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Archivos Argentinos de Pediatria Apr 2024Tinea capitis is a dermatophytosis, which is more common in children. It is caused by dermatophytes that vary according to the region; the most frequently isolated...
Tinea capitis is a dermatophytosis, which is more common in children. It is caused by dermatophytes that vary according to the region; the most frequently isolated dermatophyte in our setting is Microsporum canis. Given its anthropophilic nature, its dissemination via interpersonal transmission and through the use of hair care tools is very common. In the course of the past year, an increase has been reported in the incidence of a pathogen that was very rare in our setting: Trichophyton tonsurans. Here we describe a retrospective study of cases of tinea capitis caused by Trichophyton tonsurans identified between September 2021 and March 2023 in the Department of Pediatric Dermatology at a general hospital of the City of Buenos Aires.
PubMed: 38608007
DOI: 10.5546/aap.2023-10254.eng -
The Journal of Allergy and Clinical... May 2024Leukocyte adhesion deficiency type 1 (LAD-1) is a congenital immunodeficiency leading to impaired trafficking of neutrophils to inflammation sites. Solitary or multiple...
BACKGROUND
Leukocyte adhesion deficiency type 1 (LAD-1) is a congenital immunodeficiency leading to impaired trafficking of neutrophils to inflammation sites. Solitary or multiple pyoderma gangrenosum (PG)-like skin ulcers (PGLUs) have been reported previously in 13 children (aged 0.5-19 years) with LAD-1.
OBJECTIVE
Our aim was to report the case of a 10-year-old boy presenting with PGLUs as the first manifestation of LAD-1 treated with ustekinumab.
METHODS
We obtained cytokine profiles.
RESULTS
PGLUs were triggered by cutaneous ringworm infection (). Skin biopsy samples showed increased intralesional expression of IL-17A, Il-23, and IL-1β as compared with their expression in healthy controls. After an unsuccessful attempt at treatment with oral methylprednisolone, ustekinumab induced regression of the ulcerations, associated with complete normalization of the cytokine profile.
CONCLUSIONS
PGLUs, triggered by ringworm infection, can be a late harbinger of LAD-1. Ustekinumab is a safe and effective therapeutic option for patients with LAD-1 and PGLUs while bridging the time until stem cell transplantation.
PubMed: 38560722
DOI: 10.1016/j.jacig.2024.100233 -
Actas Dermo-sifiliograficas Mar 2024
[Translated article] Outbreak of Tinea Capitis due to Trichophyton Tonsurans in Hairdressing Salons: Personal Experience and Description of Cases Found in a Solo Practicioner Clinic from Malaga, Spain.
Topics: Humans; Spain; Tinea Capitis; Arthrodermataceae; Disease Outbreaks; Trichophyton
PubMed: 38242429
DOI: 10.1016/j.ad.2024.01.020 -
Medical Mycology Journal 2023This is a report of the results of the epidemiological survey on dermatomycoses conducted in 2021. A total of 9,442 patients with dermatomycosis were reported for one...
This is a report of the results of the epidemiological survey on dermatomycoses conducted in 2021. A total of 9,442 patients with dermatomycosis were reported for one year. They include 8,151 (86.3%) with dermatophytosis, 796 (8.4%) with candidiasis, 484 (5.1%) with Malassezia infection, and 11 (0.1%) with deep cutaneous mycosis. In order, the most common types of dermatophytoses were tinea pedis (4,195 cases, 2,341 males and 1,854 females), tinea unguium (2,711 cases, 1,509 males and 1,202 females), tinea corporis (674 cases, 445 males and 229 females), tinea cruris (399 cases, 305 males and 94 females), tinea manus (125 cases, 78 males and 47 females), and tinea capitis (47 cases, 25 males and 22 females). The number of cases of tinea pedis and tinea unguium increased during the summer. A higher percentage of patients were aged 80 or older than in previous surveys. These findings may reflect the increasing percentage of elderly patients seen and the superannuation of the population. As in previous surveys, Trichophyton rubrum and Trichophyton interdigitale were the two most frequently isolated species of fungi causing dermatophytoses. Microsporum canis and Trichophyton tonsurans were the two species most often causing tinea capitis.Regarding cutaneous candidiasis, while candidal intertrigo was the most common in previous surveys, diaper candidiasis in the elderly was the most common in this survey. A background check revealed that this was because a facility included a semi-prophylactic approach to address diaper candidiasis occurring within the ward.Malassezia infections by Malassezia folliculitis clearly increased with each survey. The tendency of certain facilities with many reports of Malassezia folliculitis suggests that it is greatly affected by the presence of physicians familiar with the disease.
