-
Journal of the International Society of... May 2019In search of the right nutrition for the athlete, numerous nutritional strategies and diets were discussed over time. However, the influence of plant-based diets,... (Comparative Study)
Comparative Study
BACKGROUND
In search of the right nutrition for the athlete, numerous nutritional strategies and diets were discussed over time. However, the influence of plant-based diets, especially veganism, on exercise capacity has not been clarified.
METHODS
We conducted a cross-sectional study to compare the exercise capacity of vegan (VEG, n = 24), lacto-ovo-vegetarian (LOV, n = 26) and omnivorous (OMN, n = 26) recreational runners. To determine maximal exercise capacity, participants performed an incremental exercise test on a bicycle ergometer until voluntary exhaustion. During the test capillary blood samples were taken at several time points for the measurement of arterial lactate [lac] and glucose [glc] concentrations. To determine nutrient intake, a 24 h dietary recall was conducted.
RESULTS
The groups showed comparable training habits in terms of training frequency (mean 3.08 ± 0.90 time/wk., p = 0.735), time (mean 2.93 ± 1.34 h/wk., p = 0.079) and running distance (mean 29.5 ± 14.3 km/wk., p = 0.054). Moreover, similar maximum power output (P) was observed in all three groups (OMN: 4.15 ± 0.48 W/kg, LOV: 4.20 ± 0.47 W/kg, VEG: 4.16 ± 0.55 W/kg; p = 0.917) and no differences regarding [lac] throughout the exercise test and maximum lactate could be observed between the groups (OMN: 11.3 ± 2.19 mmol/l, LOV: 11.0 ± 2.59 mmol/l, VEG: 11.9 ± 1.98 mmol/l; p = 0.648).
CONCLUSION
The data indicate that each examined diet has neither advantages nor disadvantages with regard to exercise capacity. These results suggest that a vegan diet can be a suitable alternative for ambitious recreational runners.
TRIAL REGISTRATION
German Clinical Trials Register ( DRKS00012377 ). Registered on 28 April 2017.
Topics: Adult; Athletic Performance; Cross-Sectional Studies; Diet; Energy Intake; Exercise Tolerance; Female; Humans; Male; Running; Vegans; Vegetarians; Young Adult
PubMed: 31109329
DOI: 10.1186/s12970-019-0289-4 -
The American Journal of Clinical... May 2009Low-fat vegetarian and vegan diets are associated with weight loss, increased insulin sensitivity, and improved cardiovascular health. (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
Low-fat vegetarian and vegan diets are associated with weight loss, increased insulin sensitivity, and improved cardiovascular health.
OBJECTIVE
We compared the effects of a low-fat vegan diet and conventional diabetes diet recommendations on glycemia, weight, and plasma lipids.
DESIGN
Free-living individuals with type 2 diabetes were randomly assigned to a low-fat vegan diet (n = 49) or a diet following 2003 American Diabetes Association guidelines (conventional, n = 50) for 74 wk. Glycated hemoglobin (Hb A(1c)) and plasma lipids were assessed at weeks 0, 11, 22, 35, 48, 61, and 74. Weight was measured at weeks 0, 22, and 74.
RESULTS
Weight loss was significant within each diet group but not significantly different between groups (-4.4 kg in the vegan group and -3.0 kg in the conventional diet group, P = 0.25) and related significantly to Hb A(1c) changes (r = 0.50, P = 0.001). Hb A(1c) changes from baseline to 74 wk or last available values were -0.34 and -0.14 for vegan and conventional diets, respectively (P = 0.43). Hb A(1c) changes from baseline to last available value or last value before any medication adjustment were -0.40 and 0.01 for vegan and conventional diets, respectively (P = 0.03). In analyses before alterations in lipid-lowering medications, total cholesterol decreased by 20.4 and 6.8 mg/dL in the vegan and conventional diet groups, respectively (P = 0.01); LDL cholesterol decreased by 13.5 and 3.4 mg/dL in the vegan and conventional groups, respectively (P = 0.03).
