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Anais Brasileiros de Dermatologia 2014A case of a tinea favosa involving the scalp of a child represented in the painting "Boys climbing a tree" (Muchachos trepando a un árbol), by Francisco Goya y...
A case of a tinea favosa involving the scalp of a child represented in the painting "Boys climbing a tree" (Muchachos trepando a un árbol), by Francisco Goya y Lucientes, with pictorial representation of favic scutula and consequent alopecia.
Topics: Alopecia; History, 18th Century; Medicine in the Arts; Paintings; Tinea Favosa; Trichophyton
PubMed: 25387510
DOI: 10.1590/abd1806-4841.20143262 -
Medical Mycology Case Reports Dec 2012Favus of the scalp or tinea capitis favosa is a chronic dermatophyte infection of the scalp. In almost cases, favus is caused by Trichophyton schoenleinii,...
INTRODUCTION
Favus of the scalp or tinea capitis favosa is a chronic dermatophyte infection of the scalp. In almost cases, favus is caused by Trichophyton schoenleinii, anthropophilic dermatophyte. It is characterized by the presence of scutula and severe alopecia. Besides the classic clinical type of tinea capitis favosa, there are many variant of clinical form which may persist undiagnosed for many years. In this work, we report an atypical form of favus to Trichophyton schoenleinii which was misdiagnosed as tinea amiantacea.
CASE-REPORT
An 11-year old girl came to the outpatient department of dermatology (day 0) with history of tinea amiantacea treated unsuccessfully with keratolytic shampoo (day - 730). She presented a diffuse scaling of the scalp with thick scaly patches and without scutula or alopecia. A diagnosis of tinea favosa by T. schoenleinii was made by mycological examination. She was treated with griseofulvin and ketoconazole in the form of foaming gel for twelve weeks. Despite treatment, clinical evolution was marked by appearance of permanent alopecia patches. The follow-up mycological examination was negative.
CONCLUSION
Because of ultimate evolution of favus into alopecia, we emphasize the importance of mycological examination in case of diffuse scaling.
PubMed: 24432210
DOI: 10.1016/j.mmcr.2012.12.005 -
International Journal of Infectious... Sep 2022
Topics: Humans; Tinea Favosa
PubMed: 35636635
DOI: 10.1016/j.ijid.2022.05.053 -
Actas Dermo-sifiliograficas 2008
Topics: Dermatologic Agents; History, 19th Century; Humans; Male; Manikins; Museums; Ointments; Spain; Thymol; Tinea Favosa
PubMed: 18558061
DOI: 10.1016/s0001-7310(08)74724-0 -
Proceedings of the Royal Society of... Jul 1947
Topics: Tinea Favosa
PubMed: 19993612
DOI: No ID Found -
Protein & Cell Jul 2013The fungus Trichophyton schoenleinii (T. schoenleinii) is the causative agent of Trichophytosis and Tinea favosa of the scalp in certain regions of Eurasia and Africa....
The fungus Trichophyton schoenleinii (T. schoenleinii) is the causative agent of Trichophytosis and Tinea favosa of the scalp in certain regions of Eurasia and Africa. Human innate immune system plays an important role in combating with various pathogens including fungi. The inflammasome is one of the most critical arms of host innate immunity, which is a protein complex controlling maturation of IL-1β. To clarify whether T. schoenleinii is able to activate the inflammasome, we analyzed human monocytic cell line THP-1 for IL-1β production upon infection with T. schoenleinii strain isolated from Tinea favosa patients, and rapid IL-1β secretion from THP-1 cells was observed. Moreover, applying competitive inhibitors and gene specific silencing with shRNA, we found that T. schoenleinii induced IL-1β secretion, ASC pyroptosome formation as well as caspase-1 activation were all dependent on NLRP3. Cathepsin B activity, ROS production and K⁺ efflux were required for the inflammasome activation by T. schoenleinii. Our data thus reveal that the NLRP3 inflammasome plays an important role in host defense against T. schoenleinii, and suggest that manipulating NLRP3 signaling can be a novel approach for control of diseases caused by T. schoenleinii infection.
