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Journal of Applied Oral Science :... 2018The objective of this study was to compare selective physical-mechanical properties, antibacterial effects and cytotoxicity of seven temporary restorative materials...
The objective of this study was to compare selective physical-mechanical properties, antibacterial effects and cytotoxicity of seven temporary restorative materials (TRM): five resin-based materials [Bioplic (B), Fill Magic Tempo (FM), Fermit inlay (F), Luxatemp LC (L) and Revotek LC (R)], and zinc oxide-eugenol cement (IRM) and glass ionomer cement (GIC) as the controls. Material and methods The physical-mechanical properties were evaluated by determining microleakage (ML), ultimate tensile strength (UTS) and Shore D hardness (SDH). In addition, the polymerization rate (Pr-1), depth of cure (DC), water sorption and solubility (WS/SL) were evaluated. The antimicrobial effects of the materials were assessed by biofilm accumulation of Streptococcus mutans (BT) and the direct contact test (DCT) by exposure to Enterococcus faecalis for 1 and 24 h, and cytotoxicity by MTT assay. The data were analyzed by ANOVA or Kruskall-Wallis tests, and a complementary post-hoc method (p<0.05). Results Group B, followed by FM and GIC had significantly lower percentages of microleakage in comparison with the other groups; Groups FM and L showed the highest WS, while Groups R and FM showed the significantly lowest SL values (p<0.05). Group R showed the statistically highest UTS mean and the lowest DC mean among all groups. Group F showed the lowest S. mutans biofilm accumulation (p=0.023). Only the Group L showed continued effect against E. faecalis after 1 h and 24 h in DCT. The L showed statistically lower viability cell when compared to the other groups. Conclusions These findings suggest the antibacterial effect of the temporary materials Fill Magic and Bioplic against S. mutans, while Luxatemp showed in vitro inhibition of S. mutans biofilm accumulation and E. faecalis growth. Regarding the cell viability test, Luxatemp was the most cytotoxic and Fill Magic was shown to be the least cytotoxic.
Topics: Animals; Anti-Bacterial Agents; Bisphenol A-Glycidyl Methacrylate; Cattle; Cell Survival; Composite Resins; Dental Leakage; Dental Restoration, Temporary; Enterococcus faecalis; Fibroblasts; Glass Ionomer Cements; Hardness Tests; Materials Testing; Methylmethacrylates; Mice; Polymethacrylic Acids; Reproducibility of Results; Root Canal Filling Materials; Solubility; Streptococcus mutans; Tensile Strength; Time Factors; Zinc Oxide-Eugenol Cement
PubMed: 30133673
DOI: 10.1590/1678-7757-2017-0562 -
Journal of Prosthodontic Research Jul 2023We aimed to evaluate the effectiveness of photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC) in inhibiting Candida albicans biofilm formation on polymethyl...
PURPOSE
We aimed to evaluate the effectiveness of photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC) in inhibiting Candida albicans biofilm formation on polymethyl methacrylate (PMMA) and assess its mechanism and need for re-application by evaluating its interaction with salivary mucin and durability during temperature changes.
METHODS
PMMA discs were used as specimens. The MPC coating was applied using the spray and cure technique for the treatment groups, whereas no coating was applied to the control. The MPC treatment (MT) groups were further differentiated based on the number of thermal cycles involved (0, 1000, 2500, and 5000). The optical density was measured to assess mucin adsorption (MA). Contact angle (CA) was calculated to evaluate surface hydrophilicity. The presence of MPC components on the PMMA surface was assessed using X-ray photoelectron spectroscopy (XPS). C. albicans biofilms were evaluated qualitatively (scanning electron microscope images) and quantitatively (colony-forming units (CFUs)). Statistical analysis was conducted using two-way analysis of variance and Tukey's multiple comparison test.
RESULTS
MA rate and CA increased significantly in the MT groups, which exhibited significantly fewer CFUs and thinner biofilms than those of the control group. Based on the XPS, MA, and CFU evaluations, the durability and efficacy of the MPC coating were considered stable up to 2500 thermal cycles. Additionally, a significant interaction was observed between mucin concentration and MPC efficacy.
CONCLUSIONS
The photoreactive MPC coating, which was resistant to temperature changes for approximately 3 months, effectively prevented C. albicans biofilm formation by modifying surface hydrophilicity and increasing mucin adsorption.
