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Journal of Nuclear Medicine : Official... Nov 2013PET and SPECT can play an important role in the evaluation of various epileptic syndromes, particularly those with unknown causes, by revealing various underlying... (Review)
Review
PET and SPECT can play an important role in the evaluation of various epileptic syndromes, particularly those with unknown causes, by revealing various underlying abnormalities that may not be fully appreciated from MR imaging studies. In some cases, PET and SPECT provide crucial data that guide surgical resections of the epileptogenic zone for medically refractory epilepsy. In other cases, these neuroimaging modalities preclude a surgical option and can guide genetic studies. Longitudinal PET and SPECT studies may increase our understanding of the etiopathogenesis of epilepsy syndromes and provide a clearer picture of the natural history of neurologic progression.
Topics: Epilepsy; Humans; Positron-Emission Tomography; Radionuclide Imaging; Tomography, Emission-Computed, Single-Photon
PubMed: 24029652
DOI: 10.2967/jnumed.113.129593 -
PET Clinics Jul 2018Recent advances in nuclear medicine instrumentation have led to the emergence of improved molecular imaging techniques to image breast cancer: dedicated gamma cameras... (Review)
Review
Recent advances in nuclear medicine instrumentation have led to the emergence of improved molecular imaging techniques to image breast cancer: dedicated gamma cameras using γ-emitting Tc-sestamibi and breast-specific PET cameras using F-fluorodeoxyglucose. This article focuses on the current role of such approaches in the clinical setting including diagnosis, assessing local extent of disease, monitoring response to therapy, and, for gamma camera imaging, possible supplemental screening in women with dense breasts. Barriers to clinical adoption and technologies and radiotracers under development are also discussed.
Topics: Breast; Breast Neoplasms; Female; Gamma Cameras; Humans; Positron-Emission Tomography; Radionuclide Imaging; Reproducibility of Results
PubMed: 30100076
DOI: 10.1016/j.cpet.2018.02.008 -
Reumatologia Clinica 2017
Topics: Adult; Camurati-Engelmann Syndrome; Female; Humans; Radionuclide Imaging
PubMed: 26830437
DOI: 10.1016/j.reuma.2015.12.004 -
European Heart Journal. Cardiovascular... Oct 2017This joint position paper illustrates the role and the correct use of echocardiography, radionuclide imaging with 18F-fluorodeoxyglucose positron emission tomography,... (Review)
Review
A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology.
This joint position paper illustrates the role and the correct use of echocardiography, radionuclide imaging with 18F-fluorodeoxyglucose positron emission tomography, radionuclide myocardial perfusion imaging and cardiovascular magnetic resonance imaging for the evaluation and management of patients with known or suspected cardiac sarcoidosis. This position paper will aid in standardizing imaging for cardiac sarcoidosis and may facilitate clinical trials and pooling of multi-centre data on cardiac sarcoidosis. Proposed flow charts for the work up and management of cardiac sarcoidosis are included.
Topics: Cardiac Imaging Techniques; Cardiology; Cardiomyopathies; Europe; Female; Humans; Magnetic Resonance Imaging; Male; Multimodal Imaging; Myocardial Perfusion Imaging; Nuclear Medicine; Positron Emission Tomography Computed Tomography; Practice Guidelines as Topic; Radionuclide Imaging; Sarcoidosis; Societies, Medical; United States
PubMed: 28984894
DOI: 10.1093/ehjci/jex146 -
Journal of Nuclear Medicine Technology Jun 2019Dialysis is an artificial process to remove waste products and excess water from the body in patients with kidney failure. Two main types of dialysis are available.... (Review)
Review
Dialysis is an artificial process to remove waste products and excess water from the body in patients with kidney failure. Two main types of dialysis are available. Hemodialysis, which uses an artificial filtration apparatus, is usually done at specialized centers but can be done in a patient's home. Peritoneal dialysis functions by placing dialysis fluid, also called dialysate, into the peritoneal cavity, allowing for solute to be removed from the peritoneal capillaries through diffusion across a chemical gradient into the dialysate and removal of water through an osmotic gradient created by hypertonic dextrose. Peritoneal dialysis can be either automated, which is done with the help of a machine called a cycler, or continuous ambulatory, which is a process involving multiple exchanges a day and is performed using only gravity to infuse and drain the solution from the peritoneal cavity. For many reasons, the number of people using home dialysis has recently started to rise, with the largest increase in the United States occurring after the implementation of the prospective bundled payment system for end-stage renal disease. With the increased use of home dialysis, potential complications will increase as well. It is imperative that our health-care system be poised not only to increase the number of home dialysis patients but also to diagnose and manage any complications. Nuclear imaging is a commonly available modality to detect various complications related to peritoneal dialysis. In this review article, we discuss the role of peritoneal scintigraphy in detecting some noninfectious peritoneal dialysis complications, with emphasis on scintigraphy technique; imaging time points; the role of planar, SPECT, and SPECT/CT imaging; and the clinical indications, with illustrative case examples.