Topics: Male; Aged; Female; Humans; Tinea Pedis; Dermatomycoses; Onychomycosis; Japan; Tinea; Candidiasis, Cutaneous; Tinea Capitis; Candidiasis; Folliculitis; Trichophyton
PubMed: 38030276
DOI: 10.3314/mmj.23-00008 -
Clinical Case Reports Nov 2023Tinea capitis is a common dermatophyte infection of the scalp in children. It is an uncommon infection in adults and usually affects postmenopausal women and...
Tinea capitis is a common dermatophyte infection of the scalp in children. It is an uncommon infection in adults and usually affects postmenopausal women and immunocompromised patients. We report an immunocompetent elderly female with inflammatory tinea capitis caused by and review the literature for the past 5 years to describe the disease, its epidemiologic characteristics, dermatophyte species involved and treatment options used. The total number of cases was 11, including 8 women and 3 men, with an average age of 48.36. The most commonly isolated dermatophyte was , and most cases were treated successfully with oral terbinafine with no side effects. In our case, the diagnosis was established by direct examination, culture and histological examination. Remedy with itraconazole and prednisolone was very successful. Early diagnosis of tinea capitis in adults is necessary to provide early treatment and minimize sequelae of the disease.
PubMed: 38028093
DOI: 10.1002/ccr3.8205 -
Actas Dermo-sifiliograficas Mar 2024
Outbreak of Tinea Capitis due to Trichophyton Tonsurans in Hairdressing Salons: Personal Experience and Description of Cases Found in a Solo Practicioner Clinic from Malaga, Spain.
Topics: Humans; Spain; Tinea Capitis; Arthrodermataceae; Disease Outbreaks; Trichophyton
PubMed: 37923071
DOI: 10.1016/j.ad.2023.10.024 -
Pharmaceuticals (Basel, Switzerland) Oct 2023The aim of this work was to provide an overview of available information on the antibacterial and antifungal properties of extracts. A literature search of Scopus,... (Review)
Review
The aim of this work was to provide an overview of available information on the antibacterial and antifungal properties of extracts. A literature search of Scopus, PubMed/Medline, and Google Scholar for peer-reviewed articles published between January 2000 and June 2023 was undertaken. A total of 23 studies were eligible for inclusion in this review. Significant variation of antimicrobial activity depending on the tested species and strains, type of extract solvent, or plant organs utilized for the extract preparation was found. extracts were active against both Gram-positive and Gram-negative bacteria and showed antimycotic effects against the fungi of and and the dermatophytes spp. Greater susceptibility of Gram-positive than Gram-negative bacteria to fireweed extracts was found. A strong antibacterial effect was recorded for , , , , , , and including multi-drug resistant strains. extract might find practical application as an antimicrobial in wound healing, components of cosmetic products for human and animals, or as food preservatives.
PubMed: 37895890
DOI: 10.3390/ph16101419 -
Current Medical Mycology Mar 2023Among different clinical entities of dermatophytosis, tinea capitis (TC) is considered a major public health challenge in the world, especially in regions with poor...
BACKGROUND AND PURPOSE
Among different clinical entities of dermatophytosis, tinea capitis (TC) is considered a major public health challenge in the world, especially in regions with poor health and low income. Therefore, this study aimed to provide a retrospective analysis of the patients suspected of TC who were referred to the medical mycology laboratory of Mazandaran, a northern province of Iran.