Topics: Candida albicans; Acrylic Resins; Polymers; Polymethyl Methacrylate; Surface Properties; Biofilms; Mucins
PubMed: 36288959
DOI: 10.2186/jpr.JPR_D_22_00102 -
International Archives of Occupational... Jan 2019Exposures of nail salon technicians have received attention due to the potentially toxic materials used in nail products, which include volatile organic compounds (VOCs)...
PURPOSE
Exposures of nail salon technicians have received attention due to the potentially toxic materials used in nail products, which include volatile organic compounds (VOCs) such as formaldehyde and methyl methacrylate (MMA). This study characterized area and personal concentrations and other indoor air parameters in 17 nail salons in fall and winter seasons in three areas of Michigan.
METHODS
VOC samples were analyzed using thermal desorption, gas chromatography and mass spectroscopy, and the VOC composition of 35 nail products (e.g., polish, top coat, base coat) was measured using headspace sampling. Ventilation rates were derived using CO concentrations, occupancy and building information, and VOC sources were apportioned by a novel application of chemical mass balance models.
RESULTS
We detected ethyl acetate, propyl acetate, butyl acetate, MMA, n-heptane and toluene in most salons, and benzene, D-limonene, formaldehyde, and ethyl methacrylate in some salons. While MMA was not measured in the consumer and professional products, and the use of pure MMA in salons has been not been permitted since the 1970s, MMA was found in air at concentrations from 100 to 36,000 µg/m in 15 of 17 salons; thus its use appears to be commonplace in the industry. Personal measurements, representing exposures to workers and clients, were about twice those of the area measurements for many VOCs.
CONCLUSION
This study identifies the products responsible for emissions, shows the widespread presence of MMA, and documents low ventilation rates in some salons. It also demonstrates that "informal" short-term sampling approaches can evaluate chemical exposures in nail salons, providing measurements that can be used to protect a potentially susceptible and vulnerable population. Additional controls, including restrictions on the VOC compositions and improved ventilation, can reduce exposures to salon workers and clients.
Topics: Air Pollutants, Occupational; Air Pollution, Indoor; Carbon Dioxide; Cosmetics; Formaldehyde; Humans; Methylmethacrylates; Michigan; Occupational Exposure; Pilot Projects; Seasons; Ventilation; Volatile Organic Compounds
PubMed: 30276513
DOI: 10.1007/s00420-018-1353-0 -
Cleveland Clinic Journal of Medicine Feb 2003New drugs to treat osteoporosis, along with two new minimally invasive surgical procedures, are important options for preventing vertebral compression fractures and... (Review)
Review
New drugs to treat osteoporosis, along with two new minimally invasive surgical procedures, are important options for preventing vertebral compression fractures and treating severe back pain and disability. However, the mainstay treatments remain cautious use of analgesics, limited bed rest, and physical rehabilitation.
Topics: Bone Cements; Braces; Humans; Methylmethacrylate; Osteoporosis; Spinal Fractures
PubMed: 12636346
DOI: 10.3949/ccjm.70.2.147 -
International Orthopaedics 1999
Review
Topics: Arthroplasty, Replacement, Hip; Bone Cements; Burns, Chemical; Femoral Nerve; Humans; Intraoperative Complications; Jurisprudence; Methylmethacrylate; Mononeuropathies; Nerve Compression Syndromes; Obturator Nerve; Paralysis; Peripheral Nervous System Diseases; Peroneal Nerve; Reoperation; Risk Assessment; Sciatic Nerve; Wounds, Penetrating
PubMed: 10486021
DOI: 10.1007/s002640050329 -
Translational Vision Science &... Dec 2020To evaluate titanium (Ti) sputtering of the poly(methyl methacrylate) (PMMA) stem of the Boston Keratoprosthesis (BK) as a method to enhance interfacial adhesion between...
PURPOSE
To evaluate titanium (Ti) sputtering of the poly(methyl methacrylate) (PMMA) stem of the Boston Keratoprosthesis (BK) as a method to enhance interfacial adhesion between the PMMA and the recipient corneal tissue.
METHODS
PMMA specimens were plasma treated with Ar/O and coated with Ti using a DC magnetron sputtering instrument. The topography and hydrophilicity of the surfaces were characterized using atomic force microscopy and a water contact angle instrument, respectively. Scratch hardness and adhesion of the Ti film were measured using a mechanical tester. Biocompatibility assessments were performed using cultured human corneal fibroblasts and whole blood ex vivo. The optical quality of the Ti sputtered BK was evaluated using a custom-made optical bench.