Topics: Animals; Bone Marrow Cells; Carrier Proteins; Caspase 1; Cell Line; Dendritic Cells; Enzyme Activation; Hot Temperature; Humans; Inflammasomes; Interleukin-1beta; Lysosomes; Mice; Monocytes; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; Signal Transduction; Trichophyton
PubMed: 23686720
DOI: 10.1007/s13238-013-2127-9 -
Anais Brasileiros de Dermatologia 2020Tinea capitis comprising of tinea favosa and kerion is mostly seen in school-aged children. Some tinea capitis often presented with insignificant findings under the...
Tinea capitis comprising of tinea favosa and kerion is mostly seen in school-aged children. Some tinea capitis often presented with insignificant findings under the naked eyes are easily overlooked. The authors describe an unusual case of tinea capitis caused by Trichophyton violaceum. The patient was an 8-year-old girl, with a history of pruritus on the scalp for more than one year. A diagnosis of tinea capitis was confirmed by clinical examination aided by dermoscopy, calcium fluorescent microscopy and culture. Comma and corkscrew hairs are two specific dermoscopic patterns of tinea capitis. The patient was treated with systemic itraconazole, topical application with 1% naftifine 0.25% ketoconazole cream followed after daily hair wash with 2% ketoconazole shampoo for 8 weeks.
Topics: Calcium; Child; Dermoscopy; Female; Humans; Microscopy, Fluorescence; Reproducibility of Results; Tinea Capitis; Trichophyton
PubMed: 32276798
DOI: 10.1016/j.abd.2019.06.013 -
Indian Journal of Dermatology,...Nannizzia (N.) incurvata (formerly Microsporum incurvatum) represents a geophilic dermatophyte which has been previously classified as belonging to the species complex...
Nannizzia (N.) incurvata (formerly Microsporum incurvatum) represents a geophilic dermatophyte which has been previously classified as belonging to the species complex of N. gypsea (formerly Microsporum gypseum). A 42-year-old Vietnamese female from Saxony, Germany, suffered from tinea corporis of the right buttock after she returned from a 2-week-visit to her homeland Vietnam. From skin scrapings of lesions, N. incurvata grew on Sabouraud's dextrose agar. Treatment by ciclopirox olamine cream twice daily for 4 weeks was successful. A 6-year-old Cambodian boy living near river Mekong with contact history to chicken, dogs and cattle suffered from tinea faciei and capitis. Symptoms of the favus-like tinea capitis and tinea faciei were erythema and scaly patches with areas of alopecia. N. incurvata grew on Sabouraud's dextrose agar. The boy was treated with oral terbinafine 125 mg daily, topical miconazole cream and ketoconazole shampoo. The symptoms healed within 4 weeks of treatment. Cultivation of the samples revealed growth of N. incurvata. For confirmation of species identification, the isolates were subject to sequencing of ITS (internal transcribed spacer) region of the rDNA, and addition of the "translation elongation factor 1 α" (TEF 1 α) gene. Sequencing of the ITS region showed 100% accordance with the sequence of N. incurvata deposited at the NCBI database under the accession number MF415405. N. incurvata is a rare, or might be underdiagnosed geophilic dermatophyte described in Sri Lanka and Vietnam until now. This is the first isolation of N. incurvata in Cambodia, and the first description of favus in a child due to this dermatophyte.
Topics: Adult; Arthrodermataceae; Cambodia; Child; DNA, Ribosomal; Female; Humans; Male; Sequence Analysis, DNA; Tinea; Tinea Favosa; Vietnam
PubMed: 32525102
DOI: 10.4103/ijdvl.IJDVL_954_18 -
Antimicrobial Agents and Chemotherapy Feb 2017Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We...
In Vitro Antifungal Susceptibility Profiles of 12 Antifungal Drugs against 55 Trichophyton schoenleinii Isolates from Tinea Capitis Favosa Patients in Iran, Turkey, and China.
Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We investigated the in vitro susceptibilities of 55 T. schoenleinii isolates collected over the last 30 years from Iran, Turkey, and China to 12 antifungals using the CLSI broth microdilution method. Our results revealed that terbinafine and ketoconazole were the most potent antifungal agents among those tested, independently of the geographic regions where strains were isolated.
Topics: Antifungal Agents; China; Humans; Iran; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Terbinafine; Tinea Favosa; Trichophyton; Turkey
PubMed: 27956429
DOI: 10.1128/AAC.01753-16