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Revista Chilena de Pediatria 2017Health supervision is a privileged opportunity to walk along with the new families during their transition to parenthood. This period is challenging for both mother and... (Review)
Review
Health supervision is a privileged opportunity to walk along with the new families during their transition to parenthood. This period is challenging for both mother and father, and there is the potential danger that demand surpasses the existing resources of the family. This imbalance may lead to mothers and fathers to develop depressive symptomatology. Postpartum depression may affect one to two out of ten men, and maternal depression is a major risk factor for developing it. The postpartum depression in the father impact all the family members, being the child development, the bonding, and the child´s mental health which can be disturb at a short, medium and long term. Therefore, it seems to be relevant to think about screening for post partum depression not only in mothers but also fathers, and give a first step to broaden the gaze from the dyad to the triad. The health supervision is a unique opportunity to be able to carry out this screening; however, the validation of a postpartum screening test for Chilean fathers is a pending task.
Topics: Depression, Postpartum; Depressive Disorder; Father-Child Relations; Fathers; Female; Humans; Infant; Infant, Newborn; Male; Object Attachment
PubMed: 29546941
DOI: 10.4067/S0370-41062017000500002 -
Anaesthesia Apr 2021Perinatal mental illness is common, affecting up to 20% of women, but remains under-recognised and under-diagnosed. It may have adverse effects on pregnancy and neonatal... (Review)
Review
Perinatal mental illness is common, affecting up to 20% of women, but remains under-recognised and under-diagnosed. It may have adverse effects on pregnancy and neonatal outcomes, and mental disorder remains one of the leading causes of maternal death in the UK. Women with mental ill health face difficult decisions in balancing risks and benefits of treatment. Stigma related to mental disorder may lead to non-engagement with maternity care. Some disorders bring specific challenges for anaesthetists working in maternity settings and it is vital that anaesthetists have knowledge of these disorders so they may offer care which is sensitive and appropriate.
Topics: Antidepressive Agents; Anxiety Disorders; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Mental Disorders; Postpartum Period; Pregnancy; Pregnancy Complications
PubMed: 33682099
DOI: 10.1111/anae.15424 -
Canadian Journal of Psychiatry. Revue... Mar 2014To examine the effects of classification on treatment in major depressive disorder (MDD). (Review)
Review
OBJECTIVE
To examine the effects of classification on treatment in major depressive disorder (MDD).
METHOD
This is a narrative review.
RESULTS
MDD is a highly heterogeneous category, leading to problems in classification and in specificity of treatment. Current models classify all depressions within a single category. However, the construct of MDD obscures important differences between severe disorders that require pharmacotherapy, and mild-to-moderate disorders that can respond to psychotherapy or remit spontaneously. Patients with mild-to-moderate MDD are being treated with routine or overly aggressive pharmacotherapy.
CONCLUSIONS
The current classification fails to address the heterogeneity of depression, leading to mistreatment.
Topics: Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Humans; Inappropriate Prescribing; Psychotherapy; Treatment Outcome
PubMed: 24881163
DOI: 10.1177/070674371405900306 -
Psychological Medicine Nov 2010The goal of the present study was to analyze associations between depression and mortality of cancer patients and to test whether these associations would vary by study... (Meta-Analysis)
Meta-Analysis
BACKGROUND
The goal of the present study was to analyze associations between depression and mortality of cancer patients and to test whether these associations would vary by study characteristics.
METHOD
Meta-analysis was used for integrating the results of 105 samples derived from 76 prospective studies.
RESULTS
Depression diagnosis and higher levels of depressive symptoms predicted elevated mortality. This was true in studies that assessed depression before cancer diagnosis as well as in studies that assessed depression following cancer diagnosis. Associations between depression and mortality persisted after controlling for confounding medical variables. The depression-mortality association was weaker in studies that had longer intervals between assessments of depression and mortality, in younger samples and in studies that used the Beck Depression Inventory as compared with other depression scales.
CONCLUSIONS
Screening for depression should be routinely conducted in the cancer treatment setting. Referrals to mental health specialists should be considered. Research is needed on whether the treatment of depression could, beyond enhancing quality of life, extend survival of depressed cancer patients.
Topics: Age Factors; Depressive Disorder; Female; Humans; Male; Middle Aged; Neoplasms; Psychiatric Status Rating Scales; Sex Factors; Survival Analysis
PubMed: 20085667
DOI: 10.1017/S0033291709992285 -
Current Neuropharmacology 2021Multiple studies on the pathomechanisms of depressive disorder and antidepressants have been reported. However, literature involving scientometric analysis of depressive...
Multiple studies on the pathomechanisms of depressive disorder and antidepressants have been reported. However, literature involving scientometric analysis of depressive disorder is sparse. Here, we use scientometric analysis and a historical review to highlight recent research on depression. We use the former to examine research on depressive disorders from 1998 to 2018. The latter is used to identify the most frequent keywords in keyword analysis, as well as explore hotspots and depression trends. Scientometric analysis uncovered field distribution, knowledge structure, research topic evolution, and topics emergence as main explorations in depressive disorder. Induction factor, comorbidity, pathogenesis, therapy and animal models of depression help illustrate occurrence, development and treatment of depressive disorder. Scientometric analysis found 231,270 research papers on depression, a 4-fold increase over the last 20 years. These findings offer a vigorous roadmap for further studies in this field.