RESULTS
By contact angle studies, the Ti coating improved PMMA hydrophilicity to match that of medical-grade Ti (Ti-6Al-4V-ELI). Ti sputtering of contact surfaces resulted in a plate-like morphology with increased surface roughness, without impacting the transparency of the BK optical component. Scratch testing indicated that the mechanical behavior of the Ti coating was similar to that of casted Ti, and the coating was stable in pull-off adhesion testing. Sputtered Ti film was highly biocompatible based on tests of cell viability, adhesion, proliferation, differentiation, collagen deposition, and keratocan expression, the properties of which exceeded those of uncoated PMMA and did not induce increased complement activation.
CONCLUSIONS
Titanium coating of the BK stem generated a mechanically and biologically favorable interface, which may help to enhance corneal stromal adhesion and biocompatibility.
TRANSLATIONAL RELEVANCE
Improving the biocompatibility of the BK PMMA stem may improve long-term outcomes of implantation.
Topics: Cornea; Humans; Polymethyl Methacrylate; Prostheses and Implants; Surface Properties; Titanium
PubMed: 33442495
DOI: 10.1167/tvst.9.13.41 -
International Journal of Molecular... Apr 2010Herein, we report the synthesis of monomethacryloyl sucrose esters, and their successful free radical homo- and co-polymerisation with styrene, methylmethacrylate,...
Herein, we report the synthesis of monomethacryloyl sucrose esters, and their successful free radical homo- and co-polymerisation with styrene, methylmethacrylate, α-and β-pinene. The chemical, physical, structural and surface chemical properties of these polymers, containing a hydrophobic olefin backbone and hydrophilic sugar moieties as side chains, have been investigated. Biodegradation tests of the copolymer samples by a microbial fungal culture (Aspergillus niger) method showed good biodegradability. The chemical structure and surface chemistry of the synthesized homo- and co-polymers demonstrate their potential technological relevance as amphiphilic and biodegradable polymers.
Topics: Aspergillus niger; Bicyclic Monoterpenes; Biodegradation, Environmental; Bridged Bicyclo Compounds; Esters; Free Radicals; Hydrophobic and Hydrophilic Interactions; Methylmethacrylate; Monoterpenes; Polymerization; Polymers; Styrene; Sucrose
PubMed: 20480042
DOI: 10.3390/ijms11041792 -
British Medical Journal Dec 1972
Topics: Aged; Bone Cements; Electrocardiography; Humans; Hypotension; Methylmethacrylates; Time Factors
PubMed: 4645905
DOI: 10.1136/bmj.4.5841.667-a -
British Medical Journal Jan 1973
Topics: Arthroplasty; Bone Cements; Femur; Humans; Hypotension; Hypotension, Controlled; Methods; Methylmethacrylates; Postoperative Complications
PubMed: 4686572
DOI: 10.1136/bmj.1.5847.236-b -
Scientific Reports Mar 2023This article presents that acrylate copolymers are the potential candidate against the adsorption of bovine serum albumin (BSA). A series of copolymers poly(methyl...
This article presents that acrylate copolymers are the potential candidate against the adsorption of bovine serum albumin (BSA). A series of copolymers poly(methyl methacrylate) (pMMA), poly(3-sulfopropyl methacrylate-co-methyl methacrylate) p(SPMA-co-MMA), and poly(dimethylaminoethyl methacrylate-co-methyl methacrylate) p(DMAEMA-co-MMA) were synthesized via free radical polymerization. These amphiphilic copolymers are thermally stable with a glass transition temperature (Tg) 50-120 °C and observed the impact of surface charge on amphiphilic copolymers to control interactions with the bovine serum albumin (BSA). These copolymers pMD1 and pMS1 have surface charges, - 56.6 and - 72.6 mV at pH 7.4 in PBS buffer solution that controls the adsorption capacity of bovine serum albumin (BSA) on polymers surface. Atomic force microscopy (AFM) analysis showed minimum roughness of 0.324 nm and 0.474 nm for pMS1 and pMD1. Kinetic studies for BSA adsorption on these amphiphilic copolymers showed the best fitting of the pseudo-first-order model that showed physisorption and attained at 25 °C and pH 7.4 within 24 h.
Topics: Serum Albumin, Bovine; Kinetics; Polymers; Polymethyl Methacrylate; Acrylates; Methacrylates
PubMed: 36941313
DOI: 10.1038/s41598-023-27515-5