MATERIALS AND METHODS
A retrospective analysis was performed on the patients suspected of TC who were referred to the medical mycology laboratory from July 2009 to April 2022. Hair roots and skin scrapings were collected from the participants. The laboratory diagnosis was confirmed by direct microscopic examination and culture. Finally, 921 out of 11095 (8.3%) patients were suspected of TC.
RESULTS
Based on the findings, TC was confirmed in 209 out of 921 patients (22.7%). In terms of gender, 209 TC patients (75.1%) were male. Moreover, the male to female ratio of TC patients was 1:3.0. (146/174, 83.91%) was the most etiological agent, followed by (13/174, 7.47%), (9/174, 5.17%), (3/174, 1.71%), (2/174, 1.15%) and (1/174, 0.57%). Besides, endothrix (77.0%) was the most prevalent type of hair invasion.
CONCLUSION
The results revealed the predominance of , as a causative agent of TC. Despite the prevalence of TC, the absence of appropriate consideration highlights that it is a neglected complication among children.
PubMed: 37867593
DOI: 10.18502/CMM.2023.345026.1395 -
Biomedica : Revista Del Instituto... Aug 2023Introduction. Tinea capitis is a mycosis of keratinized tissue, which affects the scalp and may cause alopecia, pruritus, and desquamation. This type of mycosis is more...
Introduction. Tinea capitis is a mycosis of keratinized tissue, which affects the scalp and may cause alopecia, pruritus, and desquamation. This type of mycosis is more frequent in school-age children, and it may represent a public health problem; the main etiological agents reported for Colombia are zoophilic dermatophytes. Objective. To characterize an outbreak of Tinea capitis in 32 children from a rural school in the department of Cauca. Materials and methods. We conducted an epidemiological field study using a structured survey to characterize sociodemographic aspects and predisposing factors for this mycosis. We collected samples of affected scalp scales and hair for mycological studies. The children and the general population received recommendations, about these mycoses’ prevention, from Cauca’s health authorities and the local hospital. The parents verbally approved the informed consent. Results. The etiological agent isolated in 63% of the collected samples was Trichophyton tonsurans, an anthropophilic dermatophyte, and the main predisposing factor was sharing razors (87.5%). Conclusions. Ideally, mycological studies define the etiological agent to propose therapeutics and recommendations in agreement with management guidelines. Implementation of multidisciplinary measures to control the outbreak and educate the population is required.
Topics: Child; Humans; Colombia; Tinea Capitis; Disease Outbreaks; Hair; Public Health
PubMed: 37721918
DOI: 10.7705/biomedica.6793 -
Medical Mycology Journal 2023The patient was a 13-year-old boy who was a member of the judo club at his junior high school. Approximately 1 week prior to his presentation, he developed multiple...
The patient was a 13-year-old boy who was a member of the judo club at his junior high school. Approximately 1 week prior to his presentation, he developed multiple erythematous pilaris papules on his occipital area and was treated by a local doctor. The erythematous lesions expanded to 10 × 10 cm, showing granulation with drainage and strong spontaneous pain. At this point, he visited our hospital. He was diagnosed with kerion celsi due to Trichophyton tonsurans by fungal examination. The patient was treated with terbinafine (125 mg/day) for 6 weeks, and a brush test at 6 weeks was negative. All 18 members of the judo club, including this patient, were investigated; brush tests were positive in 4 cases, and one was positive for tinea corporis alone. The patient's family members parents were both negative. When an athlete is diagnosed with ringworm, T. tonsurans infection should be considered, and testing and treatment of family members and fellow athletes should be carried out to prevent the spread of infection.
Topics: Male; Humans; Adolescent; Tinea Capitis; Terbinafine; Athletes; Drainage
PubMed: 37648501
DOI: 10.3314/mmj.22-00032