CONCLUSIONS
Both diets were associated with sustained reductions in weight and plasma lipid concentrations. In an analysis controlling for medication changes, a low-fat vegan diet appeared to improve glycemia and plasma lipids more than did conventional diabetes diet recommendations. Whether the observed differences provide clinical benefit for the macro- or microvascular complications of diabetes remains to be established. This trial was registered at clinicaltrials.gov as NCT00276939.
Topics: Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Type 2; Diet Records; Diet, Fat-Restricted; Diet, Vegetarian; Dietary Fats; Dietary Supplements; Glycated Hemoglobin; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Time Factors; Vitamin B 12; Weight Loss
PubMed: 19339401
DOI: 10.3945/ajcn.2009.26736H -
The Journal of Nutrition Sep 2022The 2020-2025 Dietary Guidelines for Americans (2020 DGA) recommend 3 dietary patterns for Americans, including a Healthy Vegetarian Dietary Pattern (HVDP).
BACKGROUND
The 2020-2025 Dietary Guidelines for Americans (2020 DGA) recommend 3 dietary patterns for Americans, including a Healthy Vegetarian Dietary Pattern (HVDP).
OBJECTIVES
The objective of this study was to assess whether nutritionally adequate dairy-free and vegan adaptations to the HVDP can be modeled with foods already in the DGA.
METHODS
Using similar food pattern modeling procedures as the 2020 DGA, the nutrient composition of 2 alternative models-dairy-free and vegan-of the 1800-, 2000-, 2200-, and 2400-kcal/d HVDPs was assessed. The dairy food group was replaced with a dairy alternative group comprised of soy milk and soy yogurt fortified with calcium, vitamin A, and vitamin D. For the vegan model, eggs were replaced with equal proportions of vegetarian protein foods.
RESULTS
Dairy-free and vegan models required minimal changes to the HVDP. Cup-equivalents and/or ounce-equivalents of vegetables, fruits, grains, oils, and discretionary calories remained unchanged. Content of total fat, polyunsaturated fat, linoleic acid (18:2n-6), linolenic acid, iron, copper, vitamin D, riboflavin, vitamin B-12, and vitamin K increased in both models by ≥10% (all comparisons relative to the original HVDP). Choline increased ≥25% in the dairy-free models. Protein decreased 11% in both 1800-kcal/d models and 10% in both 2000-kcal/d models. Sodium, cholesterol, zinc, and phosphorus decreased across all energy levels in both models, and selenium decreased in the vegan model. Carbohydrate, fiber, saturated fat, EPA, DHA, calcium, magnesium, potassium, vitamin A, vitamin E, vitamin C, thiamin, folate, and vitamin B-6 changed ≤10%. Both models contained adequate nutrients to meet Dietary Reference Intakes (DRIs) for most age and sex groups for which 1800-, 2000-, 2200-, and 2400-kcal/d diets are appropriate. Zinc was the only nutrient below the DRI for males.
CONCLUSIONS
The dairy-free and vegan HVDP models could help adults who do not consume dairy foods and/or other animal products to meet nutrition recommendations.
Topics: Calcium; Calcium, Dietary; Diet; Diet, Vegetarian; Humans; Male; United States; United States Department of Agriculture; Vegans; Vitamin A; Vitamin D; Vitamins; Zinc
PubMed: 35485767
DOI: 10.1093/jn/nxac100 -
Translational Psychiatry Sep 2019Western societies notice an increasing interest in plant-based eating patterns such as vegetarian and vegan, yet potential effects on the body and brain are a matter of...
