) reference landmarks which is subject to human error. As such, we created a deep learning-based pipeline that consistently and automatically locates, with submillimeter accuracy, the AC and PC anatomical landmarks within MRI volumes without the need for an atlas. Our novel deep learning pipeline (DeepNavNet) regresses from MRI scans to heatmap volumes centered on AC and PC anatomical landmarks to extract their three-dimensional coordinates with submillimeter accuracy. We collated and manually labeled the location of AC and PC points in 1128 publicly available MRI volumes used for training, validation, and inference experiments. Instantiations of our DeepNavNet architecture, as well as a baseline model for reference, were evaluated based on the average 3D localization errors for the AC and PC points across 311 MRI volumes. Our DeepNavNet model significantly outperformed a baseline and achieved a mean 3D localization error of 0.79 ± 0.33 mm and 0.78 ± 0.33 mm between the ground truth and the detected AC and PC points, respectively. In conclusion, the DeepNavNet model pipeline provides submillimeter accuracy for localizing AC and PC anatomical landmarks in MRI volumes, enabling improved surgical efficiency and accuracy.
PubMed: 34220429
DOI: 10.3389/fnins.2021.670287 -
Plastic and Reconstructive Surgery.... Jul 2021From early on in the development of plastic surgery, it was quickly realized that utilizing locally adjacent tissue, or "matching like with like," yielded superior... (Review)
Review
From early on in the development of plastic surgery, it was quickly realized that utilizing locally adjacent tissue, or "matching like with like," yielded superior aesthetic reconstructions to those in which the tissue was derived from a distant location. In many cases, the use of a local perforator flap is a simpler procedure with less patient morbidity and a quicker recovery from surgery. The difficulty with local perforator flaps has been locating the supplying perforators, ensuring that the flap has a robust and reliable blood supply, and that sufficient tissue is able to be transferred. The recent reappraisal of our understanding of the blood supply of the integument has allowed, for the first time, the capacity to accurately and inexpensively, without the need for "high tech equipment," locate perforators, as they emerge from the deep fascia into the overlying integument, and through a better understanding of the interconnecting anastomotic vessels between perforators reliably predict how much tissue can be safely raised on a single perforator, before surgery. Further, through the use of strategic "delay," it is possible to manipulate the interconnecting vessels between the selected perforator and its surrounding neighbors to design a flap of tissue of any dimension, composed of whatever tissue we require, and safely transfer that tissue locally, or if required, distantly, as a free flap. This article will highlight these advances, explain their relevance in raising reliable local perforator flaps, and will, where possible, call attention to any pearls and pitfalls, and how to avoid complications.
PubMed: 34422514
DOI: 10.1097/GOX.0000000000003673 -
AMIA Joint Summits on Translational... 2022Air ambulances can provide more rapid access to medical care than ground ambulances for rural, underserved, and hard to reach populations. However, the existing...
Air ambulances can provide more rapid access to medical care than ground ambulances for rural, underserved, and hard to reach populations. However, the existing allocation of ambulance bases across metropolitan and rural areas is driven primarily by individual operator decisions rather than a health outcomes-based approach. This paper describes a framework for optimizing air ambulance services delivery based on healthcare demand and locational constraints to other modes of transportation. In particular, the paper highlights the need for combining data and how data can be used to identify locations where air ambulance services could be located based on impact. We utilize an information systems approach, applying linear programing models to identify the optimal base locations at the state and regional level. Two data driven use cases for the state of Virginia and New England demonstrate the application of our approach and underscore the importance of data interoperability in health transportation planning.