Topics: Humans; Infections; Peritoneal Dialysis; Radionuclide Imaging; Single Photon Emission Computed Tomography Computed Tomography
PubMed: 30700534
DOI: 10.2967/jnmt.118.223156 -
Paediatric Respiratory Reviews Jun 2012This review will provide an overview of current research into lung imaging with nanoparticles, with a focus on the use of nanoparticles as molecular imaging agents to... (Review)
Review
This review will provide an overview of current research into lung imaging with nanoparticles, with a focus on the use of nanoparticles as molecular imaging agents to observe pathological processes and to monitor the effectiveness of nanoparticulate drug delivery systems. Various imaging modalities together with their advantages and limitations for lung imaging will be discussed. We will also explore the range of nanoparticles used, as well as active or passive targeting of nanoparticles.
Topics: Child; Humans; Lung; Magnetic Resonance Imaging; Molecular Imaging; Nanoparticles; Nanotechnology; Radionuclide Imaging; Tomography, X-Ray Computed
PubMed: 22475253
DOI: 10.1016/j.prrv.2011.07.001 -
The Quarterly Journal of Nuclear... Mar 2005Nuclear cardiology has historically played an important role in detection of cardiovascular disease as well as risk stratification. With the growth of molecular biology... (Review)
Review
Nuclear cardiology has historically played an important role in detection of cardiovascular disease as well as risk stratification. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted radiotracer based as well as transporter gene imaging strategies are evolving to meet these new needs, but require the development of an interdisciplinary approach which focuses on molecular processes, as well as the pathogenesis and progression of disease. This progress has been made possible with the availability of transgenic animal models along with many technological advances. Future adaptations of the developing experimental procedures and instrumentation will allow for the smooth translation and application to clinical practice. This review is intended as a brief overview on the subject molecular imaging. Basic concepts and historical perspective of molecular imaging will be reviewed first, followed by description of current technology, and concluding with current applications in cardiology. The emphasis will be on the use of both single photon emission computed tomography (SPECT) and positron emission tomography (PET) radiotracers, although other imaging modalities will be also briefly discussed. The specific approaches presented here will include receptor-based and reporter gene imaging of natural and therapeutic angiogenesis.
Topics: Animals; Cardiology; Cardiovascular Diseases; Gene Expression Profiling; Heart; Humans; Molecular Biology; Molecular Probe Techniques; Molecular Probes; Myocardium; Nuclear Medicine; Radionuclide Imaging; Radiopharmaceuticals
PubMed: 15724140
DOI: No ID Found -
Journal of Veterinary Internal Medicine 2007This review describes the advantages and disadvantages of radiography, ultrasonography, and nuclear medicine in the 2 most frequent thyroid pathologies of the dog:... (Review)
Review
This review describes the advantages and disadvantages of radiography, ultrasonography, and nuclear medicine in the 2 most frequent thyroid pathologies of the dog: acquired primary hypothyroidism and thyroid neoplasia. Ultrasonography and scintigraphy remain the 2 most indicated imaging modalities for these thyroid abnormalities. However, as in human medicine, computed tomography and magnetic resonance imaging also have potential indications. This is especially the case in the evaluation of the extent, local invasiveness, and local or distant metastases of thyroid neoplasia. Based on experience with different imaging modalities in people, we suggest future directions in the imaging of the canine thyroid gland.
Topics: Animals; Dog Diseases; Dogs; Magnetic Resonance Imaging; Radiography; Radionuclide Imaging; Thyroid Diseases; Ultrasonography
PubMed: 17708386
DOI: 10.1892/0891-6640(2007)21[673:tiitdc]2.0.co;2 -
Journal of Nuclear Medicine : Official... Aug 2015Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit scintigraphy, if performed in a comprehensive manner including both... (Review)
Review
Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit scintigraphy, if performed in a comprehensive manner including both quantitative and qualitative analysis of single- and multiple-swallow studies, is clinically useful when expertise in esophageal manometry is not available or not tolerated and when esophageal manometry or barium videofluoroscopy results are equivocal or nondiagnostic. GE scintigraphy has undergone much-needed standardization. Both solid and liquid GE studies play an important role in assessing patients with upper gastrointestinal symptoms. Because measurement of simple total GE is often not sufficient to explain patient symptoms, there is a need to expand the analysis of GE scintigraphy to include the separate roles of the fundus and antrum and to include the complex interactions the stomach has with other organ systems.
Topics: Esophagus; Fluoroscopy; Gamma Cameras; Gastric Emptying; Gastroenterology; Gastrointestinal Motility; Gastrointestinal Tract; Gastrointestinal Transit; Humans; Positron-Emission Tomography; Radionuclide Imaging; Tomography, Emission-Computed, Single-Photon; Video Recording
PubMed: 26025963
DOI: 10.2967/jnumed.112.114314 -
Journal of Nuclear Medicine Technology Sep 2022
Topics: Humans; Neuroendocrine Tumors; Octreotide; Organometallic Compounds; Positron-Emission Tomography; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Peptide
PubMed: 36215643
DOI: No ID Found