Western societies notice an increasing interest in plant-based eating patterns such as vegetarian and vegan, yet potential effects on the body and brain are a matter of debate. Therefore, we systematically reviewed existing human interventional studies on putative effects of a plant-based diet on the metabolism and cognition, and what is known about the underlying mechanisms. Using the search terms "plant-based OR vegan OR vegetarian AND diet AND intervention" in PubMed filtered for clinical trials in humans retrieved 205 studies out of which 27, plus an additional search extending the selection to another five studies, were eligible for inclusion based on three independent ratings. We found robust evidence for short- to moderate-term beneficial effects of plant-based diets versus conventional diets (duration ≤ 24 months) on weight status, energy metabolism and systemic inflammation in healthy participants, obese and type-2 diabetes patients. Initial experimental studies proposed novel microbiome-related pathways, by which plant-based diets modulate the gut microbiome towards a favorable diversity of bacteria species, yet a functional "bottom up" signaling of plant-based diet-induced microbial changes remains highly speculative. In addition, little is known, based on interventional studies about cognitive effects linked to plant-based diets. Thus, a causal impact of plant-based diets on cognitive functions, mental and neurological health and respective underlying mechanisms has yet to be demonstrated. In sum, the increasing interest for plant-based diets raises the opportunity for developing novel preventive and therapeutic strategies against obesity, eating disorders and related comorbidities. Still, putative effects of plant-based diets on brain health and cognitive functions as well as the underlying mechanisms remain largely unexplored and new studies need to address these questions.
Topics: Brain; Cognition; Diet, Vegan; Diet, Vegetarian; Humans
PubMed: 31515473
DOI: 10.1038/s41398-019-0552-0 -
PloS One 2016Several intervention studies have suggested that vegetarian or vegan diets have clinical benefits, particularly in terms of glycemic control, in patients with type 2... (Randomized Controlled Trial)
Randomized Controlled Trial
OBJECTIVE
Several intervention studies have suggested that vegetarian or vegan diets have clinical benefits, particularly in terms of glycemic control, in patients with type 2 diabetes (T2D); however, no randomized controlled trial has been conducted in Asians who more commonly depend on plant-based foods, as compared to Western populations. Here, we aimed to compare the effect of a vegan diet and conventional diabetic diet on glycemic control among Korean individuals.
MATERIALS AND METHODS
Participants diagnosed with T2D were randomly assigned to follow either a vegan diet (excluding animal-based food including fish; n = 46) or a conventional diet recommended by the Korean Diabetes Association 2011 (n = 47) for 12 weeks. HbA1c levels were measured at weeks 0, 4, and 12, and the primary study endpoint was the change in HbA1c levels over 12 weeks.
RESULTS
The mean HbA1c levels at weeks 0, 4, and 12 were 7.7%, 7.2%, and 7.1% in the vegan group, and 7.4%, 7.2%, and 7.2% in the conventional group, respectively. Although both groups showed significant reductions in HbA1C levels, the reductions were larger in the vegan group than in the conventional group (-0.5% vs. -0.2%; p-for-interaction = 0.017). When only considering participants with high compliance, the difference in HbA1c level reduction between the groups was found to be larger (-0.9% vs. -0.3%). The beneficial effect of vegan diets was noted even after adjusting for changes in total energy intake or waist circumference over the 12 weeks.
CONCLUSION
Both diets led to reductions in HbA1c levels; however, glycemic control was better with the vegan diet than with the conventional diet. Thus, the dietary guidelines for patients with T2D should include a vegan diet for the better management and treatment. However, further studies are needed to evaluate the long-term effects of a vegan diet, and to identify potential explanations of the underlying mechanisms.
