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Gut Jul 2013The occurrence of strictures as a complication of Crohn's disease is a significant clinical problem. No specific antifibrotic therapies are available. This systematic... (Review)
Review
The occurrence of strictures as a complication of Crohn's disease is a significant clinical problem. No specific antifibrotic therapies are available. This systematic review comprehensively addresses the pathogenesis, epidemiology, prediction, diagnosis and therapy of this disease complication. We also provide specific recommendations for clinical practice and summarise areas that require future investigation.
Topics: Constriction, Pathologic; Crohn Disease; Fibrosis; Humans; Intestines; Risk Factors
PubMed: 23626373
DOI: 10.1136/gutjnl-2012-304353 -
Multimedia Manual of Cardiothoracic... Dec 2022The treatment of benign subglottic stenoses can be challenging. It requires an experienced multidisciplinary team. It is important to define the aetiology, severity and...
The treatment of benign subglottic stenoses can be challenging. It requires an experienced multidisciplinary team. It is important to define the aetiology, severity and number/types of any pretreatments of the stenosis. Short-term symptom relief can be achieved with endoscopic techniques; however, this relief comes at the price of a high likelihood of restenosis, which often is more severe than the original stenosis. Successful long-term treatment of subglottic stenosis can be achieved by surgical resection in most cases. Cricotracheal resection is the established standard technique to treat subglottic stenosis. In patients with advanced disease, it can be extended by a dorsal mucosectomy, a lateral cricoplasty or a partial anterior laryngeal split in order to remove the entire diseased area. In this video tutorial, we describe a modification of cricotracheal resection. In this technique for an extended resection, the cricoid arch is partially preserved. In addition to restoring sufficient airway width, this modification has the advantage that the cricothyroid joint remains intact. Therefore, the reduction in the pitch and volume of the voice associated with the standard resection techniques is avoided.
Topics: Humans; Constriction, Pathologic; Trachea; Tracheal Stenosis; Laryngostenosis; Cricoid Cartilage; Treatment Outcome
PubMed: 36534064
DOI: 10.1510/mmcts.2022.104 -
World Journal of Urology Nov 2022We aimed to provide a thorough comparative review of the available guidelines on the diagnosis, management, and follow-up for patients with posterior urethral stenosis... (Review)
Review
PURPOSE
We aimed to provide a thorough comparative review of the available guidelines on the diagnosis, management, and follow-up for patients with posterior urethral stenosis by the American Urologic Association (2016), Société Internationale d'Urologie (2010), and European Urologic Association (2022).
METHODS
The AUA, SIU, and EAU guidelines were evaluated for recommendations on the diagnosis, evaluation, and treatment of posterior urethral stenosis. We also included the EAU and AUA urologic trauma guidelines for the trauma-related stenosis. The level or strength of recommendations is included in case of disparity between the guidelines.
RESULTS
The three guidelines align considerably in recommendations provided for the diagnosis, management, and follow-up of patients with posterior urethral stenosis. SIU and EAU emphasize the role of repeat endoscopic treatment in guidelines compared to AUA.
CONCLUSION
The preferred method to repair bulbo-membranous stricture/stenosis following radiation therapy remains an area of active interest, focusing on continence preservation. Additionally, there may be a role for advanced endoscopic treatments with or without adjunct therapies to manage even obliterated stenoses.
Topics: Humans; Male; Urethral Stricture; Urethra; Constriction, Pathologic; Urologic Diseases; Urology; Urologic Surgical Procedures, Male
PubMed: 36018366
DOI: 10.1007/s00345-022-04131-y -
International Braz J Urol : Official... 2022
Topics: Constriction, Pathologic; Humans; Urethra; Urethral Stricture
PubMed: 35838506
DOI: 10.1590/S1677-5538.IBJU.2022.0067.1 -
Asian Journal of Surgery Mar 2023
Topics: Humans; Constriction, Pathologic; Laryngostenosis; Airway Obstruction
PubMed: 36117070
DOI: 10.1016/j.asjsur.2022.08.127 -
European Review For Medical and... Nov 2014Data regarding the cerebral atherosclerotic stenosis (CAS) and incidence of stroke are conflicting. The number of stroke patients is more than three times that from... (Review)
Review
OBJECTIVE
Data regarding the cerebral atherosclerotic stenosis (CAS) and incidence of stroke are conflicting. The number of stroke patients is more than three times that from coronary heart disease in China. The main aim of this report is to review the current status of intracranial and extracranial atherosclerotic stenosis including epidemiology, diagnosis, treatment and risk factors in China.
METHODS
Data was identified by searches of MEDLINE (January 1966 to December 2008), China Biological Medicine Database (CBM-disc 1979 to 2008), China National Knowledge Infrastructure (CNKI 1994 to December 2008).
