-
JAAD Case Reports Aug 2022
PubMed: 35899147
DOI: 10.1016/j.jdcr.2022.06.020 -
Imaging Science in Dentistry Dec 2019Steatocystoma multiplex is an uncommon benign skin disease, which typically manifests as numerous intradermal cysts that can be scattered anywhere on the body. Although...
Steatocystoma multiplex is an uncommon benign skin disease, which typically manifests as numerous intradermal cysts that can be scattered anywhere on the body. Although usually asymptomatic, it can be significantly disfiguring. One type of steatocystoma multiplex is known to be associated with the autosomal dominant inheritance of a mutation in the gene coding for keratin 17 (). In such cases, it is often concurrent with other developmental abnormalities of the ectoderm-derived tissues, such as the nails, hair, and teeth. To the best of our knowledge, few cases have been reported of steatocystoma multiplex of the oral and maxillofacial region. This report describes a case of steatocystoma multiplex of both sides of the neck and multiple dental anomalies, with a focus on its clinical, radiological, and histopathological characteristics, as well as the possibility that the patient exhibited the familial type of this condition.
PubMed: 31915618
DOI: 10.5624/isd.2019.49.4.317 -
Taehan Yongsang Uihakhoe Chi Mar 2021To evaluate the ultrasonographic characteristics of steatocystomas focusing on the features that aid in differentiating them from epidermal inclusion cysts and lipomas.
PURPOSE
To evaluate the ultrasonographic characteristics of steatocystomas focusing on the features that aid in differentiating them from epidermal inclusion cysts and lipomas.
MATERIALS AND METHODS
The ultrasonographic findings of 14 histologically proven steatocystomas in 10 patients were retrospectively reviewed. The following features were assessed: the layer of involvement, shape, margin, echogenicity, posterior acoustic features, and the presence of a visible wall or intralesional striations. The findings were compared with those of subcutaneous lipomas and epidermal inclusion cysts to identify those findings that aid in the differential diagnosis of steatocystomas.
RESULTS
The majority of steatocystomas appeared as a subcutaneous mass ( = 6, 42.9%) or a mass involving both the dermal and subcutaneous layers ( = 6, 42.9%). Steatocystomas exhibited a well-defined smooth margin ( = 12, 85.7%) and homogeneous echogenicity ( = 9, 64.3%), and showed no specific posterior acoustic features ( = 9, 64.3%). The most important features that differentiated steatocystomas from epidermal inclusion cysts were a homogeneous internal echotexture ( = 0.009) and absent or less prominent posterior acoustic enhancement ( < 0.001). The features that distinguished steatocystomas from lipomas were the margin ( < 0.001), echogenicity ( = 0.034), internal echotexture ( = 0.004), and the absence of intralesional striations ( < 0.001).
CONCLUSION
Steatocystomas appeared as well-defined homogeneous masses with mild or absent posterior acoustic enhancement.
PubMed: 36238747
DOI: 10.3348/jksr.2019.0200 -
Singapore Medical Journal Dec 2012Steatocystoma multiplex (SM) is an uncommon cutaneous disorder characterised by multiple intradermal cysts distributed over the trunk and proximal extremities. This...
Steatocystoma multiplex (SM) is an uncommon cutaneous disorder characterised by multiple intradermal cysts distributed over the trunk and proximal extremities. This condition affects both genders and is often inherited as an autosomal dominant trait, although sporadic cases have been described. This report describes the mammographic and sonographic features of the cysts, which presented as breast lumps, for evaluation. The cysts appeared as numerous well-circumscribed, radiolucent nodules with thin radiodense rims on mammography. On sonography, the cysts could be hypoechoic, isoechoic or demonstrate mixed echoes containing debris-fluid levels, depending on the amount of clear oily liquid and keratinous material. SM can be diagnosed based on a clinical setting of multiple asymptomatic small intradermal nodules over the trunk and proximal extremities, positive family history and imaging findings.
Topics: Breast Diseases; Diagnosis, Differential; Female; Humans; Mammography; Middle Aged; Steatocystoma Multiplex; Ultrasonography, Mammary
PubMed: 23268169
DOI: No ID Found -
Journal of Cutaneous and Aesthetic... Jan 2010Steatocystoma multiplex (SM) is a disorder of the pilosebaceous unit characterized by multiple sebum-containing dermal cysts. Different surgical modalities like...
BACKGROUND
Steatocystoma multiplex (SM) is a disorder of the pilosebaceous unit characterized by multiple sebum-containing dermal cysts. Different surgical modalities like cryosurgery, aspiration, surgical excision, incision with a surgical blade or sharp-tipped cautery followed by expression of cyst contents and forceps-assisted removal of the cyst wall and carbon dioxide laser have been used in the past.