Topics: Animals; Antidepressive Agents; Bibliometrics; Depressive Disorder; Publications
PubMed: 32888272
DOI: 10.2174/1570159X18666200905151333 -
Acta Psychiatrica Scandinavica May 2018To provide an update on the evidence base for the nature of the relationship between negative symptoms and depressive features in people with schizophrenia, and propose...
OBJECTIVE
To provide an update on the evidence base for the nature of the relationship between negative symptoms and depressive features in people with schizophrenia, and propose new models that reflect their complex relationship.
METHOD
A systematic review following PRISMA guidelines. A total of 2210 articles were identified from EMBASE, PsychInfo and MEDLINE, and further two articles were hand-searched from references. Twenty-seven met inclusion criteria and were included in the review.
RESULTS
In schizophrenia, primary evidence suggests symptoms of low mood, suicidal ideation and pessimism have more specificity for depression whereas alogia and blunted affect may have more specificity as negative symptoms. Anhedonia, anergia and avolition may be common to both.
CONCLUSION
It may be possible to further distinguish depressive features from negative symptoms in schizophrenia when detailed phenomenology is considered. However, in a proposed dimensional model, these two domains continue to share certain phenomena, highlighting their close relationship.
Topics: Comorbidity; Depressive Disorder; Humans; Schizophrenia
PubMed: 29532909
DOI: 10.1111/acps.12873 -
Journal of the American Academy of... Mar 2019Depression is the most prominent mental health disorder among youth and has a profound impact with respect to morbidity and mortality if not addressed. The Treatment for... (Randomized Controlled Trial)
Randomized Controlled Trial
OBJECTIVE
Depression is the most prominent mental health disorder among youth and has a profound impact with respect to morbidity and mortality if not addressed. The Treatment for Adolescent Depression Study (TADS) is one of the largest randomized controlled trials that compared the effectiveness of four treatments: cognitive-behavioral therapy (CBT); fluoxetine (FLX); combined cognitive-behavioral and fluoxetine treatment (COMB); and placebo (PBO). However, meaningful heterogeneous treatment courses are masked by these group mean comparisons of treatment impact. The present study sought to characterize the acute phase symptom trajectories of the depressed teens enrolled in TADS and to explore predictors of these trajectories, including TADS treatment condition.
METHOD
The TADS sample of 439 adolescent participants diagnosed with major depressive disorder was subjected to growth mixture modeling (GMM) to evaluate subgroups of adolescents with unique trajectories of depression symptom change.
RESULTS
Growth mixture modeling revealed three unique classes of adolescents: (1) a high-severity class with early significant improvement; (2) a high-severity class with limited symptom change; and (3) a moderate severity class with late significant improvement. Baseline predictors of class membership included treatment condition, sex, age, stage of change, depression severity, number of comorbid disorders, hopelessness, melancholia, suicidality, and cognitive distortions.
CONCLUSION
Results of this study may have implications for the selection of which treatment to use for which depressed adolescent.
CLINICAL TRIAL REGISTRATION INFORMATION
Treatment for Adolescents With Depression Study (TADS); https://clinicaltrials.gov/; NCT00006286.
Topics: Adolescent; Cognitive Behavioral Therapy; Combined Modality Therapy; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; Fluoxetine; Humans; Male; Quality of Life; Remission Induction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; United States
PubMed: 30768414
DOI: 10.1016/j.jaac.2018.07.908 -
The Psychiatric Clinics of North America Mar 2018This article covers current research on the relationship between depression and cognitive impairment in older adults. First, it approaches the clinical assessment of... (Review)
Review
This article covers current research on the relationship between depression and cognitive impairment in older adults. First, it approaches the clinical assessment of late-life depression and comorbid cognitive impairment. Cognitive risk factors for suicide are discussed. Research is then provided on neuropsychological changes associated with depression, discussing subjective cognitive impairment, mild cognitive impairment, and dementia profiles. Additionally, literature regarding neuroimaging and biomarker findings in depressed older adults is presented. Finally, therapeutic models for treatment of late-life depression are also discussed, including psychotherapy models, holistic treatments, pharmacologic approaches, and brain-stimulation therapies.
Topics: Aged; Aging; Comorbidity; Depressive Disorder; Humans; Neurocognitive Disorders; Psychotherapy
PubMed: 29412840
DOI: 10.1016/j.psc.2017.10.009 -
Lakartidningen Jan 2019
Topics: Antidepressive Agents; Cognitive Behavioral Therapy; Combined Modality Therapy; Depressive Disorder; Humans; Secondary Prevention
PubMed: 30644995
DOI: No ID Found -
Tidsskrift For Den Norske Laegeforening... Mar 2020
Topics: Depressive Disorder; Grief; Humans
PubMed: 32238967
DOI: 10.4045/tidsskr.19.0504