RESULTS
The occurrence of intracranial artery stenosis was more frequent than that of extracranial artery in the Chinese population. TCD, Doppler ultrasound, CTA, MRA and DSA techniques are established to examine intracranial and extracranial atherosclerotic stenosis in China. Evidence-based treatments and CAS are more commonly applied in patients with cerebrovascular stenosis in China. However, the development of carotid endoarterectomy (CEA) is limited in Chinese communities. The risks of cerebral atherosclerotic stenosis include age, hypertension, diabetes mellitus, dyslipidemia, smoking and metabolic syndrome.
CONCLUSIONS
Further studies are needed to focus on the intracranial atherosclerotic stenosis.
Topics: China; Constriction, Pathologic; Endarterectomy, Carotid; Humans; Hypertension; Intracranial Arteriosclerosis; Risk Factors; Stroke; Treatment Outcome; Vascular Surgical Procedures
PubMed: 25491610
DOI: No ID Found -
Ear, Nose, & Throat Journal Mar 2018
Topics: Constriction, Pathologic; Female; Humans; Laryngeal Edema; Laryngoscopy; Middle Aged; Vocal Cords
PubMed: 29554413
DOI: 10.1177/014556131809700310 -
Contrast Media & Molecular Imaging 2022In order to explore the risk factors of intracranial and intracranial arterial stenosis, the distribution of young ischemic stroke sufferers with intracranial and...
In order to explore the risk factors of intracranial and intracranial arterial stenosis, the distribution of young ischemic stroke sufferers with intracranial and intracranial arterial stenosis and the related are analyzed. In this study, a total of 213 young sufferers with ischemic stroke (IS) admitted to our hospital from February 2019 to September 2021 are selected. According to the CT diagnosis of intracranial artery stenosis (AS), 213 patients are divided into two groups, with 86 in the AS Group and 127 in the non-AS Group. To analyze the distribution of intracranial and intracranial AS in young patients with ischemic stroke, 86 patients with AS are examined by carotid B-mode ultrasound. Furthermore, a univariate analysis is performed on the relevant indicators of the sufferers in the cancer (CA) set and the two sets without CA, and then, the indicators with statistically extensive disparity were selected for multivariate logistic regression analysis of the risk factors for CA symptoms. The results show 50% of the sufferers with moderate or severe ischemic CA in young adults and 63.95% of the sufferers with intracranial artery stenosis. It is clearly evident that the main risk factors affecting the occurrence of intracranial and intracranial arteries in young IS are hypertension and long-term smoking, long-term drinking, and hyperlipidemia.
Topics: Arteries; Constriction, Pathologic; Humans; Ischemic Stroke; Risk Factors; Stroke; Young Adult
PubMed: 35845727
DOI: 10.1155/2022/9684158 -
Inflammatory Bowel Diseases Jan 2016Intestinal fibrosis is a common feature of Crohn's disease and may appear as a stricture, stenosis, or intestinal obstruction. Fibrostenosing Crohn's disease leads to a... (Review)
Review
Intestinal fibrosis is a common feature of Crohn's disease and may appear as a stricture, stenosis, or intestinal obstruction. Fibrostenosing Crohn's disease leads to a significantly impaired quality of life in affected patients and constitutes a challenging treatment situation. In the absence of specific medical antifibrotic treatment options, endoscopic or surgical therapy approaches with their potential harmful side effects are frequently used. However, our understanding of mechanisms of fibrogenesis in general and specifically intestinal fibrosis has emerged. Progression of fibrosis in the liver, lung, or skin can be halted or even reversed, and possible treatment targets have been identified. In face of this observation and given the fact that fibrotic alterations in various organs of the human body share distinct core characteristics, this article aims to address whether reversibility of intestinal fibrosis may be conceivable and to highlight promising research avenues and therapies.
Topics: Constriction, Pathologic; Crohn Disease; Disease Progression; Fibrosis; Humans; Intestinal Obstruction; Postoperative Complications; Prognosis; Quality of Life
PubMed: 26588089
DOI: 10.1097/MIB.0000000000000598 -
International Journal of Pediatric... Sep 2022We reported the free hyoid bone reconstruction of the cricoid cartilage to treat LTS in children. This retrospective case series study included LTS children who... (Review)
Review
We reported the free hyoid bone reconstruction of the cricoid cartilage to treat LTS in children. This retrospective case series study included LTS children who underwent hyoid bone separation and T tube implantation. Thirty-four children were included. Twenty-five children were with good outcomes after free hyoid bone reconstruction of the cricoid cartilage. Specifically, the cure rate was 92.8% for the children with mixed stenosis, followed by 63.6% in children with glottis stenosis and 55.6% in children with subglottic stenosis. Free hyoid bone reconstruction of the cricoid cartilage for the management of LTS is feasible, with good outcomes and few complications.
Topics: Child; Constriction, Pathologic; Cricoid Cartilage; Humans; Hyoid Bone; Laryngostenosis; Neck Injuries; Retrospective Studies; Tracheal Stenosis; Treatment Outcome
PubMed: 35797923
DOI: 10.1016/j.ijporl.2022.111227