PubMed: 35854752
DOI: No ID Found -
Biological Reviews of the Cambridge... May 2017Locating suitable feeding or oviposition sites is essential for insect survival. Understanding how insects achieve this is crucial, not only for understanding the... (Review)
Review
Locating suitable feeding or oviposition sites is essential for insect survival. Understanding how insects achieve this is crucial, not only for understanding the ecology and evolution of insect-host interactions, but also for the development of sustainable pest-control strategies that exploit insects' host-seeking behaviours. Volatile chemical cues are used by foraging insects to locate and recognise potential hosts but in nature these resources usually are patchily distributed, making chance encounters with host odour plumes rare over distances greater than tens of metres. The majority of studies on insect host-seeking have focussed on short-range orientation to easily detectable cues and it is only recently that we have begun to understand how insects overcome this challenge. Recent advances show that insects from a wide range of feeding guilds make use of 'habitat cues', volatile chemical cues released over a relatively large area that indicate a locale where more specific host cues are most likely to be found. Habitat cues differ from host cues in that they tend to be released in larger quantities, are more easily detectable over longer distances, and may lack specificity, yet provide an effective way for insects to maximise their chances of subsequently encountering specific host cues. This review brings together recent advances in this area, discussing key examples and similarities in strategies used by haematophagous insects, soil-dwelling insects and insects that forage around plants. We also propose and provide evidence for a new theory that general and non-host plant volatiles can be used by foraging herbivores to locate patches of vegetation at a distance in the absence of more specific host cues, explaining some of the many discrepancies between laboratory and field trials that attempt to make use of plant-derived repellents for controlling insect pests.
Topics: Animals; Ecosystem; Herbivory; Insecta; Odorants; Plants
PubMed: 27145528
DOI: 10.1111/brv.12281 -
PloS One 2024With more and more demand from devices to use wireless communication networks, there has been an increased interest in resource sharing among operators, to give a better...
With more and more demand from devices to use wireless communication networks, there has been an increased interest in resource sharing among operators, to give a better link quality. However, in the analysis of the benefits of resource sharing among these operators, the important factor of co-location is often overlooked. Indeed, often in wireless communication networks, different operators co-locate: they place their base stations at the same locations due to cost efficiency. We therefore use stochastic geometry to investigate the effect of co-location on the benefits of resource sharing. We develop an intricate relation between the co-location factor and the optimal radius to operate the network, which shows that indeed co-location is an important factor to take into account. We also investigate the limiting behavior of the expected gains of sharing, and find that for unequal operators, sharing may not always be beneficial when taking co-location into account.
Topics: Efficiency; Wireless Technology
PubMed: 38394126
DOI: 10.1371/journal.pone.0299396 -
BMC Medical Informatics and Decision... Jun 2022In a sudden cardiac arrest, starting CPR and applying an AED immediately are the two highest resuscitation priorities. Many existing mobile applications have been...
BACKGROUND
In a sudden cardiac arrest, starting CPR and applying an AED immediately are the two highest resuscitation priorities. Many existing mobile applications have been developed to assist users in locating a nearby AED. However, these applications do not provide indoor navigation to the AED location. The time required to locate an AED inside a building due to a lack of indoor navigation systems will reduce the patient's chance of survival. The existing indoor navigation solutions either require special hardware, a large dataset or a significant amount of initial work. These requirements make these systems not viable for implementation on a large-scale.
METHODS
The proposed system collects Wi-Fi information from the existing devices and the path's magnetic information using a smartphone to guide the user from a starting point to an AED. The information collected is processed using four techniques: turn detection method, Magnetic data pattern matching method, Wi-Fi fingerprinting method and Closest Wi-Fi location method to estimate user location. The user location estimations from all four techniques are further processed to determine the user's location on the path, which is then used to guide the user to the AED location.
RESULTS
The four techniques used in the proposed system Turn detection, Magnetic data pattern matching, Closest Wi-Fi location and Wi-Fi fingerprinting can individually achieve the accuracy of 80% with the error distance ± 9.4 m, ± 2.4 m, ± 4.6 m, and ± 4.6 m respectively. These four techniques, applied individually, may not always provide stable results. Combining these techniques results in a robust system with an overall accuracy of 80% with an error distance of ± 2.74 m. In comparison, the proposed system's accuracy is higher than the existing systems that use Wi-Fi and magnetic data.
CONCLUSION
This research proposes a novel approach that requires no special hardware, large scale data or significant initial work to provide indoor navigation. The proposed system AEDNav can achieve an accuracy similar to the existing indoor navigation systems. Implementing this indoor navigation system could reduce the time to locate an AED and ultimately increase patient survival during sudden cardiac arrest.
Topics: Death, Sudden, Cardiac; Defibrillators; Heart Arrest; Humans; Mobile Applications; Smartphone
PubMed: 35725395
DOI: 10.1186/s12911-022-01886-7