AIMS
To study the efficacy of a modified surgical technique in the treatment of steatocystoma multiplex.
MATERIALS AND METHODS
We have used a simple modified surgical technique using a radiofrequency instrument as the incision tool for the treatment of SM in two patients.
RESULTS
The results were cosmetically excellent with no complications developing during or after the procedure. No recurrences were observed after five and half months of follow-up.
CONCLUSIONS
This is a simple, easy, fast office-based procedure that is associated with minimal blood loss and post inflammatory hypo or hyperpigmentation and scarring are practically absent.
PubMed: 20606990
DOI: 10.4103/0974-2077.63284 -
Acta Dermato-venereologica Jan 2015
Topics: Biopsy; Female; Genetic Predisposition to Disease; Heredity; Humans; Phenotype; Steatocystoma Multiplex; Young Adult
PubMed: 24816583
DOI: 10.2340/00015555-1890 -
Cureus Aug 2022Steatocystoma multiplex is an uncommon disease consisting of multiple cysts erupting over the chest, arms, axilla, and neck. It is of unknown incidence and can occur as...
Steatocystoma multiplex is an uncommon disease consisting of multiple cysts erupting over the chest, arms, axilla, and neck. It is of unknown incidence and can occur as a spontaneous mutation or inherited in an autosomal dominant pattern. A 47-year-old female with a past medical history only significant for multiple skin infections presented for a routine mammogram. Her imaging showed multiple circumscribed oil cysts. When contacted regarding the results, the patient said she has noticed multiple cysts presenting on her inner arms, chest, and trunk, of which one would occasionally exsanguinate oily material. She denies any other associated symptoms and says that she is the only member of her family to have these symptoms. The patient was informed of her diagnosis and requested to follow up with her primary care physician to monitor her symptoms. In summary, steatocystoma multiplex is a rare benign condition that can present similarly to a variety of other pathologies. It is important to note the unique clinical features of steatocystoma multiplex in order to prevent unnecessary and costly workup for patients who have this benign condition.
PubMed: 36106249
DOI: 10.7759/cureus.27756 -
Anais Brasileiros de Dermatologia 2016Steatocystoma multiplex is a rare genetic disorder characterized by the presence of hamartomatous malformations at the junction of the pilosebaceous duct. It consists of...
Steatocystoma multiplex is a rare genetic disorder characterized by the presence of hamartomatous malformations at the junction of the pilosebaceous duct. It consists of encapsulated cystic lesions in the dermis, with adjacent sebaceous gland. When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported. This is the first case of steatocystoma multiplex suppurativa reported in the Brazilian literature. Female patient, 23 years old, with papular and nodular cystic lesions that started in the armpits and groin, later spreading to the trunk, lower limbs, anticubital fossa, face and scalp. The presence of papular-nodular lesions associated with disseminated hidradenitis-like lesions in flexural areas and the histopathological diagnosis of steatocystoma defined the diagnosis of steatocystoma multiplex suppurativa.
Topics: Biopsy; Diagnosis, Differential; Epidermal Cyst; Female; Hidradenitis Suppurativa; Humans; Rare Diseases; Sebaceous Glands; Steatocystoma Multiplex; Suppuration; Young Adult
PubMed: 28300893
DOI: 10.1590/abd1806-4841.20164539 -
Indian Journal of Dermatology and... 1970
PubMed: 29160259
DOI: No ID Found -
Case Reports in Dermatology Jul 2010Multiple pilosebaceous cysts include the entities of steatocystoma multiplex and eruptive vellus hair cysts (EVHCs). Multiple pilosebaceous cysts are proposed to be one...
Multiple pilosebaceous cysts include the entities of steatocystoma multiplex and eruptive vellus hair cysts (EVHCs). Multiple pilosebaceous cysts are proposed to be one entity originating in the pilosebaceous duct, since steatocystoma multiplex and EVHCs are frequently present concomitantly and are caused by a cystic change in the same pilosebaceous duct. Here, we describe a patient with yellowish papules, 3-8 mm in diameter, on the neck and skin-colored or light-brown papules, 1-3 mm in diameter, on the neck, chest and upper abdomen. The smaller cysts were histopathologically diagnosed as EVHCs. The larger cysts had both features of EVHCs and steatocystoma multiplex. Therefore, a diagnosis of these lesions was made as multiple pilosebaceous cysts. Our case supports the proposition that multiple pilosebaceous cysts are a more appropriate diagnosis than the terms of EVHCs and steatocystoma multiplex.
PubMed: 20689635
DOI: 10.1159/000317019