TRIAL REGISTRATION
CRiS KCT0001771.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Diet, Diabetic; Diet, Vegan; Female; Food Analysis; Glycated Hemoglobin; Humans; Male; Middle Aged; Oryza
PubMed: 27253526
DOI: 10.1371/journal.pone.0155918 -
Molecules (Basel, Switzerland) Mar 2021There is a growing global need to shift from animal- towards plant-based diets. The main motivations are environmental/sustainability-, human health- and animal welfare... (Review)
Review
There is a growing global need to shift from animal- towards plant-based diets. The main motivations are environmental/sustainability-, human health- and animal welfare concerns. The aim is to replace traditional animal-based food with various alternatives, predominantly plant-based analogs. The elevated consumption of fish and seafood, leads to negative impacts on the ecosystem, due to dwindling biodiversity, environmental damage and fish diseases related to large-scale marine farming, and increased intake of toxic substances, particularly heavy metals, which accumulate in fish due to water pollution. While these facts lead to increased awareness and rising dietary shifts towards vegetarian and vegan lifestyles, still the majority of seafood consumers seek traditional products. This encourages the development of plant-based analogs for fish and seafood, mimicking the texture and sensorial properties of fish-meat, seafood, or processed fish products. Mimicking the internal structure and texture of fish or seafood requires simulating their nanometric fibrous-gel structure. Common techniques of structuring plant-based proteins into such textures include hydrospinning, electrospinning, extrusion, and 3D printing. The conditions required in each technique, the physicochemical and functional properties of the proteins, along with the use of other non-protein functional ingredients are reviewed. Trends and possible future developments are discussed.
Topics: Animals; Diet, Vegan; Diet, Vegetarian; Fish Products; Food Ingredients; Food Preferences; Food Technology; Humans; Plant Proteins, Dietary; Printing, Three-Dimensional; Seafood; Soy Foods
PubMed: 33809067
DOI: 10.3390/molecules26061559 -
Advances in Nutrition (Bethesda, Md.) Jun 2022Consumers are increasingly encouraged to consume more plant-based foods and lower their consumption of foods from animal origin. Concurrently, older adults are...
Consumers are increasingly encouraged to consume more plant-based foods and lower their consumption of foods from animal origin. Concurrently, older adults are recommended to consume an adequate amount of high-quality dietary protein for the prevention of age-related muscle loss. In the current Perspective article, we discuss why it may not be preferred to consume a vegan diet at an older age. Our perspective is based on the proposed lower bioavailability and functionality of proteins in a vegan diet due to the matrix of the whole-food protein sources, the lower essential amino acid (EAA) content, and specific EAA deficiencies in proteins derived from plant-based foods. We propose that a vegan diet increases the risk of an inadequate protein intake at an older age and that current strategies to improve the anabolic properties of plant-based foods are not feasible for many older adults. We provide recommendations for further research to substantiate the remaining knowledge gaps regarding the consequences of a vegan diet on skeletal muscle mass and strength at an older age.
Topics: Aged; Amino Acids, Essential; Animals; Diet, Vegan; Dietary Proteins; Eating; Humans; Muscle, Skeletal
PubMed: 35108354
DOI: 10.1093/advances/nmac009 -
Nutrition & Diabetes Nov 2018A plant-based diet is an effective strategy in the treatment of obesity. In this 16-week randomized clinical trial, we tested the effect of a plant-based diet on body... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND AND OBJECTIVES
A plant-based diet is an effective strategy in the treatment of obesity. In this 16-week randomized clinical trial, we tested the effect of a plant-based diet on body composition and insulin resistance. As a part of this trial, we investigated the role of plant protein on these outcomes.
SUBJECTS AND METHODS
Overweight participants (n = 75) were randomized to follow a plant-based (n = 38) or a control diet (n = 37). Dual X-ray Absorptiometry assessed body composition, Homeostasis Model Assessment (HOMA-IR) assessed insulin resistance, and a linear regression model was used to test the relationship between protein intake, body composition, and insulin resistance.
RESULTS
The plant-based vegan diet proved to be superior to the control diet in improving body weight, fat mass, and insulin resistance markers. Only the vegan group showed significant reductions in body weight (treatment effect -6.5 [95% CI -8.9 to -4.1] kg; Gxt, p < 0.001), fat mass (treatment effect -4.3 [95% CI -5.4 to -3.2] kg; Gxt, p < 0.001), and HOMA-IR (treatment effect -1.0 [95% CI -1.2 to -0.8]; Gxt, p = 0.004). The decrease in fat mass was associated with an increased intake of plant protein and decreased intake of animal protein (r = -0.30, p = 0.011; and r = +0.39, p = 0.001, respectively). In particular, decreased % leucine intake was associated with a decrease in fat mass (r = +0.40; p < 0.001), in both unadjusted and adjusted models for changes in BMI and energy intake. In addition, decreased % histidine intake was associated with a decrease in insulin resistance (r = +0.38; p = 0.003), also independent of changes in BMI and energy intake.
CONCLUSIONS
These findings provide evidence that plant protein, as a part of a plant-based diet, and the resulting limitation of leucine and histidine intake are associated with improvements in body composition and reductions in both body weight and insulin resistance.
Topics: Adult; Aged; Body Composition; Body Weight; Diet, Vegan; Female; Humans; Insulin Resistance; Male; Middle Aged; Overweight; Treatment Outcome; Weight Loss
PubMed: 30405108
DOI: 10.1038/s41387-018-0067-4 -
Tidsskrift For Den Norske Laegeforening... May 2022
Topics: Breast Feeding; Diet; Diet, Vegan; Diet, Vegetarian; Female; Follow-Up Studies; Humans; Infant; Mothers; Pregnancy; Pregnant Women; Vegetarians
PubMed: 35510463
DOI: 10.4045/tidsskr.21.0847 -
Journal of Food Science Oct 2022The 2020 Dietary Guidelines for Americans (DGA) recommends a Healthy Vegetarian Dietary Pattern (HVDP) but does not provide guidance for dairy-free vegetarian...
The 2020 Dietary Guidelines for Americans (DGA) recommends a Healthy Vegetarian Dietary Pattern (HVDP) but does not provide guidance for dairy-free vegetarian (ovo-vegetarian) or vegan diets. A recent study from our lab modeled ovo-vegetarian and vegan HVDPs for healthy adults and found minimal impacts on nutrient content. However, since these models provide only recommendations for food group amounts, the objective of this study was to determine the feasibility of implementing the 2000 kcal ovo-vegetarian and vegan models by developing sample menus and evaluating them for nutrient adequacy and diet quality. We implemented a search strategy for ovo-vegetarian and vegan recipes on the MyPlate.gov website, using the most frequently consumed foods from each food group as a guide. We then developed 5-day sample menus for each model and analyzed these menus for diet quality using the Healthy Eating Index Score-2015 (HEI-2015) and nutrient content. The HEI-2015 scores were 99.4 and 98.4 for the vegan and ovo-vegetarian menus, respectively. These sample menus did not achieve a perfect score of 100 due to sodium and refined grains (both menus), added sugars (ovo-vegetarian menu only), and fatty acid profiles (vegan menu only). Mean total energy was 1860 kcal (vegan) and 1880 kcal (ovo-vegetarian). Amounts of all macronutrients were within the Acceptable Macronutrient Distribution Ranges, but amounts of some micronutrients were below 90% of recommended levels. Healthy adults may be able to follow ovo-vegetarian and vegan diets with careful planning, but this study reveals challenges in meeting micronutrient needs with these eating patterns. PRACTICAL APPLICATION: This study assessed the quality and nutrient adequacy of sample vegan and dairy-free vegetarian menus developed based on adaptations of the 2000 kcal vegetarian dietary pattern from the 2020 Dietary Guidelines for Americans. We found that our sample vegan and dairy-free vegetarian menus, created with publicly available resources, contained enough servings of fruits, vegetables, grains, protein foods, dairy, and oils, but did not provide enough vitamin D, vitamin E, choline, zinc (for males), and iron (for females). Following vegan and ovo-vegetarian diets requires careful planning to ensure sources of these micronutrients are included in adequate amounts.
Topics: Adult; Male; Female; Humans; United States; Nutritive Value; Vegans; United States Department of Agriculture; Micronutrients; Vitamin D; Fatty Acids; Vitamin E; Iron; Sodium; Zinc; Choline; Sugars; Oils
PubMed: 36102227
DOI: 10.1111/1750-3841.16314